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The map label for this gene is fliD [H]

Identifier: 116696298

GI number: 116696298

Start: 2675068

End: 2676474

Strand: Direct

Name: fliD [H]

Synonym: H16_B2362

Alternate gene names: 116696298

Gene position: 2675068-2676474 (Clockwise)

Preceding gene: 116696297

Following gene: 116696299

Centisome position: 91.85

GC content: 62.05

Gene sequence:

>1407_bases
ATGGCAACGATCTCCTCCATCGGCATCGGTTCCAACCTGCAACTGAGCGACCTGCTGGACCAGCTGCAGAAGGCCGAGCA
GGCACCGCTTGACGCCATCAATGCGCAGGCCAAGAGCTACCAGACCAAGTTGTCGGCCTACAGTCAGGTGCAGAGCGTGC
TGGACGCCTACCAGGGCGCGGCGAAGAAGCTGTCCGATGCTGCCACCTTCGGCGCAGTAAAGGCCAGCATCGGCACCACG
GACGTGATGAACGTCACCACCGCTGCCAACGCCGTGCCTGGCAGCTACAGCATTACTGTCAACACGCTGGCCACCGCGCA
GTCGCTGGTGAGCAGCAACGTTGCCGACCAGAAGGCCGCGATCGGTGGCGGCGAGCTCGTGTTCGACTTCGGCGAAGCGC
TGGCCACCGGTGGCGCCGCCACTAGCACCAAGAAGGTCACCATCCCCGCGGATTCTTCGCTCGAAGGAATGCGCGATGCC
ATCAACAAGGCCAGCATCGGCGTGACGGCCAGCATCGTCAATGACGGCAGCGCCAGCCCTTACCGCCTGGTATTGACGTC
GGACAAGACCGGAACGCAAGCCACCATGCGGGTGTCGTCGACCGATGCGGCACTGAACAACGTGGTTGCGTTCGACCCGG
CCGCGGCGCCCGCCGCCAACAAGATGGAACAGAAGGTGCCGCCTGCCAATGCGACGCTGACGATCAACGGCATCGACGTG
GTCAGCCAGAGCAATTCAGTGGTGGACGCAGCGCAGGGCGTGACCATGAACCTTGTCAAGCCAGGCACGACATCGCTGGT
GGTGACCCGCGACAACGTCGCAATCAAGGCCGCCGTCCAGGCTTTTGTCACCGCCTACAACAACATTCAGAGTTCCGCCA
AGTCGCTGACGGCATTCGATACGAAGGCCGGTACGTCCGCGGCATTGACCGGCGACGGCACGCTGCGCTCGATCCAGTCC
AGCCTGCGTTCAATGCTGGGCGGTGCCATGGATGACGGCAACGGCGGCACGATCACGCTGATCGACGTCGGCATCTCGTT
CGACAAAGACGGCACGATGAAGCTGGACGACACCAAGCTGACCAAGGCGATAAACGAAGACCTGGGTGGCGTCACGTCCC
TGTTTTCCAGCACCACCGGCGACGGAGGCATCGGCAAGCGCGCCAGCACCTATATCGAGGGCCTGAGCAAGACCGATGGC
GCGCTGAAGGTGGCTCAGGATGGCATCACCAAGACGCTGAAGGACCTGGAAGACGACTATGACCGCGTCCAGGACCGCGT
TACTGCCACGGTGGCTCGATACAAGGCCCAGTTCACGCAACTGGACCTGGTGGTAGCGCAGATGAACCGTACCAGCAGCT
ACCTGACGCAACAGTTCAATGCGCTGAACAACAGCACCAAGAAGTAA

Upstream 100 bases:

>100_bases
AGAGGTGCTGCGCATTGCCCGCGCCATCGACAAGCTGCAGGGGTTGTTCATCAACCACGCGGCCTGAGCCCTGAATATCA
GTTGAAGACGAGACAATAAT

Downstream 100 bases:

>100_bases
CCGTCCCGCCGCACACCACAGCCTGAAGGAACCCAACCATGTTCGCCCGCGCATCCGCCAACGCCTACGCCCAGGTCGGC
GTCCAGACCGGCGCCATGAG

Product: flagellar hook-associated protein 2

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MATISSIGIGSNLQLSDLLDQLQKAEQAPLDAINAQAKSYQTKLSAYSQVQSVLDAYQGAAKKLSDAATFGAVKASIGTT
DVMNVTTAANAVPGSYSITVNTLATAQSLVSSNVADQKAAIGGGELVFDFGEALATGGAATSTKKVTIPADSSLEGMRDA
INKASIGVTASIVNDGSASPYRLVLTSDKTGTQATMRVSSTDAALNNVVAFDPAAAPAANKMEQKVPPANATLTINGIDV
VSQSNSVVDAAQGVTMNLVKPGTTSLVVTRDNVAIKAAVQAFVTAYNNIQSSAKSLTAFDTKAGTSAALTGDGTLRSIQS
SLRSMLGGAMDDGNGGTITLIDVGISFDKDGTMKLDDTKLTKAINEDLGGVTSLFSSTTGDGGIGKRASTYIEGLSKTDG
ALKVAQDGITKTLKDLEDDYDRVQDRVTATVARYKAQFTQLDLVVAQMNRTSSYLTQQFNALNNSTKK

Sequences:

>Translated_468_residues
MATISSIGIGSNLQLSDLLDQLQKAEQAPLDAINAQAKSYQTKLSAYSQVQSVLDAYQGAAKKLSDAATFGAVKASIGTT
DVMNVTTAANAVPGSYSITVNTLATAQSLVSSNVADQKAAIGGGELVFDFGEALATGGAATSTKKVTIPADSSLEGMRDA
INKASIGVTASIVNDGSASPYRLVLTSDKTGTQATMRVSSTDAALNNVVAFDPAAAPAANKMEQKVPPANATLTINGIDV
VSQSNSVVDAAQGVTMNLVKPGTTSLVVTRDNVAIKAAVQAFVTAYNNIQSSAKSLTAFDTKAGTSAALTGDGTLRSIQS
SLRSMLGGAMDDGNGGTITLIDVGISFDKDGTMKLDDTKLTKAINEDLGGVTSLFSSTTGDGGIGKRASTYIEGLSKTDG
ALKVAQDGITKTLKDLEDDYDRVQDRVTATVARYKAQFTQLDLVVAQMNRTSSYLTQQFNALNNSTKK
>Mature_467_residues
ATISSIGIGSNLQLSDLLDQLQKAEQAPLDAINAQAKSYQTKLSAYSQVQSVLDAYQGAAKKLSDAATFGAVKASIGTTD
VMNVTTAANAVPGSYSITVNTLATAQSLVSSNVADQKAAIGGGELVFDFGEALATGGAATSTKKVTIPADSSLEGMRDAI
NKASIGVTASIVNDGSASPYRLVLTSDKTGTQATMRVSSTDAALNNVVAFDPAAAPAANKMEQKVPPANATLTINGIDVV
SQSNSVVDAAQGVTMNLVKPGTTSLVVTRDNVAIKAAVQAFVTAYNNIQSSAKSLTAFDTKAGTSAALTGDGTLRSIQSS
LRSMLGGAMDDGNGGTITLIDVGISFDKDGTMKLDDTKLTKAINEDLGGVTSLFSSTTGDGGIGKRASTYIEGLSKTDGA
LKVAQDGITKTLKDLEDDYDRVQDRVTATVARYKAQFTQLDLVVAQMNRTSSYLTQQFNALNNSTKK

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=496, Percent_Identity=38.7096774193548, Blast_Score=253, Evalue=2e-68,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 48209; Mature: 48078

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATISSIGIGSNLQLSDLLDQLQKAEQAPLDAINAQAKSYQTKLSAYSQVQSVLDAYQGA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKLSDAATFGAVKASIGTTDVMNVTTAANAVPGSYSITVNTLATAQSLVSSNVADQKAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHC
IGGGELVFDFGEALATGGAATSTKKVTIPADSSLEGMRDAINKASIGVTASIVNDGSASP
CCCCCEEEEHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
YRLVLTSDKTGTQATMRVSSTDAALNNVVAFDPAAAPAANKMEQKVPPANATLTINGIDV
EEEEEECCCCCCEEEEEECCCHHHHHCEEEECCCCCCCHHHHHHCCCCCCCEEEEECEEE
VSQSNSVVDAAQGVTMNLVKPGTTSLVVTRDNVAIKAAVQAFVTAYNNIQSSAKSLTAFD
ECCCCCHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TKAGTSAALTGDGTLRSIQSSLRSMLGGAMDDGNGGTITLIDVGISFDKDGTMKLDDTKL
CCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCEEECHHHH
TKAINEDLGGVTSLFSSTTGDGGIGKRASTYIEGLSKTDGALKVAQDGITKTLKDLEDDY
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
DRVQDRVTATVARYKAQFTQLDLVVAQMNRTSSYLTQQFNALNNSTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ATISSIGIGSNLQLSDLLDQLQKAEQAPLDAINAQAKSYQTKLSAYSQVQSVLDAYQGA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKKLSDAATFGAVKASIGTTDVMNVTTAANAVPGSYSITVNTLATAQSLVSSNVADQKAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHCCCCHHHHC
IGGGELVFDFGEALATGGAATSTKKVTIPADSSLEGMRDAINKASIGVTASIVNDGSASP
CCCCCEEEEHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
YRLVLTSDKTGTQATMRVSSTDAALNNVVAFDPAAAPAANKMEQKVPPANATLTINGIDV
EEEEEECCCCCCEEEEEECCCHHHHHCEEEECCCCCCCHHHHHHCCCCCCCEEEEECEEE
VSQSNSVVDAAQGVTMNLVKPGTTSLVVTRDNVAIKAAVQAFVTAYNNIQSSAKSLTAFD
ECCCCCHHHHHCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TKAGTSAALTGDGTLRSIQSSLRSMLGGAMDDGNGGTITLIDVGISFDKDGTMKLDDTKL
CCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCEEECHHHH
TKAINEDLGGVTSLFSSTTGDGGIGKRASTYIEGLSKTDGALKVAQDGITKTLKDLEDDY
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
DRVQDRVTATVARYKAQFTQLDLVVAQMNRTSSYLTQQFNALNNSTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]