BacMap

Definition	Ralstonia eutropha H16 chromosome 2, complete sequence.
Accession	NC_008314
Length	2,912,490

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The map label for this gene is fabG [H]

Identifier: 116695020

GI number: 116695020

Start: 1214957

End: 1215727

Strand: Direct

Name: fabG [H]

Synonym: H16_B1075

Alternate gene names: 116695020

Gene position: 1214957-1215727 (Clockwise)

Preceding gene: 116695019

Following gene: 116695021

Centisome position: 41.72

GC content: 63.68

Gene sequence:

>771_bases
GTGGGCGCTACCGCTTCTGCGCAGCCATGGCGCGCTGGGGATGCCGTGTCAAATTTCTATGATCTTTCGGGGAAGGCAGC
GCTGGTGACCGGCGGTGCAAAGGGGCTCGGCCGGGCGATCGTTGCGCAACTGATCGACAGTGGTGCGCGTGTGCATGCTT
GGGATATCGTGCCGTTCCAGATGGAAGGTGCCAGCACTGAGGTCGTCGATGTCTCCGATGCCGGGCAGGTGGGGCTGGCG
CTGGCGCGACTGGTCGATGCGGGATATCGCTTCGACATCCTGGTCAACGCTGCCGGCTACCTTGGCCCGATGCAGCCATT
CGAGAATCACGAGGCTTCACAATGGCATCGCATCATCGCCGTGAATCTCCTGGGGACCATGTACGTCGTGCAGGCGATGT
TGCCGCACATGTTGCGCTGGGGAGGCGGCCGTATCATCAATATGGGCTCGCTGGCCGGCAAGGAGGGGCTGGCCGGGCTG
GCTGCATACTCCGCGGCCAGCGGCGGCGTGGTCGTTCTAACCAAAGCAATCGGCCGCGAACTGGTGAAGCGCAACATCTA
CGTTAATTGCGTGGCGCCCGGGCCCATGGATACCGACATGATTCACGGGCTCGGCAGCCACGAGGTGGCGGCCATGGTTG
CTGATAGCCCGGCCGGGCGCCTGGGCGATCCGGCCGAGGCTGCGCACCTGGTAGCGTGGCTATGTTCGGACGCCAGCCGC
TTTAATGCAGGCGCTGTCTTTGACATGTCCGGTGGGCGGGCGCGATTTTAA

Upstream 100 bases:

>100_bases
GGATCGGCGGGTGGGCTGCATGGCAAGCCCTGTCGCCGATGACGCGACGAGGCAAGGCTCAGGGCAGTTGCCTGCGTCAT
AAGGCGGGGCGGCGTGTGCC

Downstream 100 bases:

>100_bases
GGAAGTGCGGATCTTCGGTTGGCATGCCGTGAGATCGATTCGATAATCCGCTCCGACCCGGGCGTCTACGGCTTGATCTT
CCGCGAATCGCAGCACGCGA

Product: 3-oxoacyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGATASAQPWRAGDAVSNFYDLSGKAALVTGGAKGLGRAIVAQLIDSGARVHAWDIVPFQMEGASTEVVDVSDAGQVGLA
LARLVDAGYRFDILVNAAGYLGPMQPFENHEASQWHRIIAVNLLGTMYVVQAMLPHMLRWGGGRIINMGSLAGKEGLAGL
AAYSAASGGVVVLTKAIGRELVKRNIYVNCVAPGPMDTDMIHGLGSHEVAAMVADSPAGRLGDPAEAAHLVAWLCSDASR
FNAGAVFDMSGGRARF

Sequences:

>Translated_256_residues
MGATASAQPWRAGDAVSNFYDLSGKAALVTGGAKGLGRAIVAQLIDSGARVHAWDIVPFQMEGASTEVVDVSDAGQVGLA
LARLVDAGYRFDILVNAAGYLGPMQPFENHEASQWHRIIAVNLLGTMYVVQAMLPHMLRWGGGRIINMGSLAGKEGLAGL
AAYSAASGGVVVLTKAIGRELVKRNIYVNCVAPGPMDTDMIHGLGSHEVAAMVADSPAGRLGDPAEAAHLVAWLCSDASR
FNAGAVFDMSGGRARF
>Mature_255_residues
GATASAQPWRAGDAVSNFYDLSGKAALVTGGAKGLGRAIVAQLIDSGARVHAWDIVPFQMEGASTEVVDVSDAGQVGLAL
ARLVDAGYRFDILVNAAGYLGPMQPFENHEASQWHRIIAVNLLGTMYVVQAMLPHMLRWGGGRIINMGSLAGKEGLAGLA
AYSAASGGVVVLTKAIGRELVKRNIYVNCVAPGPMDTDMIHGLGSHEVAAMVADSPAGRLGDPAEAAHLVAWLCSDASRF
NAGAVFDMSGGRARF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=31.8181818181818, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=30.1158301158301, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=33.4677419354839, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=32.8, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI66933014, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI83715985, Length=250, Percent_Identity=30.8, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=31.219512195122, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=30.0518134715026, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=28.6307053941909, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4504505, Length=248, Percent_Identity=29.8387096774194, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503301, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=236, Percent_Identity=27.9661016949153, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=27.8225806451613, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=34.1666666666667, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=30.4, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786812, Length=232, Percent_Identity=32.7586206896552, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788459, Length=233, Percent_Identity=33.0472103004292, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.6205533596838, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.2040816326531, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=32.5301204819277, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=29.0322580645161, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=24.5967741935484, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=246, Percent_Identity=25.609756097561, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=175, Percent_Identity=29.7142857142857, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=34.156378600823, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=242, Percent_Identity=33.0578512396694, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=28.6852589641434, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=31.4393939393939, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.8897637795276, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=29, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=263, Percent_Identity=29.6577946768061, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=29, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=29.1457286432161, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=28, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=204, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=238, Percent_Identity=25.2100840336134, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=27.3092369477912, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.6, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=243, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=241, Percent_Identity=26.1410788381743, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=239, Percent_Identity=24.2677824267782, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323458, Length=187, Percent_Identity=30.4812834224599, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=28.8770053475936, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=33.8645418326693, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17737361, Length=226, Percent_Identity=34.5132743362832, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=31.5573770491803, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=232, Percent_Identity=27.1551724137931, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.1914893617021, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=27.7566539923954, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=25.7731958762887, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=24.7572815533981, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=243, Percent_Identity=28.8065843621399, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=28.9017341040462, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581726, Length=221, Percent_Identity=25.7918552036199, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26618; Mature: 26487

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATASAQPWRAGDAVSNFYDLSGKAALVTGGAKGLGRAIVAQLIDSGARVHAWDIVPFQ
CCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEE
MEGASTEVVDVSDAGQVGLALARLVDAGYRFDILVNAAGYLGPMQPFENHEASQWHRIIA
ECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
VNLLGTMYVVQAMLPHMLRWGGGRIINMGSLAGKEGLAGLAAYSAASGGVVVLTKAIGRE
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEHHHHHHH
LVKRNIYVNCVAPGPMDTDMIHGLGSHEVAAMVADSPAGRLGDPAEAAHLVAWLCSDASR
HHHCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
FNAGAVFDMSGGRARF
CCCCEEEECCCCCCCC
>Mature Secondary Structure 
GATASAQPWRAGDAVSNFYDLSGKAALVTGGAKGLGRAIVAQLIDSGARVHAWDIVPFQ
CCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEE
MEGASTEVVDVSDAGQVGLALARLVDAGYRFDILVNAAGYLGPMQPFENHEASQWHRIIA
ECCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHH
VNLLGTMYVVQAMLPHMLRWGGGRIINMGSLAGKEGLAGLAAYSAASGGVVVLTKAIGRE
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEHHHHHHH
LVKRNIYVNCVAPGPMDTDMIHGLGSHEVAAMVADSPAGRLGDPAEAAHLVAWLCSDASR
HHHCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
FNAGAVFDMSGGRARF
CCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]