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The map label for this gene is evgS [H]

Identifier: 116696290

GI number: 116696290

Start: 2666432

End: 2668441

Strand: Direct

Name: evgS [H]

Synonym: H16_B2354

Alternate gene names: 116696290

Gene position: 2666432-2668441 (Clockwise)

Preceding gene: 116696289

Following gene: 116696291

Centisome position: 91.55

GC content: 71.79

Gene sequence:

>2010_bases
ATGACGCCGCATGCCGCCAACCCGGCCCCGCTGATCCTGAATGTCGATGACCGCGAGGGGCCGCGCTACGTCAAGAGTCG
CATCCTCCATCGCGGCGAGTATTCCGTGATCGAGGCCGCCACCGGCCATTCGGCGCTGTCGCTGGTGCGACAGCATGCGC
CGGTGCTGGTGCTGCTGGCCGCACGCCTGCCCGATATCAGCGGGCTGGAAGTCTGCCGGCTGCTCAAGGCCGATCCACAG
ACCGCGCACACGCTGGTGCTGCTGACCTCGCCAGGGCTGGCGCAATCGCGCCAGCGCGTAGAGGCGCTGAACTGCGGCGC
CGACGGCTACCTGGTCGAGCCTGCCGAGCCGGAAGAGGTGTTGTCGAGCATCCAGGCGCTGCTGCGGCTGCGCGGGGCAG
AGGACGCCTATCACCGCACCTCGCGGGCACTGCATGAGCATGAAGACATGTTCCGCCAGGTGGCCGAATCGCTGGCCGAC
GTGGTGTGGATCCTCGACCCGGCCGAGCCCCGCCTGCTGTTCGCCAGCCCCTCGCTCGCCACGTTGTGCGGCCATAAGCC
CGAGCAGCTGACGCAAGAGCCGCGCCGCTGCCTGGAGCGCGTGGCGCCGGCCGACCGTGCGCGCGTGGAAGCGGCGTTCG
CCAGCATGCTGGGCGACGGCAGGCTGGACATCGAGTTCCGCCTTGCGCGCCCGGACGGCGAGCTGCGCGATATCCGCGCG
CGCGCGTTCCCGGTACGCGGCGCGGAAGGCCAGCCGGGCGACGACCGCACGCCGCCGTTGCGCATTGCCGGCACCTGCCA
GGACGTGACGCTGCAAAACCGTGCCGGCCGCGCGCTGCATGACGAGGAACGGCGCAAGGACCAGTTCCTGGCGATGCTGG
CGCATGAACTGCGCAATCCGCTGGCGCCGCTGCGCAGCGCCGCGGACCTGTTGCAGCAGCTCTCGCCCTCGCGCGAGGAC
ATGTTCCGCGCGCGCGACATCATCGGCCGGCAGCTGCACCACCTGACCCGGCTGGTGGACGAGCTGCTCGACATCTCGCG
CTTCAACCAGGGCCGCATCACGCTGCGCGAGGACCTGGTGGAACTGCGCACCGCGCTCAATACCGCGGTGGAAGCCGTGC
GCCCCACGATGGACGCCTGCGGCCATACGCTGCGCCTGTCGCTGCCCGAGCAGCCCCTGCCGGTACGTGGCGACCTGGTG
CGCCTGGCGCAGATCTTCAGCAACCTGCTGCAGAACGCCGCGGCCTACACGCCCGCCGGCGGCCAGATCGTCGTCGATGC
CAGTCTCGAGGACGGCGCGGCGAACACCGCGCCCGATGCCGCGTCCGGCGCCCGCGTCACCGTGCGCGTGCGCGACAACG
GCGCCGGCCTGTCCGAGGCACTGCAGCGGCAGCTGTTCGATCCGCTGGCCGCGCGCGACGACGGCACCCAGCCCGAACCG
CCGCGCAGCGCGATCCAGCAGGACGGTCCCGGCATCGGCCTGACGCTGGTGCAAAAGCTGGTGCGGCTACATGGCGGCAC
CATCCGCGCCGACAGCCCCGGCCCCGGACAGGGCAGCACCTTCACCGTGACGCTGCCGGTAGAGCCGTGGCAGAAGTGGC
ACCCAGGCTCCGGCCGCACCGCGCCGCACCGCGGCGTGCCGCGCCGGATCATGGTGGTGGACGATAACCCTGACGCGCTC
GAGGCCATGATGATGACGCTGCAGACACTTGGCCATACGGTGGTGACCGCCGCCGACGGCCCCAGCGCGCTGGCGCGCGC
CACCGATGCCCGGCCGGAGGTGGTGCTGCTGGACCTGGGCATGCCCGCCATGGACGGCTTCGAGACCGCGCGCCGCCTGC
GCGCGCTGCCCGAGATGCGCGGCGCCACGCTGGTGGCGCTGACCGGCTTCGGCCAGCCCGAGGACCGCCGCCGCGCGCTG
GAAGCCGGCTTCGACCAGCACCTGGTCAAGCCGGCCGACCTGGACGCGCTGACACGGCTGCTGGATGCACTCAGCGCGGA
CCATTCCTAG

Upstream 100 bases:

>100_bases
GCAGCGCGGCCGGCGCGGTTTTACACGGCGCCGCCGCGGACCATCCCGGGCCCTGAGCAAACCTCCGCGCGGGCGCGCAA
GCGCCTGTCAGCGTGATGCC

Downstream 100 bases:

>100_bases
CGCGATGCCGATGCCAGCCGCCGCTCCCATCCACCCTTGAACAAGGAAGCTCCGTGCATACCACGCCCGATCCCGACATC
CCGCCGCGCAAGCCTGAAAC

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MTPHAANPAPLILNVDDREGPRYVKSRILHRGEYSVIEAATGHSALSLVRQHAPVLVLLAARLPDISGLEVCRLLKADPQ
TAHTLVLLTSPGLAQSRQRVEALNCGADGYLVEPAEPEEVLSSIQALLRLRGAEDAYHRTSRALHEHEDMFRQVAESLAD
VVWILDPAEPRLLFASPSLATLCGHKPEQLTQEPRRCLERVAPADRARVEAAFASMLGDGRLDIEFRLARPDGELRDIRA
RAFPVRGAEGQPGDDRTPPLRIAGTCQDVTLQNRAGRALHDEERRKDQFLAMLAHELRNPLAPLRSAADLLQQLSPSRED
MFRARDIIGRQLHHLTRLVDELLDISRFNQGRITLREDLVELRTALNTAVEAVRPTMDACGHTLRLSLPEQPLPVRGDLV
RLAQIFSNLLQNAAAYTPAGGQIVVDASLEDGAANTAPDAASGARVTVRVRDNGAGLSEALQRQLFDPLAARDDGTQPEP
PRSAIQQDGPGIGLTLVQKLVRLHGGTIRADSPGPGQGSTFTVTLPVEPWQKWHPGSGRTAPHRGVPRRIMVVDDNPDAL
EAMMMTLQTLGHTVVTAADGPSALARATDARPEVVLLDLGMPAMDGFETARRLRALPEMRGATLVALTGFGQPEDRRRAL
EAGFDQHLVKPADLDALTRLLDALSADHS

Sequences:

>Translated_669_residues
MTPHAANPAPLILNVDDREGPRYVKSRILHRGEYSVIEAATGHSALSLVRQHAPVLVLLAARLPDISGLEVCRLLKADPQ
TAHTLVLLTSPGLAQSRQRVEALNCGADGYLVEPAEPEEVLSSIQALLRLRGAEDAYHRTSRALHEHEDMFRQVAESLAD
VVWILDPAEPRLLFASPSLATLCGHKPEQLTQEPRRCLERVAPADRARVEAAFASMLGDGRLDIEFRLARPDGELRDIRA
RAFPVRGAEGQPGDDRTPPLRIAGTCQDVTLQNRAGRALHDEERRKDQFLAMLAHELRNPLAPLRSAADLLQQLSPSRED
MFRARDIIGRQLHHLTRLVDELLDISRFNQGRITLREDLVELRTALNTAVEAVRPTMDACGHTLRLSLPEQPLPVRGDLV
RLAQIFSNLLQNAAAYTPAGGQIVVDASLEDGAANTAPDAASGARVTVRVRDNGAGLSEALQRQLFDPLAARDDGTQPEP
PRSAIQQDGPGIGLTLVQKLVRLHGGTIRADSPGPGQGSTFTVTLPVEPWQKWHPGSGRTAPHRGVPRRIMVVDDNPDAL
EAMMMTLQTLGHTVVTAADGPSALARATDARPEVVLLDLGMPAMDGFETARRLRALPEMRGATLVALTGFGQPEDRRRAL
EAGFDQHLVKPADLDALTRLLDALSADHS
>Mature_668_residues
TPHAANPAPLILNVDDREGPRYVKSRILHRGEYSVIEAATGHSALSLVRQHAPVLVLLAARLPDISGLEVCRLLKADPQT
AHTLVLLTSPGLAQSRQRVEALNCGADGYLVEPAEPEEVLSSIQALLRLRGAEDAYHRTSRALHEHEDMFRQVAESLADV
VWILDPAEPRLLFASPSLATLCGHKPEQLTQEPRRCLERVAPADRARVEAAFASMLGDGRLDIEFRLARPDGELRDIRAR
AFPVRGAEGQPGDDRTPPLRIAGTCQDVTLQNRAGRALHDEERRKDQFLAMLAHELRNPLAPLRSAADLLQQLSPSREDM
FRARDIIGRQLHHLTRLVDELLDISRFNQGRITLREDLVELRTALNTAVEAVRPTMDACGHTLRLSLPEQPLPVRGDLVR
LAQIFSNLLQNAAAYTPAGGQIVVDASLEDGAANTAPDAASGARVTVRVRDNGAGLSEALQRQLFDPLAARDDGTQPEPP
RSAIQQDGPGIGLTLVQKLVRLHGGTIRADSPGPGQGSTFTVTLPVEPWQKWHPGSGRTAPHRGVPRRIMVVDDNPDALE
AMMMTLQTLGHTVVTAADGPSALARATDARPEVVLLDLGMPAMDGFETARRLRALPEMRGATLVALTGFGQPEDRRRALE
AGFDQHLVKPADLDALTRLLDALSADHS

