Click here to switch to the map view.

The map label for this gene is mhpA [H]

Identifier: 116696493

GI number: 116696493

Start: 2886266

End: 2887948

Strand: Direct

Name: mhpA [H]

Synonym: H16_B2557

Alternate gene names: 116696493

Gene position: 2886266-2887948 (Clockwise)

Preceding gene: 116696489

Following gene: 116696494

Centisome position: 99.1

GC content: 70.17

Gene sequence:

>1683_bases
ATGCCAGACTCCACCGCACCCCACGCCGCAGTGCCGCCGGCACCGCCGCCCTCGTCATCGCGCCCATGGCCGCAGCGCGT
GCCGGTACTGATTGCCGGCGGCGGCCCGGTCGGCCTGACGCTGGCCGCGCTGCTGGCGCGCCAGGGCATAGCCGCGCTGG
TGGTGGAAGCCGACGACGGCTACTGCGCCGGCAGCCGGGCCATCTGCATGGCGCGGCGTTCGCTGGAGATCCTCGGCTGG
GTGGGCGCAGACCGCGCCACCGTCGAAACCGGCCTGCCGTGGGTGGGCGGGCGTAGCTACTACCGCGATGCCGAGGTGCT
GCATTTCCGCATGCCCAGCGAGGCCGGCGAGCGCTTCGCCCCGATGGTCAATATCCAGCAGTACTACCTGGAAGCCTTCG
CCCACGACGCCGCGCTGCGCGGCGCTGCGCCAGCGGATGTGCGCTTCGGCGCGCGCGTGCAGGCGGTGCGCCAGCACGGC
AGCGGCGTCGTGGCCGAGATCCAGACAGGCGCAGGCGTGGTGCAGGTCGGCGCGCAATGGCTGGTGGCCTGCGACGGCGG
GCGCAGCACCGTGCGCGAGCAACTGGGGCTGCGCATGAAGGGCACCCAGTACGAAGGCCGCTACGTGATCGTCGATATCG
TGCAGAAGACGCGGCGCGAGGTGGAGCGGCTGGCCTGGTTCGACCCGCCTTCCAACCCCGGATCGACCATCCTGATGCAC
CGCCAGCCTGACGACGTCTGGCGCATCGACTACCAGATCCGCGACGACGAAGACCCTGACGAAGCCGTCAAGCCGGAGAA
CGTGCTGCCGCGCGTGCAGAGCCACCTCGACATGATCGGCGAGACCGAGCCGTGGCGGCCGTTGTGGATCTCCATCTACA
ACGCCAAGTGCCTGACCTTGCAGGACTACCGCCACGGCCGCGTGCTGTTTGCCGGCGACGCCGCGCACCTGGTGCCGATC
TTTGGCGTGCGCGGGCTCAACTCCGGGCTGGACGATGCCGGCAACCTGGCCTGGAAGCTGGCGTGGGTGCTGCGCGGCCA
GGCGCCCGAAAGCCTGCTCGATTCCTATTCGACCGAACGCGTGCATGCCACGCGGCAGAACATCGCCTACGGCGCCAAGA
GCACCGAGTTCATGGCACCGCCCGACTTTGCCTTCCGGCTGATGCGCGAGGCCACGCTGCGTCTGGCGCAGCATGAGCCC
GCGGTGCGGTCACTGATCAATCCGCGGCAGTCGGCACCGATTGCCTATACGGATTCGGCGCTGAACGGTCCCAGCGACTT
TGGCGACGACTGTCCTGGCGCCGCGCCCGGCCTGCCCGCGCCGGAAATGCGCGTGGCAGGCCCCGACGAGGTCGTGCACC
TCACGCAATGCTTCGGGCAACGGTTCACGTTGCTGTACTTCAGCGATGCGCCCACGCTGCCCGAGCCACTGGCCGCGTTC
GCGCATGCGCATCCGGACGCCATGCAGACACACGTGGTGGTCACCGGCGGCAACGTGGCCGGCGCCACGGCGCTGGCCGA
CGTCGCCGGCCAGGCCCACGCCCGCTACGGCGCACGACCCGGCACGCTCTACCTGATCCGCCCCGATGGCTATGTCCTGG
CACGCTGGCGCGAACCGTCATGGGACGCCGTGCGCGCCACCCTTGCCCCCCTGATGCAAACCGGAGCCCGCCATGCAAGC
TGA

