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The map label for this gene is 116696243

Identifier: 116696243

GI number: 116696243

Start: 2608866

End: 2610320

Strand: Direct

Name: 116696243

Synonym: H16_B2307

Alternate gene names: NA

Gene position: 2608866-2610320 (Clockwise)

Preceding gene: 116696241

Following gene: 116696244

Centisome position: 89.58

GC content: 72.65

Gene sequence:

>1455_bases
ATGGCGCCCACCCGGACCCCCGATCCCATCACCGAACTCGATGCCGTCGCCCTGTCGCGCGCCATCCATGCGCGCGAGGT
CTCGTGCGTGGAAGTGCTCGATGCCTTCCTTGGCCAGATCGACCGCCACAACCCGCGCGTCAATGCCATCGTGGCTCCGG
TGGAGCGCGACACCCTGCGCGCGCAGGCCGCCGGGCTCGACGCCGAACTGGCACGCGGCGCCAGCCGCGGCCCGCTGCAC
GGCTTCCCGCAGGCGCCCAAGGACATCAGCCCGGCCGCGGGCATGGTCACCACCAAGGGCTCGCCGATCTTCGCCGGGCA
GGTCAGCGAGTACGACGCCGTGATCTTCGAGCGCATGCGCGCCGGCGGCGCGGTCTTCGTCGGGCGCACCAACTCGCCGG
AGTTCGGCCTGGGCGGCCATACCTACAACCCGGTCTACGGCACCACCCGCAACGCCTTCGACCCGGCGCGTTCCGCCGGC
GGCAGCAGCGGCGGCGCCGCGGTGGCCGTGGCGCTGCACATGCTGCCGGTGGCGGATGGCTCTGACATGATGGGGTCGCT
GCGCACGCCCGCGGCGTTCAACCACGTGTATGGCCTGCGCACCTCGGTCGGCTGCGTGCCGCACGGCCCGGGCGATGAGG
TCTTCTTCCAGCAGTTCAGCGTGGCCGGCCCGATGGCGCGCAACGTGCCGGACCTGGCCCTGCTGCTGTCGGTGCAGGCC
GGCTTCGACGCGCGTCTGCCGCTGACGCACCGCGCCGAAGCGCCCGGCACCTTCACGCTGCCGCCCGAACGCGACTGGGC
CGGCGTGCGCATCGGCTGGCTGGGCAACCTGGGCGGCCACCTGCCGACCGAAGCCGGCGTGCTAGATACTTGCGAGCAGG
CACTCACGCACCTGCGCACGCTCGGCTGCACCGTGGACACCGCGCTGCCCGAGTTCGACCTGGAGCGACTGTGGCACGCG
TGGATCGACCTGCGCAGCTTCTCGGTGGCTGGCGCCAACGCGGCGCTGTACCACGACCCGGCCAGGCGCGCGCTGCTCAA
GCCCGAGGCCGCATGGGAGATCGAGCGCGGCCTGGCCCTGCCGGGCACGCGCGTGTACGAAGCCCTGTGCGAGCGCAGCG
CCTGGTACCAGGCACTGCGCTCGCTGTTCGAGCGCTTCGACTACCTGGTGCTGCCGGCCGCGCAGGTGTTTCCGTTCGAT
GCCGACTGGGACTGGCCGCACACCATCGACGGCCGCGACATGGACACCTACCACCGCTGGATGCAGGTCGTGGTGCCGGC
CACCATGGCCGGGCTGCCCGCCCTGGCCGCACCCGCCGGCTTCGGCCCCCAGGGCCTGCCGGCCGGCATCCAGATCATCG
GCCCCGCGCAGGCCGACGCCGCCGTGCTGCAGCTCGGCCATGCCTATGACCAGGCCGGCGGCTTCTCGCGCGTGCGCAGC
CCCTGGCTCGATTGA

Upstream 100 bases:

>100_bases
GTTTGCGTTTTACGCAAGGATATTTGAAAAAATCATCGATTGCGGGAAACCGTGCGCCGCCCGTATGCTTTTTCCCGACA
CCACAGGAGACCCCCGAGCC

Downstream 100 bases:

