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The map label for this gene is ttuB [H]

Identifier: 116695489

GI number: 116695489

Start: 1738131

End: 1739489

Strand: Direct

Name: ttuB [H]

Synonym: H16_B1548

Alternate gene names: 116695489

Gene position: 1738131-1739489 (Clockwise)

Preceding gene: 116695488

Following gene: 116695491

Centisome position: 59.68

GC content: 68.29

Gene sequence:

>1359_bases
ATGAGCCATCCGGTCTCAGGGGATCTTTCGTCCCTATCCAGCCTGACGTCCCCCACCCTGCCTCCCGCAGCACTGGCTGC
GCACGATGAGGATGCGCTCTACCGCAAGGTCTGGCTGCGCATCATCCCGTTCCTGTTCGTCTGCTACGTGGTGTCGTTCC
TGGACCGCATCAACATCGGCTTCGCCCAGTTGCAGATGAAGCAGGACCTGGGCTTCAGCGACGCCATGTACGGCCTGGGC
GCCGCGGTCTTCTACGTCGGCTACGTGCTGTGCGAAGTGCCCAGCAACATGCTGCTGGCGCGCTTTGGCGCACGGCGCAC
GTTCACGCGCATCATGGTGCTGTGGGGCCTGGCCTCGGTGGCGATGATGGGCGTCTCCACCCCGGCGCAGTTCTATACGC
TGCGCTTCCTGCTGGGCGTGTTCGAAGCCGGCTTCTTCCCCGGCATCGTGCTCTACCTGACCTACTGGTTCCCGGCGCGC
CGCCGCGCCGCGGTGATGGCGATCTTCTTTGCCGGCGTGGCGGTGGCGGGTGTGCTGGGCGGGCTGGTGTCCGGCTGGAT
CATGCGCGACATGGCCGGCGTGCTCGGGCTGCAGGGCTGGAAGTGGATGTTTGCGATCGAGGGCGCGCCCGCGGTGCTGC
TGGGCCTGCTGGCCGCGCGCTGCCTGGTTGATGGCCCGCAGCAGGCCAGCTGGCTGACCGACGGCGAACGTGCCCACCTG
GCGCGCGACACGGCCGCGCAAGCACATGCCGGCGGCCATTCGCTGCACGCGTTGCGGCAGGTTCTGCGCAACCCGCGCGT
GTACCTGTTCGCGTTTATCTATTTTTCGCTGACCTGTGGTTCGCTGGCGCTGAGCTTCTGGATGCCGCTGATGATCCGCG
ACTTCGGCATCACCGACGTGATGTCGGTCAGCCTGTATTCGGTGGTACCCAATGCCGTGGGCGCGGTCGGCCTGCTCCTG
ATCGCGCGCCACTCCGACCGCACCGGCGAGCGCCACCGCCACTTCCTGCTGTGCACGGCAGGCGGCGCGCTGGCCCTGGC
GGCGCTGACCCTGCACCTGCCCAGCCTGGCGCTGATGCTGGCCATCCTGTCGGTGGCCGCGGTGCTGATCTTTGCCGCGC
TGCCGGTGTTCTGGTCGCTGCCGCCCAGCTACCTGCCGGGCGCGGGCACGGCCGCCGGCATCGCCTTCATCAGCAGCATC
GGCATCACCAGCGGCATCGTCAGCCCGTGGGTGATTGGACAGATCAAGACCCGGACCGGCAGCCTGGACCATGCCCTCTA
CCTGCTGGCGGCGCTGCTGCTGGCCAGCGGCCTGGCCATGTGGCTGGGTGTGCCAAGGCAGCCCGCGCGGCCGGCCTGA

Upstream 100 bases:

>100_bases
TCCCGGCACCATCGCGGGCCAACGCGCGCAAGACGCTGCCCACTGGCGGAACCCTCCGGCTGCCCGCCGCCGCAGCCACC
ACCGTACGGAGACAACGTTC

Downstream 100 bases:

