Click here to switch to the map view.

The map label for this gene is gbpR [H]

Identifier: 116695164

GI number: 116695164

Start: 1378212

End: 1379201

Strand: Direct

Name: gbpR [H]

Synonym: H16_B1220

Alternate gene names: 116695164

Gene position: 1378212-1379201 (Clockwise)

Preceding gene: 116695163

Following gene: 116695165

Centisome position: 47.32

GC content: 68.48

Gene sequence:

>990_bases
ATGCCAGACCTCCCAGCCACCCTCTCCAGTGCCGCCACCCTGCGCAAACGCTTGCATATGCGGCATCTGCGCCTGGCCCT
GGCCCTTGCCGAGCACCGCTCGCTGCGGCGCGCCGCGGCACAGATGGCGCTGTCCCAGCCAGCCGTCACCAAGGCATTGC
ACGAGCTCGAGAGCGTGGTCGGCACGTTGCTGTTCACGCGGCATGCGCGCGGCATCGAGCCGACGGTGTTCGGCGAGGCG
CTGATCCGCTATGCGCGCGTGGTGCTGGCCGACCTGGATGCCCTGCACGATGAATTTGCCGCCATCGCCGCGGGCGAGGT
GGGCAAGGTGCGGCTCGGCTCGATCCTGGCCCCGGTGCCTTCCGTTCTGTCGGGCGTCATCAACGCGCTCAAGGCACGCT
ATCCGCGTTTGCATATCGTGATGCAGGTCGATACCAGCGACGTACTGGTACAGGCGCTGCGGCAGGATGCGCTGGACGTG
GTGATCGGACGCATTCCCGAAGGCACGGTGGCCGACGATCTCGACTTCGAGCCACTGTTCGAAGAGTCGCTGGCCATCGT
GGCGCGCGCCGGCCATCCGCAGGCAGGCAAGCGCGGCGTCAAGCTGGCTTCCCTGGCCGGCTATCCCTGGATCATCCCGC
CAGCGGCGGTGCCGATGTGGCAGATCATCGACCAGACCTTCCGCGACAACCGCGTGCCGCTGCCGGAAGACATCATCGAG
ACTTCGTCGATCATGGGCACGCTGCCGCTGCTGGCGGATAGCGACCGCATTGCCGTCGTGCCGGGCGCGATCGCGGAGTA
CTTCGTCGCCCTGGGTGCGCTGGCGGTCCTGCCGGTGGCGATGCGCGGGCGGCTGGTCCCCTATGGGATTGTGCTGCGCC
GGCGGCGGGCCGCGACGCCGGCCATGCGCCTGCTGATCGACGCGGTGCGCGCGGCGGGGCCCGGCGCTCCGCAGGCGATG
ACTGAATTGGAGCCATTACCTGCAAGGTAA

Upstream 100 bases:

>100_bases
GTTCTATCGGATCAATGTTCCAAGGCCGTCCGAGCTGGCCTAGAACCAGCGGCAGGCACAAGCATGCTATAAGTCCTATC
TTCGCCGCAGCCCGGCCACC

Downstream 100 bases:

>100_bases
TGGTCATACGCCGCGGTGCATGCTGTAATGCATGCCATGGACACGCTGACCCCAGCCTCCGAGGCCACCCTCGACTTCCC
CGGCCTGCTGCGCTACTGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPDLPATLSSAATLRKRLHMRHLRLALALAEHRSLRRAAAQMALSQPAVTKALHELESVVGTLLFTRHARGIEPTVFGEA
LIRYARVVLADLDALHDEFAAIAAGEVGKVRLGSILAPVPSVLSGVINALKARYPRLHIVMQVDTSDVLVQALRQDALDV
VIGRIPEGTVADDLDFEPLFEESLAIVARAGHPQAGKRGVKLASLAGYPWIIPPAAVPMWQIIDQTFRDNRVPLPEDIIE
TSSIMGTLPLLADSDRIAVVPGAIAEYFVALGALAVLPVAMRGRLVPYGIVLRRRRAATPAMRLLIDAVRAAGPGAPQAM
TELEPLPAR

