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The map label for this gene is macB [H]

Identifier: 116871779

GI number: 116871779

Start: 375957

End: 377123

Strand: Direct

Name: macB [H]

Synonym: lwe0359

Alternate gene names: 116871779

Gene position: 375957-377123 (Clockwise)

Preceding gene: 116871778

Following gene: 116871780

Centisome position: 13.36

GC content: 35.13

Gene sequence:

>1167_bases
ATGAGCCTATTTCAAAGTGTGAAACTTGCATTAAAACAACTTCTTTCCGCTAAATTTAGAACTTTTTTGACCATGTTAGG
AATTATTATTGGTGTTTTTTCTGTTATATTACTTGTGTCGATTGGTGAAGCTATTTCAAAAAATGTATCGACACAATTAG
GCGACATGGGCAGTAATTTAGTTTCTATTAGTTTTCAATCCGACAATCCAAATGAAAAATTCACTTATAAAGATGCCACT
AGTCTTCTGAAGGAAAGTGAGATTGGATCGCCAGAAGTCATGCGAAACATGGAAGTGAGAACTGGTGACAAAACAGCCAC
CAAACAAGTGACAGGAATCAATGAAGATTATGTTAGTATAAAAAATCTAGAACTTATATCAGGACGATTTTGCTCGTCGG
TAGATGTTCAATATGCACAAAAAGTAACGGTGATTGGTTCTGAGATTGCAAAGAGCTATTTTAAAAACCAAAATCCTATA
GGGAAATATGTACAAATTTCAGGAGCCAGGTATGTGGTTATTGGTGTTTTAAAAGAAAAAGGAGAGAGTTTATTTGGATC
AGCAGATAAGAAATTATTTATTCCCATATCTTCTGCAGTAAGGCTGTTTAAGTCTGATTCCATTGATTTGTATTATATTC
AAACGCAAACCACTGAACAAGTTTCAACTACAGTGGAACAAACAAAAGAGAAGATGAATCAACTTTTTCCAAATGATAAG
GAGGCATACACAGTCGTAAACCAGCAACAGGCATTAGATACATTTGATAATATTACAAAAACGCTTACGCTTGGGTTAGG
AGCAATAGCTGGAATTTCGCTCTTAGTTGGCGGAATTGGTATTATGAACATTATGCTTGTATCTGTTTCAGAGCGAACTC
GAGAAATTGGCATTAGAAAAGCAATTGGGGCGGGTAATCGGGCTATTTTAATGCAGTTTCTAATTGAATCTATTGTACTT
AGTTTATTAGGTGGAATTATTGGAATTTTATTAGGTATTTTTACAGCGCAACTAGTTACAGCAGTATCTAATTTTGAAAT
GCGAGTTTCTGCATCGACAATCCTTATTGCAGTTAGTTTTTCGATGTTTATTGGAGTAGTGTTTGGTGTAATTCCAGCGC
AGAAAGCATCGAAAAAAATGCCGATAGATGCGTTGCGTGCAGATTAA

Upstream 100 bases:

>100_bases
GAAATACGTTGATTATGATTACACATGACAAAACAATTGCTGAACAAGCGGAACGAATAATAGAAATAAAAGACGGAAAA
CTCCGTGAATGGAATAATCT

Downstream 100 bases:

>100_bases
CTTAAGGAGGCGTTTTGATGGAGATAGAAGAACAGTTGGATGATACTTGGGTTTTAATTGAAATTGTAAGCCTTGTAACT
AATGTAGAACGACAGAGACT

Product: ABC transporter, permease protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSLFQSVKLALKQLLSAKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLVSISFQSDNPNEKFTYKDAT
SLLKESEIGSPEVMRNMEVRTGDKTATKQVTGINEDYVSIKNLELISGRFCSSVDVQYAQKVTVIGSEIAKSYFKNQNPI
GKYVQISGARYVVIGVLKEKGESLFGSADKKLFIPISSAVRLFKSDSIDLYYIQTQTTEQVSTTVEQTKEKMNQLFPNDK
EAYTVVNQQQALDTFDNITKTLTLGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGAGNRAILMQFLIESIVL
SLLGGIIGILLGIFTAQLVTAVSNFEMRVSASTILIAVSFSMFIGVVFGVIPAQKASKKMPIDALRAD

Sequences:

>Translated_388_residues
MSLFQSVKLALKQLLSAKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLVSISFQSDNPNEKFTYKDAT
SLLKESEIGSPEVMRNMEVRTGDKTATKQVTGINEDYVSIKNLELISGRFCSSVDVQYAQKVTVIGSEIAKSYFKNQNPI
GKYVQISGARYVVIGVLKEKGESLFGSADKKLFIPISSAVRLFKSDSIDLYYIQTQTTEQVSTTVEQTKEKMNQLFPNDK
EAYTVVNQQQALDTFDNITKTLTLGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGAGNRAILMQFLIESIVL
SLLGGIIGILLGIFTAQLVTAVSNFEMRVSASTILIAVSFSMFIGVVFGVIPAQKASKKMPIDALRAD
>Mature_387_residues
SLFQSVKLALKQLLSAKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNLVSISFQSDNPNEKFTYKDATS
LLKESEIGSPEVMRNMEVRTGDKTATKQVTGINEDYVSIKNLELISGRFCSSVDVQYAQKVTVIGSEIAKSYFKNQNPIG
KYVQISGARYVVIGVLKEKGESLFGSADKKLFIPISSAVRLFKSDSIDLYYIQTQTTEQVSTTVEQTKEKMNQLFPNDKE
AYTVVNQQQALDTFDNITKTLTLGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRKAIGAGNRAILMQFLIESIVLS
LLGGIIGILLGIFTAQLVTAVSNFEMRVSASTILIAVSFSMFIGVVFGVIPAQKASKKMPIDALRAD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=395, Percent_Identity=33.4177215189873, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42151; Mature: 42020

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFQSVKLALKQLLSAKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VSISFQSDNPNEKFTYKDATSLLKESEIGSPEVMRNMEVRTGDKTATKQVTGINEDYVSI
EEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHCCCCCCHHHH
KNLELISGRFCSSVDVQYAQKVTVIGSEIAKSYFKNQNPIGKYVQISGARYVVIGVLKEK
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEHHC
GESLFGSADKKLFIPISSAVRLFKSDSIDLYYIQTQTTEQVSTTVEQTKEKMNQLFPNDK
CCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
EAYTVVNQQQALDTFDNITKTLTLGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRK
HHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAGNRAILMQFLIESIVLSLLGGIIGILLGIFTAQLVTAVSNFEMRVSASTILIAVSF
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHH
SMFIGVVFGVIPAQKASKKMPIDALRAD
HHHHHHHHHHCCCHHHCCCCCCHHHCCC
>Mature Secondary Structure 
SLFQSVKLALKQLLSAKFRTFLTMLGIIIGVFSVILLVSIGEAISKNVSTQLGDMGSNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VSISFQSDNPNEKFTYKDATSLLKESEIGSPEVMRNMEVRTGDKTATKQVTGINEDYVSI
EEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHCCCCCCHHHH
KNLELISGRFCSSVDVQYAQKVTVIGSEIAKSYFKNQNPIGKYVQISGARYVVIGVLKEK
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEEHHC
GESLFGSADKKLFIPISSAVRLFKSDSIDLYYIQTQTTEQVSTTVEQTKEKMNQLFPNDK
CCHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
EAYTVVNQQQALDTFDNITKTLTLGLGAIAGISLLVGGIGIMNIMLVSVSERTREIGIRK
HHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAGNRAILMQFLIESIVLSLLGGIIGILLGIFTAQLVTAVSNFEMRVSASTILIAVSF
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHH
SMFIGVVFGVIPAQKASKKMPIDALRAD
HHHHHHHHHHCCCHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA