Click here to switch to the map view.

The map label for this gene is tauD2 [C]

Identifier: 116696163

GI number: 116696163

Start: 2525280

End: 2526242

Strand: Direct

Name: tauD2 [C]

Synonym: H16_B2227

Alternate gene names: 116696163

Gene position: 2525280-2526242 (Clockwise)

Preceding gene: 116696162

Following gene: 116696164

Centisome position: 86.71

GC content: 70.09

Gene sequence:

>963_bases
ATGACCCAAGCCAACGCCACGCAAGACCAGACCGTCCAGCTCGACATCCACCCGGTTGCCGGCCGCATCGGCGCCGAGAT
CCGCGGCGTCGCGCTGCACGGCGACCTGCCGCCCGCCACCTTCGCCGCCATCCGCGCAGCCTTGCTCAGGCACAAGGTGC
TGTTCTTCCGCGACCAGGTCCATCTGGACGATGCCGCGCAGCAGGGCTTTGCGCGCCTGTTCGGCGACACCGTGCCGCAC
CCGACCGTGCCCTCGCGCGACGGCACGCAACTGCTTGAGCTCGACTCGCAGCACGGCGGCCGCGCCAATTCCTGGCATAC
CGACGTGACCTTCGACCTGGCCTACCCCGCGGTCTCGGTGCTGCGCGCCGTGACCGTTCCCGCCGCCGGCGGCGACACGG
TGTGGGCCAACACCGCTGCCGCGTACCAGGACCTGCCCGAGCCGCTGCGCGAACTGGCCGACAAGCTGTGGGCACTGCAC
ACCAACGACTACGACTACGCGGCCACGCGCGTCAATCCGAGCGACGAAGGGTTGAAGCGCTACCGCGAGCTATTTACCTC
GGCGCTCTACGAGACCGAGCACCCGGTGGTGCGCGTGCATCCGGAAACCGGTGAACGCACGCTGGTGCTGGGCCACTTCG
TCAAGAAGCTGCTGGACTACTCGTCGGCCGATTCGGCGCACCTGATTGCCGTGCTGCAGGGCCATGTGCACCGGCTGGAG
AACACCGTGCGCTGGCGCTGGCGCGCGGGCGACGTCGCCATCTGGGACAACCGCGCCACCCAGCACTACGCCATCAACGA
CTATGGCGACGCGCACCGCGTGGTACGCCGGGCCACCGTGGCCGGCGACATCCCGGTCGGCGTGGATGGCCGCCGCAGCA
AGGCGGTGAAGGCGGGCGTGCGCAACGAAGGCGCGGCGCCGGCCAACCAGTCCGCCGGTGCCGCGCAACGGCAAGCGGCC
TGA

Upstream 100 bases:

>100_bases
GCCGTGCTGCGCGAATTCGCCGGGCCGGAGCCTGTCGTGCAGCGGACCCCCGAACCTGAACTCGCCTGACCCAACCCTCT
TACATCCCCGGAGCTTCGCG

Downstream 100 bases:

>100_bases
TTTGGCCAGTTGCTTCCGGGGAGCACGATCCATGTCACAGCAAAAGCCGGCGCGCCAGCTGCATCTGGGCGCCTTTCTCC
AGGCCACCGGGCACCATGTC

Product: taurine catabolism dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTQANATQDQTVQLDIHPVAGRIGAEIRGVALHGDLPPATFAAIRAALLRHKVLFFRDQVHLDDAAQQGFARLFGDTVPH
PTVPSRDGTQLLELDSQHGGRANSWHTDVTFDLAYPAVSVLRAVTVPAAGGDTVWANTAAAYQDLPEPLRELADKLWALH
TNDYDYAATRVNPSDEGLKRYRELFTSALYETEHPVVRVHPETGERTLVLGHFVKKLLDYSSADSAHLIAVLQGHVHRLE
NTVRWRWRAGDVAIWDNRATQHYAINDYGDAHRVVRRATVAGDIPVGVDGRRSKAVKAGVRNEGAAPANQSAGAAQRQAA

Sequences:

>Translated_320_residues
MTQANATQDQTVQLDIHPVAGRIGAEIRGVALHGDLPPATFAAIRAALLRHKVLFFRDQVHLDDAAQQGFARLFGDTVPH
PTVPSRDGTQLLELDSQHGGRANSWHTDVTFDLAYPAVSVLRAVTVPAAGGDTVWANTAAAYQDLPEPLRELADKLWALH
TNDYDYAATRVNPSDEGLKRYRELFTSALYETEHPVVRVHPETGERTLVLGHFVKKLLDYSSADSAHLIAVLQGHVHRLE
NTVRWRWRAGDVAIWDNRATQHYAINDYGDAHRVVRRATVAGDIPVGVDGRRSKAVKAGVRNEGAAPANQSAGAAQRQAA
>Mature_319_residues
TQANATQDQTVQLDIHPVAGRIGAEIRGVALHGDLPPATFAAIRAALLRHKVLFFRDQVHLDDAAQQGFARLFGDTVPHP
TVPSRDGTQLLELDSQHGGRANSWHTDVTFDLAYPAVSVLRAVTVPAAGGDTVWANTAAAYQDLPEPLRELADKLWALHT
NDYDYAATRVNPSDEGLKRYRELFTSALYETEHPVVRVHPETGERTLVLGHFVKKLLDYSSADSAHLIAVLQGHVHRLEN
TVRWRWRAGDVAIWDNRATQHYAINDYGDAHRVVRRATVAGDIPVGVDGRRSKAVKAGVRNEGAAPANQSAGAAQRQAA

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=278, Percent_Identity=37.410071942446, Blast_Score=180, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322971, Length=293, Percent_Identity=27.9863481228669, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 35020; Mature: 34889

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQANATQDQTVQLDIHPVAGRIGAEIRGVALHGDLPPATFAAIRAALLRHKVLFFRDQV
CCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
HLDDAAQQGFARLFGDTVPHPTVPSRDGTQLLELDSQHGGRANSWHTDVTFDLAYPAVSV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHH
LRAVTVPAAGGDTVWANTAAAYQDLPEPLRELADKLWALHTNDYDYAATRVNPSDEGLKR
HHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCHHHHHH
YRELFTSALYETEHPVVRVHPETGERTLVLGHFVKKLLDYSSADSAHLIAVLQGHVHRLE
HHHHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NTVRWRWRAGDVAIWDNRATQHYAINDYGDAHRVVRRATVAGDIPVGVDGRRSKAVKAGV
HHHEEEEECCCEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
RNEGAAPANQSAGAAQRQAA
CCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TQANATQDQTVQLDIHPVAGRIGAEIRGVALHGDLPPATFAAIRAALLRHKVLFFRDQV
CCCCCCCCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
HLDDAAQQGFARLFGDTVPHPTVPSRDGTQLLELDSQHGGRANSWHTDVTFDLAYPAVSV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEHHHHHHHH
LRAVTVPAAGGDTVWANTAAAYQDLPEPLRELADKLWALHTNDYDYAATRVNPSDEGLKR
HHHHHCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEECCCCHHHHHH
YRELFTSALYETEHPVVRVHPETGERTLVLGHFVKKLLDYSSADSAHLIAVLQGHVHRLE
HHHHHHHHHHCCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NTVRWRWRAGDVAIWDNRATQHYAINDYGDAHRVVRRATVAGDIPVGVDGRRSKAVKAGV
HHHEEEEECCCEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
RNEGAAPANQSAGAAQRQAA
CCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]