| Definition | Ralstonia eutropha H16 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008314 |
| Length | 2,912,490 |
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The map label for this gene is yxbG [H]
Identifier: 116694552
GI number: 116694552
Start: 674133
End: 674918
Strand: Direct
Name: yxbG [H]
Synonym: H16_B0601
Alternate gene names: 116694552
Gene position: 674133-674918 (Clockwise)
Preceding gene: 116694551
Following gene: 116694553
Centisome position: 23.15
GC content: 68.45
Gene sequence:
>786_bases ATGGAATACCCGTATAGCCTGTTCGACCTGCGCGGCAAGGTTGCCGCCATCACCGGTGCCGCGCGCGGCATCGGCGCGGA AACCGCCCGCGTGCTGGCGGCGGCCGGCGCGAAGGTCGCGGTACTAGACGTGCTGGAAGCCGACGGCAAGGCCACCGCGG AAGCGATATGCGCCGAAGGCGGCGAGGCCGAGTTCTGGAAGCTCGACGTCACCAGCGAAAGCGACGTGAAGCGCGTGTTC GCGGAGATCGCGGCGCGCTTCGGCGGCCTCGGCATCCTGGTGAACAACGCCGGCATCGAAGGGCCCAATGCGCCGACCCA TGAGCTCGCGCTGGAGCAATGGCAGCAGGTCATGGCCGTGAACGTGACCGGCACCTTCCTGTGCACCAAGCACGCCATCG GTCACATGGAGCGCGCCGGCGGCGGCGCCATTGTCAACGTGTCGTCGATGTACGGCATCGCCGGCGGGCCGGACGTGCCG CCTTATCACGCATCCAAGGCCGCGGTGCGGATGATGGCCAAGACCGATGCCATGCTCTATGCCGGCAAGGGGATTCGCGC CAACTCGATCCATCCCGGCTATATCCGCACGCCGATGCTCGAACACGTGGCCCAGGCCTCGGGGCAGGGCGAGGCGCTGT TTGACTACCTGGGTGGACAGACCCCCGCGGGCAAGGTGGGCCAGCCCCGCGACATCGCCGCGGGCATCCTGTACCTCGTG TCCGACGCCGGGCGCTACGTCACCGGCGCCGAGCTGGTGATCGACGGCGGCTACACCGCACGCTAG
Upstream 100 bases:
>100_bases ATATTTCAACCGTGAATGTATCGGCTTCCTGGCGGATACCGCCCAGGGCGGGGCGGCATAATTGGCTCGCACGTCCACAC AAGAAGACCCAGGAGACATC
Downstream 100 bases:
>100_bases AACCACCAGACAAGGAGAACCCCATGCCCGATAGCGCCGCGATGAAAGCCACGCTGCTCGCCTATGTCGATCGTTTCAAT GCCGGTGACGCGCAGGGCGT
Product: cyclohexanol dehydrogenase
Products: D-Gluconate; Nicotinamide adenine dinucleotide phosphate [C]
Alternate protein names: NA
Number of amino acids: Translated: 261; Mature: 261
Protein sequence:
>261_residues MEYPYSLFDLRGKVAAITGAARGIGAETARVLAAAGAKVAVLDVLEADGKATAEAICAEGGEAEFWKLDVTSESDVKRVF AEIAARFGGLGILVNNAGIEGPNAPTHELALEQWQQVMAVNVTGTFLCTKHAIGHMERAGGGAIVNVSSMYGIAGGPDVP PYHASKAAVRMMAKTDAMLYAGKGIRANSIHPGYIRTPMLEHVAQASGQGEALFDYLGGQTPAGKVGQPRDIAAGILYLV SDAGRYVTGAELVIDGGYTAR
Sequences:
>Translated_261_residues MEYPYSLFDLRGKVAAITGAARGIGAETARVLAAAGAKVAVLDVLEADGKATAEAICAEGGEAEFWKLDVTSESDVKRVF AEIAARFGGLGILVNNAGIEGPNAPTHELALEQWQQVMAVNVTGTFLCTKHAIGHMERAGGGAIVNVSSMYGIAGGPDVP PYHASKAAVRMMAKTDAMLYAGKGIRANSIHPGYIRTPMLEHVAQASGQGEALFDYLGGQTPAGKVGQPRDIAAGILYLV SDAGRYVTGAELVIDGGYTAR >Mature_261_residues MEYPYSLFDLRGKVAAITGAARGIGAETARVLAAAGAKVAVLDVLEADGKATAEAICAEGGEAEFWKLDVTSESDVKRVF AEIAARFGGLGILVNNAGIEGPNAPTHELALEQWQQVMAVNVTGTFLCTKHAIGHMERAGGGAIVNVSSMYGIAGGPDVP PYHASKAAVRMMAKTDAMLYAGKGIRANSIHPGYIRTPMLEHVAQASGQGEALFDYLGGQTPAGKVGQPRDIAAGILYLV SDAGRYVTGAELVIDGGYTAR
Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=34.6491228070175, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=30.5555555555556, Blast_Score=114, Evalue=1e-25, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=32.1705426356589, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=31.0204081632653, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI31542939, Length=243, Percent_Identity=28.8065843621399, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=27.7992277992278, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=31.4176245210728, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=33.4645669291339, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=29.0196078431373, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.3186813186813, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI10190704, Length=254, Percent_Identity=30.7086614173228, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.5193798449612, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI5031737, Length=263, Percent_Identity=26.9961977186312, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=29.6153846153846, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI224922801, Length=166, Percent_Identity=31.3253012048193, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI209862901, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI19923983, Length=208, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI4504503, Length=209, Percent_Identity=30.1435406698565, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI186928839, Length=209, Percent_Identity=32.5358851674641, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI20149619, Length=251, Percent_Identity=29.4820717131474, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI4557649, Length=204, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI302344755, Length=104, Percent_Identity=34.6153846153846, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI7706318, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI119392083, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=29.1457286432161, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI40548397, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI214010158, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI214010156, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI22758144, Length=200, Percent_Identity=31, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=33.3333333333333, Blast_Score=137, Evalue=8e-34, Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=32.295719844358, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=31.2741312741313, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=36, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=32.8, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=34.5098039215686, Blast_Score=117, Evalue=8e-28, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.0483870967742, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=32.4110671936759, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=33.8709677419355, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789378, Length=241, Percent_Identity=31.5352697095436, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=31.9672131147541, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=26.7716535433071, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=29.2490118577075, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=26.8817204301075, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=34.4, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=32.4324324324324, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=35.3174603174603, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17560676, Length=266, Percent_Identity=31.203007518797, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=32.421875, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=32.089552238806, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17538182, Length=264, Percent_Identity=33.7121212121212, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=33.4600760456274, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=30.4182509505703, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=29.3893129770992, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=31.5384615384615, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.7709923664122, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=32.3420074349442, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538486, Length=258, Percent_Identity=30.6201550387597, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=31.6981132075472, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.957528957529, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=31.4176245210728, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=30.8300395256917, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.7984790874525, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=31.9587628865979, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=30.2788844621514, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=29.811320754717, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=29.8850574712644, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=30.3846153846154, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=29.8850574712644, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=29.0836653386454, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.2868525896414, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=29.277566539924, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203117, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17564282, Length=211, Percent_Identity=29.8578199052133, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71982365, Length=144, Percent_Identity=32.6388888888889, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17555612, Length=213, Percent_Identity=30.5164319248826, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=27.5590551181102, Blast_Score=75, Evalue=7e-15, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=34, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=35.408560311284, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.9365079365079, Blast_Score=117, Evalue=9e-27, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=31.7460317460317, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=31.25, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=34.9206349206349, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=33.9920948616601, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI281364892, Length=202, Percent_Identity=31.6831683168317, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI17737361, Length=237, Percent_Identity=31.2236286919831, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI28571387, Length=247, Percent_Identity=29.9595141700405, Blast_Score=81, Evalue=9e-16, Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=30.5882352941176, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24665243, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI221331218, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI281364494, Length=202, Percent_Identity=32.1782178217822, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=31.6582914572864, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24665247, Length=259, Percent_Identity=28.1853281853282, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI221331216, Length=259, Percent_Identity=28.1853281853282, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24640492, Length=195, Percent_Identity=29.7435897435897, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=28.780487804878, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=33.6842105263158, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI21357673, Length=194, Percent_Identity=31.4432989690722, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24648944, Length=254, Percent_Identity=28.740157480315, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007236, Length=243, Percent_Identity=27.9835390946502, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24665264, Length=205, Percent_Identity=27.8048780487805, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355631, Length=159, Percent_Identity=30.188679245283, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24663911, Length=204, Percent_Identity=28.4313725490196, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007234, Length=239, Percent_Identity=33.4728033472803, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.69 [C]
Molecular weight: Translated: 27063; Mature: 27063
Theoretical pI: Translated: 5.95; Mature: 5.95
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEYPYSLFDLRGKVAAITGAARGIGAETARVLAAAGAKVAVLDVLEADGKATAEAICAEG CCCCCCHHHHCCCEEEEECHHCCCCHHHHHHHHHCCCEEEEEEEHHCCCCHHHHHHHCCC GEAEFWKLDVTSESDVKRVFAEIAARFGGLGILVNNAGIEGPNAPTHELALEQWQQVMAV CCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEEE NVTGTFLCTKHAIGHMERAGGGAIVNVSSMYGIAGGPDVPPYHASKAAVRMMAKTDAMLY CCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHCEEEE AGKGIRANSIHPGYIRTPMLEHVAQASGQGEALFDYLGGQTPAGKVGQPRDIAAGILYLV ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH SDAGRYVTGAELVIDGGYTAR HCCCCEEECCEEEEECCCCCC >Mature Secondary Structure MEYPYSLFDLRGKVAAITGAARGIGAETARVLAAAGAKVAVLDVLEADGKATAEAICAEG CCCCCCHHHHCCCEEEEECHHCCCCHHHHHHHHHCCCEEEEEEEHHCCCCHHHHHHHCCC GEAEFWKLDVTSESDVKRVFAEIAARFGGLGILVNNAGIEGPNAPTHELALEQWQQVMAV CCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHEEE NVTGTFLCTKHAIGHMERAGGGAIVNVSSMYGIAGGPDVPPYHASKAAVRMMAKTDAMLY CCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHCEEEE AGKGIRANSIHPGYIRTPMLEHVAQASGQGEALFDYLGGQTPAGKVGQPRDIAAGILYLV ECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHH SDAGRYVTGAELVIDGGYTAR HCCCCEEECCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NAD+; NADH; NADP+; NADPH [C]
Metal ions: Mn2+ [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.02 {NADP+}} 20 {D-gluconate}} 0.006 {NADPH}} 0.9 {5-keto-D-gluconate}} [C]
Substrates: 5-Dehydro-D-gluconate; H+; Nicotinamide adenine dinucleotide phosphate - reduced [C]
Specific reaction: 5-Dehydro-D-gluconate + H+ + Nicotinamide adenine dinucleotide phosphate - reduced <==> D-Gluconate + Nicotinamide adenine dinucleotide phosphate [C]
General reaction: Redox reaction [C]
Inhibitor: Cd2+; Cs2+; Cu2+; Divalent metal ions; Hg2+; Ni2+; p-Chloromercuribenzoate; Sn2+; Sulfhydryl reagents [C]
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7584049; 9384377 [H]