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The map label for this gene is paaX [H]

Identifier: 116695307

GI number: 116695307

Start: 1525490

End: 1526428

Strand: Direct

Name: paaX [H]

Synonym: H16_B1364

Alternate gene names: 116695307

Gene position: 1525490-1526428 (Clockwise)

Preceding gene: 116695297

Following gene: 116695309

Centisome position: 52.38

GC content: 69.65

Gene sequence:

>939_bases
ATGGCGACGCCAGGCACAGATCCGGTTTCTCCCCGCGTGGCGCGGCTGGCACGCGGGCTGAAGCTGGGCGCCAATTCCAT
GCTGGTGACCTTGTTCGGCGATGTGGTGGCGCCGCGGCCGCAGGCCATCTGGCTGGGCAGCCTGATCCGGCTGGCGGCGC
CGTTCGGCATCAATGACCGGCTGGTGCGCACCGCCACCTTCCGCCTTACCGCCGACGACTGGCTGGCCGCGACCAGGATG
GGGCGGCGCAGCTACTACGGGCTGTCAGACGCCGGTTTGCAGCGTGTACTGCACGCTGGCAAGCGCATCTATGCGGGTGA
GGCATCCGAATGGGACGGCCGCTGGACCCTGGTGATGGTGCGCGGTGACGTACGCGCCACGGTCCGGCAGAAGCTGAAGC
GGGAATTGCTGTGGGAGGGCTTCGGCGCCATCGCGCCGGGGGTGATGGCCCACCCCCAAGCGGACCTCGCCTCGCTGCGC
GAAATCCTCCAGGCCGCACGCGCGCAGGACGATGTGGCGGTGATGGAAGCGAGCAGCCTCGAGGCGTTTTCCATCCGGCC
GCTGCAGGCGCTGATGCACCAGACCTTCAAGCTCGGCGACGTGGCCGCTGCCTGGCAGGCACTGCTGCGCCGCTTTGCGC
CGCTGGCCGAAGAGGCCGCCGGGCTTGCTCCGGCCGATGCTTTCTTCGTGCGGACGCTCCTGGTGCACGAATACCGGCGT
GTGCTGCTGCGCGACCCCAACCTGCCCGAAGCGATGCTGCCGCAAGACTGGCCCGGCCGCACCGCGCGCGGCTTGTGCCA
CACCCTGTACGGGGCGCTGCTAGACGCCAGCGAAGACTACCTGCACCGCGTGGTGGAAGCGGCGGACGGTTCGCTGCACG
ATGCCAACCGGAGCCTGCGCCTGCGCTTTGGGGCGGGCGCGCAGGCGGGCAACGATTAA

Upstream 100 bases:

>100_bases
GGTCTTGACCTGCATCAACATCGTCAGTTGCAACGGATGGTAGTGATACAATTTGATTCAATCAATCTGCATTTGTGTAT
CACTTCAGGGAGCGGGGCCG

Downstream 100 bases:

>100_bases
CCGGGCATCCGGGGAATCCCGGCTGCGCACCTGCGCATGGAATCACCCGTCCTTGAACAGGAAGCTGTAGGCGTTCAATG
CCGGTACCCCGCCCAGGTGT

Product: PaaX family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MATPGTDPVSPRVARLARGLKLGANSMLVTLFGDVVAPRPQAIWLGSLIRLAAPFGINDRLVRTATFRLTADDWLAATRM
GRRSYYGLSDAGLQRVLHAGKRIYAGEASEWDGRWTLVMVRGDVRATVRQKLKRELLWEGFGAIAPGVMAHPQADLASLR
EILQAARAQDDVAVMEASSLEAFSIRPLQALMHQTFKLGDVAAAWQALLRRFAPLAEEAAGLAPADAFFVRTLLVHEYRR
VLLRDPNLPEAMLPQDWPGRTARGLCHTLYGALLDASEDYLHRVVEAADGSLHDANRSLRLRFGAGAQAGND

