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The map label for this gene is glcD [H]

Identifier: 116695763

GI number: 116695763

Start: 2064789

End: 2066222

Strand: Direct

Name: glcD [H]

Synonym: H16_B1827

Alternate gene names: 116695763

Gene position: 2064789-2066222 (Clockwise)

Preceding gene: 116695760

Following gene: 116695764

Centisome position: 70.89

GC content: 68.34

Gene sequence:

>1434_bases
ATGTCACTTGTATTGAAGCTGAAAGACCTGTTGGGACCCGATGCGGTTCTCACCGAACCCGCGGACGTAGCCGCCTACAT
CGAGGACTGGCGCGGCCGTTATAAGGGCCCGGCGCTGTGCGTGGTGCTGCCGGCCTCCACCGCGCAAGTCGCCGCGGTGG
TGCAGGCCGCGGTCCAGGCCAGCGTGCCCGTGCTGCCGCAAGGCGGCAATACCAGCCTGTGCGGCGGCGCGGTGCCGGCC
CCGGACGGCACGCCGCCCATCGTCATCAGCCTGGCACGCATGCGGCGCATCCGCGCCATCGATGCGGCCAACAACTCGAT
GGAAGTCGAGGCAGGCTGCGTGCTGGCCGCGATCCAGCAGGCGGCGGCGGAACAGGGGCGCCTCTATCCCGTGAGCCTGG
GCGCCGAAGGCTCCTGCCAGATCGGCGGCAATATCGCCACCAATGCGGGCGGCACCGGCGTGCTGCGCTATGGCAACACC
CGCGACAACGTGCTCGGCCTTGAAGTGGTCCTGCCCGACGGCCAGGTCTGGAACGGCCTGTACCGCTTGCGCAAGAACAA
CACCGGCCTCGATCTCAAGCACCTGTTTATCGGCTCCGAAGGCACGCTGGGCGTGATCACCGCCGCCACGCTCAAGCTGC
ACCCGCTGCCCACCGCGCACGCCATGGCGTGGCTGGCGGTGAGCACGCCGCAGGCGGCGCTGGAGATGCTGGGACGCTTC
CAGCAGCGCTGTGGCGCCACCCTGTCCGCGTTTGAAATGCTCAATGACGTGCAGTTGCAGATCGTGCTCGATCACGTGCC
CGGCCGCCGTGCGCCGTTGCCTGCCAGCCATCCCTGGCACGTGCTGGTGGAACTTGCCGACACCGGCCGGCGCGAGCTGC
TCGACCAGGTGCTGCAGGAAGTGCTGGAGCAAGGCGTGGCCGAAGGCCTGGTCGACGATGCCGTGGTGGCCGCCAGCGGC
GCGCAGCGCGAAGCCATGTGGCAGGTGCGGCATAGCGTCTCCGAAGGCAACAAGAAGGCGGGCCTGGGCCTGAACACCGA
TTGCGCCGTGCCGGTCTCGGCGGTGCCGCAGTTCATTGAGCGCGCCACCGCGGCGGCGCATGCGGTCCTGCCGGACTTGC
CGATCATCGTCGTGGCCCACCTGGGCGATGGCAACGTCCACTTCATCCCGCTGGTGCCTTTCCCGCAGTGGCAAGCGCTG
CCAGAGCGCGATGCCGTGGCCGCCCGCATCAAGCACGCCATCGACCAGGTGGCCTACGAACTGGGCGGCACCTTCAGCGC
GGAACATGGCATCGGCCAGGTCCTGACCGAGGAAATGGCGCAGTTCAAGCCGGCGGTCGAGATCGCCATGATGCACGGCA
TCAAGCGCATGCTCGACCCGCGCGACCTGTTCAACCCCGGCCGGCTGCTGCCGTCCCCACCTTCCCAGCAATAA

Upstream 100 bases:

>100_bases
AAGTAATCGCATTGCGATTACTAGTATGTGGATTTCACCTATACATATGCTCATGACAATCGACTAGTATGGCTTCAATC
GAGCACGAGGGCACAAGGCG

Downstream 100 bases:

>100_bases
CGGCAATCAAGGAGCTCGCATGAACGACCACAGCCCCATCAACTCTTCTCGCCGGCGTGCCCTCAAGGTCGCCGCTGCCG
GCCTTGGCACGCTTGCCGCG

Product: FAD/FMN-containing dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSLVLKLKDLLGPDAVLTEPADVAAYIEDWRGRYKGPALCVVLPASTAQVAAVVQAAVQASVPVLPQGGNTSLCGGAVPA
PDGTPPIVISLARMRRIRAIDAANNSMEVEAGCVLAAIQQAAAEQGRLYPVSLGAEGSCQIGGNIATNAGGTGVLRYGNT
RDNVLGLEVVLPDGQVWNGLYRLRKNNTGLDLKHLFIGSEGTLGVITAATLKLHPLPTAHAMAWLAVSTPQAALEMLGRF
QQRCGATLSAFEMLNDVQLQIVLDHVPGRRAPLPASHPWHVLVELADTGRRELLDQVLQEVLEQGVAEGLVDDAVVAASG
AQREAMWQVRHSVSEGNKKAGLGLNTDCAVPVSAVPQFIERATAAAHAVLPDLPIIVVAHLGDGNVHFIPLVPFPQWQAL
PERDAVAARIKHAIDQVAYELGGTFSAEHGIGQVLTEEMAQFKPAVEIAMMHGIKRMLDPRDLFNPGRLLPSPPSQQ

Sequences:

>Translated_477_residues
MSLVLKLKDLLGPDAVLTEPADVAAYIEDWRGRYKGPALCVVLPASTAQVAAVVQAAVQASVPVLPQGGNTSLCGGAVPA
PDGTPPIVISLARMRRIRAIDAANNSMEVEAGCVLAAIQQAAAEQGRLYPVSLGAEGSCQIGGNIATNAGGTGVLRYGNT
RDNVLGLEVVLPDGQVWNGLYRLRKNNTGLDLKHLFIGSEGTLGVITAATLKLHPLPTAHAMAWLAVSTPQAALEMLGRF
QQRCGATLSAFEMLNDVQLQIVLDHVPGRRAPLPASHPWHVLVELADTGRRELLDQVLQEVLEQGVAEGLVDDAVVAASG
AQREAMWQVRHSVSEGNKKAGLGLNTDCAVPVSAVPQFIERATAAAHAVLPDLPIIVVAHLGDGNVHFIPLVPFPQWQAL
PERDAVAARIKHAIDQVAYELGGTFSAEHGIGQVLTEEMAQFKPAVEIAMMHGIKRMLDPRDLFNPGRLLPSPPSQQ
>Mature_476_residues
SLVLKLKDLLGPDAVLTEPADVAAYIEDWRGRYKGPALCVVLPASTAQVAAVVQAAVQASVPVLPQGGNTSLCGGAVPAP
DGTPPIVISLARMRRIRAIDAANNSMEVEAGCVLAAIQQAAAEQGRLYPVSLGAEGSCQIGGNIATNAGGTGVLRYGNTR
DNVLGLEVVLPDGQVWNGLYRLRKNNTGLDLKHLFIGSEGTLGVITAATLKLHPLPTAHAMAWLAVSTPQAALEMLGRFQ
QRCGATLSAFEMLNDVQLQIVLDHVPGRRAPLPASHPWHVLVELADTGRRELLDQVLQEVLEQGVAEGLVDDAVVAASGA
QREAMWQVRHSVSEGNKKAGLGLNTDCAVPVSAVPQFIERATAAAHAVLPDLPIIVVAHLGDGNVHFIPLVPFPQWQALP
ERDAVAARIKHAIDQVAYELGGTFSAEHGIGQVLTEEMAQFKPAVEIAMMHGIKRMLDPRDLFNPGRLLPSPPSQQ

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=466, Percent_Identity=34.1201716738197, Blast_Score=252, Evalue=5e-67,
Organism=Homo sapiens, GI37595756, Length=486, Percent_Identity=32.5102880658436, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI37595754, Length=509, Percent_Identity=31.041257367387, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI4501993, Length=223, Percent_Identity=29.1479820627803, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1789351, Length=475, Percent_Identity=29.8947368421053, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787977, Length=521, Percent_Identity=24.1842610364683, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI48994907, Length=501, Percent_Identity=21.9560878243513, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534361, Length=475, Percent_Identity=31.5789473684211, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71992373, Length=482, Percent_Identity=29.045643153527, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=482, Percent_Identity=28.2157676348548, Blast_Score=161, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI71992392, Length=372, Percent_Identity=31.4516129032258, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17556096, Length=465, Percent_Identity=23.2258064516129, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320023, Length=477, Percent_Identity=32.7044025157233, Blast_Score=276, Evalue=7e-75,
Organism=Saccharomyces cerevisiae, GI6320764, Length=480, Percent_Identity=30.2083333333333, Blast_Score=246, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6320027, Length=451, Percent_Identity=27.0509977827051, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI18921117, Length=472, Percent_Identity=32.4152542372881, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24639277, Length=472, Percent_Identity=32.4152542372881, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24639275, Length=472, Percent_Identity=32.4152542372881, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24653753, Length=218, Percent_Identity=29.3577981651376, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50500; Mature: 50369

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVLKLKDLLGPDAVLTEPADVAAYIEDWRGRYKGPALCVVLPASTAQVAAVVQAAVQA
CCEEEEEHHHCCCCCEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
SVPVLPQGGNTSLCGGAVPAPDGTPPIVISLARMRRIRAIDAANNSMEVEAGCVLAAIQQ
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
AAAEQGRLYPVSLGAEGSCQIGGNIATNAGGTGVLRYGNTRDNVLGLEVVLPDGQVWNGL
HHHHCCCEEEEEECCCCCEEECCEEEECCCCCEEEEECCCCCCEEEEEEEECCCHHHHHH
YRLRKNNTGLDLKHLFIGSEGTLGVITAATLKLHPLPTAHAMAWLAVSTPQAALEMLGRF
HHHHCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHEEEEECCHHHHHHHHHHH
QQRCGATLSAFEMLNDVQLQIVLDHVPGRRAPLPASHPWHVLVELADTGRRELLDQVLQE
HHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHH
VLEQGVAEGLVDDAVVAASGAQREAMWQVRHSVSEGNKKAGLGLNTDCAVPVSAVPQFIE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RATAAAHAVLPDLPIIVVAHLGDGNVHFIPLVPFPQWQALPERDAVAARIKHAIDQVAYE
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGGTFSAEHGIGQVLTEEMAQFKPAVEIAMMHGIKRMLDPRDLFNPGRLLPSPPSQQ
HCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLVLKLKDLLGPDAVLTEPADVAAYIEDWRGRYKGPALCVVLPASTAQVAAVVQAAVQA
CEEEEEHHHCCCCCEECCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
SVPVLPQGGNTSLCGGAVPAPDGTPPIVISLARMRRIRAIDAANNSMEVEAGCVLAAIQQ
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
AAAEQGRLYPVSLGAEGSCQIGGNIATNAGGTGVLRYGNTRDNVLGLEVVLPDGQVWNGL
HHHHCCCEEEEEECCCCCEEECCEEEECCCCCEEEEECCCCCCEEEEEEEECCCHHHHHH
YRLRKNNTGLDLKHLFIGSEGTLGVITAATLKLHPLPTAHAMAWLAVSTPQAALEMLGRF
HHHHCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHEEEEECCHHHHHHHHHHH
QQRCGATLSAFEMLNDVQLQIVLDHVPGRRAPLPASHPWHVLVELADTGRRELLDQVLQE
HHHHCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHH
VLEQGVAEGLVDDAVVAASGAQREAMWQVRHSVSEGNKKAGLGLNTDCAVPVSAVPQFIE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
RATAAAHAVLPDLPIIVVAHLGDGNVHFIPLVPFPQWQALPERDAVAARIKHAIDQVAYE
HHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGGTFSAEHGIGQVLTEEMAQFKPAVEIAMMHGIKRMLDPRDLFNPGRLLPSPPSQQ
HCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]