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=420, Percent_Identity=29.5238095238095, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI48994928, Length=497, Percent_Identity=26.7605633802817, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786912, Length=273, Percent_Identity=29.6703296703297, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=28.3524904214559, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=258, Percent_Identity=30.6201550387597, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=313, Percent_Identity=28.7539936102236, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=260, Percent_Identity=29.2307692307692, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=301, Percent_Identity=25.9136212624585, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=357, Percent_Identity=26.6106442577031, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786783, Length=293, Percent_Identity=24.9146757679181, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=252, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=23.9669421487603, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=25.6, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72842; Mature: 72711

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHAANPAPLILNVDDREGPRYVKSRILHRGEYSVIEAATGHSALSLVRQHAPVLVLLA
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEHH
ARLPDISGLEVCRLLKADPQTAHTLVLLTSPGLAQSRQRVEALNCGADGYLVEPAEPEEV
HHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCHHHH
LSSIQALLRLRGAEDAYHRTSRALHEHEDMFRQVAESLADVVWILDPAEPRLLFASPSLA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCCHH
TLCGHKPEQLTQEPRRCLERVAPADRARVEAAFASMLGDGRLDIEFRLARPDGELRDIRA
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHH
RAFPVRGAEGQPGDDRTPPLRIAGTCQDVTLQNRAGRALHDEERRKDQFLAMLAHELRNP
HHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCH
LAPLRSAADLLQQLSPSREDMFRARDIIGRQLHHLTRLVDELLDISRFNQGRITLREDLV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ELRTALNTAVEAVRPTMDACGHTLRLSLPEQPLPVRGDLVRLAQIFSNLLQNAAAYTPAG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GQIVVDASLEDGAANTAPDAASGARVTVRVRDNGAGLSEALQRQLFDPLAARDDGTQPEP
CEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PRSAIQQDGPGIGLTLVQKLVRLHGGTIRADSPGPGQGSTFTVTLPVEPWQKWHPGSGRT
CHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCHHHCCCCCCCC
APHRGVPRRIMVVDDNPDALEAMMMTLQTLGHTVVTAADGPSALARATDARPEVVLLDLG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCEEEEECC
MPAMDGFETARRLRALPEMRGATLVALTGFGQPEDRRRALEAGFDQHLVKPADLDALTRL
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHH
LDALSADHS
HHHHHCCCC
>Mature Secondary Structure 
TPHAANPAPLILNVDDREGPRYVKSRILHRGEYSVIEAATGHSALSLVRQHAPVLVLLA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCEEEEHH
ARLPDISGLEVCRLLKADPQTAHTLVLLTSPGLAQSRQRVEALNCGADGYLVEPAEPEEV
HHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEECCCCHHHH
LSSIQALLRLRGAEDAYHRTSRALHEHEDMFRQVAESLADVVWILDPAEPRLLFASPSLA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEECCCHH
TLCGHKPEQLTQEPRRCLERVAPADRARVEAAFASMLGDGRLDIEFRLARPDGELRDIRA
HHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHH
RAFPVRGAEGQPGDDRTPPLRIAGTCQDVTLQNRAGRALHDEERRKDQFLAMLAHELRNP
HHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCH
LAPLRSAADLLQQLSPSREDMFRARDIIGRQLHHLTRLVDELLDISRFNQGRITLREDLV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ELRTALNTAVEAVRPTMDACGHTLRLSLPEQPLPVRGDLVRLAQIFSNLLQNAAAYTPAG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
GQIVVDASLEDGAANTAPDAASGARVTVRVRDNGAGLSEALQRQLFDPLAARDDGTQPEP
CEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCC
PRSAIQQDGPGIGLTLVQKLVRLHGGTIRADSPGPGQGSTFTVTLPVEPWQKWHPGSGRT
CHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCHHHCCCCCCCC
APHRGVPRRIMVVDDNPDALEAMMMTLQTLGHTVVTAADGPSALARATDARPEVVLLDLG
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCCEEEEECC
MPAMDGFETARRLRALPEMRGATLVALTGFGQPEDRRRALEAGFDQHLVKPADLDALTRL
CCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCHHHHCCCCCCHHHHHHH
LDALSADHS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]