Sequences:

>Translated_329_residues
MPDLPATLSSAATLRKRLHMRHLRLALALAEHRSLRRAAAQMALSQPAVTKALHELESVVGTLLFTRHARGIEPTVFGEA
LIRYARVVLADLDALHDEFAAIAAGEVGKVRLGSILAPVPSVLSGVINALKARYPRLHIVMQVDTSDVLVQALRQDALDV
VIGRIPEGTVADDLDFEPLFEESLAIVARAGHPQAGKRGVKLASLAGYPWIIPPAAVPMWQIIDQTFRDNRVPLPEDIIE
TSSIMGTLPLLADSDRIAVVPGAIAEYFVALGALAVLPVAMRGRLVPYGIVLRRRRAATPAMRLLIDAVRAAGPGAPQAM
TELEPLPAR
>Mature_328_residues
PDLPATLSSAATLRKRLHMRHLRLALALAEHRSLRRAAAQMALSQPAVTKALHELESVVGTLLFTRHARGIEPTVFGEAL
IRYARVVLADLDALHDEFAAIAAGEVGKVRLGSILAPVPSVLSGVINALKARYPRLHIVMQVDTSDVLVQALRQDALDVV
IGRIPEGTVADDLDFEPLFEESLAIVARAGHPQAGKRGVKLASLAGYPWIIPPAAVPMWQIIDQTFRDNRVPLPEDIIET
SSIMGTLPLLADSDRIAVVPGAIAEYFVALGALAVLPVAMRGRLVPYGIVLRRRRAATPAMRLLIDAVRAAGPGAPQAMT
ELEPLPAR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=307, Percent_Identity=26.7100977198697, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=24.8299319727891, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789506, Length=265, Percent_Identity=24.9056603773585, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=31.5589353612167, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790399, Length=191, Percent_Identity=29.8429319371728, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=23.2876712328767, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=228, Percent_Identity=25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI145693105, Length=290, Percent_Identity=25.5172413793103, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788887, Length=302, Percent_Identity=24.1721854304636, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=24.406779661017, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35388; Mature: 35257

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLPATLSSAATLRKRLHMRHLRLALALAEHRSLRRAAAQMALSQPAVTKALHELESVV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GTLLFTRHARGIEPTVFGEALIRYARVVLADLDALHDEFAAIAAGEVGKVRLGSILAPVP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SVLSGVINALKARYPRLHIVMQVDTSDVLVQALRQDALDVVIGRIPEGTVADDLDFEPLF
HHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
EESLAIVARAGHPQAGKRGVKLASLAGYPWIIPPAAVPMWQIIDQTFRDNRVPLPEDIIE
HHHHHHHHCCCCCCCCCCCCEEHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
TSSIMGTLPLLADSDRIAVVPGAIAEYFVALGALAVLPVAMRGRLVPYGIVLRRRRAATP
HHHHHHHHCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
AMRLLIDAVRAAGPGAPQAMTELEPLPAR
HHHHHHHHHHHCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
PDLPATLSSAATLRKRLHMRHLRLALALAEHRSLRRAAAQMALSQPAVTKALHELESVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GTLLFTRHARGIEPTVFGEALIRYARVVLADLDALHDEFAAIAAGEVGKVRLGSILAPVP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SVLSGVINALKARYPRLHIVMQVDTSDVLVQALRQDALDVVIGRIPEGTVADDLDFEPLF
HHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
EESLAIVARAGHPQAGKRGVKLASLAGYPWIIPPAAVPMWQIIDQTFRDNRVPLPEDIIE
HHHHHHHHCCCCCCCCCCCCEEHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHH
TSSIMGTLPLLADSDRIAVVPGAIAEYFVALGALAVLPVAMRGRLVPYGIVLRRRRAATP
HHHHHHHHCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
AMRLLIDAVRAAGPGAPQAMTELEPLPAR
HHHHHHHHHHHCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]