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The map label for this gene is degP [H]

Identifier: 116695551

GI number: 116695551

Start: 1820960

End: 1821907

Strand: Direct

Name: degP [H]

Synonym: H16_B1612

Alternate gene names: 116695551

Gene position: 1820960-1821907 (Clockwise)

Preceding gene: 116695543

Following gene: 116695552

Centisome position: 62.52

GC content: 67.3

Gene sequence:

>948_bases
ATGAGACGGGTAACGATCTACGGATGGGTCTCGGCAGCGGTGGCGCTGGTGCTCGCGGCGGTCGTTGGCTCTGCCTGGCT
GTTGCAGCCGACGCCGCGCGTCCTCAAGCAAGCCGACATCGACTCCGCCGTGCTGCACACGCTGGAAACCAAGCGCCTGC
CTTCGCGCACAGCCAGGGCGGCAGAGGCGGTTCGCGAGTCGGTGGTGGAAGTTCGCAGCTATGCGCCAGCCGAAAAGGCT
GCGGACAAGCCGAAGAAAGCGGCATCCGCCCCACACGCCAAGCGTGATCCCCCTGCCACACGCCGCAAGGCACCCCCCGA
ATCGGCTCCGCTATCCCCGCCGCCTTCGGGCGATGAACTCGCAAAAGGCGACCCACCGGGCAGCAAGGGCGAGTCCGGCG
GCAAGCGCACAGCCCGCCACATCGGTTCGGGGGTGGTCGTGACCGAAAGCGGCACCATTCTCACCAGCTACCACGTCGTC
GCCGACGCCCTGCGCCTGGAGGTCAGGTTCCACGACGGCCACACGGCCGAGGCCTCGGTTGTGCAGGCGTTCCCGGAGAA
AGACCTAGCCGTGATCCGGCCCAGTTCCATCCCCGACGACCTGCCGCCGGCGACGCTCGGTTCCAGCCGGAACCTCGCGC
CCGGCACTGAAGTCGTCGCGGTCGGCTTTCCGTTCGGCATCGGCCCGTCGGTGTCTGCCGGCGTGGTGTCGGGGCTCGAC
CGCAGGTTCGTCTTGCCGGACGGCAAGCGGGACCTGGACAAGCTCATCCAGTTCGACGCCGCCGCCAATCCGGGCAACTC
CGGCGGACCGCTGGTGAATCTGGATGGCGAGGTGGTAGGGATCGTCACCGCCATCCTCAACCCCAACCAGAGCGGCACTT
TCCTCGGCATCGGCTTTGCTGTCACGATCGAAAGCGCCGGCGCTTCCATCGGATCCTCTCCTTTCTAA

Upstream 100 bases:

>100_bases
GCATTTGCGGCCAGAGAAACTGCATGCACCTGCTCCTTGGCGCGTGGGTAAGACGATGGTACTGTATTTTTCACGGCGGG
ACGGGACCTCGGGAGCGGCA

Downstream 100 bases:

>100_bases
TCGCGGGGGCCTATGAACGACCAAACCCGGGGCGCAGTGGACAGCGCCGAATTGATGGAACGCCTGCTGTATGAGGTGAA
GCGCGTGGTGGTGGGGCAGG

Product: trypsin-like serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRRVTIYGWVSAAVALVLAAVVGSAWLLQPTPRVLKQADIDSAVLHTLETKRLPSRTARAAEAVRESVVEVRSYAPAEKA
ADKPKKAASAPHAKRDPPATRRKAPPESAPLSPPPSGDELAKGDPPGSKGESGGKRTARHIGSGVVVTESGTILTSYHVV
ADALRLEVRFHDGHTAEASVVQAFPEKDLAVIRPSSIPDDLPPATLGSSRNLAPGTEVVAVGFPFGIGPSVSAGVVSGLD
RRFVLPDGKRDLDKLIQFDAAANPGNSGGPLVNLDGEVVGIVTAILNPNQSGTFLGIGFAVTIESAGASIGSSPF

Sequences:

>Translated_315_residues
MRRVTIYGWVSAAVALVLAAVVGSAWLLQPTPRVLKQADIDSAVLHTLETKRLPSRTARAAEAVRESVVEVRSYAPAEKA
ADKPKKAASAPHAKRDPPATRRKAPPESAPLSPPPSGDELAKGDPPGSKGESGGKRTARHIGSGVVVTESGTILTSYHVV
ADALRLEVRFHDGHTAEASVVQAFPEKDLAVIRPSSIPDDLPPATLGSSRNLAPGTEVVAVGFPFGIGPSVSAGVVSGLD
RRFVLPDGKRDLDKLIQFDAAANPGNSGGPLVNLDGEVVGIVTAILNPNQSGTFLGIGFAVTIESAGASIGSSPF
>Mature_315_residues
MRRVTIYGWVSAAVALVLAAVVGSAWLLQPTPRVLKQADIDSAVLHTLETKRLPSRTARAAEAVRESVVEVRSYAPAEKA
ADKPKKAASAPHAKRDPPATRRKAPPESAPLSPPPSGDELAKGDPPGSKGESGGKRTARHIGSGVVVTESGTILTSYHVV
ADALRLEVRFHDGHTAEASVVQAFPEKDLAVIRPSSIPDDLPPATLGSSRNLAPGTEVVAVGFPFGIGPSVSAGVVSGLD
RRFVLPDGKRDLDKLIQFDAAANPGNSGGPLVNLDGEVVGIVTAILNPNQSGTFLGIGFAVTIESAGASIGSSPF

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=166, Percent_Identity=41.566265060241, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24308541, Length=165, Percent_Identity=40, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI22129776, Length=169, Percent_Identity=40.2366863905325, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7019477, Length=166, Percent_Identity=41.566265060241, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786356, Length=162, Percent_Identity=41.358024691358, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789629, Length=162, Percent_Identity=39.5061728395062, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789630, Length=181, Percent_Identity=34.8066298342541, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646839, Length=166, Percent_Identity=39.1566265060241, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 32523; Mature: 32523

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVTIYGWVSAAVALVLAAVVGSAWLLQPTPRVLKQADIDSAVLHTLETKRLPSRTARA
CCEEEEEHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
AEAVRESVVEVRSYAPAEKAADKPKKAASAPHAKRDPPATRRKAPPESAPLSPPPSGDEL
HHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
AKGDPPGSKGESGGKRTARHIGSGVVVTESGTILTSYHVVADALRLEVRFHDGHTAEASV
CCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCEEEHHHHHHHEEEEEEEECCCCCCHHHH
VQAFPEKDLAVIRPSSIPDDLPPATLGSSRNLAPGTEVVAVGFPFGIGPSVSAGVVSGLD
HHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCC
RRFVLPDGKRDLDKLIQFDAAANPGNSGGPLVNLDGEVVGIVTAILNPNQSGTFLGIGFA
CEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHHCCCCCCCCEEEEEEE
VTIESAGASIGSSPF
EEEECCCCCCCCCCC
>Mature Secondary Structure
MRRVTIYGWVSAAVALVLAAVVGSAWLLQPTPRVLKQADIDSAVLHTLETKRLPSRTARA
CCEEEEEHHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
AEAVRESVVEVRSYAPAEKAADKPKKAASAPHAKRDPPATRRKAPPESAPLSPPPSGDEL
HHHHHHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
AKGDPPGSKGESGGKRTARHIGSGVVVTESGTILTSYHVVADALRLEVRFHDGHTAEASV
CCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCEEEHHHHHHHEEEEEEEECCCCCCHHHH
VQAFPEKDLAVIRPSSIPDDLPPATLGSSRNLAPGTEVVAVGFPFGIGPSVSAGVVSGLD
HHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCC
RRFVLPDGKRDLDKLIQFDAAANPGNSGGPLVNLDGEVVGIVTAILNPNQSGTFLGIGFA
CEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCEEEEEHHHCCCCCCCCEEEEEEE
VTIESAGASIGSSPF
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]