Upstream 100 bases:

>100_bases
ATGGCCGTTTCCCGGCCGGGTTAACACTAGTTTCGTGCGCAACCATCTAGTCGATATAGTTGCGCACACAACTACATCGC
AGAGACACTACGACCCCACC

Downstream 100 bases:

>100_bases
AGACCTCGACCTCGCCTACACCCATCTGTGCGAGGCCATGGGCCGTGCCGGCGAAGCGCGCACCCCGCTGCTATTGGCAA
TGGTGTGCCTGGGCCTGATG

Product: FAD-dependent oxidoreductase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase; Flavin-type monooxygenase [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MPDSTAPHAAVPPAPPPSSSRPWPQRVPVLIAGGGPVGLTLAALLARQGIAALVVEADDGYCAGSRAICMARRSLEILGW
VGADRATVETGLPWVGGRSYYRDAEVLHFRMPSEAGERFAPMVNIQQYYLEAFAHDAALRGAAPADVRFGARVQAVRQHG
SGVVAEIQTGAGVVQVGAQWLVACDGGRSTVREQLGLRMKGTQYEGRYVIVDIVQKTRREVERLAWFDPPSNPGSTILMH
RQPDDVWRIDYQIRDDEDPDEAVKPENVLPRVQSHLDMIGETEPWRPLWISIYNAKCLTLQDYRHGRVLFAGDAAHLVPI
FGVRGLNSGLDDAGNLAWKLAWVLRGQAPESLLDSYSTERVHATRQNIAYGAKSTEFMAPPDFAFRLMREATLRLAQHEP
AVRSLINPRQSAPIAYTDSALNGPSDFGDDCPGAAPGLPAPEMRVAGPDEVVHLTQCFGQRFTLLYFSDAPTLPEPLAAF
AHAHPDAMQTHVVVTGGNVAGATALADVAGQAHARYGARPGTLYLIRPDGYVLARWREPSWDAVRATLAPLMQTGARHAS

Sequences:

>Translated_560_residues
MPDSTAPHAAVPPAPPPSSSRPWPQRVPVLIAGGGPVGLTLAALLARQGIAALVVEADDGYCAGSRAICMARRSLEILGW
VGADRATVETGLPWVGGRSYYRDAEVLHFRMPSEAGERFAPMVNIQQYYLEAFAHDAALRGAAPADVRFGARVQAVRQHG
SGVVAEIQTGAGVVQVGAQWLVACDGGRSTVREQLGLRMKGTQYEGRYVIVDIVQKTRREVERLAWFDPPSNPGSTILMH
RQPDDVWRIDYQIRDDEDPDEAVKPENVLPRVQSHLDMIGETEPWRPLWISIYNAKCLTLQDYRHGRVLFAGDAAHLVPI
FGVRGLNSGLDDAGNLAWKLAWVLRGQAPESLLDSYSTERVHATRQNIAYGAKSTEFMAPPDFAFRLMREATLRLAQHEP
AVRSLINPRQSAPIAYTDSALNGPSDFGDDCPGAAPGLPAPEMRVAGPDEVVHLTQCFGQRFTLLYFSDAPTLPEPLAAF
AHAHPDAMQTHVVVTGGNVAGATALADVAGQAHARYGARPGTLYLIRPDGYVLARWREPSWDAVRATLAPLMQTGARHAS
>Mature_559_residues
PDSTAPHAAVPPAPPPSSSRPWPQRVPVLIAGGGPVGLTLAALLARQGIAALVVEADDGYCAGSRAICMARRSLEILGWV
GADRATVETGLPWVGGRSYYRDAEVLHFRMPSEAGERFAPMVNIQQYYLEAFAHDAALRGAAPADVRFGARVQAVRQHGS
GVVAEIQTGAGVVQVGAQWLVACDGGRSTVREQLGLRMKGTQYEGRYVIVDIVQKTRREVERLAWFDPPSNPGSTILMHR
QPDDVWRIDYQIRDDEDPDEAVKPENVLPRVQSHLDMIGETEPWRPLWISIYNAKCLTLQDYRHGRVLFAGDAAHLVPIF
GVRGLNSGLDDAGNLAWKLAWVLRGQAPESLLDSYSTERVHATRQNIAYGAKSTEFMAPPDFAFRLMREATLRLAQHEPA
VRSLINPRQSAPIAYTDSALNGPSDFGDDCPGAAPGLPAPEMRVAGPDEVVHLTQCFGQRFTLLYFSDAPTLPEPLAAFA
HAHPDAMQTHVVVTGGNVAGATALADVAGQAHARYGARPGTLYLIRPDGYVLARWREPSWDAVRATLAPLMQTGARHAS

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=531, Percent_Identity=27.4952919020716, Blast_Score=141, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 60820; Mature: 60688

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSTAPHAAVPPAPPPSSSRPWPQRVPVLIAGGGPVGLTLAALLARQGIAALVVEADDG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCCC
YCAGSRAICMARRSLEILGWVGADRATVETGLPWVGGRSYYRDAEVLHFRMPSEAGERFA
CCCCCHHHHHHHHCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHC
PMVNIQQYYLEAFAHDAALRGAAPADVRFGARVQAVRQHGSGVVAEIQTGAGVVQVGAQW
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEECCEE
LVACDGGRSTVREQLGLRMKGTQYEGRYVIVDIVQKTRREVERLAWFDPPSNPGSTILMH
EEEECCCHHHHHHHHCCEECCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
RQPDDVWRIDYQIRDDEDPDEAVKPENVLPRVQSHLDMIGETEPWRPLWISIYNAKCLTL
CCCCCEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEE
QDYRHGRVLFAGDAAHLVPIFGVRGLNSGLDDAGNLAWKLAWVLRGQAPESLLDSYSTER
ECCCCCEEEEECCCHHEEHHHCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHCCCHHH
VHATRQNIAYGAKSTEFMAPPDFAFRLMREATLRLAQHEPAVRSLINPRQSAPIAYTDSA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEECCC
LNGPSDFGDDCPGAAPGLPAPEMRVAGPDEVVHLTQCFGQRFTLLYFSDAPTLPEPLAAF
CCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
AHAHPDAMQTHVVVTGGNVAGATALADVAGQAHARYGARPGTLYLIRPDGYVLARWREPS
HHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCC
WDAVRATLAPLMQTGARHAS
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PDSTAPHAAVPPAPPPSSSRPWPQRVPVLIAGGGPVGLTLAALLARQGIAALVVEADDG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEEECCCC
YCAGSRAICMARRSLEILGWVGADRATVETGLPWVGGRSYYRDAEVLHFRMPSEAGERFA
CCCCCHHHHHHHHCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHC
PMVNIQQYYLEAFAHDAALRGAAPADVRFGARVQAVRQHGSGVVAEIQTGAGVVQVGAQW
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEECCEE
LVACDGGRSTVREQLGLRMKGTQYEGRYVIVDIVQKTRREVERLAWFDPPSNPGSTILMH
EEEECCCHHHHHHHHCCEECCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
RQPDDVWRIDYQIRDDEDPDEAVKPENVLPRVQSHLDMIGETEPWRPLWISIYNAKCLTL
CCCCCEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEE
QDYRHGRVLFAGDAAHLVPIFGVRGLNSGLDDAGNLAWKLAWVLRGQAPESLLDSYSTER
ECCCCCEEEEECCCHHEEHHHCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHCCCHHH
VHATRQNIAYGAKSTEFMAPPDFAFRLMREATLRLAQHEPAVRSLINPRQSAPIAYTDSA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCEEEECCC
LNGPSDFGDDCPGAAPGLPAPEMRVAGPDEVVHLTQCFGQRFTLLYFSDAPTLPEPLAAF
CCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
AHAHPDAMQTHVVVTGGNVAGATALADVAGQAHARYGARPGTLYLIRPDGYVLARWREPS
HHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEECCCC
WDAVRATLAPLMQTGARHAS
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA