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The map label for this gene is nrdD [H]

Identifier: 116871673

GI number: 116871673

Start: 273655

End: 275805

Strand: Direct

Name: nrdD [H]

Synonym: lwe0253

Alternate gene names: 116871673

Gene position: 273655-275805 (Clockwise)

Preceding gene: 116871669

Following gene: 116871674

Centisome position: 9.72

GC content: 39.19

Gene sequence:

>2151_bases
ATGTACGTGGAACAACTTAATGAACAAATGGTGATAAAAAGGGACGGCCGCAAAGCGAACTTCGATTTAATTAAAATCCG
TAATGCTGTCGAAGCATCTATGAAAGCAATTGATTTAGAGGATGAAACTTTCTTAGAAGAGATTTTGCTTGAGGTTGTAA
GTGAATTACCTAACAAGACAGATATGACCATCGATGAAATCCAGCATTGCGTCGAAAACACCTTAATGAAATCGACGTAT
CCTGATGTAGCGAGGGCTTACATAGAGTACCGCCATGACCGGGACCATGAGCGTGAAAACATCACAGATATGCACAAAAG
CGTAGAAAAATTATTACAAAAAGATAAAACAGTAGTCAACGAAAATGCCAACAAAGACGCAACAGTCTTTAACACCCAAC
GCGATTTGACAGCAGGAGCCGTAGCAAAAAGTTACGCATTAAAATACATGCTACCAAAACACGTATCGAACGCTCATTTA
AAAGGAGAAATTCATTTTCACGATTTAGACTACAGCCCATACCATGCAATGACTAACTGTTGCTTAATTGATATTGAAGG
CATGCTGAAAAAAGGATTTACGATTGGAAACGCTAATGTAGAAAGTCCAAAATCCATCCAAACAGCTACAGCGCAAATTG
CTCAAATAATCGCAAACGTAGCAAGTTCGCAGTATGGCGGCTGTTCAGTTGACCGAATTGATGAAGTATTATCCGTTTAT
GCGCGCCTGAACTTTGAAAAACACAAAAAAGACGCAGTAGAATGGGTCGTTCCAGAGAAACAAGAAGGCTATGCAGCGGA
GAAAACACGTAAAGATATTTATGATGCCATGCAAAGCTTAGAATACGAAATCAATACTTTATATACAAGTAATGGACAAA
CACCATTCGTAACACTGGGCTTCGGTCTTGGGCAAGATTGGTTCGCTCGTGAAATTCAAAAAGCAATCCTAAAAGTTCGG
ATTGGCGGGGTTGGAAAAGATAAACATACAGCGATTTTCCCGAAATTAGTATTTTCGATTCGTCGTGGCACTAACTTAAA
TGCGGCAGATTCAAACTATGATATTAAACAACTGGCGCTAGAATGCTCCTCTAAACGGATGTATCCAGATGTACTCAACT
ATGATTCACTGGTTCGTTTAACAGGTGATTTCAAAGTGCCAATGGGCTGTCGTTCCTTTTTACCGGCTTGGAAAAATGAG
AACGGAGAGCATGTGAACGCGGGAAGAAACAATCTTGGAGTCGTAACGCTAAATATTCCACGTATTGCTATTCAAAGTGG
TGGTAACAAAGATCGTTTCTGGGAAATTTTCCATGAACGTATGAAAACCGTCAAAGATGCACTACTTTTCCGTTTAAATC
GTGTACGTCAAGCACGCCCAGAAAATGCGCCAATTTTATATAAATACGGTGCTTTTGGCAAACGACTACAAGATGGCGAA
AATGTCGACCAACTTTTCAATAAAGAACGCTCCACGATTTCTATCGGCTATATTGGTCTATATGAAGCGGCAACTGTGTT
TTATGGTGGCGAATGGGAAGGCGATGCAGAAGCAAAAAACTTCACCCTTGATATTGTAAAAGAATTAAAAACGTATGCGG
ATGACTGGAAAGAAAAATATGGCTATTGGTTCAGTGTATATTCCACACCAAGTGAAAGCTTAACAGATCGTTTCAACCGT
TTAGATAAAGAAAAATATGGCGTCATTAAAGACATCACGGATAAAGACTATTATCAAAACTCTTTCCACTATGATGTTCG
TAAAAAAATCACTCCATTTGAGAAAATTGATTTTGAAAAAGACTATCCAGAATTTTGCTCTGGCGGATTCATTCATTATT
GTGAGTATCCAAAAATGGTTCACAACACGAAAGCGCTGGAAGCTGTATGGGATTACTCTTATGATCGCGTAGCTTATCTT
GGTACAAATACACCGATTGATAAATGTTACGAATGTGATTTTGAAGGGGAATTTGTGCCAACAGAAGAAGGCTTTAAGTG
TCCAAGTTGTGGGAATACAGACCCTGAAAAAGCAGACGTAGTTAAACGTACTTGTGGTTACTTAGGGAATCCAATGAAAC
GTCCGATGGTTCATGGACGTCATGTAGAAATTAGCAATCGTGTGAAACATATGGAGGATTTAGGTGAATAA

Upstream 100 bases:

>100_bases
AGTCCCAATTCAGAAAAAACCTCAGATATCATTACAAAAAAACTTCATATTGTGTTATATTATTAAAGCAGACACAATAT
ATAGTTAGTGGGGGATTATC

Downstream 100 bases:

>100_bases
CCCAAAACCGTGTGAATGGAAGTCGAATGAATTATCCAGAGGGTATATCGCTGACTATAAAGCATTTAATTTTGTTGACG
GGGAGGGCGTTCGGTGCAGT

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MYVEQLNEQMVIKRDGRKANFDLIKIRNAVEASMKAIDLEDETFLEEILLEVVSELPNKTDMTIDEIQHCVENTLMKSTY
PDVARAYIEYRHDRDHERENITDMHKSVEKLLQKDKTVVNENANKDATVFNTQRDLTAGAVAKSYALKYMLPKHVSNAHL
KGEIHFHDLDYSPYHAMTNCCLIDIEGMLKKGFTIGNANVESPKSIQTATAQIAQIIANVASSQYGGCSVDRIDEVLSVY
ARLNFEKHKKDAVEWVVPEKQEGYAAEKTRKDIYDAMQSLEYEINTLYTSNGQTPFVTLGFGLGQDWFAREIQKAILKVR
IGGVGKDKHTAIFPKLVFSIRRGTNLNAADSNYDIKQLALECSSKRMYPDVLNYDSLVRLTGDFKVPMGCRSFLPAWKNE
NGEHVNAGRNNLGVVTLNIPRIAIQSGGNKDRFWEIFHERMKTVKDALLFRLNRVRQARPENAPILYKYGAFGKRLQDGE
NVDQLFNKERSTISIGYIGLYEAATVFYGGEWEGDAEAKNFTLDIVKELKTYADDWKEKYGYWFSVYSTPSESLTDRFNR
LDKEKYGVIKDITDKDYYQNSFHYDVRKKITPFEKIDFEKDYPEFCSGGFIHYCEYPKMVHNTKALEAVWDYSYDRVAYL
GTNTPIDKCYECDFEGEFVPTEEGFKCPSCGNTDPEKADVVKRTCGYLGNPMKRPMVHGRHVEISNRVKHMEDLGE

Sequences:

