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The map label for this gene is poxR [H]

Identifier: 116694489

GI number: 116694489

Start: 608981

End: 610708

Strand: Direct

Name: poxR [H]

Synonym: H16_B0538

Alternate gene names: 116694489

Gene position: 608981-610708 (Clockwise)

Preceding gene: 116694488

Following gene: 116694490

Centisome position: 20.91

GC content: 69.62

Gene sequence:

>1728_bases
ATGAGCAGTTCAACCGACAAGTTCTCGGCCACCATGCGCGATGGCCTGGCCGATCTTGCCCGCCGCCTGCGCTTCGCCAT
GGAGGAGGGTGCGATCTGGCTGGACGAGCAGCGCATGATCCTGATCCATACCGCCGCCCTGGGCGCGCTGCGCAAGGAAC
TGGTGGACACCCTGGGCATGGAGCGCGCGCGCGGCCTGTTCATGCGCATGGGCTTCCATTCGGGCATGCGCGATGCGGAG
GTCGCGCGCAAGCTGCGCGCCGGCCACAGCGACTTCGGCCAGCTGGAGATCGGGCCCTGCCTGCATACCATCGAGGGGGT
GGTGCGGGTCACGCCGGTCAAGGTCGACATCGACATCGCCGCCGGCATCTACGATGGCGAATTCCTGTGGGAAGACTCCT
TCGAGGGCGACGTCCACCGCCAGCTGTTCGGCATCGTCGACGAGCCTGCCTGCTGGATGCAGATCGGCTACGCCACCGGC
TACACCTCGGCGCTGATGGGGCGCACCATCCTGTACCGCGAGGTCGAGTGCATCGCCTGCGGCCATCCGCACTGCCGCAT
CATCGGCAAGCCGGTGGAAGCCTGGGAAGACGGCACGCAGGCGCTGGCGCTGTACCAGCCCGATCCCGTGATCGAAACCA
TCATCGCCTTGCAGAGCGAGGTAGAGCACCTGCGCGCGCTGCAGGGCACCCCGGCCACGCCGGCCGACCTGGTCGGCACC
TCGCCCGGCTTCCGTGCCGCCTGGGGCCTGCTGCAGCGGGCCGCGGCCAGCAACGTGACGGTGCTGCTGCTGGGCGAGAC
CGGCGTGGGCAAGGAGCGGTTCGCGCAGGCGCTGCACAGCGTGAGCGGGCGCGCCGACAAGCCCTTCATTGCCGTGAACT
GCGCGGCGATTCCCGATGAGCTGATCGAGTCCGAGCTGTTCGGCGTGGAAAAGGGCGCCTTCACCGGCGCCAGCCAGTCG
CGCCCCGGGCGCTTCGAGCGTGCGCATGGCGGCACGCTGTTCCTGGACGAACTGGGCGAGCTGTCGGCCTCGGCCCAGTC
CAAGCTGCTGCGCGTGCTGCAGGAAGGCGAGGTCGAGCGCGTGGGCGGCACCGGCACGCGCAAGGTGGATGTGCGGCTGG
TGGCCGCCACCAATGTCGACCTGGCCGAAGCCGTGAAGCAGGGCACCTTCCGCAAGGACCTGTACTACCGCCTCAACGTC
TACCCGGTCACGATCCCGCCGCTGCGCGAGCGCCTGGACGACATCCGGCCGCTGGCCGAGCGCTTCGTGGCCCGCTACGG
CGCGCGCCACGGCAAGCGCATCGTCGGCATCACCGACCGCGCGCTGGCCGAGCTGCGCCACTATGACTGGCCCGGCAATG
TGCGCGAACTGGAGAACGTGATCGAGCGCGGCGTGATCCTGGCCAGCCAGGGCGGCCAGATCACCGCCGACCACCTGTTC
CTGCCGGGCACCGTGGCACCGGTGGTGGATACCGCGCCGCGGCTGGGCGCGGGCGGCACCTTGCCAGACCTGCGCGAAGC
CGCGGTCCATGCGCTGCTGGACCAGATGTCAGAGCAGCAGCTGGCGCTGGGCGACGTCGAGACCGTGCTGATGGAGGCGG
CCATGCAGCGCGCCGACGGCAACATGAGCCAGGCGGCGCGGTTGCTCGGCATTACGCGGCCGCAGCTGGCGTATCGGTGG
AAGATGCGCGGTACGCGTGCCGGTAACGGGCACGGCAACGGTAACTGA

Upstream 100 bases:

>100_bases
TGTCATTGCCCTGCCCCCGTCTCCCTGGCACATAATGTGCGTAAGATGCCAGCCGAAAGGCACACTCGAGCGGATCACCC
GCCGGCACTGAGGGGAGACA

Downstream 100 bases:

>100_bases
CGCCGTTTCCTCGCCTCAAGTGCCGAGGGTTTGCTCCCCTCTCCCGCTTGCGGGAGAGGGAGCGCGCCGGTGGTCATCAA
CATCGATCGCGTCTTCCACG

Product: phenol-degradative gene activator

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSSSTDKFSATMRDGLADLARRLRFAMEEGAIWLDEQRMILIHTAALGALRKELVDTLGMERARGLFMRMGFHSGMRDAE
VARKLRAGHSDFGQLEIGPCLHTIEGVVRVTPVKVDIDIAAGIYDGEFLWEDSFEGDVHRQLFGIVDEPACWMQIGYATG
YTSALMGRTILYREVECIACGHPHCRIIGKPVEAWEDGTQALALYQPDPVIETIIALQSEVEHLRALQGTPATPADLVGT
SPGFRAAWGLLQRAAASNVTVLLLGETGVGKERFAQALHSVSGRADKPFIAVNCAAIPDELIESELFGVEKGAFTGASQS
RPGRFERAHGGTLFLDELGELSASAQSKLLRVLQEGEVERVGGTGTRKVDVRLVAATNVDLAEAVKQGTFRKDLYYRLNV
YPVTIPPLRERLDDIRPLAERFVARYGARHGKRIVGITDRALAELRHYDWPGNVRELENVIERGVILASQGGQITADHLF
LPGTVAPVVDTAPRLGAGGTLPDLREAAVHALLDQMSEQQLALGDVETVLMEAAMQRADGNMSQAARLLGITRPQLAYRW
KMRGTRAGNGHGNGN

Sequences:

>Translated_575_residues
MSSSTDKFSATMRDGLADLARRLRFAMEEGAIWLDEQRMILIHTAALGALRKELVDTLGMERARGLFMRMGFHSGMRDAE
VARKLRAGHSDFGQLEIGPCLHTIEGVVRVTPVKVDIDIAAGIYDGEFLWEDSFEGDVHRQLFGIVDEPACWMQIGYATG
YTSALMGRTILYREVECIACGHPHCRIIGKPVEAWEDGTQALALYQPDPVIETIIALQSEVEHLRALQGTPATPADLVGT
SPGFRAAWGLLQRAAASNVTVLLLGETGVGKERFAQALHSVSGRADKPFIAVNCAAIPDELIESELFGVEKGAFTGASQS
RPGRFERAHGGTLFLDELGELSASAQSKLLRVLQEGEVERVGGTGTRKVDVRLVAATNVDLAEAVKQGTFRKDLYYRLNV
YPVTIPPLRERLDDIRPLAERFVARYGARHGKRIVGITDRALAELRHYDWPGNVRELENVIERGVILASQGGQITADHLF
LPGTVAPVVDTAPRLGAGGTLPDLREAAVHALLDQMSEQQLALGDVETVLMEAAMQRADGNMSQAARLLGITRPQLAYRW
KMRGTRAGNGHGNGN
>Mature_574_residues
SSSTDKFSATMRDGLADLARRLRFAMEEGAIWLDEQRMILIHTAALGALRKELVDTLGMERARGLFMRMGFHSGMRDAEV
ARKLRAGHSDFGQLEIGPCLHTIEGVVRVTPVKVDIDIAAGIYDGEFLWEDSFEGDVHRQLFGIVDEPACWMQIGYATGY
TSALMGRTILYREVECIACGHPHCRIIGKPVEAWEDGTQALALYQPDPVIETIIALQSEVEHLRALQGTPATPADLVGTS
PGFRAAWGLLQRAAASNVTVLLLGETGVGKERFAQALHSVSGRADKPFIAVNCAAIPDELIESELFGVEKGAFTGASQSR
PGRFERAHGGTLFLDELGELSASAQSKLLRVLQEGEVERVGGTGTRKVDVRLVAATNVDLAEAVKQGTFRKDLYYRLNVY
PVTIPPLRERLDDIRPLAERFVARYGARHGKRIVGITDRALAELRHYDWPGNVRELENVIERGVILASQGGQITADHLFL
PGTVAPVVDTAPRLGAGGTLPDLREAAVHALLDQMSEQQLALGDVETVLMEAAMQRADGNMSQAARLLGITRPQLAYRWK
MRGTRAGNGHGNGN