>100_bases
ACCGGGCCGCAGGCGTCTTCAAAACCGGAATGTCCGCACCCACGGGGTGCAGCGTTCAGTGGGATCGGCCGCAGGGGATG
ACGGAGGCGATTTCCTCGCG

Product: major facilitator superfamily transporter ACS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSHPVSGDLSSLSSLTSPTLPPAALAAHDEDALYRKVWLRIIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLG
AAVFYVGYVLCEVPSNMLLARFGARRTFTRIMVLWGLASVAMMGVSTPAQFYTLRFLLGVFEAGFFPGIVLYLTYWFPAR
RRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVLGLQGWKWMFAIEGAPAVLLGLLAARCLVDGPQQASWLTDGERAHL
ARDTAAQAHAGGHSLHALRQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVMSVSLYSVVPNAVGAVGLLL
IARHSDRTGERHRHFLLCTAGGALALAALTLHLPSLALMLAILSVAAVLIFAALPVFWSLPPSYLPGAGTAAGIAFISSI
GITSGIVSPWVIGQIKTRTGSLDHALYLLAALLLASGLAMWLGVPRQPARPA

Sequences:

>Translated_452_residues
MSHPVSGDLSSLSSLTSPTLPPAALAAHDEDALYRKVWLRIIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLG
AAVFYVGYVLCEVPSNMLLARFGARRTFTRIMVLWGLASVAMMGVSTPAQFYTLRFLLGVFEAGFFPGIVLYLTYWFPAR
RRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVLGLQGWKWMFAIEGAPAVLLGLLAARCLVDGPQQASWLTDGERAHL
ARDTAAQAHAGGHSLHALRQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVMSVSLYSVVPNAVGAVGLLL
IARHSDRTGERHRHFLLCTAGGALALAALTLHLPSLALMLAILSVAAVLIFAALPVFWSLPPSYLPGAGTAAGIAFISSI
GITSGIVSPWVIGQIKTRTGSLDHALYLLAALLLASGLAMWLGVPRQPARPA
>Mature_451_residues
SHPVSGDLSSLSSLTSPTLPPAALAAHDEDALYRKVWLRIIPFLFVCYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGA
AVFYVGYVLCEVPSNMLLARFGARRTFTRIMVLWGLASVAMMGVSTPAQFYTLRFLLGVFEAGFFPGIVLYLTYWFPARR
RAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVLGLQGWKWMFAIEGAPAVLLGLLAARCLVDGPQQASWLTDGERAHLA
RDTAAQAHAGGHSLHALRQVLRNPRVYLFAFIYFSLTCGSLALSFWMPLMIRDFGITDVMSVSLYSVVPNAVGAVGLLLI
ARHSDRTGERHRHFLLCTAGGALALAALTLHLPSLALMLAILSVAAVLIFAALPVFWSLPPSYLPGAGTAAGIAFISSIG
ITSGIVSPWVIGQIKTRTGSLDHALYLLAALLLASGLAMWLGVPRQPARPA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=390, Percent_Identity=37.1794871794872, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=23.0232558139535, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789515, Length=422, Percent_Identity=24.6445497630332, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367379, Length=376, Percent_Identity=24.2021276595745, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082320, Length=311, Percent_Identity=23.4726688102894, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082310, Length=342, Percent_Identity=23.9766081871345, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322025, Length=212, Percent_Identity=30.6603773584906, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321698, Length=341, Percent_Identity=21.9941348973607, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319876, Length=173, Percent_Identity=27.1676300578035, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=379, Percent_Identity=22.6912928759894, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=303, Percent_Identity=23.7623762376238, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=280, Percent_Identity=23.5714285714286, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=163, Percent_Identity=25.1533742331288, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24584153, Length=364, Percent_Identity=22.2527472527473, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48544; Mature: 48413

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SHPVSGDLSSLSSLTSPTLPPAALAAHDEDALYRKVWLRIIPFLFVCYVVSFLDRINIG
CCCCCCCHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC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CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]