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The map label for this gene is yafC [H]

Identifier: 116695836

GI number: 116695836

Start: 2147705

End: 2148709

Strand: Direct

Name: yafC [H]

Synonym: H16_B1900

Alternate gene names: 116695836

Gene position: 2147705-2148709 (Clockwise)

Preceding gene: 116695835

Following gene: 116695837

Centisome position: 73.74

GC content: 69.15

Gene sequence:

>1005_bases
GTGGCGGCCCACGCCCGCCGGTTGTCCCCAAATCGGCACTATGATGGCGGCATTCTCCACCATCCGTTGCCAGTCATGGA
CAAGGCCCGTGTCCTCACCCTCTTCCTCGGCGTGGTACGCGCCGGCAGCTTCCACCGCGCCGCGGTGGAAGCTGGCGTCA
CCCCGCAGGCCGCCAGCAAGGCCGTGCGCACGCTGGAGGATCATCTCGGCGTGCGCCTGCTGCACCGGACCACGCGCAAG
CTCAGCCTGACGGAAGAAGGCGCACGCCTGTTCGAGCTGGCCGCGCCGGGCATGCGCCAGCTCGACGAAGCGCTCGAGCA
GGTCCGCAGCAGCAAGAGCGACAACGACGGTCTGATCCGCCTGACCGCTCCGCCGTCGCTCGGCAGCCGCGTGCTGGTCC
CGCTGGTGCGGGGCTTTCGCGAACAATACCCCCGCATCACCTTCGATGTAGTGCTGAGCGACCTCTTCACCGACCTGGTC
GAAGCCAAGATCGACGTCGGCTTCCGCGTCGGCACCAGCCCCGGCCAGAACCTGGTGGCGCGGCGGCTGTGCGACCTGCC
GCTGGTCATCTGCGCGGCGCCGGATTACCTGGCGCGGCACGGCGAGCCGGCCACCCTCGACGACTTGCTGCAGCACCAGT
GCACCGGCTTCCGCCGCCCCGCGACCGGGCGCATGGTGCCGTGGGAGCTGCAGGTGGACGGCGACCTGATCTACCAGGAG
GTGCCTGCCGTGGCGAGCTTCAATGACGTGGAAACCGAGGTCGAAGCGGTGCGCGCCGGCATGGGCATCGGCCAGCTGCC
CGCCTACATGATCCACGCCGACCTCGTGAGCGGGCGGCTGAAGGCGATCCTGCCGGGGTACAGCAGCAGCAATGTCGGCA
TGTACATGTACTACCCGCATCGCAGCCAGATGCCGGTGCGGGTCCGGCGCTTCATCGACTTCGTGGTGGAAGCGGGCCGG
GGCGCGGAGCAGTCGCTGTCACGGCTGGTCGGGGTCGTGACCTGA

Upstream 100 bases:

>100_bases
ATACCGCCAGGGCTGTGCATGCATTGCGAGCTGAAGTAGACGCCTCTGCCCGCTCAATCCGCTCTGTTCGCTCTATCCGC
AATTCACAGGCACGGGGTCT

Downstream 100 bases:

>100_bases
GCCTGCTACCCCGCAGCACAGACAACCAGAAGTTGCTATTGAAACGCCATTCCACTCTCTAGTGCGACGTTCGCTCCACG
CCTAAATTGGTCTCAACGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAAHARRLSPNRHYDGGILHHPLPVMDKARVLTLFLGVVRAGSFHRAAVEAGVTPQAASKAVRTLEDHLGVRLLHRTTRK
LSLTEEGARLFELAAPGMRQLDEALEQVRSSKSDNDGLIRLTAPPSLGSRVLVPLVRGFREQYPRITFDVVLSDLFTDLV
EAKIDVGFRVGTSPGQNLVARRLCDLPLVICAAPDYLARHGEPATLDDLLQHQCTGFRRPATGRMVPWELQVDGDLIYQE
VPAVASFNDVETEVEAVRAGMGIGQLPAYMIHADLVSGRLKAILPGYSSSNVGMYMYYPHRSQMPVRVRRFIDFVVEAGR
GAEQSLSRLVGVVT