Sequences:

>Translated_312_residues
MATPGTDPVSPRVARLARGLKLGANSMLVTLFGDVVAPRPQAIWLGSLIRLAAPFGINDRLVRTATFRLTADDWLAATRM
GRRSYYGLSDAGLQRVLHAGKRIYAGEASEWDGRWTLVMVRGDVRATVRQKLKRELLWEGFGAIAPGVMAHPQADLASLR
EILQAARAQDDVAVMEASSLEAFSIRPLQALMHQTFKLGDVAAAWQALLRRFAPLAEEAAGLAPADAFFVRTLLVHEYRR
VLLRDPNLPEAMLPQDWPGRTARGLCHTLYGALLDASEDYLHRVVEAADGSLHDANRSLRLRFGAGAQAGND
>Mature_311_residues
ATPGTDPVSPRVARLARGLKLGANSMLVTLFGDVVAPRPQAIWLGSLIRLAAPFGINDRLVRTATFRLTADDWLAATRMG
RRSYYGLSDAGLQRVLHAGKRIYAGEASEWDGRWTLVMVRGDVRATVRQKLKRELLWEGFGAIAPGVMAHPQADLASLRE
ILQAARAQDDVAVMEASSLEAFSIRPLQALMHQTFKLGDVAAAWQALLRRFAPLAEEAAGLAPADAFFVRTLLVHEYRRV
LLRDPNLPEAMLPQDWPGRTARGLCHTLYGALLDASEDYLHRVVEAADGSLHDANRSLRLRFGAGAQAGND

Specific function: Negative regulator of the paaZ and paaABCDEFGHIJK catabolic operons. Binds the consensus sequence 5'- WWTRTGATTCGYGWT-3'. Binding of paaX is specifically inhibited by phenylacetyl-coenzyme A [H]

COG id: COG3327

COG function: function code K; Phenylacetic acid-responsive transcriptional repressor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787666, Length=287, Percent_Identity=38.3275261324042, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012906
- InterPro:   IPR013225
- InterPro:   IPR011965 [H]

Pfam domain/function: PF07848 PaaX; PF08223 PaaX_C [H]

EC number: NA

Molecular weight: Translated: 34165; Mature: 34033

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPGTDPVSPRVARLARGLKLGANSMLVTLFGDVVAPRPQAIWLGSLIRLAAPFGINDR
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
LVRTATFRLTADDWLAATRMGRRSYYGLSDAGLQRVLHAGKRIYAGEASEWDGRWTLVMV
EEEEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCCCEEEEEE
RGDVRATVRQKLKRELLWEGFGAIAPGVMAHPQADLASLREILQAARAQDDVAVMEASSL
ECCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCC
EAFSIRPLQALMHQTFKLGDVAAAWQALLRRFAPLAEEAAGLAPADAFFVRTLLVHEYRR
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLLRDPNLPEAMLPQDWPGRTARGLCHTLYGALLDASEDYLHRVVEAADGSLHDANRSLR
HHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
LRFGAGAQAGND
EEECCCCCCCCC
>Mature Secondary Structure 
ATPGTDPVSPRVARLARGLKLGANSMLVTLFGDVVAPRPQAIWLGSLIRLAAPFGINDR
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
LVRTATFRLTADDWLAATRMGRRSYYGLSDAGLQRVLHAGKRIYAGEASEWDGRWTLVMV
EEEEEEEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCCCEEEEEE
RGDVRATVRQKLKRELLWEGFGAIAPGVMAHPQADLASLREILQAARAQDDVAVMEASSL
ECCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCC
EAFSIRPLQALMHQTFKLGDVAAAWQALLRRFAPLAEEAAGLAPADAFFVRTLLVHEYRR
CHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VLLRDPNLPEAMLPQDWPGRTARGLCHTLYGALLDASEDYLHRVVEAADGSLHDANRSLR
HHHCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
LRFGAGAQAGND
EEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]