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The map label for this gene is namA [H]

Identifier: 116695087

GI number: 116695087

Start: 1296361

End: 1297476

Strand: Direct

Name: namA [H]

Synonym: H16_B1142

Alternate gene names: 116695087

Gene position: 1296361-1297476 (Clockwise)

Preceding gene: 116695086

Following gene: 116695088

Centisome position: 44.51

GC content: 68.1

Gene sequence:

>1116_bases
ATGAGCTTTCTGTTCGAACCGCTCGCCATCGGCGATCTCACCCTCGCCAACCGCATCATCATCGCCCCGATGTGCCAGTA
CTCCGCGCGGGACGGCAACGCCGGCGACTGGCACATGATCCACCTCGGTTCGCTGGCGCTGTCCGGCGCCGGCATGCTGA
TCGTGGAAGCCACGGCAGTCTCGCCCGAAGGGCGCATCACGCCGCAGGACCTGGGCCTGTATTCGGACGAAAACGAGGCG
GCGCTTGGCCGCGTGGTCAAGGCGATGCGCGCGCATTCGCCGATCGCCATTGCGATCCAGTTGGGGCATGCCGGCCGCAA
GGCGTCGAGCCAGGCGCCATGGGATGGCGGGCAGCAGATCGCGCCGGATGCGCCTGGTGGCTGGCATGCGGTGGCGCCTT
CCGCGGTACCGCATGGCGCGGAAGAAGTCGCGCCTGCCGCGCTGGACCGTGCCGGCATGGACAAGGTGCGCGACGACTTT
GTCGCGGCGGCAAGGCGTGCGGCGCGGCTTGGGTTGAACGGGATCGAGATCCATGCCGCGCACGGCTACCTGCTGCACCA
GTTCCTGTCGCCGCTGGCCAACCATCGTGACGACGAATACGGCGGCAGCCTGGAGAACCGCATGCGGTTCCCGATCGAGG
TGTTCGACGCGGTGCGTGAGGTGTTCCCGGCTGAGCGTCCGGTGTGGATGCGTATTTCCGCAACCGACTGGGTGCCGGGC
GGATGGGATATCGAAGGCACGGTGGCGTTGTCGAAGGCTCTCAAGGCGCGCGGCTGTGCGGCGATCCATGTGACCACCGG
CGGCGTGTCGCCGCAGCAGGCGATCAAGCTCGGGCCCGGCTACCAGGTGCCGTACGCGCAGCGCGTAAAGGCCGAGGTTG
GCCTGCCGACGATTGCGGTGGGCCTGATCACTGAGCCGGAGCAGGCCGAAGCCATCATCGCCAACCACGAAGCCGACGCG
GTGTCGCTGGCCCGTGCCATGCTGTATGACCCGCGCTGGCCCTGGCATGCGGCCGCGCGGCTGGGCGCAAGCGTGCAGGC
GCCGAAGCAATACTGGCGGTCGCAGCCGCGCGAACTGAAAGACCTGTTTGCCGATGCGGCTTTCGGGCAGCGCTAG

Upstream 100 bases:

>100_bases
TCCGTTGGCGGCGTCGTAGCGGCGCGGCCGGGCCGGCAGCAATTCCGGCGCCGGCCTAGAATCGATATTTCCTGTCCGAT
CCCTGCATGGAGCAGCACGC

Downstream 100 bases:

>100_bases
GCTGCCGGTCGATACAGGAGGAACCCGCCATGAGACCCCGGATTACGCTGATCACGCTGGGTGTCGATGACCTGCAGCGT
GCGGTGCGCTTCTATCGCGA

Product: NADH:flavin oxidoreductase/NADH oxidase family protein

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSFLFEPLAIGDLTLANRIIIAPMCQYSARDGNAGDWHMIHLGSLALSGAGMLIVEATAVSPEGRITPQDLGLYSDENEA
ALGRVVKAMRAHSPIAIAIQLGHAGRKASSQAPWDGGQQIAPDAPGGWHAVAPSAVPHGAEEVAPAALDRAGMDKVRDDF
VAAARRAARLGLNGIEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVREVFPAERPVWMRISATDWVPG
GWDIEGTVALSKALKARGCAAIHVTTGGVSPQQAIKLGPGYQVPYAQRVKAEVGLPTIAVGLITEPEQAEAIIANHEADA
VSLARAMLYDPRWPWHAAARLGASVQAPKQYWRSQPRELKDLFADAAFGQR

Sequences:

>Translated_371_residues
MSFLFEPLAIGDLTLANRIIIAPMCQYSARDGNAGDWHMIHLGSLALSGAGMLIVEATAVSPEGRITPQDLGLYSDENEA
ALGRVVKAMRAHSPIAIAIQLGHAGRKASSQAPWDGGQQIAPDAPGGWHAVAPSAVPHGAEEVAPAALDRAGMDKVRDDF
VAAARRAARLGLNGIEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVREVFPAERPVWMRISATDWVPG
GWDIEGTVALSKALKARGCAAIHVTTGGVSPQQAIKLGPGYQVPYAQRVKAEVGLPTIAVGLITEPEQAEAIIANHEADA
VSLARAMLYDPRWPWHAAARLGASVQAPKQYWRSQPRELKDLFADAAFGQR
>Mature_370_residues
SFLFEPLAIGDLTLANRIIIAPMCQYSARDGNAGDWHMIHLGSLALSGAGMLIVEATAVSPEGRITPQDLGLYSDENEAA
LGRVVKAMRAHSPIAIAIQLGHAGRKASSQAPWDGGQQIAPDAPGGWHAVAPSAVPHGAEEVAPAALDRAGMDKVRDDFV
AAARRAARLGLNGIEIHAAHGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVREVFPAERPVWMRISATDWVPGG
WDIEGTVALSKALKARGCAAIHVTTGGVSPQQAIKLGPGYQVPYAQRVKAEVGLPTIAVGLITEPEQAEAIIANHEADAV
SLARAMLYDPRWPWHAAARLGASVQAPKQYWRSQPRELKDLFADAAFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=350, Percent_Identity=32.8571428571429, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1789463, Length=340, Percent_Identity=28.2352941176471, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI72001454, Length=274, Percent_Identity=27.7372262773723, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=261, Percent_Identity=28.735632183908, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=302, Percent_Identity=26.158940397351, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=172, Percent_Identity=33.1395348837209, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=282, Percent_Identity=25.177304964539, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=231, Percent_Identity=29.4372294372294, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565138, Length=260, Percent_Identity=25, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=244, Percent_Identity=33.6065573770492, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=244, Percent_Identity=31.5573770491803, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39773; Mature: 39641

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLFEPLAIGDLTLANRIIIAPMCQYSARDGNAGDWHMIHLGSLALSGAGMLIVEATAV
CCCCCCCHHHCCHHHHCEEEEEEHHHCCCCCCCCCCEEEEEECCCHHCCCCEEEEEEEEE
SPEGRITPQDLGLYSDENEAALGRVVKAMRAHSPIAIAIQLGHAGRKASSQAPWDGGQQI
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
APDAPGGWHAVAPSAVPHGAEEVAPAALDRAGMDKVRDDFVAAARRAARLGLNGIEIHAA
CCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
HGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVREVFPAERPVWMRISATDWVPG
CHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTVALSKALKARGCAAIHVTTGGVSPQQAIKLGPGYQVPYAQRVKAEVGLPTIAV
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHEECCCCCCCCHHHHHHHHCCCCEEEE
GLITEPEQAEAIIANHEADAVSLARAMLYDPRWPWHAAARLGASVQAPKQYWRSQPRELK
EEECCCHHHCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHCCCHHHH
DLFADAAFGQR
HHHHHHHCCCC
>Mature Secondary Structure 
SFLFEPLAIGDLTLANRIIIAPMCQYSARDGNAGDWHMIHLGSLALSGAGMLIVEATAV
CCCCCCHHHCCHHHHCEEEEEEHHHCCCCCCCCCCEEEEEECCCHHCCCCEEEEEEEEE
SPEGRITPQDLGLYSDENEAALGRVVKAMRAHSPIAIAIQLGHAGRKASSQAPWDGGQQI
CCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
APDAPGGWHAVAPSAVPHGAEEVAPAALDRAGMDKVRDDFVAAARRAARLGLNGIEIHAA
CCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
HGYLLHQFLSPLANHRDDEYGGSLENRMRFPIEVFDAVREVFPAERPVWMRISATDWVPG
CHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCC
GWDIEGTVALSKALKARGCAAIHVTTGGVSPQQAIKLGPGYQVPYAQRVKAEVGLPTIAV
CCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHEECCCCCCCCHHHHHHHHCCCCEEEE
GLITEPEQAEAIIANHEADAVSLARAMLYDPRWPWHAAARLGASVQAPKQYWRSQPRELK
EEECCCHHHCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHCCCHHHH
DLFADAAFGQR
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA