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The map label for this gene is flhA [H]

Identifier: 116872069

GI number: 116872069

Start: 678548

End: 680623

Strand: Direct

Name: flhA [H]

Synonym: lwe0649

Alternate gene names: 116872069

Gene position: 678548-680623 (Clockwise)

Preceding gene: 116872068

Following gene: 116872070

Centisome position: 24.11

GC content: 39.07

Gene sequence:

>2076_bases
ATGGGGAATTTAGGTGCTATAAAAAAATATTTTGCTATCTTGATTGCGGTCTCGTTTGTTATTGCACTTATTGTGCCATT
ACCTCCATTTGTGTTGGATTTAGTGCTTGTTACAATCTTGGCGTTCTCAGTGTTAGTTTACATGCGTGCCACATCAATTA
AAGATTGGAATGAGTTGAAGTCATTTCCTTCTTTGCTACTTTTGATGGGGATATTTCGGGTTTCGATAAATATTTCAACT
ACAAGGGCAATTTTAACTACTGGAGATCCTGGGCAAGTAATTAAGCAATTTGGGAACTTTGTTATTGGCAGTAATTTTGT
TGTTGGGATTGTTATTTTCATTATTTTAATCGTCTTTCAGTTTATTGTGGCAAATGGTTCATCGCGAACAGCCGAAGTGG
CCGCAAGATTTACGCTAGATGCTTTACCAGGTAAACAGATGGCGATTGATGCAGATCTGAATCAACGTTTGATTACAGAG
CCGGAAGCCAAAGAAAAGCGCGCATACTTGAATATGGAAACCGAATTCTACGGGGCAATGGATGGAGCTGGTAAATTTGT
AAAAGGTGACGTTCTTTTTACGGTTTTGCTTGCTGTTGTCAATATTGTTTTTGGGTTAATTGTCGGAATGGTTCAAGGTG
GACTTTCATTTGGGGAAGCCGCAGTTAAATATACGGAATTAACAATCGGGGATGGAATCGTAAGCCAGATTGGTTCACTA
CTAATGGCGATGTCAGCTGGGGTCATTGTTACTCGAGTATTTGATGGTTCAGATGACAATGTTGCTGTCGGGATTTTCAA
AGAATTAATGCAAAACTCTATCGTTGTATATACGCTTTCGGCAATGTTTATTTTAATGGGTGTCTTTAGTCCGCTTCCAG
CTATTCCATTTGTCGGTATTGGCGTAGTGCTTGGAATCATCGGCTATCGAACGCAATTTAATTTAAAGAAAAAAGAGCAG
TTGGAACTGGAAAAAGAAATGGAACTCATTCAGTCAGAAACGAATTCAGCCGAAGCAGAACATAACCAAGCATTCGGTGC
AGCGCGCGAGAAATTTCCGGTCGTTGTGGAACTTGGATTAAATATTGCCGCACTTGTGAAACAAAAAATGAACGGGGAAA
CGGCAAAAGATAAAGTCGTCTTGATGCGAAAATCTATTTTACAAGATTTAGGTATTGGCGTTCCAGGCATTAATTTTAAA
GATAATACGAGCTTTCAACCGCGAGGGAAATACGAAATTAAAGTAAAAGGTGTAGCAGTTGCGAGTGGTGTTTTGAAAGC
GGGGCATTTACTAGCTCTAAAAACACCGGGAGTGATGATGGACCTTGATGCTGAGCCAACGAAAGATCCGATTTTTGGGG
AAGATGGTTATTGGATTTTGCCAGGTGAGTTAGAAGATGCGCAAATGAAAAACTACCAAGTACTTGAGCCACTGAGTATT
TTAATTACCCACTTGGACGTCGTGCTTCGGAAAAATTTACATGAACTTCTGATGCGCCAGCAAATTAAAGATTTAATTGA
CGGACTTGCAGATGAAAACCAAATTTTAATTGATGAAATTAAGAAAAAAGAAATTGATTATTCGTTAATTCAAGGGGTAC
TTAGACAACTTTTGAAAGAAGGTATTTCAGTTCGTGATTTACCAACGATTGTCGAAGGGATTATTGACGGGCAAACGATT
TATCCAAATGATCTAGATGGGATTACAGCTTTTGTTAGGGAGCGGATTTCAAAAGTTATATGTGAACAAGCGAAAAACCA
AGATGGCAAAATTTATGCGCTACTGTTACAAGATTCAATTGAAATGGATACAGAAATTGTCAACACACCTTACTATGGCT
ACGCGCTGAACTGGGCGCTTGACAAAGAACTACCAATCATCCAAAAAGTAAGAGATACCGTGAATAAAGCGCAACTTACT
GGACGAGAACCAGTCATTTTAACAAGGCGGAAAGATTTTCGTTTTGGCTTTGTACGTGTTTTAGAAAGATATCAATTAGA
TGTGCCGGTGCTCTCTATTAGTGAACTGTCACCGGAAACAGAAGTGGAACAAATTGCGTTGATTGAACCAACTTGA

Upstream 100 bases:

>100_bases
GATGTTATTGAAGTGATGAAAGAATTGATGGACGCAGACAAAATCAAGTTCTAACAACATATGAGCGACCTTTCTAAACT
TAGAAAAGGCAGGTTTCAAA

Downstream 100 bases:

>100_bases
TGAGGGAGGTAATCCGTAGAAATGGGAAAACATTTAGTAGAAAAGATGGAAATTTTTAAGGCGAATTCCAAGCGAGAAAT
ACATAAAAAAATTCGCTTAG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MGNLGAIKKYFAILIAVSFVIALIVPLPPFVLDLVLVTILAFSVLVYMRATSIKDWNELKSFPSLLLLMGIFRVSINIST
TRAILTTGDPGQVIKQFGNFVIGSNFVVGIVIFIILIVFQFIVANGSSRTAEVAARFTLDALPGKQMAIDADLNQRLITE
PEAKEKRAYLNMETEFYGAMDGAGKFVKGDVLFTVLLAVVNIVFGLIVGMVQGGLSFGEAAVKYTELTIGDGIVSQIGSL
LMAMSAGVIVTRVFDGSDDNVAVGIFKELMQNSIVVYTLSAMFILMGVFSPLPAIPFVGIGVVLGIIGYRTQFNLKKKEQ
LELEKEMELIQSETNSAEAEHNQAFGAAREKFPVVVELGLNIAALVKQKMNGETAKDKVVLMRKSILQDLGIGVPGINFK
DNTSFQPRGKYEIKVKGVAVASGVLKAGHLLALKTPGVMMDLDAEPTKDPIFGEDGYWILPGELEDAQMKNYQVLEPLSI
LITHLDVVLRKNLHELLMRQQIKDLIDGLADENQILIDEIKKKEIDYSLIQGVLRQLLKEGISVRDLPTIVEGIIDGQTI
YPNDLDGITAFVRERISKVICEQAKNQDGKIYALLLQDSIEMDTEIVNTPYYGYALNWALDKELPIIQKVRDTVNKAQLT
GREPVILTRRKDFRFGFVRVLERYQLDVPVLSISELSPETEVEQIALIEPT

Sequences:

>Translated_691_residues
MGNLGAIKKYFAILIAVSFVIALIVPLPPFVLDLVLVTILAFSVLVYMRATSIKDWNELKSFPSLLLLMGIFRVSINIST
TRAILTTGDPGQVIKQFGNFVIGSNFVVGIVIFIILIVFQFIVANGSSRTAEVAARFTLDALPGKQMAIDADLNQRLITE
PEAKEKRAYLNMETEFYGAMDGAGKFVKGDVLFTVLLAVVNIVFGLIVGMVQGGLSFGEAAVKYTELTIGDGIVSQIGSL
LMAMSAGVIVTRVFDGSDDNVAVGIFKELMQNSIVVYTLSAMFILMGVFSPLPAIPFVGIGVVLGIIGYRTQFNLKKKEQ
LELEKEMELIQSETNSAEAEHNQAFGAAREKFPVVVELGLNIAALVKQKMNGETAKDKVVLMRKSILQDLGIGVPGINFK
DNTSFQPRGKYEIKVKGVAVASGVLKAGHLLALKTPGVMMDLDAEPTKDPIFGEDGYWILPGELEDAQMKNYQVLEPLSI
LITHLDVVLRKNLHELLMRQQIKDLIDGLADENQILIDEIKKKEIDYSLIQGVLRQLLKEGISVRDLPTIVEGIIDGQTI
YPNDLDGITAFVRERISKVICEQAKNQDGKIYALLLQDSIEMDTEIVNTPYYGYALNWALDKELPIIQKVRDTVNKAQLT
GREPVILTRRKDFRFGFVRVLERYQLDVPVLSISELSPETEVEQIALIEPT
>Mature_690_residues
GNLGAIKKYFAILIAVSFVIALIVPLPPFVLDLVLVTILAFSVLVYMRATSIKDWNELKSFPSLLLLMGIFRVSINISTT
RAILTTGDPGQVIKQFGNFVIGSNFVVGIVIFIILIVFQFIVANGSSRTAEVAARFTLDALPGKQMAIDADLNQRLITEP
EAKEKRAYLNMETEFYGAMDGAGKFVKGDVLFTVLLAVVNIVFGLIVGMVQGGLSFGEAAVKYTELTIGDGIVSQIGSLL
MAMSAGVIVTRVFDGSDDNVAVGIFKELMQNSIVVYTLSAMFILMGVFSPLPAIPFVGIGVVLGIIGYRTQFNLKKKEQL
ELEKEMELIQSETNSAEAEHNQAFGAAREKFPVVVELGLNIAALVKQKMNGETAKDKVVLMRKSILQDLGIGVPGINFKD
NTSFQPRGKYEIKVKGVAVASGVLKAGHLLALKTPGVMMDLDAEPTKDPIFGEDGYWILPGELEDAQMKNYQVLEPLSIL
ITHLDVVLRKNLHELLMRQQIKDLIDGLADENQILIDEIKKKEIDYSLIQGVLRQLLKEGISVRDLPTIVEGIIDGQTIY
PNDLDGITAFVRERISKVICEQAKNQDGKIYALLLQDSIEMDTEIVNTPYYGYALNWALDKELPIIQKVRDTVNKAQLTG
REPVILTRRKDFRFGFVRVLERYQLDVPVLSISELSPETEVEQIALIEPT

Specific function: Involved in the export of flagellum proteins [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=673, Percent_Identity=33.5809806835067, Blast_Score=328, Evalue=6e-91,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76235; Mature: 76103

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNLGAIKKYFAILIAVSFVIALIVPLPPFVLDLVLVTILAFSVLVYMRATSIKDWNELK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SFPSLLLLMGIFRVSINISTTRAILTTGDPGQVIKQFGNFVIGSNFVVGIVIFIILIVFQ
HHHHHHHHHHHHHHEEEEEEEEEEEECCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHHH
FIVANGSSRTAEVAARFTLDALPGKQMAIDADLNQRLITEPEAKEKRAYLNMETEFYGAM
HHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHEECCCHHHHCCC
DGAGKFVKGDVLFTVLLAVVNIVFGLIVGMVQGGLSFGEAAVKYTELTIGDGIVSQIGSL
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCHHHHHHHHH
LMAMSAGVIVTRVFDGSDDNVAVGIFKELMQNSIVVYTLSAMFILMGVFSPLPAIPFVGI
HHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCHHHHH
GVVLGIIGYRTQFNLKKKEQLELEKEMELIQSETNSAEAEHNQAFGAAREKFPVVVELGL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECC
NIAALVKQKMNGETAKDKVVLMRKSILQDLGIGVPGINFKDNTSFQPRGKYEIKVKGVAV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECEEH
ASGVLKAGHLLALKTPGVMMDLDAEPTKDPIFGEDGYWILPGELEDAQMKNYQVLEPLSI
HHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHH
LITHLDVVLRKNLHELLMRQQIKDLIDGLADENQILIDEIKKKEIDYSLIQGVLRQLLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GISVRDLPTIVEGIIDGQTIYPNDLDGITAFVRERISKVICEQAKNQDGKIYALLLQDSI
CCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
EMDTEIVNTPYYGYALNWALDKELPIIQKVRDTVNKAQLTGREPVILTRRKDFRFGFVRV
HCCHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
LERYQLDVPVLSISELSPETEVEQIALIEPT
HHHHHCCCCEEEHHHCCCCCCCCEEEEECCC
>Mature Secondary Structure 
GNLGAIKKYFAILIAVSFVIALIVPLPPFVLDLVLVTILAFSVLVYMRATSIKDWNELK
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SFPSLLLLMGIFRVSINISTTRAILTTGDPGQVIKQFGNFVIGSNFVVGIVIFIILIVFQ
HHHHHHHHHHHHHHEEEEEEEEEEEECCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHHH
FIVANGSSRTAEVAARFTLDALPGKQMAIDADLNQRLITEPEAKEKRAYLNMETEFYGAM
HHHCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHEECCCHHHHCCC
DGAGKFVKGDVLFTVLLAVVNIVFGLIVGMVQGGLSFGEAAVKYTELTIGDGIVSQIGSL
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEECCHHHHHHHHH
LMAMSAGVIVTRVFDGSDDNVAVGIFKELMQNSIVVYTLSAMFILMGVFSPLPAIPFVGI
HHHHHCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCHHHHH
GVVLGIIGYRTQFNLKKKEQLELEKEMELIQSETNSAEAEHNQAFGAAREKFPVVVELGL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECC
NIAALVKQKMNGETAKDKVVLMRKSILQDLGIGVPGINFKDNTSFQPRGKYEIKVKGVAV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECEEH
ASGVLKAGHLLALKTPGVMMDLDAEPTKDPIFGEDGYWILPGELEDAQMKNYQVLEPLSI
HHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHH
LITHLDVVLRKNLHELLMRQQIKDLIDGLADENQILIDEIKKKEIDYSLIQGVLRQLLKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GISVRDLPTIVEGIIDGQTIYPNDLDGITAFVRERISKVICEQAKNQDGKIYALLLQDSI
CCCCCHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCH
EMDTEIVNTPYYGYALNWALDKELPIIQKVRDTVNKAQLTGREPVILTRRKDFRFGFVRV
HCCHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
LERYQLDVPVLSISELSPETEVEQIALIEPT
HHHHHCCCCEEEHHHCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]