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The map label for this gene is can2 [H]

Identifier: 116696206

GI number: 116696206

Start: 2570570

End: 2571277

Strand: Direct

Name: can2 [H]

Synonym: H16_B2270

Alternate gene names: 116696206

Gene position: 2570570-2571277 (Clockwise)

Preceding gene: 116696205

Following gene: 116696207

Centisome position: 88.26

GC content: 69.07

Gene sequence:

>708_bases
ATGCATCACATCGAACAACTGCTCAAAGGTTTCGAACGCTTCCAGCAACGCTATTTCGACGACGAGCCCGGGCTGTTCGA
CACGCTGCGCACCGGCCAGCGCCCGCCCACGCTGCTGATCGGCTGCAGCGATTCACGCGTCGATCCTGGCCTGCTGCTGG
GCTGCGATCCGGGCGAGCTCTTTACCGTGCGCAATATCGGCAACCTGGTGCCACCGTGCACCGGCCGCCATGAAGGCAGC
CTGCACGGCGTATGCGCGGCGATCCAGTTTGCCGTGCAGCAGCTGCGCGTGGCCCGCATCATCGTGATGGGCCACGGCGG
CTGCGGCGGCATCCGCGCCTTGCTGGCGCAGCCGGCCGACGCCGGCGACCATGCGCCCGACGAAAGCGAAGACCCCGACT
ACATCGGCGCCTGGGTGCGCATCGCGGCACCGGCGCGCAGACAGGTGGAGGAAGCCCTGGCCGCGGCCAGCGCCGCCGAG
CGCCAGCGCGCCTGCGAACAGGCGGCGATCCTGGTGTCGCTGCGCAACCTGCAGACTTTCCCGTTCGTGCGGCGCGCACT
GGAGGCCGGCACGCTGACGCTGCACGGCTGGTATTTCGACCTGCAGGCCGGCGCGCTGCTGGCCTATTCGCAGCGTGCCG
ACAGCTTCCTGCCGCTGGTGTGCCCGCTGCCCGCCCAAACTGAACTCCGCGAACCCTGCGAACCCTGA

Upstream 100 bases:

>100_bases
GAAGCAGTACGCCAGCCTGCTGATCGGGCGCGCGCGCATCGAAGGCATCGAGCTGGAGGGCGCCGACAGCCCGCTGGTGC
AGTAGCGCCTGGATGCCGCC

Downstream 100 bases:

>100_bases
CCCCATGCATCCCTTCATCCTTGGCATTACCGGCACCTCCGGCAGCGGCAAGACCACGCTGATCACGGCACTGCTGCCGT
GGTTCCGCGCACAGGGCCTG

Product: Beta-carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MHHIEQLLKGFERFQQRYFDDEPGLFDTLRTGQRPPTLLIGCSDSRVDPGLLLGCDPGELFTVRNIGNLVPPCTGRHEGS
LHGVCAAIQFAVQQLRVARIIVMGHGGCGGIRALLAQPADAGDHAPDESEDPDYIGAWVRIAAPARRQVEEALAAASAAE
RQRACEQAAILVSLRNLQTFPFVRRALEAGTLTLHGWYFDLQAGALLAYSQRADSFLPLVCPLPAQTELREPCEP

Sequences:

>Translated_235_residues
MHHIEQLLKGFERFQQRYFDDEPGLFDTLRTGQRPPTLLIGCSDSRVDPGLLLGCDPGELFTVRNIGNLVPPCTGRHEGS
LHGVCAAIQFAVQQLRVARIIVMGHGGCGGIRALLAQPADAGDHAPDESEDPDYIGAWVRIAAPARRQVEEALAAASAAE
RQRACEQAAILVSLRNLQTFPFVRRALEAGTLTLHGWYFDLQAGALLAYSQRADSFLPLVCPLPAQTELREPCEP
>Mature_235_residues
MHHIEQLLKGFERFQQRYFDDEPGLFDTLRTGQRPPTLLIGCSDSRVDPGLLLGCDPGELFTVRNIGNLVPPCTGRHEGS
LHGVCAAIQFAVQQLRVARIIVMGHGGCGGIRALLAQPADAGDHAPDESEDPDYIGAWVRIAAPARRQVEEALAAASAAE
RQRACEQAAILVSLRNLQTFPFVRRALEAGTLTLHGWYFDLQAGALLAYSQRADSFLPLVCPLPAQTELREPCEP

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=234, Percent_Identity=37.6068376068376, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786318, Length=207, Percent_Identity=28.5024154589372, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=243, Percent_Identity=25.1028806584362, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=214, Percent_Identity=26.1682242990654, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25632; Mature: 25632

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHIEQLLKGFERFQQRYFDDEPGLFDTLRTGQRPPTLLIGCSDSRVDPGLLLGCDPGEL
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCE
FTVRNIGNLVPPCTGRHEGSLHGVCAAIQFAVQQLRVARIIVMGHGGCGGIRALLAQPAD
EEECHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCC
AGDHAPDESEDPDYIGAWVRIAAPARRQVEEALAAASAAERQRACEQAAILVSLRNLQTF
CCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
PFVRRALEAGTLTLHGWYFDLQAGALLAYSQRADSFLPLVCPLPAQTELREPCEP
HHHHHHHHCCCEEEEEEEEEECCCCCEEEHHCCCCCCCEEECCCCCHHCCCCCCC
>Mature Secondary Structure
MHHIEQLLKGFERFQQRYFDDEPGLFDTLRTGQRPPTLLIGCSDSRVDPGLLLGCDPGEL
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEECCCCCCCCCEEEECCCCCE
FTVRNIGNLVPPCTGRHEGSLHGVCAAIQFAVQQLRVARIIVMGHGGCGGIRALLAQPAD
EEECHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCC
AGDHAPDESEDPDYIGAWVRIAAPARRQVEEALAAASAAERQRACEQAAILVSLRNLQTF
CCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
PFVRRALEAGTLTLHGWYFDLQAGALLAYSQRADSFLPLVCPLPAQTELREPCEP
HHHHHHHHCCCEEEEEEEEEECCCCCEEEHHCCCCCCCEEECCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]