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The map label for this gene is yacO [H]

Identifier: 116871624

GI number: 116871624

Start: 217264

End: 218019

Strand: Direct

Name: yacO [H]

Synonym: lwe0204

Alternate gene names: 116871624

Gene position: 217264-218019 (Clockwise)

Preceding gene: 116871623

Following gene: 116871625

Centisome position: 7.72

GC content: 41.4

Gene sequence:

>756_bases
ATGGAACAAGAAAATGAGCAAGAATGGATTGGTGGAAGAAATCCCGTCCTTGAAGTGTTACGATCCGAAAGAGATATCCA
TAAAATATACGTACAAGAAGGTTCGCAAAAAGGCGTGTTAAAACAAGTATTAACGCTGGCTAAAGAACGCAAAATCCAAG
TCCAATTTGTGCCAAAGCAAAAGATTGAAAAAGTAGTGAGTGGCGCACATCAAGGTGTTGCAGCGCAAGTGGCAGCTTAT
CAGTATGCTGAACTTGATGATTTATTTGCGGCTGCCGAAGCAAAAGATGAAATGCCGTTTTTCATTATTCTAGATGAGCT
AGAAGATCCACATAACTTAGGATCCATAATGCGTACAGCAGATTCTGTTGGTGCTCATGGAATTATTATCCCGAAACGTC
GCGCTGTAGGATTAACGCAAACTGTAGCAAAAGCTAGTACTGGGGCGATGGAGTATGTTCCAGTAGTTCGTGTGACGAAT
ATGGTGCGGACGATGGAAGAGTTGCAAAAACGCGGATTATGGATTTTTGGAACAGATGCTAAAGGAAGCAGCGATTACCG
GACAATGGATGTAGATATGCCACTTGCTATTGTTATTGGTAGTGAAGGGTTCGGTATGAGCCGCTTAGTTAGAGAAAAAT
GTGATTTCCTAGTTCATTTACCAATGCGTGGAAAAGTTACATCGCTTAATGCTTCTGTTGCAGCCAGTTTGTTACTATAT
GAAGTTTATCGGAAACGTTTCCCACTGGAGAAATAA

Upstream 100 bases:

>100_bases
CGGTTCTTGGTTATCTTTATTTAGCAGGTGACATGAGACGTCTTCAAGAATGGATGGAAAAGGCACTAGAAATAGTTGAA
AAAGGAGTGGAAAACAATTA

Downstream 100 bases:

>100_bases
AGATGGAACAAATTCTGCTTGTTGACGGGTATAATGTGATTGGGGCTTGGCCAGAACTTAGTTTCTTAAAAGATCGTGAT
TTGGAAGCGGCGAGAGATAA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MEQENEQEWIGGRNPVLEVLRSERDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGAHQGVAAQVAAY
QYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRAVGLTQTVAKASTGAMEYVPVVRVTN
MVRTMEELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY
EVYRKRFPLEK

Sequences:

>Translated_251_residues
MEQENEQEWIGGRNPVLEVLRSERDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGAHQGVAAQVAAY
QYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRAVGLTQTVAKASTGAMEYVPVVRVTN
MVRTMEELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY
EVYRKRFPLEK
>Mature_251_residues
MEQENEQEWIGGRNPVLEVLRSERDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGAHQGVAAQVAAY
QYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRAVGLTQTVAKASTGAMEYVPVVRVTN
MVRTMEELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY
EVYRKRFPLEK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=264, Percent_Identity=28.4090909090909, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1790623, Length=246, Percent_Identity=39.0243902439024, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1790083, Length=169, Percent_Identity=30.1775147928994, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788935, Length=176, Percent_Identity=23.8636363636364, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555908, Length=259, Percent_Identity=27.027027027027, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324775, Length=285, Percent_Identity=25.9649122807018, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28077; Mature: 28077

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQENEQEWIGGRNPVLEVLRSERDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQ
CCCCCCHHHCCCCCHHHHHHHCCCHHEEHHHHCCCCCCHHHHHHHHHHHCCEEEEECCHH
KIEKVVSGAHQGVAAQVAAYQYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
DSVGAHGIIIPKRRAVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTDA
HHCCCCEEEECCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
KGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY
CCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCEEECHHHHHHHHHHH
EVYRKRFPLEK
HHHHHHCCCCC
>Mature Secondary Structure
MEQENEQEWIGGRNPVLEVLRSERDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQ
CCCCCCHHHCCCCCHHHHHHHCCCHHEEHHHHCCCCCCHHHHHHHHHHHCCEEEEECCHH
KIEKVVSGAHQGVAAQVAAYQYAELDDLFAAAEAKDEMPFFIILDELEDPHNLGSIMRTA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHH
DSVGAHGIIIPKRRAVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTDA
HHCCCCEEEECCCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
KGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY
CCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHCCEEEECCCCCCEEECHHHHHHHHHHH
EVYRKRFPLEK
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]