Sequences:

>Translated_334_residues
MAAHARRLSPNRHYDGGILHHPLPVMDKARVLTLFLGVVRAGSFHRAAVEAGVTPQAASKAVRTLEDHLGVRLLHRTTRK
LSLTEEGARLFELAAPGMRQLDEALEQVRSSKSDNDGLIRLTAPPSLGSRVLVPLVRGFREQYPRITFDVVLSDLFTDLV
EAKIDVGFRVGTSPGQNLVARRLCDLPLVICAAPDYLARHGEPATLDDLLQHQCTGFRRPATGRMVPWELQVDGDLIYQE
VPAVASFNDVETEVEAVRAGMGIGQLPAYMIHADLVSGRLKAILPGYSSSNVGMYMYYPHRSQMPVRVRRFIDFVVEAGR
GAEQSLSRLVGVVT
>Mature_333_residues
AAHARRLSPNRHYDGGILHHPLPVMDKARVLTLFLGVVRAGSFHRAAVEAGVTPQAASKAVRTLEDHLGVRLLHRTTRKL
SLTEEGARLFELAAPGMRQLDEALEQVRSSKSDNDGLIRLTAPPSLGSRVLVPLVRGFREQYPRITFDVVLSDLFTDLVE
AKIDVGFRVGTSPGQNLVARRLCDLPLVICAAPDYLARHGEPATLDDLLQHQCTGFRRPATGRMVPWELQVDGDLIYQEV
PAVASFNDVETEVEAVRAGMGIGQLPAYMIHADLVSGRLKAILPGYSSSNVGMYMYYPHRSQMPVRVRRFIDFVVEAGRG
AEQSLSRLVGVVT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=38.9830508474576, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=32.9861111111111, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=29.3103448275862, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=28.6219081272085, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789639, Length=302, Percent_Identity=29.1390728476821, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=28.6689419795222, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=28.4697508896797, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788706, Length=181, Percent_Identity=28.7292817679558, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=24.7491638795987, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=25, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=192, Percent_Identity=32.8125, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786448, Length=279, Percent_Identity=25.089605734767, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082132, Length=311, Percent_Identity=25.08038585209, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788748, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI157672245, Length=145, Percent_Identity=29.6551724137931, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36760; Mature: 36629

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHARRLSPNRHYDGGILHHPLPVMDKARVLTLFLGVVRAGSFHRAAVEAGVTPQAASK
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
AVRTLEDHLGVRLLHRTTRKLSLTEEGARLFELAAPGMRQLDEALEQVRSSKSDNDGLIR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEE
LTAPPSLGSRVLVPLVRGFREQYPRITFDVVLSDLFTDLVEAKIDVGFRVGTSPGQNLVA
EECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
RRLCDLPLVICAAPDYLARHGEPATLDDLLQHQCTGFRRPATGRMVPWELQVDGDLIYQE
HHHHCCCEEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHH
VPAVASFNDVETEVEAVRAGMGIGQLPAYMIHADLVSGRLKAILPGYSSSNVGMYMYYPH
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEEECCC
RSQMPVRVRRFIDFVVEAGRGAEQSLSRLVGVVT
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAHARRLSPNRHYDGGILHHPLPVMDKARVLTLFLGVVRAGSFHRAAVEAGVTPQAASK
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHH
AVRTLEDHLGVRLLHRTTRKLSLTEEGARLFELAAPGMRQLDEALEQVRSSKSDNDGLIR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEE
LTAPPSLGSRVLVPLVRGFREQYPRITFDVVLSDLFTDLVEAKIDVGFRVGTSPGQNLVA
EECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHH
RRLCDLPLVICAAPDYLARHGEPATLDDLLQHQCTGFRRPATGRMVPWELQVDGDLIYQE
HHHHCCCEEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHH
VPAVASFNDVETEVEAVRAGMGIGQLPAYMIHADLVSGRLKAILPGYSSSNVGMYMYYPH
CCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCCCEEEEECCC
RSQMPVRVRRFIDFVVEAGRGAEQSLSRLVGVVT
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]