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The map label for this gene is tauD [H]

Identifier: 116694949

GI number: 116694949

Start: 1129521

End: 1130363

Strand: Direct

Name: tauD [H]

Synonym: H16_B1004

Alternate gene names: 116694949

Gene position: 1129521-1130363 (Clockwise)

Preceding gene: 116694948

Following gene: 116694950

Centisome position: 38.78

GC content: 65.84

Gene sequence:

>843_bases
ATGCGAGCCCAACCGCTTACCTGCAATATCGGCGCCGAAGTCAGCGGCGTCAGCCTGGCCGATGCCGCGCGCGACGACGC
GCTGTTTGCCGAGATCAAGTCCCTGCTGCTCACGCACAAGGTGCTGTTCCTGCGCGACCAGGAAATCTCCCGCGCGGACC
ACGTGGCGTTCGCGCGCCGCTTCGGCGAACTGGAAGACCATCCCGTCGCCGGCAGCGATCCCGATCATCCAGGGCTGGTC
CAGATCTATCGCAGCGACAAGCGCGAGAACTACGAGAACAGCTACCACACCGATGGCAGCTGGCGCGAAACCCCGCCCAT
GGGCTGCGTGCTGCGCTGCATCGAATGCCCGCCGGTCGGCGGCGACACCATCTGGGTCAACATGGCGGCGGCCTACGAGC
ACCTGCCCGAGGAAATCAAGCAGCGCATCGCCGGCCTGCGCGCCAAGCACAGCATCGAGCATTCGTTCGGCGCGGCGATG
AGCCCGGAAAAGCGCGCCAGCCTTGCCGCGCAGTACCCCATGGTCGAGCACCCGGTGGTGCGCACGCATCCGGAAACCGG
CGAGAAGGCGCTCTACGTCTGCGGCTTCTCCACGCATTTCGCCAACTTCCATACGCCCGAGAACGTGCGCTACGGACAGG
ACAAGACCCCGGGCGCCAGCCATCTGCTGAACTACCTGATCAGCCAGGCGGCGATTCCCGAATACCAGGTGCGTTTCCGC
TGGCAGCCCAACAGTGTGGCCATCTGGGACAACCGCTGCACCCAGCACTACGCGGTGCAGGACTACTGGCCGGCGCCGCG
CAAGATGGAGCGCGCCGCCATCATCGGCGACAAGCCGTTCTGA

Upstream 100 bases:

>100_bases
CCAGCGCTATGCGCTGCAGGATGCCGTGCAGGCCCACCGCGACCTGGAATCACGCAAGACCACCGGGTCTTCGATCTTTG
TGCTGTAAAGGAGCGTCCCC

Downstream 100 bases:

>100_bases
GGCGCACCAGCCGCCGCCAGGCCACGTGCCTTTATCAATGGAGACATGCCGTGCACTACCTCGATGGATCCCTGTTCCCT
GAAAACCAGCAGCCGCTGAT

Product: Alpha-ketoglutarate-dependent taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRAQPLTCNIGAEVSGVSLADAARDDALFAEIKSLLLTHKVLFLRDQEISRADHVAFARRFGELEDHPVAGSDPDHPGLV
QIYRSDKRENYENSYHTDGSWRETPPMGCVLRCIECPPVGGDTIWVNMAAAYEHLPEEIKQRIAGLRAKHSIEHSFGAAM
SPEKRASLAAQYPMVEHPVVRTHPETGEKALYVCGFSTHFANFHTPENVRYGQDKTPGASHLLNYLISQAAIPEYQVRFR
WQPNSVAIWDNRCTQHYAVQDYWPAPRKMERAAIIGDKPF

Sequences:

>Translated_280_residues
MRAQPLTCNIGAEVSGVSLADAARDDALFAEIKSLLLTHKVLFLRDQEISRADHVAFARRFGELEDHPVAGSDPDHPGLV
QIYRSDKRENYENSYHTDGSWRETPPMGCVLRCIECPPVGGDTIWVNMAAAYEHLPEEIKQRIAGLRAKHSIEHSFGAAM
SPEKRASLAAQYPMVEHPVVRTHPETGEKALYVCGFSTHFANFHTPENVRYGQDKTPGASHLLNYLISQAAIPEYQVRFR
WQPNSVAIWDNRCTQHYAVQDYWPAPRKMERAAIIGDKPF
>Mature_280_residues
MRAQPLTCNIGAEVSGVSLADAARDDALFAEIKSLLLTHKVLFLRDQEISRADHVAFARRFGELEDHPVAGSDPDHPGLV
QIYRSDKRENYENSYHTDGSWRETPPMGCVLRCIECPPVGGDTIWVNMAAAYEHLPEEIKQRIAGLRAKHSIEHSFGAAM
SPEKRASLAAQYPMVEHPVVRTHPETGEKALYVCGFSTHFANFHTPENVRYGQDKTPGASHLLNYLISQAAIPEYQVRFR
WQPNSVAIWDNRCTQHYAVQDYWPAPRKMERAAIIGDKPF

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=286, Percent_Identity=40.9090909090909, Blast_Score=201, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6322971, Length=281, Percent_Identity=28.4697508896797, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31563; Mature: 31563

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAQPLTCNIGAEVSGVSLADAARDDALFAEIKSLLLTHKVLFLRDQEISRADHVAFARR
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHH
FGELEDHPVAGSDPDHPGLVQIYRSDKRENYENSYHTDGSWRETPPMGCVLRCIECPPVG
HCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCC
GDTIWVNMAAAYEHLPEEIKQRIAGLRAKHSIEHSFGAAMSPEKRASLAAQYPMVEHPVV
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEE
RTHPETGEKALYVCGFSTHFANFHTPENVRYGQDKTPGASHLLNYLISQAAIPEYQVRFR
ECCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
WQPNSVAIWDNRCTQHYAVQDYWPAPRKMERAAIIGDKPF
ECCCCEEEECCCCCCCEEHHCCCCCCHHHHHHEECCCCCC
>Mature Secondary Structure
MRAQPLTCNIGAEVSGVSLADAARDDALFAEIKSLLLTHKVLFLRDQEISRADHVAFARR
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHH
FGELEDHPVAGSDPDHPGLVQIYRSDKRENYENSYHTDGSWRETPPMGCVLRCIECPPVG
HCCCCCCCCCCCCCCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCHHHHHHEECCCCCC
GDTIWVNMAAAYEHLPEEIKQRIAGLRAKHSIEHSFGAAMSPEKRASLAAQYPMVEHPVV
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEE
RTHPETGEKALYVCGFSTHFANFHTPENVRYGQDKTPGASHLLNYLISQAAIPEYQVRFR
ECCCCCCCCEEEEEECHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEE
WQPNSVAIWDNRCTQHYAVQDYWPAPRKMERAAIIGDKPF
ECCCCEEEECCCCCCCEEHHCCCCCCHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]