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The map label for this gene is xdhC2 [H]

Identifier: 116695832

GI number: 116695832

Start: 2143346

End: 2143879

Strand: Direct

Name: xdhC2 [H]

Synonym: H16_B1896

Alternate gene names: 116695832

Gene position: 2143346-2143879 (Clockwise)

Preceding gene: 116695829

Following gene: 116695833

Centisome position: 73.59

GC content: 64.98

Gene sequence:

>534_bases
ATGTCCAGTTCTGTTCGTTCCGACGCAAGCCAACCACAGCCTGGCGATAGCTACGGCTCAACCCGCATGCCGCTGTGCCT
GACGGTCAACGGCACGCTGCATCGCCTCGATATCGATCCGCGCGAATCCCTGCTTGACGTACTGCGCGAGCGCCTGGACC
TCACGGGCACGAAGAAGGGCTGCAACCAGGGCGCGTGCGGGGCCTGCACGGTGCTGGTGGACGGGCGCCGGATCAACGCC
TGCCTGGCTTTGGCCGCCATGTACAACGACGCCCACGTGAGCACGATCGAAGGCCTGTCGTCGGCCGACGGCGAGCTGCA
TCCGCTACAGGCCGCATTTATCGCGCACGATGGCTTCCAATGCGGATTCTGTACGGCAGGCCAGATCATGTCCGGCGTCG
CCTGCATCAATGAGGGTCATGCCACCTCCGCCGACGATGTGCGCTTCTGGATGAGCGGCAATATCTGCCGTTGCGGGGCT
TACCCGGGGGTCGTCGCGGCGATCGCCGAGGTCGGCGGGAGGATGCTGCCATGA

Upstream 100 bases:

>100_bases
TCGTTCCGGCAGTTCGCTGCCGAAGCTGGCGCAGGCCCGGGCGAAGTCCCTGTCCCCAACCGCCCGAATCATCCGGGCTA
TGCAAAGAGGAATGTCGACT

Downstream 100 bases:

>100_bases
TCCCGTTCACACTGCAGAAAGCCGGCTCGGAAGCTGAAGCGCTGGCGGCGGCCGCGGCCGGGGCCCGCTTCATCGCCGGC
GGCACCACGCTGGCGGACCT

Product: putative xanthine dehydrogenase subunit,iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSSSVRSDASQPQPGDSYGSTRMPLCLTVNGTLHRLDIDPRESLLDVLRERLDLTGTKKGCNQGACGACTVLVDGRRINA
CLALAAMYNDAHVSTIEGLSSADGELHPLQAAFIAHDGFQCGFCTAGQIMSGVACINEGHATSADDVRFWMSGNICRCGA
YPGVVAAIAEVGGRMLP

Sequences:

>Translated_177_residues
MSSSVRSDASQPQPGDSYGSTRMPLCLTVNGTLHRLDIDPRESLLDVLRERLDLTGTKKGCNQGACGACTVLVDGRRINA
CLALAAMYNDAHVSTIEGLSSADGELHPLQAAFIAHDGFQCGFCTAGQIMSGVACINEGHATSADDVRFWMSGNICRCGA
YPGVVAAIAEVGGRMLP
>Mature_176_residues
SSSVRSDASQPQPGDSYGSTRMPLCLTVNGTLHRLDIDPRESLLDVLRERLDLTGTKKGCNQGACGACTVLVDGRRINAC
LALAAMYNDAHVSTIEGLSSADGELHPLQAAFIAHDGFQCGFCTAGQIMSGVACINEGHATSADDVRFWMSGNICRCGAY
PGVVAAIAEVGGRMLP

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=133, Percent_Identity=37.593984962406, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI71773480, Length=141, Percent_Identity=38.2978723404255, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=55.952380952381, Blast_Score=190, Evalue=5e-50,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=38.4615384615385, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=161, Percent_Identity=37.2670807453416, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=169, Percent_Identity=33.1360946745562, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=32.0261437908497, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737937, Length=148, Percent_Identity=40.5405405405405, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=34.8387096774194, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=33.1168831168831, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=32.5, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=32.5, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=31.4102564102564, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 18548; Mature: 18417

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSVRSDASQPQPGDSYGSTRMPLCLTVNGTLHRLDIDPRESLLDVLRERLDLTGTKKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCCCCC
CNQGACGACTVLVDGRRINACLALAAMYNDAHVSTIEGLSSADGELHPLQAAFIAHDGFQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHEEEEEECCCCC
CGFCTAGQIMSGVACINEGHATSADDVRFWMSGNICRCGAYPGVVAAIAEVGGRMLP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SSSVRSDASQPQPGDSYGSTRMPLCLTVNGTLHRLDIDPRESLLDVLRERLDLTGTKKG
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCCCCC
CNQGACGACTVLVDGRRINACLALAAMYNDAHVSTIEGLSSADGELHPLQAAFIAHDGFQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHEEEEEECCCCC
CGFCTAGQIMSGVACINEGHATSADDVRFWMSGNICRCGAYPGVVAAIAEVGGRMLP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]