>100_bases
GCCTTCGGCTGGTCCCGGCCCCGCTTCATATTGCTTCCGATTGCCTTCTATTCCTACAACTGCCGGCAGGAGTGCCAACG
ATGACCGCAATGCCCCCGAA

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAPTRTPDPITELDAVALSRAIHAREVSCVEVLDAFLGQIDRHNPRVNAIVAPVERDTLRAQAAGLDAELARGASRGPLH
GFPQAPKDISPAAGMVTTKGSPIFAGQVSEYDAVIFERMRAGGAVFVGRTNSPEFGLGGHTYNPVYGTTRNAFDPARSAG
GSSGGAAVAVALHMLPVADGSDMMGSLRTPAAFNHVYGLRTSVGCVPHGPGDEVFFQQFSVAGPMARNVPDLALLLSVQA
GFDARLPLTHRAEAPGTFTLPPERDWAGVRIGWLGNLGGHLPTEAGVLDTCEQALTHLRTLGCTVDTALPEFDLERLWHA
WIDLRSFSVAGANAALYHDPARRALLKPEAAWEIERGLALPGTRVYEALCERSAWYQALRSLFERFDYLVLPAAQVFPFD
ADWDWPHTIDGRDMDTYHRWMQVVVPATMAGLPALAAPAGFGPQGLPAGIQIIGPAQADAAVLQLGHAYDQAGGFSRVRS
PWLD

Sequences:

>Translated_484_residues
MAPTRTPDPITELDAVALSRAIHAREVSCVEVLDAFLGQIDRHNPRVNAIVAPVERDTLRAQAAGLDAELARGASRGPLH
GFPQAPKDISPAAGMVTTKGSPIFAGQVSEYDAVIFERMRAGGAVFVGRTNSPEFGLGGHTYNPVYGTTRNAFDPARSAG
GSSGGAAVAVALHMLPVADGSDMMGSLRTPAAFNHVYGLRTSVGCVPHGPGDEVFFQQFSVAGPMARNVPDLALLLSVQA
GFDARLPLTHRAEAPGTFTLPPERDWAGVRIGWLGNLGGHLPTEAGVLDTCEQALTHLRTLGCTVDTALPEFDLERLWHA
WIDLRSFSVAGANAALYHDPARRALLKPEAAWEIERGLALPGTRVYEALCERSAWYQALRSLFERFDYLVLPAAQVFPFD
ADWDWPHTIDGRDMDTYHRWMQVVVPATMAGLPALAAPAGFGPQGLPAGIQIIGPAQADAAVLQLGHAYDQAGGFSRVRS
PWLD
>Mature_483_residues
APTRTPDPITELDAVALSRAIHAREVSCVEVLDAFLGQIDRHNPRVNAIVAPVERDTLRAQAAGLDAELARGASRGPLHG
FPQAPKDISPAAGMVTTKGSPIFAGQVSEYDAVIFERMRAGGAVFVGRTNSPEFGLGGHTYNPVYGTTRNAFDPARSAGG
SSGGAAVAVALHMLPVADGSDMMGSLRTPAAFNHVYGLRTSVGCVPHGPGDEVFFQQFSVAGPMARNVPDLALLLSVQAG
FDARLPLTHRAEAPGTFTLPPERDWAGVRIGWLGNLGGHLPTEAGVLDTCEQALTHLRTLGCTVDTALPEFDLERLWHAW
IDLRSFSVAGANAALYHDPARRALLKPEAAWEIERGLALPGTRVYEALCERSAWYQALRSLFERFDYLVLPAAQVFPFDA
DWDWPHTIDGRDMDTYHRWMQVVVPATMAGLPALAAPAGFGPQGLPAGIQIIGPAQADAAVLQLGHAYDQAGGFSRVRSP
WLD