>Translated_716_residues
MYVEQLNEQMVIKRDGRKANFDLIKIRNAVEASMKAIDLEDETFLEEILLEVVSELPNKTDMTIDEIQHCVENTLMKSTY
PDVARAYIEYRHDRDHERENITDMHKSVEKLLQKDKTVVNENANKDATVFNTQRDLTAGAVAKSYALKYMLPKHVSNAHL
KGEIHFHDLDYSPYHAMTNCCLIDIEGMLKKGFTIGNANVESPKSIQTATAQIAQIIANVASSQYGGCSVDRIDEVLSVY
ARLNFEKHKKDAVEWVVPEKQEGYAAEKTRKDIYDAMQSLEYEINTLYTSNGQTPFVTLGFGLGQDWFAREIQKAILKVR
IGGVGKDKHTAIFPKLVFSIRRGTNLNAADSNYDIKQLALECSSKRMYPDVLNYDSLVRLTGDFKVPMGCRSFLPAWKNE
NGEHVNAGRNNLGVVTLNIPRIAIQSGGNKDRFWEIFHERMKTVKDALLFRLNRVRQARPENAPILYKYGAFGKRLQDGE
NVDQLFNKERSTISIGYIGLYEAATVFYGGEWEGDAEAKNFTLDIVKELKTYADDWKEKYGYWFSVYSTPSESLTDRFNR
LDKEKYGVIKDITDKDYYQNSFHYDVRKKITPFEKIDFEKDYPEFCSGGFIHYCEYPKMVHNTKALEAVWDYSYDRVAYL
GTNTPIDKCYECDFEGEFVPTEEGFKCPSCGNTDPEKADVVKRTCGYLGNPMKRPMVHGRHVEISNRVKHMEDLGE
>Mature_716_residues
MYVEQLNEQMVIKRDGRKANFDLIKIRNAVEASMKAIDLEDETFLEEILLEVVSELPNKTDMTIDEIQHCVENTLMKSTY
PDVARAYIEYRHDRDHERENITDMHKSVEKLLQKDKTVVNENANKDATVFNTQRDLTAGAVAKSYALKYMLPKHVSNAHL
KGEIHFHDLDYSPYHAMTNCCLIDIEGMLKKGFTIGNANVESPKSIQTATAQIAQIIANVASSQYGGCSVDRIDEVLSVY
ARLNFEKHKKDAVEWVVPEKQEGYAAEKTRKDIYDAMQSLEYEINTLYTSNGQTPFVTLGFGLGQDWFAREIQKAILKVR
IGGVGKDKHTAIFPKLVFSIRRGTNLNAADSNYDIKQLALECSSKRMYPDVLNYDSLVRLTGDFKVPMGCRSFLPAWKNE
NGEHVNAGRNNLGVVTLNIPRIAIQSGGNKDRFWEIFHERMKTVKDALLFRLNRVRQARPENAPILYKYGAFGKRLQDGE
NVDQLFNKERSTISIGYIGLYEAATVFYGGEWEGDAEAKNFTLDIVKELKTYADDWKEKYGYWFSVYSTPSESLTDRFNR
LDKEKYGVIKDITDKDYYQNSFHYDVRKKITPFEKIDFEKDYPEFCSGGFIHYCEYPKMVHNTKALEAVWDYSYDRVAYL
GTNTPIDKCYECDFEGEFVPTEEGFKCPSCGNTDPEKADVVKRTCGYLGNPMKRPMVHGRHVEISNRVKHMEDLGE

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=703, Percent_Identity=53.3428165007112, Blast_Score=792, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 82167; Mature: 82167

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVEQLNEQMVIKRDGRKANFDLIKIRNAVEASMKAIDLEDETFLEEILLEVVSELPNKT
CCHHHHCCCEEEEECCCCCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
DMTIDEIQHCVENTLMKSTYPDVARAYIEYRHDRDHERENITDMHKSVEKLLQKDKTVVN
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHC
ENANKDATVFNTQRDLTAGAVAKSYALKYMLPKHVSNAHLKGEIHFHDLDYSPYHAMTNC
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHCE
CLIDIEGMLKKGFTIGNANVESPKSIQTATAQIAQIIANVASSQYGGCSVDRIDEVLSVY
EEEEEHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ARLNFEKHKKDAVEWVVPEKQEGYAAEKTRKDIYDAMQSLEYEINTLYTSNGQTPFVTLG
HHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEE
FGLGQDWFAREIQKAILKVRIGGVGKDKHTAIFPKLVFSIRRGTNLNAADSNYDIKQLAL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ECSSKRMYPDVLNYDSLVRLTGDFKVPMGCRSFLPAWKNENGEHVNAGRNNLGVVTLNIP
HHHCCCCCCHHCCCCCEEEEECCCCCCCCHHHHCCHHCCCCCCEECCCCCCEEEEEEECC
RIAIQSGGNKDRFWEIFHERMKTVKDALLFRLNRVRQARPENAPILYKYGAFGKRLQDGE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHCCCCC
NVDQLFNKERSTISIGYIGLYEAATVFYGGEWEGDAEAKNFTLDIVKELKTYADDWKEKY
CHHHHHCCCCCEEEEEEEEHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GYWFSVYSTPSESLTDRFNRLDKEKYGVIKDITDKDYYQNSFHYDVRKKITPFEKIDFEK
CEEEEEECCCCHHHHHHHHHHCHHHCCCHHCCCCCHHHCCCCCCHHHHHCCCHHHCCCCC
DYPEFCSGGFIHYCEYPKMVHNTKALEAVWDYSYDRVAYLGTNTPIDKCYECDFEGEFVP
CCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHEECCCCCCCCC
TEEGFKCPSCGNTDPEKADVVKRTCGYLGNPMKRPMVHGRHVEISNRVKHMEDLGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MYVEQLNEQMVIKRDGRKANFDLIKIRNAVEASMKAIDLEDETFLEEILLEVVSELPNKT
CCHHHHCCCEEEEECCCCCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
DMTIDEIQHCVENTLMKSTYPDVARAYIEYRHDRDHERENITDMHKSVEKLLQKDKTVVN
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHC
ENANKDATVFNTQRDLTAGAVAKSYALKYMLPKHVSNAHLKGEIHFHDLDYSPYHAMTNC
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHCE
CLIDIEGMLKKGFTIGNANVESPKSIQTATAQIAQIIANVASSQYGGCSVDRIDEVLSVY
EEEEEHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ARLNFEKHKKDAVEWVVPEKQEGYAAEKTRKDIYDAMQSLEYEINTLYTSNGQTPFVTLG
HHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCEEEEE
FGLGQDWFAREIQKAILKVRIGGVGKDKHTAIFPKLVFSIRRGTNLNAADSNYDIKQLAL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ECSSKRMYPDVLNYDSLVRLTGDFKVPMGCRSFLPAWKNENGEHVNAGRNNLGVVTLNIP
HHHCCCCCCHHCCCCCEEEEECCCCCCCCHHHHCCHHCCCCCCEECCCCCCEEEEEEECC
RIAIQSGGNKDRFWEIFHERMKTVKDALLFRLNRVRQARPENAPILYKYGAFGKRLQDGE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHCCCCC
NVDQLFNKERSTISIGYIGLYEAATVFYGGEWEGDAEAKNFTLDIVKELKTYADDWKEKY
CHHHHHCCCCCEEEEEEEEHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GYWFSVYSTPSESLTDRFNRLDKEKYGVIKDITDKDYYQNSFHYDVRKKITPFEKIDFEK
CEEEEEECCCCHHHHHHHHHHCHHHCCCHHCCCCCHHHCCCCCCHHHHHCCCHHHCCCCC
DYPEFCSGGFIHYCEYPKMVHNTKALEAVWDYSYDRVAYLGTNTPIDKCYECDFEGEFVP
CCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHEECCCCCCCCC
TEEGFKCPSCGNTDPEKADVVKRTCGYLGNPMKRPMVHGRHVEISNRVKHMEDLGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]