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The map label for this gene is ttuB [H]

Identifier: 116695162

GI number: 116695162

Start: 1375870

End: 1377207

Strand: Direct

Name: ttuB [H]

Synonym: H16_B1218

Alternate gene names: 116695162

Gene position: 1375870-1377207 (Clockwise)

Preceding gene: 116695161

Following gene: 116695163

Centisome position: 47.24

GC content: 68.54

Gene sequence:

>1338_bases
ATGAAAGGCTTGGACCAAGCCGGCGCCGGCACGTCGGTCGCCATCGATGCGACACCACTCACCGGTGCCGCCAGCATTCC
AGCCCAGCGCTGGTGGCGCATCATCCCGCCGATCCTGATGGTCTGCATCGTCTCGTACATGGATCGCGTCAATATCGCCT
TCGCGATGCCGGGGGGGATGGGCGATGCGCTCGGTATCGGCGCCAGCATGGCCGGCCTGGCCGGCGGCATCTTCTTTGTC
GGCTATCTGTTCCTGCAGATTCCCGGCGGCAAGCTGGCCGTGCGCGGCAGCGGGCGCAATTTCATCGCCTGGTCGATGCT
GGCCTGGGCCGTCATTTCCGTGCTGACCGGCCTGGTGCGCAACGAGACCGAACTGCTGATTCTGCGCTTTGCGCTGGGGG
TGGCCGAGGGCGGCATGCTGCCGGTGGTGCTGACCATGGTCGGCAACTGGTTTCCCGACCACGAACGCGGACGCGCCAAC
GCCCTGGTGATCCTGTTCGTGCCGATCGCCGGCGTCATCACCGCGCCGCTGTCGGGCCTGGTAATCGCGGCGCTCGACTG
GCGCTGGCTGTTTATCGTGGAAGGCCTGATTTCGCTGGCCTGCCTCGGCGTGTGGTGGAAGCTGGCCTGTGACCGGCCGG
AGCAGGCGCGCTGGATTTCCGCCGAAGAGAAGGCTTATCTGCTGGCCCGCCTGCGCGAGGAAGAGCAGCAGGCAGCCGCC
GCTGGCGCAAGCGTGGGGCAGGGCGCGGCCGACACGCGGGCGGTATTGGCGCACATCCTGTCGCAGGACGTGATCTGGCG
CCTGATCGCCGTCAATTTTCTCTACCAGATGGGGATCTACGGGTACACGCTGTGGCTGCCCACCATCCTGAGGGGCCTGA
CCGGAGGCGGCATGGGGCAGGTCGGCATGCTGGCCGTGCTGCCGTACCTGGGCACCATGGCCGGCATCCTCGCGATCTCC
TCGCTGTCCGACCGCACCGGCCGGCGCAAGGACTTCGTGGTCTGGCCGCTGCTGGGTTTCGCCGCCTGCCTGGCCGGTTC
GGTCTGGTGGCACGACAATACCTGGCTGTCCTATGGCCTGCTGGTCGGCAGCGGCTTCTTCCTGCAGTCCGCGGCGGGGG
TCTTCTGGACCCTGCCGCCACGGCTGCTGGCCGCCGAGCACGCGGGCGTGGCGCGCGGCGTGATTAATGCGCTGGGCAAC
CTGGGCGGATTCTGCGGTCCCTATGCCGCGGGCGTGCTGATCGAGCGCGTCAGCGCGGGCGCCGGTGTCTACCTGCTGGT
CGCCGCGCTGGTGATGGCCGGCGCCCTGGCCGCCACGCTGCCGAGGCGGTGCCGATGA

Upstream 100 bases:

>100_bases
ATCCTGGCTTTGCCGACGCGGTAGTCAACCGGCGTTCACGGCCGCGAAGGCAGCGCGGATGCCAGCGGCCCATACCCGGA
AATCCATACGGAGACAGAGT

Downstream 100 bases:

>100_bases
GCAGCGTAACAACTGCCGCGCTGCCCGCAGGCCTGGCCATCGTCGACGCCCACCACCACCTGTGGCAACTCGGGCGCGGC
CGCTATCCCTGGCTGCAGGA

Product: MFS transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKGLDQAGAGTSVAIDATPLTGAASIPAQRWWRIIPPILMVCIVSYMDRVNIAFAMPGGMGDALGIGASMAGLAGGIFFV
GYLFLQIPGGKLAVRGSGRNFIAWSMLAWAVISVLTGLVRNETELLILRFALGVAEGGMLPVVLTMVGNWFPDHERGRAN
ALVILFVPIAGVITAPLSGLVIAALDWRWLFIVEGLISLACLGVWWKLACDRPEQARWISAEEKAYLLARLREEEQQAAA
AGASVGQGAADTRAVLAHILSQDVIWRLIAVNFLYQMGIYGYTLWLPTILRGLTGGGMGQVGMLAVLPYLGTMAGILAIS
SLSDRTGRRKDFVVWPLLGFAACLAGSVWWHDNTWLSYGLLVGSGFFLQSAAGVFWTLPPRLLAAEHAGVARGVINALGN
LGGFCGPYAAGVLIERVSAGAGVYLLVAALVMAGALAATLPRRCR

Sequences:

>Translated_445_residues
MKGLDQAGAGTSVAIDATPLTGAASIPAQRWWRIIPPILMVCIVSYMDRVNIAFAMPGGMGDALGIGASMAGLAGGIFFV
GYLFLQIPGGKLAVRGSGRNFIAWSMLAWAVISVLTGLVRNETELLILRFALGVAEGGMLPVVLTMVGNWFPDHERGRAN
ALVILFVPIAGVITAPLSGLVIAALDWRWLFIVEGLISLACLGVWWKLACDRPEQARWISAEEKAYLLARLREEEQQAAA
AGASVGQGAADTRAVLAHILSQDVIWRLIAVNFLYQMGIYGYTLWLPTILRGLTGGGMGQVGMLAVLPYLGTMAGILAIS
SLSDRTGRRKDFVVWPLLGFAACLAGSVWWHDNTWLSYGLLVGSGFFLQSAAGVFWTLPPRLLAAEHAGVARGVINALGN
LGGFCGPYAAGVLIERVSAGAGVYLLVAALVMAGALAATLPRRCR
>Mature_445_residues
MKGLDQAGAGTSVAIDATPLTGAASIPAQRWWRIIPPILMVCIVSYMDRVNIAFAMPGGMGDALGIGASMAGLAGGIFFV
GYLFLQIPGGKLAVRGSGRNFIAWSMLAWAVISVLTGLVRNETELLILRFALGVAEGGMLPVVLTMVGNWFPDHERGRAN
ALVILFVPIAGVITAPLSGLVIAALDWRWLFIVEGLISLACLGVWWKLACDRPEQARWISAEEKAYLLARLREEEQQAAA
AGASVGQGAADTRAVLAHILSQDVIWRLIAVNFLYQMGIYGYTLWLPTILRGLTGGGMGQVGMLAVLPYLGTMAGILAIS
SLSDRTGRRKDFVVWPLLGFAACLAGSVWWHDNTWLSYGLLVGSGFFLQSAAGVFWTLPPRLLAAEHAGVARGVINALGN
LGGFCGPYAAGVLIERVSAGAGVYLLVAALVMAGALAATLPRRCR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=381, Percent_Identity=25.7217847769029, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI9966811, Length=381, Percent_Identity=23.6220472440945, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4885441, Length=325, Percent_Identity=25.2307692307692, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9945322, Length=381, Percent_Identity=21.7847769028871, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082071, Length=384, Percent_Identity=29.1666666666667, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87082320, Length=438, Percent_Identity=25.5707762557078, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=25.6470588235294, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789152, Length=421, Percent_Identity=24.9406175771971, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI2367379, Length=292, Percent_Identity=22.9452054794521, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367193, Length=283, Percent_Identity=25.0883392226148, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=326, Percent_Identity=27.9141104294479, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533556, Length=389, Percent_Identity=23.3933161953728, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=389, Percent_Identity=23.3933161953728, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193205400, Length=240, Percent_Identity=21.6666666666667, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=327, Percent_Identity=22.3241590214067, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641682, Length=394, Percent_Identity=27.1573604060914, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24584153, Length=363, Percent_Identity=23.6914600550964, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI20130167, Length=404, Percent_Identity=23.019801980198, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583789, Length=394, Percent_Identity=22.8426395939086, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24648416, Length=467, Percent_Identity=22.6980728051392, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356189, Length=467, Percent_Identity=22.6980728051392, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573708, Length=236, Percent_Identity=24.1525423728814, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573707, Length=236, Percent_Identity=24.1525423728814, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24658658, Length=353, Percent_Identity=23.2294617563739, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24655255, Length=409, Percent_Identity=22.2493887530562, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550460, Length=310, Percent_Identity=23.5483870967742, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639764, Length=356, Percent_Identity=24.438202247191, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658666, Length=369, Percent_Identity=23.0352303523035, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221474708, Length=218, Percent_Identity=27.9816513761468, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922400, Length=370, Percent_Identity=24.8648648648649, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24654215, Length=370, Percent_Identity=24.8648648648649, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI20130135, Length=300, Percent_Identity=22, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24655271, Length=307, Percent_Identity=22.4755700325733, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24653727, Length=423, Percent_Identity=23.6406619385343, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129235, Length=353, Percent_Identity=24.3626062322946, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580790, Length=254, Percent_Identity=22.8346456692913, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47133; Mature: 47133

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLDQAGAGTSVAIDATPLTGAASIPAQRWWRIIPPILMVCIVSYMDRVNIAFAMPGGM
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GDALGIGASMAGLAGGIFFVGYLFLQIPGGKLAVRGSGRNFIAWSMLAWAVISVLTGLVR
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
NETELLILRFALGVAEGGMLPVVLTMVGNWFPDHERGRANALVILFVPIAGVITAPLSGL
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHH
VIAALDWRWLFIVEGLISLACLGVWWKLACDRPEQARWISAEEKAYLLARLREEEQQAAA
EEHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
AGASVGQGAADTRAVLAHILSQDVIWRLIAVNFLYQMGIYGYTLWLPTILRGLTGGGMGQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VGMLAVLPYLGTMAGILAISSLSDRTGRRKDFVVWPLLGFAACLAGSVWWHDNTWLSYGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEECCCCHHHHHH
LVGSGFFLQSAAGVFWTLPPRLLAAEHAGVARGVINALGNLGGFCGPYAAGVLIERVSAG
HHCCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
AGVYLLVAALVMAGALAATLPRRCR
CCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKGLDQAGAGTSVAIDATPLTGAASIPAQRWWRIIPPILMVCIVSYMDRVNIAFAMPGGM
CCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GDALGIGASMAGLAGGIFFVGYLFLQIPGGKLAVRGSGRNFIAWSMLAWAVISVLTGLVR
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHC
NETELLILRFALGVAEGGMLPVVLTMVGNWFPDHERGRANALVILFVPIAGVITAPLSGL
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHCHHHH
VIAALDWRWLFIVEGLISLACLGVWWKLACDRPEQARWISAEEKAYLLARLREEEQQAAA
EEHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHH
AGASVGQGAADTRAVLAHILSQDVIWRLIAVNFLYQMGIYGYTLWLPTILRGLTGGGMGQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VGMLAVLPYLGTMAGILAISSLSDRTGRRKDFVVWPLLGFAACLAGSVWWHDNTWLSYGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCEECCCCHHHHHH
LVGSGFFLQSAAGVFWTLPPRLLAAEHAGVARGVINALGNLGGFCGPYAAGVLIERVSAG
HHCCCHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
AGVYLLVAALVMAGALAATLPRRCR
CCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]