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The map label for this gene is agrA [H]

Identifier: 116871464

GI number: 116871464

Start: 40160

End: 40888

Strand: Direct

Name: agrA [H]

Synonym: lwe0042

Alternate gene names: 116871464

Gene position: 40160-40888 (Clockwise)

Preceding gene: 116871463

Following gene: 116871465

Centisome position: 1.43

GC content: 32.1

Gene sequence:

>729_bases
ATGCTACCGGTTTTTATTTGTGAAGATAACAAAATGCAGCGAGAAAGGTTAACAAAATATATTGAAGACTATATAATGGT
CGAACATTTTGATATGAAGTTAGAGCTTTCGACGGGAGATCCATTTGAGTTAGTGTCACGAATGCCTAGACATCAAGGTA
TGGGATTATATTTTTTAGATATTGATTTGGGGCAGCCGGACATGAATGGTTTTGAATTAGCTCAAGAAATTCGAAAATTT
GATCCACGTGGGTTTATTATTTTCATTACAACACATGCAGAACTAAGTTATATGACTTTTACGTACAAGGTGGAAGCGCT
TGATTACATTATCAAGGACGATATTGATATGTTGCATGAACGAGTTTTAGCTTGTATGAAGCAAGCAGAGGAACGAATTT
CAAATGATCAAGATATGCAGAAATACTTTACGTTTAAAGTTTCAGATAAGAAGATTATTCATGAACTTCTGGATGATATT
TTGTTTTTTGAGACAGCGCCAACTATCCATAAAGTAATTTTACATGGCAAAAATCGACAAGTAGAATTTTATGGTAAGCT
AAAAAGTATTGAAAAAATGTTGGATGAATCGTTTTATAGATGTCACCGCTCATATATTGTAAATAAGAAAAATATTCATG
AGTTAGATACGGCAAAAGGTGTTGTAAAAATGTCTAATGGTGAGAATTGTTATGCTTCGTCGAAATTAATTAAAAGTTTA
AGTTTATAA

Upstream 100 bases:

>100_bases
GATTATGAAGAAATATTCGCATGTTGCCTTAGATACAAAAGTGACTAATAGAGAAGTTATTCAAGAACTAGAAATTATGT
AGAAGAATGGGGATGAATTT

Downstream 100 bases:

>100_bases
AAGTGGCCTTTTGGGTCGCTTTTTTTGTACAAAAGTTAGTTTGGATTTGAAGAAACGCGGAATTATAGGTAAAATAATAG
TGGTGAATTGTTAGTTAAGT

Product: 2-components response regulator protein, AlgR/VirR/ComE type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLPVFICEDNKMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPRHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDMLHERVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKSIEKMLDESFYRCHRSYIVNKKNIHELDTAKGVVKMSNGENCYASSKLIKSL
SL

Sequences:

>Translated_242_residues
MLPVFICEDNKMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPRHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDMLHERVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKSIEKMLDESFYRCHRSYIVNKKNIHELDTAKGVVKMSNGENCYASSKLIKSL
SL
>Mature_242_residues
MLPVFICEDNKMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPRHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDMLHERVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKSIEKMLDESFYRCHRSYIVNKKNIHELDTAKGVVKMSNGENCYASSKLIKSL
SL

Specific function: Required for high-level post-exponential phase expression of a series of secreted proteins [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=226, Percent_Identity=26.1061946902655, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28553; Mature: 28553

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVFICEDNKMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPRHQGMGLYFLD
CCEEEEECCCCHHHHHHHHHHHHHHHHEEECEEEEECCCCHHHHHHCCHHHCCCEEEEEE
IDLGQPDMNGFELAQEIRKFDPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDMLHE
EECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHH
RVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDILFFETAPTIHKVILHGKNRQ
HHHHHHHHHHHHHCCCHHHHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VEFYGKLKSIEKMLDESFYRCHRSYIVNKKNIHELDTAKGVVKMSNGENCYASSKLIKSL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHH
SL
CC
>Mature Secondary Structure
MLPVFICEDNKMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPRHQGMGLYFLD
CCEEEEECCCCHHHHHHHHHHHHHHHHEEECEEEEECCCCHHHHHHCCHHHCCCEEEEEE
IDLGQPDMNGFELAQEIRKFDPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDMLHE
EECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHH
RVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDILFFETAPTIHKVILHGKNRQ
HHHHHHHHHHHHHCCCHHHHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VEFYGKLKSIEKMLDESFYRCHRSYIVNKKNIHELDTAKGVVKMSNGENCYASSKLIKSL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCCCCHHHHHHHHHH
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA