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The map label for this gene is nahR [H]

Identifier: 116696252

GI number: 116696252

Start: 2626417

End: 2627310

Strand: Direct

Name: nahR [H]

Synonym: H16_B2316

Alternate gene names: 116696252

Gene position: 2626417-2627310 (Clockwise)

Preceding gene: 116696244

Following gene: 116696253

Centisome position: 90.18

GC content: 68.68

Gene sequence:

>894_bases
ATGAATAATCTCAGACGGCTGGACCTGAACCTGCTGGTGACGCTGGATGTGCTGCTGTCCGAGCACAACGTGACCCGCGC
GGCGCAGCGGCTGCACCTGTCGCAGCCTTCGGTCAGCGTCCACTTGTCGAGGCTGCGCGATTACTTCGGTGACCCGCTGC
TGTTGCCGGGCCCGCGCGGCATGCGTCCCACCGCCAAGGCGGAATCGCTGCGCGAACCGTTGCGCGAAGCGCTGGCCGCG
CTGGAGCATGCGGTCTCGTCCGATACGCCGTTCGATCCCGCCGCCTCGACCCACACCTGGCGCGTGGCTGCGACCGACTA
CGGCGAATCGACCATCGTGCTGCCGGCGCTGCAGGCGCTGCGCATGGCGGCGCCCGGCGCGCGCCTGGCCGTGGTCGAGA
TGGTGCCGCCGCGCATCGCCCGGCAGGCCGAGCGTGCCGAACTGGACCTGGCCTTCCATACCACCGATGGCTCGCCGCCG
GGCCTGCACCGGCGTGCGCTGTTTACCGAGCGCTATGTGCTGGTGGGCCGCGCCGGCCATCCGCGGCTGAAGCGGCGGCC
CACGCTGGCGCAGTTCTGCGCGCTCGACCATGTGATTGTGTCGCCGGACGGTGGCGGCTTCTACGGCGTCACCGACGAGG
CGCTGGTACTGGCCGGCATGCAGCGGCGTGTGGTGCTGTCAGTGCCCCACTTCCTGTTTGTCACGTCGGCCGTTGCCAGC
ACCGATCTGGTGGCGATGCTGCCCGAGCGGCTGGTGCGCGGCGTGCCGGGACTGAAGGTGGTGGAACCACCAGTCGAAGT
GCCGGGCTATGAGATGTCGATGTTGTGGCCAGAGCGCGTGCATCGCGATCCGGCGCATAGTTGGCTGCGTGAACTCATCG
TCACATCGGTCTGA

Upstream 100 bases:

>100_bases
GCAATACGTTCATGACAGCGGCTTCCAATGATTGAGTGAACCCAGCATAGGCCGTCGTCAGCTATATTAGAAATGAATAT
CCAATATCCCAGGTATTGTC

Downstream 100 bases:

>100_bases
GCGGCGCTGCCTCGCACGTTTGCATACAAAACTGGAATACAATCAGCTCTTTCAACGCTGCGGCATGGGGTGGTACCCGG
TGCCGCCCCAGTTTTGGAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNNLRRLDLNLLVTLDVLLSEHNVTRAAQRLHLSQPSVSVHLSRLRDYFGDPLLLPGPRGMRPTAKAESLREPLREALAA
LEHAVSSDTPFDPAASTHTWRVAATDYGESTIVLPALQALRMAAPGARLAVVEMVPPRIARQAERAELDLAFHTTDGSPP
GLHRRALFTERYVLVGRAGHPRLKRRPTLAQFCALDHVIVSPDGGGFYGVTDEALVLAGMQRRVVLSVPHFLFVTSAVAS
TDLVAMLPERLVRGVPGLKVVEPPVEVPGYEMSMLWPERVHRDPAHSWLRELIVTSV

Sequences:

>Translated_297_residues
MNNLRRLDLNLLVTLDVLLSEHNVTRAAQRLHLSQPSVSVHLSRLRDYFGDPLLLPGPRGMRPTAKAESLREPLREALAA
LEHAVSSDTPFDPAASTHTWRVAATDYGESTIVLPALQALRMAAPGARLAVVEMVPPRIARQAERAELDLAFHTTDGSPP
GLHRRALFTERYVLVGRAGHPRLKRRPTLAQFCALDHVIVSPDGGGFYGVTDEALVLAGMQRRVVLSVPHFLFVTSAVAS
TDLVAMLPERLVRGVPGLKVVEPPVEVPGYEMSMLWPERVHRDPAHSWLRELIVTSV
>Mature_297_residues
MNNLRRLDLNLLVTLDVLLSEHNVTRAAQRLHLSQPSVSVHLSRLRDYFGDPLLLPGPRGMRPTAKAESLREPLREALAA
LEHAVSSDTPFDPAASTHTWRVAATDYGESTIVLPALQALRMAAPGARLAVVEMVPPRIARQAERAELDLAFHTTDGSPP
GLHRRALFTERYVLVGRAGHPRLKRRPTLAQFCALDHVIVSPDGGGFYGVTDEALVLAGMQRRVVLSVPHFLFVTSAVAS
TDLVAMLPERLVRGVPGLKVVEPPVEVPGYEMSMLWPERVHRDPAHSWLRELIVTSV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=303, Percent_Identity=28.0528052805281, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87081766, Length=288, Percent_Identity=24.6527777777778, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790147, Length=304, Percent_Identity=24.6710526315789, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32705; Mature: 32705

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLRRLDLNLLVTLDVLLSEHNVTRAAQRLHLSQPSVSVHLSRLRDYFGDPLLLPGPRG
CCCCCEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCC
MRPTAKAESLREPLREALAALEHAVSSDTPFDPAASTHTWRVAATDYGESTIVLPALQAL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHH
RMAAPGARLAVVEMVPPRIARQAERAELDLAFHTTDGSPPGLHRRALFTERYVLVGRAGH
HHCCCCCEEEEEECCCHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHCEEEEECCCC
PRLKRRPTLAQFCALDHVIVSPDGGGFYGVTDEALVLAGMQRRVVLSVPHFLFVTSAVAS
CCCCCCCCHHHHHHHCCEEECCCCCCEECCCHHHHHHHCCCCEEEEECHHHHHHHHHHHH
TDLVAMLPERLVRGVPGLKVVEPPVEVPGYEMSMLWPERVHRDPAHSWLRELIVTSV
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNLRRLDLNLLVTLDVLLSEHNVTRAAQRLHLSQPSVSVHLSRLRDYFGDPLLLPGPRG
CCCCCEECHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEECCCCCC
MRPTAKAESLREPLREALAALEHAVSSDTPFDPAASTHTWRVAATDYGESTIVLPALQAL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHH
RMAAPGARLAVVEMVPPRIARQAERAELDLAFHTTDGSPPGLHRRALFTERYVLVGRAGH
HHCCCCCEEEEEECCCHHHHHHHHHCEEEEEEEECCCCCCCCHHHHHHHHCEEEEECCCC
PRLKRRPTLAQFCALDHVIVSPDGGGFYGVTDEALVLAGMQRRVVLSVPHFLFVTSAVAS
CCCCCCCCHHHHHHHCCEEECCCCCCEECCCHHHHHHHCCCCEEEEECHHHHHHHHHHHH
TDLVAMLPERLVRGVPGLKVVEPPVEVPGYEMSMLWPERVHRDPAHSWLRELIVTSV
HHHHHHHHHHHHCCCCCCEEECCCCCCCCCEEEEECHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]