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=510, Percent_Identity=24.9019607843137, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI222831590, Length=281, Percent_Identity=27.4021352313167, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537465, Length=251, Percent_Identity=28.6852589641434, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17543272, Length=440, Percent_Identity=26.8181818181818, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17556264, Length=196, Percent_Identity=31.1224489795918, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538252, Length=312, Percent_Identity=27.2435897435897, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17556276, Length=277, Percent_Identity=30.3249097472924, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556278, Length=277, Percent_Identity=30.3249097472924, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71990152, Length=223, Percent_Identity=29.1479820627803, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538254, Length=196, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319685, Length=443, Percent_Identity=28.6681715575621, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320448, Length=239, Percent_Identity=29.2887029288703, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550774, Length=242, Percent_Identity=30.9917355371901, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24648435, Length=242, Percent_Identity=30.9917355371901, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24648437, Length=242, Percent_Identity=30.9917355371901, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24652985, Length=252, Percent_Identity=32.9365079365079, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19922090, Length=252, Percent_Identity=32.9365079365079, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652981, Length=252, Percent_Identity=32.9365079365079, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24652983, Length=252, Percent_Identity=32.9365079365079, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644968, Length=500, Percent_Identity=24.8, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356731, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI161078093, Length=503, Percent_Identity=22.6640159045726, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24648113, Length=450, Percent_Identity=28.6666666666667, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24648441, Length=167, Percent_Identity=32.9341317365269, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648439, Length=167, Percent_Identity=32.9341317365269, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 51784; Mature: 51653

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTRTPDPITELDAVALSRAIHAREVSCVEVLDAFLGQIDRHNPRVNAIVAPVERDTLR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
AQAAGLDAELARGASRGPLHGFPQAPKDISPAAGMVTTKGSPIFAGQVSEYDAVIFERMR
HHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHHH
AGGAVFVGRTNSPEFGLGGHTYNPVYGTTRNAFDPARSAGGSSGGAAVAVALHMLPVADG
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
SDMMGSLRTPAAFNHVYGLRTSVGCVPHGPGDEVFFQQFSVAGPMARNVPDLALLLSVQA
CHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCEEEEEEHHC
GFDARLPLTHRAEAPGTFTLPPERDWAGVRIGWLGNLGGHLPTEAGVLDTCEQALTHLRT
CCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
LGCTVDTALPEFDLERLWHAWIDLRSFSVAGANAALYHDPARRALLKPEAAWEIERGLAL
HCCHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECHHHHHHCCCHHHHHHHCCCCC
PGTRVYEALCERSAWYQALRSLFERFDYLVLPAAQVFPFDADWDWPHTIDGRDMDTYHRW
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHHH
MQVVVPATMAGLPALAAPAGFGPQGLPAGIQIIGPAQADAAVLQLGHAYDQAGGFSRVRS
HHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHCC
PWLD
CCCC
>Mature Secondary Structure 
APTRTPDPITELDAVALSRAIHAREVSCVEVLDAFLGQIDRHNPRVNAIVAPVERDTLR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHH
AQAAGLDAELARGASRGPLHGFPQAPKDISPAAGMVTTKGSPIFAGQVSEYDAVIFERMR
HHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHHH
AGGAVFVGRTNSPEFGLGGHTYNPVYGTTRNAFDPARSAGGSSGGAAVAVALHMLPVADG
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCC
SDMMGSLRTPAAFNHVYGLRTSVGCVPHGPGDEVFFQQFSVAGPMARNVPDLALLLSVQA
CHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCEEEEEEHHC
GFDARLPLTHRAEAPGTFTLPPERDWAGVRIGWLGNLGGHLPTEAGVLDTCEQALTHLRT
CCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
LGCTVDTALPEFDLERLWHAWIDLRSFSVAGANAALYHDPARRALLKPEAAWEIERGLAL
HCCHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCEEEECHHHHHHCCCHHHHHHHCCCCC
PGTRVYEALCERSAWYQALRSLFERFDYLVLPAAQVFPFDADWDWPHTIDGRDMDTYHRW
CCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCCCCCCCCCCCCCCHHHHHHH
MQVVVPATMAGLPALAAPAGFGPQGLPAGIQIIGPAQADAAVLQLGHAYDQAGGFSRVRS
HHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHCC
PWLD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]