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The map label for this gene is actP [H]

Identifier: 116695281

GI number: 116695281

Start: 1482677

End: 1484248

Strand: Direct

Name: actP [H]

Synonym: H16_B1337

Alternate gene names: 116695281

Gene position: 1482677-1484248 (Clockwise)

Preceding gene: 116695280

Following gene: 116695284

Centisome position: 50.91

GC content: 64.57

Gene sequence:

>1572_bases
ATGAATCTCCAGGCCATTTCCATGTTCCTGCTCTTCGTCGCGCTGACGCTGGGCATCACGTACCGGGCCTCCTCGCGCAC
CCGGACCGCCAATGACTTCTTTACCGCAGGCGGCGGCATCACCGGCATGCAGAACGGCCTGGCCGTGGCGGGCGACTACA
TGTCGGCGGCCACGCTGCTCGGCGTGGTCAGCCTGGTCTATGCGCGCGGCTTTGACGGCCTGCTGTATATCGTCGGGTTC
TTCATCGGCTGGCCGGTCATGCTGTTCCTGATGGCCGAACGACTGCGTAATCTCGGCAAATTCACCTTCGTCGACATTAT
TTCGGACCGGCTCGATCCCGTCAGCACGCGCTGCATTGCAGCGGCCAGTAGCTTGGTGGTGGTGCTGCTCTACCTGATCG
TGCAAATGGTCGGCGCCGGCGAGTTGGTGCAGTTGTTGTTCGGCATCGACTATGTCTATGCCGTCATCGGGGTCGGCGTG
CTGATGATGATCTATGTGACTGTTGGCGGCATGATCGCGACGACATGGGTGCAGATCGTCAAGGCAGTGCTGCTGCTGTT
CGGCGGCTCGTTGCTGATGCTCCTGGCGCTGGGGCATTTCGGCTTCAGCCTTGAAGCGCTGGCTGCCAGGGCAATCGCGG
TGCACCGCAGCGGCCCCGCCCTGCTCGCGCCGGGCACGCTGTTCGCCGATCCGGTCTCGGCGCTCTCGCTGTGTGTGGCC
ACCGTGCTCGGGCTGTCGGGACTCCCGCATATCCTGATGCGCTTCTTTACGGTGCCGAATGCGTGCGAAGCACGCAAGAG
CGTGCTGGTAGCCAGCACCTGCATCGGTTACATGTTCCTCGCCATGTTTGCCATCGGACTTGCGGCCATCGTGATCGTCG
GTACCGATCCACGCTATTTTGAAGGCGGCCATGTCGGCGGAAAGCTGCTCGGCGGTGGCAACATGGTCGCGATGCACCTG
GCCAGCGCGACCGGCGGCAACCTGTTCCTCGGGTTCCTGGCGGCCGTCGCCTTTGCCACGATTCTCGCCGTGGTGTCGGG
CCTGACGCTGGCCGGTGCTTCGGCGATCTCGCACGACATCTACGCCGGTGTCCTACGGCGCGGCACTACCACCGAGGCAG
CCGAGATCGCCGTCACCAAAAAAGCCACGCTGGCCATCGGCATCGTTGCGGTGCTGCTGGGGATTGCCTTCAAAGGGCAG
AACCTGGCGTTCCTGGTCGCGCTGGCTTTCAATGTAGCGGCCTCGGCGAATTTCCCGGTGTTGGTGCTGTCGATGTACTG
GCGCGGCCTGACCAGCCGCGGCGCGGTCTGGGGCGTGGCGTCGGGCCTGGCGTCGTCGGTCGCGCTGGTGGTACTTTCCC
CTGCCGTCTGGAAGAACGTGCTGGGGCACCCCTCAGCCATCTTTCCGTACGACCACCCGGCGCTGTTCACAGTCCCGCTC
GCGTTCCTGGTCACATACCTGTGCTCGCGCTTCGACCGGAGCGCCAGGGCCGAGGCAGAGCGCCAGGCCTTCGACGCGCA
ACTGGTCCGCGCACAGACCGGCCATGGGGCGGCGGCACCATCCAGCCACTGA

Upstream 100 bases:

>100_bases
GAATCATGCTGCTGGGGTGGGGGGCGACGTGGTTCTACGTGCGCCGGGCCAACGGCGAGCTGGAAGCGATGGTGCAGCAG
ATCCTGTCGGAGGCCGGACA

Downstream 100 bases:

>100_bases
CCCCTGGCGCATGACCCGGCGCGGGTAGCGCGCCACACAGACGTGCAACCCGCTGCGGTAGCTCCGTGCTAGGTCGCTGC
AGGCGTCAGCGCGGCATAGA

Product: SSS family APC transporter

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MNLQAISMFLLFVALTLGITYRASSRTRTANDFFTAGGGITGMQNGLAVAGDYMSAATLLGVVSLVYARGFDGLLYIVGF
FIGWPVMLFLMAERLRNLGKFTFVDIISDRLDPVSTRCIAAASSLVVVLLYLIVQMVGAGELVQLLFGIDYVYAVIGVGV
LMMIYVTVGGMIATTWVQIVKAVLLLFGGSLLMLLALGHFGFSLEALAARAIAVHRSGPALLAPGTLFADPVSALSLCVA
TVLGLSGLPHILMRFFTVPNACEARKSVLVASTCIGYMFLAMFAIGLAAIVIVGTDPRYFEGGHVGGKLLGGGNMVAMHL
ASATGGNLFLGFLAAVAFATILAVVSGLTLAGASAISHDIYAGVLRRGTTTEAAEIAVTKKATLAIGIVAVLLGIAFKGQ
NLAFLVALAFNVAASANFPVLVLSMYWRGLTSRGAVWGVASGLASSVALVVLSPAVWKNVLGHPSAIFPYDHPALFTVPL
AFLVTYLCSRFDRSARAEAERQAFDAQLVRAQTGHGAAAPSSH

Sequences:

>Translated_523_residues
MNLQAISMFLLFVALTLGITYRASSRTRTANDFFTAGGGITGMQNGLAVAGDYMSAATLLGVVSLVYARGFDGLLYIVGF
FIGWPVMLFLMAERLRNLGKFTFVDIISDRLDPVSTRCIAAASSLVVVLLYLIVQMVGAGELVQLLFGIDYVYAVIGVGV
LMMIYVTVGGMIATTWVQIVKAVLLLFGGSLLMLLALGHFGFSLEALAARAIAVHRSGPALLAPGTLFADPVSALSLCVA
TVLGLSGLPHILMRFFTVPNACEARKSVLVASTCIGYMFLAMFAIGLAAIVIVGTDPRYFEGGHVGGKLLGGGNMVAMHL
ASATGGNLFLGFLAAVAFATILAVVSGLTLAGASAISHDIYAGVLRRGTTTEAAEIAVTKKATLAIGIVAVLLGIAFKGQ
NLAFLVALAFNVAASANFPVLVLSMYWRGLTSRGAVWGVASGLASSVALVVLSPAVWKNVLGHPSAIFPYDHPALFTVPL
AFLVTYLCSRFDRSARAEAERQAFDAQLVRAQTGHGAAAPSSH
>Mature_523_residues
MNLQAISMFLLFVALTLGITYRASSRTRTANDFFTAGGGITGMQNGLAVAGDYMSAATLLGVVSLVYARGFDGLLYIVGF
FIGWPVMLFLMAERLRNLGKFTFVDIISDRLDPVSTRCIAAASSLVVVLLYLIVQMVGAGELVQLLFGIDYVYAVIGVGV
LMMIYVTVGGMIATTWVQIVKAVLLLFGGSLLMLLALGHFGFSLEALAARAIAVHRSGPALLAPGTLFADPVSALSLCVA
TVLGLSGLPHILMRFFTVPNACEARKSVLVASTCIGYMFLAMFAIGLAAIVIVGTDPRYFEGGHVGGKLLGGGNMVAMHL
ASATGGNLFLGFLAAVAFATILAVVSGLTLAGASAISHDIYAGVLRRGTTTEAAEIAVTKKATLAIGIVAVLLGIAFKGQ
NLAFLVALAFNVAASANFPVLVLSMYWRGLTSRGAVWGVASGLASSVALVVLSPAVWKNVLGHPSAIFPYDHPALFTVPL
AFLVTYLCSRFDRSARAEAERQAFDAQLVRAQTGHGAAAPSSH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=475, Percent_Identity=24.4210526315789, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790503, Length=522, Percent_Identity=56.3218390804598, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1787251, Length=456, Percent_Identity=24.1228070175439, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54627; Mature: 54627

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQAISMFLLFVALTLGITYRASSRTRTANDFFTAGGGITGMQNGLAVAGDYMSAATLL
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHEECCCCCCCCCCCCEEHHHHHHHHHHH
GVVSLVYARGFDGLLYIVGFFIGWPVMLFLMAERLRNLGKFTFVDIISDRLDPVSTRCIA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
AASSLVVVLLYLIVQMVGAGELVQLLFGIDYVYAVIGVGVLMMIYVTVGGMIATTWVQIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLLFGGSLLMLLALGHFGFSLEALAARAIAVHRSGPALLAPGTLFADPVSALSLCVA
HHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHH
TVLGLSGLPHILMRFFTVPNACEARKSVLVASTCIGYMFLAMFAIGLAAIVIVGTDPRYF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEE
EGGHVGGKLLGGGNMVAMHLASATGGNLFLGFLAAVAFATILAVVSGLTLAGASAISHDI
CCCCCCCEEECCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YAGVLRRGTTTEAAEIAVTKKATLAIGIVAVLLGIAFKGQNLAFLVALAFNVAASANFPV
HHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
LVLSMYWRGLTSRGAVWGVASGLASSVALVVLSPAVWKNVLGHPSAIFPYDHPALFTVPL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCHHHHHHH
AFLVTYLCSRFDRSARAEAERQAFDAQLVRAQTGHGAAAPSSH
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNLQAISMFLLFVALTLGITYRASSRTRTANDFFTAGGGITGMQNGLAVAGDYMSAATLL
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHEECCCCCCCCCCCCEEHHHHHHHHHHH
GVVSLVYARGFDGLLYIVGFFIGWPVMLFLMAERLRNLGKFTFVDIISDRLDPVSTRCIA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
AASSLVVVLLYLIVQMVGAGELVQLLFGIDYVYAVIGVGVLMMIYVTVGGMIATTWVQIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLLFGGSLLMLLALGHFGFSLEALAARAIAVHRSGPALLAPGTLFADPVSALSLCVA
HHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHH
TVLGLSGLPHILMRFFTVPNACEARKSVLVASTCIGYMFLAMFAIGLAAIVIVGTDPRYF
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEE
EGGHVGGKLLGGGNMVAMHLASATGGNLFLGFLAAVAFATILAVVSGLTLAGASAISHDI
CCCCCCCEEECCCCEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YAGVLRRGTTTEAAEIAVTKKATLAIGIVAVLLGIAFKGQNLAFLVALAFNVAASANFPV
HHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCH
LVLSMYWRGLTSRGAVWGVASGLASSVALVVLSPAVWKNVLGHPSAIFPYDHPALFTVPL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCHHHHHHH
AFLVTYLCSRFDRSARAEAERQAFDAQLVRAQTGHGAAAPSSH
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA