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The map label for this gene is degU [H]

Identifier: 116696371

GI number: 116696371

Start: 2750276

End: 2750995

Strand: Direct

Name: degU [H]

Synonym: H16_B2435

Alternate gene names: 116696371

Gene position: 2750276-2750995 (Clockwise)

Preceding gene: 116696347

Following gene: 116696372

Centisome position: 94.43

GC content: 65.28

Gene sequence:

>720_bases
ATGCCTTTCTCCATGCCAACGAACGCGACGCTCTCCGATAGCCGCCGAAACGTCATGCGTGGCCAACTGCTGCTGGTCGG
GCACGAGAGCCCGATGCTGACGCGCCTTTGCGGGATCCTCACCGTGCTCGACTACGCGGCCGGCGCGCTCTCGTTCGCGG
GCACCATCGCGCAGGCCTGCGCGCTGGTGGATCAGGGTCCGTTCGACATGGCGCTGGTCGACACCAGCCTGCCCGATGGC
AGTGGCATCGAGCTGATCCGGTGCCTGCGCGAGCGTGCCCCGGATCTGCCCATCGTCGTGATTGCATCACCGGGCACGGA
CACGGAAATCGTCGGCGCGCTGATCGCCGGCGCCACCGGCTACCTGCTCAAGGAGCGCGACGACATCGAGCTGACGGTGT
GCCTGCGGGGCGCGCTGCGCGGTGGCACGCCGATCGATCCGTCCATTGCCAAGCGGCTACTCACGACATTGGTACCCAAG
GCCGCACCCGCCGAGACCAGGCTTTCACCGACGGGAAGCGTAAAGCCGCTGCTCAGCGCACGCGAGACCGAGATCCTCGT
CTTCATCAACAAGGGGTCGACCAACCGCGAGATCGCCGACGCACTGTCACTGTCGCGGCTGACCATCGAGTCGCACGTCA
AGAACATCTATAAGAAGCTGGCGGTCAAGACGCGCACGCAGGCTATCTTTGAAGCGCGTGCGTACGGCGTGCTGAACTGA

Upstream 100 bases:

>100_bases
ATTGCATCACTGCGGGTCCGATGGTGAAATCAGCGCCGCTGATCATCTGAACTGCACCCGACCGGGCATGCAGCTCGCAT
CCCTGGTCGCACCAGCCCCC

Downstream 100 bases:

>100_bases
GGCGCTAGCCCATCCCTGAGTTGGCGGCGCCGAAGCGGAGCGCCGTTCCTCGCTGCGCATGCTCGTGCCAACGGCATCTG
GTTCGATCGCGCCATGCTAT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MPFSMPTNATLSDSRRNVMRGQLLLVGHESPMLTRLCGILTVLDYAAGALSFAGTIAQACALVDQGPFDMALVDTSLPDG
SGIELIRCLRERAPDLPIVVIASPGTDTEIVGALIAGATGYLLKERDDIELTVCLRGALRGGTPIDPSIAKRLLTTLVPK
AAPAETRLSPTGSVKPLLSARETEILVFINKGSTNREIADALSLSRLTIESHVKNIYKKLAVKTRTQAIFEARAYGVLN

Sequences:

>Translated_239_residues
MPFSMPTNATLSDSRRNVMRGQLLLVGHESPMLTRLCGILTVLDYAAGALSFAGTIAQACALVDQGPFDMALVDTSLPDG
SGIELIRCLRERAPDLPIVVIASPGTDTEIVGALIAGATGYLLKERDDIELTVCLRGALRGGTPIDPSIAKRLLTTLVPK
AAPAETRLSPTGSVKPLLSARETEILVFINKGSTNREIADALSLSRLTIESHVKNIYKKLAVKTRTQAIFEARAYGVLN
>Mature_238_residues
PFSMPTNATLSDSRRNVMRGQLLLVGHESPMLTRLCGILTVLDYAAGALSFAGTIAQACALVDQGPFDMALVDTSLPDGS
GIELIRCLRERAPDLPIVVIASPGTDTEIVGALIAGATGYLLKERDDIELTVCLRGALRGGTPIDPSIAKRLLTTLVPKA
APAETRLSPTGSVKPLLSARETEILVFINKGSTNREIADALSLSRLTIESHVKNIYKKLAVKTRTQAIFEARAYGVLN

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=24.6376811594203, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1786747, Length=172, Percent_Identity=26.7441860465116, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25481; Mature: 25350

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSMPTNATLSDSRRNVMRGQLLLVGHESPMLTRLCGILTVLDYAAGALSFAGTIAQAC
CCCCCCCCCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDQGPFDMALVDTSLPDGSGIELIRCLRERAPDLPIVVIASPGTDTEIVGALIAGATG
HHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCC
YLLKERDDIELTVCLRGALRGGTPIDPSIAKRLLTTLVPKAAPAETRLSPTGSVKPLLSA
CEEECCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCC
RETEILVFINKGSTNREIADALSLSRLTIESHVKNIYKKLAVKTRTQAIFEARAYGVLN
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFSMPTNATLSDSRRNVMRGQLLLVGHESPMLTRLCGILTVLDYAAGALSFAGTIAQAC
CCCCCCCCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVDQGPFDMALVDTSLPDGSGIELIRCLRERAPDLPIVVIASPGTDTEIVGALIAGATG
HHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCC
YLLKERDDIELTVCLRGALRGGTPIDPSIAKRLLTTLVPKAAPAETRLSPTGSVKPLLSA
CEEECCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCC
RETEILVFINKGSTNREIADALSLSRLTIESHVKNIYKKLAVKTRTQAIFEARAYGVLN
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]