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The map label for this gene is paaG [H]

Identifier: 116695709

GI number: 116695709

Start: 2012933

End: 2013709

Strand: Direct

Name: paaG [H]

Synonym: H16_B1773

Alternate gene names: 116695709

Gene position: 2012933-2013709 (Clockwise)

Preceding gene: 116695704

Following gene: 116695712

Centisome position: 69.11

GC content: 63.06

Gene sequence:

>777_bases
ATGACCCCCGAAATCCGCATTGACCTCACCGGCGGCGTGCTGACCATGACGCTTGCGCGGCCGGACAAGATGAACGCCTT
GACGAACGAGATGTACGGCGCACTTGCCGACACCATCGAGCAGGCACAGCAGGACCGGGCTATCCGGGTATTGCTGCTGC
AGGGGGACGGGGACAGCTTTACGGCCGGCAATGATCTCGGCGAATTCGCGGCGATCGCGTCGGGAAATGGCCCCAGCGAA
CGTCACGTGCATCGCTTCCTGCGCGCCCTTGCCAATTCGACCGTACCGATTGTCGCCGCGGTCAATGGCAAGGCCGTCGG
CGTCGGGACCACCATGCTGCTGCATTGTGATTACGTGGTGCTCGGCCAGGACGCGCAACTGATCACGCCTTTCGTCAATC
TCGCCTTGGTTCCCGAAGCGGCTTCGAGTTACCTGCTGCCGCTGCGGATCGGGCACGTCAGGGCTTTCGAGATGTTCGCG
CTGGGCGAGCCGCTTGACGCGCAAACGGCCTTGGCATGGGGCATCGCGAACAAGGTTTGCGCCAATGACCAGCTGCGCAC
GGATGCGCGCCGGATGGCCGAGAAGATTGCCGCCAGGCCGGCCGGCTCCCTGAGCGCAATGAAACAGCTCATGCGCAATG
CGGAAAAACTGGTTTCGCAGATGAACAGCGAAAGCGCCAGGTTCGAGGAGCGGCTGGCCAGTGCGGAAGCCCGGGAAGCA
TTCTCGGCCTTCGCCGAAAAGCGCAAACCAGACTTCACCAGGGTTGCCGCGCAGTGA

Upstream 100 bases:

>100_bases
CAACCGTTTACTTCGCACACGAACTATCTATATACTTCGCATGCGAACTTAATCGCGATGCCTGCACGGCAGCGTGCAAC
TCTCACCTGGAGACCGACCA

Downstream 100 bases:

>100_bases
GTCGACTGCCTCGCTCTCCGGCCGCTGCGAGGCTACACCTCGCCCTCGTCCGCGGCCGGAAACTTTGTCTGGAGGCTGGT
CAGCCAGCGCGCCACCACGT

Product: enoyl-CoA hydratase/carnithine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTPEIRIDLTGGVLTMTLARPDKMNALTNEMYGALADTIEQAQQDRAIRVLLLQGDGDSFTAGNDLGEFAAIASGNGPSE
RHVHRFLRALANSTVPIVAAVNGKAVGVGTTMLLHCDYVVLGQDAQLITPFVNLALVPEAASSYLLPLRIGHVRAFEMFA
LGEPLDAQTALAWGIANKVCANDQLRTDARRMAEKIAARPAGSLSAMKQLMRNAEKLVSQMNSESARFEERLASAEAREA
FSAFAEKRKPDFTRVAAQ

Sequences:

>Translated_258_residues
MTPEIRIDLTGGVLTMTLARPDKMNALTNEMYGALADTIEQAQQDRAIRVLLLQGDGDSFTAGNDLGEFAAIASGNGPSE
RHVHRFLRALANSTVPIVAAVNGKAVGVGTTMLLHCDYVVLGQDAQLITPFVNLALVPEAASSYLLPLRIGHVRAFEMFA
LGEPLDAQTALAWGIANKVCANDQLRTDARRMAEKIAARPAGSLSAMKQLMRNAEKLVSQMNSESARFEERLASAEAREA
FSAFAEKRKPDFTRVAAQ
>Mature_257_residues
TPEIRIDLTGGVLTMTLARPDKMNALTNEMYGALADTIEQAQQDRAIRVLLLQGDGDSFTAGNDLGEFAAIASGNGPSER
HVHRFLRALANSTVPIVAAVNGKAVGVGTTMLLHCDYVVLGQDAQLITPFVNLALVPEAASSYLLPLRIGHVRAFEMFAL
GEPLDAQTALAWGIANKVCANDQLRTDARRMAEKIAARPAGSLSAMKQLMRNAEKLVSQMNSESARFEERLASAEAREAF
SAFAEKRKPDFTRVAAQ

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI260275230, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI260274832, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI194097323, Length=239, Percent_Identity=28.4518828451883, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI31542718, Length=249, Percent_Identity=28.5140562248996, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI25453481, Length=241, Percent_Identity=25.3112033195021, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI51538573, Length=241, Percent_Identity=25.3112033195021, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4757968, Length=241, Percent_Identity=25.3112033195021, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI49355787, Length=241, Percent_Identity=25.3112033195021, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116235487, Length=199, Percent_Identity=29.6482412060301, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4757966, Length=166, Percent_Identity=28.3132530120482, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI51538581, Length=166, Percent_Identity=28.3132530120482, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI68989263, Length=187, Percent_Identity=28.8770053475936, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4502327, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI221136756, Length=160, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI221136753, Length=160, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI221307494, Length=160, Percent_Identity=27.5, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI20127408, Length=181, Percent_Identity=26.5193370165746, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=251, Percent_Identity=37.0517928286853, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787659, Length=244, Percent_Identity=33.1967213114754, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=29.9242424242424, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788597, Length=261, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082183, Length=240, Percent_Identity=24.5833333333333, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788682, Length=208, Percent_Identity=25.9615384615385, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17535521, Length=247, Percent_Identity=33.6032388663968, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17554946, Length=264, Percent_Identity=31.0606060606061, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=243, Percent_Identity=30.4526748971193, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17549921, Length=204, Percent_Identity=32.3529411764706, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=248, Percent_Identity=27.4193548387097, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=241, Percent_Identity=27.3858921161826, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=26.1111111111111, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17534483, Length=204, Percent_Identity=25.4901960784314, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323314, Length=200, Percent_Identity=27, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129971, Length=260, Percent_Identity=31.9230769230769, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24653477, Length=260, Percent_Identity=31.9230769230769, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24654903, Length=250, Percent_Identity=26.8, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24653139, Length=253, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922422, Length=252, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27812; Mature: 27681

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEIRIDLTGGVLTMTLARPDKMNALTNEMYGALADTIEQAQQDRAIRVLLLQGDGDSF
CCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
TAGNDLGEFAAIASGNGPSERHVHRFLRALANSTVPIVAAVNGKAVGVGTTMLLHCDYVV
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCEEEEEECEEE
LGQDAQLITPFVNLALVPEAASSYLLPLRIGHVRAFEMFALGEPLDAQTALAWGIANKVC
ECCCCHHHHHHHHHEECCCCCCCEEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ANDQLRTDARRMAEKIAARPAGSLSAMKQLMRNAEKLVSQMNSESARFEERLASAEAREA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FSAFAEKRKPDFTRVAAQ
HHHHHHHCCCCHHHHCCC
>Mature Secondary Structure 
TPEIRIDLTGGVLTMTLARPDKMNALTNEMYGALADTIEQAQQDRAIRVLLLQGDGDSF
CCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
TAGNDLGEFAAIASGNGPSERHVHRFLRALANSTVPIVAAVNGKAVGVGTTMLLHCDYVV
CCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEECCCEEEEEECEEE
LGQDAQLITPFVNLALVPEAASSYLLPLRIGHVRAFEMFALGEPLDAQTALAWGIANKVC
ECCCCHHHHHHHHHEECCCCCCCEEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
ANDQLRTDARRMAEKIAARPAGSLSAMKQLMRNAEKLVSQMNSESARFEERLASAEAREA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
FSAFAEKRKPDFTRVAAQ
HHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]