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The map label for this gene is exuR [H]

Identifier: 116696392

GI number: 116696392

Start: 2777460

End: 2778158

Strand: Direct

Name: exuR [H]

Synonym: H16_B2456

Alternate gene names: 116696392

Gene position: 2777460-2778158 (Clockwise)

Preceding gene: 116696389

Following gene: 116696395

Centisome position: 95.36

GC content: 58.8

Gene sequence:

>699_bases
TTGCGCACGCCTGTCACGCAGCACGCCTTGGAGCGCATGCAGACATCCATCTACAGCGGCGAATGGGCGGCGGACAGCCA
GATCCCCTCACAGCGTGAGTTGGCTGAGCTGCTCGGCGTAAGCCGCTCTTCCTTGCGCGAGGCAATTTCCTCGCTGGAGG
GAATGGGGCTGGTGCGGGTAGAGCCCGGCAGAGGCGTGTTTGTAGCATCGCTCGAGCAGCAGGCTGCCGTCGGCAGAAAC
TCTGAAGTTCATCAGATCGACCATACACCGAGTGAACTTTATGAGGCACGCCTGTTGATGGAAGGTTGGGCCGCCGCCCT
CGCATCCATCCATATCACCGATGACGACATCGCCGCCCTACGAAAACTGCTGGGGGAGATGGAAATCACGGTAAAGGACC
ACGATGTCACACGGCTGAACCAGCTGGATTTCGAGTTTCACTCGCTGATAGCTTCTTGCTGCGGCAATCGCCTGATTCGT
GCACTACTTGCTCCGATTTTCTCGGAGGAAGAAATGAGCGCCCCGCGCCTTTCCGACACGGCATTCCTGAGCAGCCGCGT
CAAAGAGCACAAGGAAATCGTGGAAGCCTTGGCAACGCGCAACCCTGGCCTCGCTCAAATGGCCATGCGTAACCATGTCC
TGCGCAGCGCAAAGCGTGTCCAGGTAGAGCTGCCTGAGCACGTACATCAGCTGCCTTGA

Upstream 100 bases:

>100_bases
AGTGTCACCTACACAGACTATGAAAGCGACTTCCGCTGCATTGGCACCCAAGGCGCCGCTGACTGCTCCCGCGCCACCAG
GGCGTCGGCCACCTATCGCA

Downstream 100 bases:

>100_bases
TGCACCACAACTGCATGCCGTTGGCGGGACCGTCGCCTGCCAACGGCCGCAGCATGCGTCAGAAGGTGAAATCGCGATTC
ACGTTCTTGTAGAGCAGGTA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRTPVTQHALERMQTSIYSGEWAADSQIPSQRELAELLGVSRSSLREAISSLEGMGLVRVEPGRGVFVASLEQQAAVGRN
SEVHQIDHTPSELYEARLLMEGWAAALASIHITDDDIAALRKLLGEMEITVKDHDVTRLNQLDFEFHSLIASCCGNRLIR
ALLAPIFSEEEMSAPRLSDTAFLSSRVKEHKEIVEALATRNPGLAQMAMRNHVLRSAKRVQVELPEHVHQLP

Sequences:

>Translated_232_residues
MRTPVTQHALERMQTSIYSGEWAADSQIPSQRELAELLGVSRSSLREAISSLEGMGLVRVEPGRGVFVASLEQQAAVGRN
SEVHQIDHTPSELYEARLLMEGWAAALASIHITDDDIAALRKLLGEMEITVKDHDVTRLNQLDFEFHSLIASCCGNRLIR
ALLAPIFSEEEMSAPRLSDTAFLSSRVKEHKEIVEALATRNPGLAQMAMRNHVLRSAKRVQVELPEHVHQLP
>Mature_232_residues
MRTPVTQHALERMQTSIYSGEWAADSQIPSQRELAELLGVSRSSLREAISSLEGMGLVRVEPGRGVFVASLEQQAAVGRN
SEVHQIDHTPSELYEARLLMEGWAAALASIHITDDDIAALRKLLGEMEITVKDHDVTRLNQLDFEFHSLIASCCGNRLIR
ALLAPIFSEEEMSAPRLSDTAFLSSRVKEHKEIVEALATRNPGLAQMAMRNHVLRSAKRVQVELPEHVHQLP

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789353, Length=234, Percent_Identity=28.6324786324786, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87082208, Length=209, Percent_Identity=27.7511961722488, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789621, Length=219, Percent_Identity=25.5707762557078, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=25.9433962264151, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25804; Mature: 25804

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPVTQHALERMQTSIYSGEWAADSQIPSQRELAELLGVSRSSLREAISSLEGMGLVRV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEE
EPGRGVFVASLEQQAAVGRNSEVHQIDHTPSELYEARLLMEGWAAALASIHITDDDIAAL
CCCCCEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RKLLGEMEITVKDHDVTRLNQLDFEFHSLIASCCGNRLIRALLAPIFSEEEMSAPRLSDT
HHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHH
AFLSSRVKEHKEIVEALATRNPGLAQMAMRNHVLRSAKRVQVELPEHVHQLP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECHHHHHCCC
>Mature Secondary Structure
MRTPVTQHALERMQTSIYSGEWAADSQIPSQRELAELLGVSRSSLREAISSLEGMGLVRV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCEEEE
EPGRGVFVASLEQQAAVGRNSEVHQIDHTPSELYEARLLMEGWAAALASIHITDDDIAAL
CCCCCEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RKLLGEMEITVKDHDVTRLNQLDFEFHSLIASCCGNRLIRALLAPIFSEEEMSAPRLSDT
HHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHH
AFLSSRVKEHKEIVEALATRNPGLAQMAMRNHVLRSAKRVQVELPEHVHQLP
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA