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The map label for this gene is essB [H]

Identifier: 116871473

GI number: 116871473

Start: 51212

End: 52408

Strand: Direct

Name: essB [H]

Synonym: lwe0051

Alternate gene names: 116871473

Gene position: 51212-52408 (Clockwise)

Preceding gene: 116871472

Following gene: 116871474

Centisome position: 1.82

GC content: 34.09

Gene sequence:

>1197_bases
ATGAATAAGACAACAGATATGGACGGAACTGCTTATGATTTTACGTATGAGGATTTAGCGTGGAGTATCACTTTTCCTAA
ATCAAAAACCCATGCGAAAGAGTTAGCTCAATTAGAACTATTAGAGAAACCCGCGACTCATTTTGTGCCGGCAACAATTT
CAAGTGATAGCGATTCTTACATGATTTCATATGAGATTGATAAACATACATATGGATTTGAACAAATTCGCAAGATGGAA
CGGGAAGATAAACTGCGTGCTTTGCGGAATATAGCAGATTTAAGTGAACTATTAAATACGCGCTATACTTTTTTCTTGCA
TCCTGATAATTTGATTTTTGATATCAATTTAGTGCCTAGAATTGTTCATCGTGGAATTAAAAATATATTACCTCCATATG
AACTGACTGAAGAAACGTTCTTAAAGCAATACCAATGTTTCGCTATTGCCATGTTTTCTAAAAAATTCACTTTTGAAAAT
TTATATAATGGCTCCCTTTCTAGTGCAAGAGGAACTCAATTCGAAAAAAACATTTTAGATGCAAAAACGGTACAAGAAGT
TGCTGCGGTTTTAGAAGAAGCGTATATAAAAGAAAATAAATCTATGCAAAAGAATATGGCTCGCGTTCCTAAGAAAAAAT
ACGGGGCATTTCGTGGTCTTGCAGTTGGATTTATCATTGTAGCCATTTTACTTGCGATTCCAGTGAGCTATTTTGCTTTT
GTCAAAGTGCCGCTTCAAGACGATTTATTAACTGCGAACGAACAGTTTCTTAAGACCGACTACGATAAAGTAATCACCGG
ACTAGAAAAAGTGGACCCTGAAAAAATGCCGCAATCTGTTCAATATGAACTAGCATACTCCTATGTAAACGGCGAAAAAA
TGAGTGATAAAAAGAAAGAAAATATTATGAATACGATTAGTTTGAAATCGGACCCTAAAAACTTACTTTATTGGATTTAT
AATGGTCGCGGAGAATTCAGTGAATCGCTTGATATTGCTAAACTTTTAGATGACCCGACACTTGCAATGTATAGTTTAAC
AAAACAAATTGAACAAGTTCAAAGCGACACCAAACTTAGTGGTGAAGAAAAAGTAGAAAAACTAAAAACGTTAGAAGATA
GCTTAAAAGCATATGATGACAAAATAAATGAACAAACAAAAGAAACAGATGAGTCAACAAATACAGAAGCAAAATAA

Upstream 100 bases:

>100_bases
TAAAGCAATTTTGTTAAGCGACGATGATAAATTAACTAATTTTCAAATTGCTGATGGCGATATTTTAGAAATTTTATAGA
AAAAAAGGAGAATGAAAACG

Downstream 100 bases:

>100_bases
GGGAGAATGACCATGAATAGAGATGCTTTATTAATTGTTAGTAACGGGCAGCAATGTCATAAACACCATTTGTCCCCTGA
AAAAGTCGTGACAATCGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNKTTDMDGTAYDFTYEDLAWSITFPKSKTHAKELAQLELLEKPATHFVPATISSDSDSYMISYEIDKHTYGFEQIRKME
REDKLRALRNIADLSELLNTRYTFFLHPDNLIFDINLVPRIVHRGIKNILPPYELTEETFLKQYQCFAIAMFSKKFTFEN
LYNGSLSSARGTQFEKNILDAKTVQEVAAVLEEAYIKENKSMQKNMARVPKKKYGAFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQDDLLTANEQFLKTDYDKVITGLEKVDPEKMPQSVQYELAYSYVNGEKMSDKKKENIMNTISLKSDPKNLLYWIY
NGRGEFSESLDIAKLLDDPTLAMYSLTKQIEQVQSDTKLSGEEKVEKLKTLEDSLKAYDDKINEQTKETDESTNTEAK

Sequences:

>Translated_398_residues
MNKTTDMDGTAYDFTYEDLAWSITFPKSKTHAKELAQLELLEKPATHFVPATISSDSDSYMISYEIDKHTYGFEQIRKME
REDKLRALRNIADLSELLNTRYTFFLHPDNLIFDINLVPRIVHRGIKNILPPYELTEETFLKQYQCFAIAMFSKKFTFEN
LYNGSLSSARGTQFEKNILDAKTVQEVAAVLEEAYIKENKSMQKNMARVPKKKYGAFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQDDLLTANEQFLKTDYDKVITGLEKVDPEKMPQSVQYELAYSYVNGEKMSDKKKENIMNTISLKSDPKNLLYWIY
NGRGEFSESLDIAKLLDDPTLAMYSLTKQIEQVQSDTKLSGEEKVEKLKTLEDSLKAYDDKINEQTKETDESTNTEAK
>Mature_398_residues
MNKTTDMDGTAYDFTYEDLAWSITFPKSKTHAKELAQLELLEKPATHFVPATISSDSDSYMISYEIDKHTYGFEQIRKME
REDKLRALRNIADLSELLNTRYTFFLHPDNLIFDINLVPRIVHRGIKNILPPYELTEETFLKQYQCFAIAMFSKKFTFEN
LYNGSLSSARGTQFEKNILDAKTVQEVAAVLEEAYIKENKSMQKNMARVPKKKYGAFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQDDLLTANEQFLKTDYDKVITGLEKVDPEKMPQSVQYELAYSYVNGEKMSDKKKENIMNTISLKSDPKNLLYWIY
NGRGEFSESLDIAKLLDDPTLAMYSLTKQIEQVQSDTKLSGEEKVEKLKTLEDSLKAYDDKINEQTKETDESTNTEAK

Specific function: Required for secretion of esxA and esxB [H]

COG id: COG4499

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the essB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018778 [H]

Pfam domain/function: PF10140 essB [H]

EC number: NA

Molecular weight: Translated: 45741; Mature: 45741

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTTDMDGTAYDFTYEDLAWSITFPKSKTHAKELAQLELLEKPATHFVPATISSDSDSY
CCCCCCCCCCEEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHCCCHHEECEEECCCCCCE
MISYEIDKHTYGFEQIRKMEREDKLRALRNIADLSELLNTRYTFFLHPDNLIFDINLVPR
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHH
IVHRGIKNILPPYELTEETFLKQYQCFAIAMFSKKFTFENLYNGSLSSARGTQFEKNILD
HHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AKTVQEVAAVLEEAYIKENKSMQKNMARVPKKKYGAFRGLAVGFIIVAILLAIPVSYFAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVPLQDDLLTANEQFLKTDYDKVITGLEKVDPEKMPQSVQYELAYSYVNGEKMSDKKKE
EECCCCCCHHHCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHEECCCCCCCHHHHH
NIMNTISLKSDPKNLLYWIYNGRGEFSESLDIAKLLDDPTLAMYSLTKQIEQVQSDTKLS
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GEEKVEKLKTLEDSLKAYDDKINEQTKETDESTNTEAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNKTTDMDGTAYDFTYEDLAWSITFPKSKTHAKELAQLELLEKPATHFVPATISSDSDSY
CCCCCCCCCCEEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHCCCHHEECEEECCCCCCE
MISYEIDKHTYGFEQIRKMEREDKLRALRNIADLSELLNTRYTFFLHPDNLIFDINLVPR
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECHHHHH
IVHRGIKNILPPYELTEETFLKQYQCFAIAMFSKKFTFENLYNGSLSSARGTQFEKNILD
HHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AKTVQEVAAVLEEAYIKENKSMQKNMARVPKKKYGAFRGLAVGFIIVAILLAIPVSYFAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVPLQDDLLTANEQFLKTDYDKVITGLEKVDPEKMPQSVQYELAYSYVNGEKMSDKKKE
EECCCCCCHHHCCHHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHEECCCCCCCHHHHH
NIMNTISLKSDPKNLLYWIYNGRGEFSESLDIAKLLDDPTLAMYSLTKQIEQVQSDTKLS
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
GEEKVEKLKTLEDSLKAYDDKINEQTKETDESTNTEAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA