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The map label for this gene is rpe [H]

Identifier: 116872124

GI number: 116872124

Start: 731336

End: 732007

Strand: Direct

Name: rpe [H]

Synonym: lwe0704

Alternate gene names: 116872124

Gene position: 731336-732007 (Clockwise)

Preceding gene: 116872122

Following gene: 116872125

Centisome position: 25.99

GC content: 34.97

Gene sequence:

>672_bases
ATGACAAAGAAATTGCTTTGCCCCTCAATGATGTGTGCTGATTTTTCTAATCTCCAAAAGGAAATTGAAGAACTAGACCG
AGCTGGAAGTGACATCTTTCATATAGATATAATGGATGGTGAATTTGTACCGAGCTTTGGCATGGGATTGCAAGATTTTA
AAGAAATTCGAAATAAAACGCAGAAACTAGTGGATGTTCATTTAATGATAATGAATCCAGGTAACTATGTGGAGTTATTT
GCTGATTCGGGTGCCGATATTATTTATATTCATCCAGAAGCAGATAAACATCCAGCAAGAACTTTAGACAAAATACGAAA
AAAAGGGAAGAAAACAGGTGTGGCTATTAATCCTGGAACTGCTATTTCTACGATAAAAGAACTTTTGCCATTAGTAGATT
ATTTGATGGTGATGACTGTTAATCCGGGCTTTTCGGGTCAAACGTATCTTGATTATGTGGATGACAAAATAATAGAACTG
GTTCAATTAAAAAAGAAATATCCCTTTGAAATTATGGTCGATGGGGCTATATCTCCAGAAAAAATTGCTAAACTTTCTAA
AATTGGCGTCCGAGGATTTGTACTTGGAACCTCAGCGCTATTTGGTAAAAAAGAGGACTATGCTAAAATTATTAAACATT
TAAAACAAGAAGATATGGAGGAAGTACGATGA

Upstream 100 bases:

>100_bases
ATATATTTAACCAGAAAATGGTAAAACGATTACCCGTACAGACTTTCCTTTTTTATTTATAGCATGAGTAATCGTTATCT
CAAAGGAGTGAATACATATA

Downstream 100 bases:

>100_bases
AAATTGCGATTGGAAATGATCATGTTGGTATAGAACTTAAGCCTATTATTATCCGATTTTTAAAGGAATTAGGTCATGAA
GTAGAAGATTTTGGTGCTTT

Product: ribulose-5-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTKKLLCPSMMCADFSNLQKEIEELDRAGSDIFHIDIMDGEFVPSFGMGLQDFKEIRNKTQKLVDVHLMIMNPGNYVELF
ADSGADIIYIHPEADKHPARTLDKIRKKGKKTGVAINPGTAISTIKELLPLVDYLMVMTVNPGFSGQTYLDYVDDKIIEL
VQLKKKYPFEIMVDGAISPEKIAKLSKIGVRGFVLGTSALFGKKEDYAKIIKHLKQEDMEEVR

Sequences:

>Translated_223_residues
MTKKLLCPSMMCADFSNLQKEIEELDRAGSDIFHIDIMDGEFVPSFGMGLQDFKEIRNKTQKLVDVHLMIMNPGNYVELF
ADSGADIIYIHPEADKHPARTLDKIRKKGKKTGVAINPGTAISTIKELLPLVDYLMVMTVNPGFSGQTYLDYVDDKIIEL
VQLKKKYPFEIMVDGAISPEKIAKLSKIGVRGFVLGTSALFGKKEDYAKIIKHLKQEDMEEVR
>Mature_222_residues
TKKLLCPSMMCADFSNLQKEIEELDRAGSDIFHIDIMDGEFVPSFGMGLQDFKEIRNKTQKLVDVHLMIMNPGNYVELFA
DSGADIIYIHPEADKHPARTLDKIRKKGKKTGVAINPGTAISTIKELLPLVDYLMVMTVNPGFSGQTYLDYVDDKIIELV
QLKKKYPFEIMVDGAISPEKIAKLSKIGVRGFVLGTSALFGKKEDYAKIIKHLKQEDMEEVR

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=31.1320754716981, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=28.7735849056604, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=27.810650887574, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1790523, Length=204, Percent_Identity=36.2745098039216, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=35.9090909090909, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790754, Length=209, Percent_Identity=26.7942583732057, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=201, Percent_Identity=36.318407960199, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6322341, Length=237, Percent_Identity=35.4430379746835, Blast_Score=145, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24586301, Length=210, Percent_Identity=34.2857142857143, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 25116; Mature: 24985

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKLLCPSMMCADFSNLQKEIEELDRAGSDIFHIDIMDGEFVPSFGMGLQDFKEIRNKT
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
QKLVDVHLMIMNPGNYVELFADSGADIIYIHPEADKHPARTLDKIRKKGKKTGVAINPGT
HHHHEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEECCCH
AISTIKELLPLVDYLMVMTVNPGFSGQTYLDYVDDKIIELVQLKKKYPFEIMVDGAISPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
KIAKLSKIGVRGFVLGTSALFGKKEDYAKIIKHLKQEDMEEVR
HHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKKLLCPSMMCADFSNLQKEIEELDRAGSDIFHIDIMDGEFVPSFGMGLQDFKEIRNKT
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
QKLVDVHLMIMNPGNYVELFADSGADIIYIHPEADKHPARTLDKIRKKGKKTGVAINPGT
HHHHEEEEEEECCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEECCCH
AISTIKELLPLVDYLMVMTVNPGFSGQTYLDYVDDKIIELVQLKKKYPFEIMVDGAISPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
KIAKLSKIGVRGFVLGTSALFGKKEDYAKIIKHLKQEDMEEVR
HHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]