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=395, Percent_Identity=39.4936708860759, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1790437, Length=344, Percent_Identity=43.8953488372093, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87082117, Length=227, Percent_Identity=55.5066079295154, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789087, Length=258, Percent_Identity=49.6124031007752, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI87082152, Length=285, Percent_Identity=46.6666666666667, Blast_Score=235, Evalue=6e-63,
Organism=Escherichia coli, GI1790299, Length=377, Percent_Identity=40.8488063660477, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=42.0062695924765, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=43.2515337423313, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786524, Length=340, Percent_Identity=41.7647058823529, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788905, Length=310, Percent_Identity=42.258064516129, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1787583, Length=280, Percent_Identity=40, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI87081858, Length=373, Percent_Identity=34.5844504021448, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1789828, Length=236, Percent_Identity=38.9830508474576, Blast_Score=138, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 62727; Mature: 62595

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSTDKFSATMRDGLADLARRLRFAMEEGAIWLDEQRMILIHTAALGALRKELVDTLGM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHHHHHHHHHHHHCH
ERARGLFMRMGFHSGMRDAEVARKLRAGHSDFGQLEIGPCLHTIEGVVRVTPVKVDIDIA
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCEEEEEEEEEEEEE
AGIYDGEFLWEDSFEGDVHRQLFGIVDEPACWMQIGYATGYTSALMGRTILYREVECIAC
ECEECCCEEECCCCCCHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHHHHEEEEEEC
GHPHCRIIGKPVEAWEDGTQALALYQPDPVIETIIALQSEVEHLRALQGTPATPADLVGT
CCCCEEEECCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC
SPGFRAAWGLLQRAAASNVTVLLLGETGVGKERFAQALHSVSGRADKPFIAVNCAAIPDE
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHH
LIESELFGVEKGAFTGASQSRPGRFERAHGGTLFLDELGELSASAQSKLLRVLQEGEVER
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEE
VGGTGTRKVDVRLVAATNVDLAEAVKQGTFRKDLYYRLNVYPVTIPPLRERLDDIRPLAE
CCCCCCEEEEEEEEEECCCHHHHHHHHCCCHHCEEEEEEEEEEECCHHHHHHHHHHHHHH
RFVARYGARHGKRIVGITDRALAELRHYDWPGNVRELENVIERGVILASQGGQITADHLF
HHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCEEEECCEE
LPGTVAPVVDTAPRLGAGGTLPDLREAAVHALLDQMSEQQLALGDVETVLMEAAMQRADG
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NMSQAARLLGITRPQLAYRWKMRGTRAGNGHGNGN
CHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SSSTDKFSATMRDGLADLARRLRFAMEEGAIWLDEQRMILIHTAALGALRKELVDTLGM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHHHHHHHHHHHHCH
ERARGLFMRMGFHSGMRDAEVARKLRAGHSDFGQLEIGPCLHTIEGVVRVTPVKVDIDIA
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCEEEEEEEEEEEEE
AGIYDGEFLWEDSFEGDVHRQLFGIVDEPACWMQIGYATGYTSALMGRTILYREVECIAC
ECEECCCEEECCCCCCHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHHHHEEEEEEC
GHPHCRIIGKPVEAWEDGTQALALYQPDPVIETIIALQSEVEHLRALQGTPATPADLVGT
CCCCEEEECCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCC
SPGFRAAWGLLQRAAASNVTVLLLGETGVGKERFAQALHSVSGRADKPFIAVNCAAIPDE
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHH
LIESELFGVEKGAFTGASQSRPGRFERAHGGTLFLDELGELSASAQSKLLRVLQEGEVER
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCEEE
VGGTGTRKVDVRLVAATNVDLAEAVKQGTFRKDLYYRLNVYPVTIPPLRERLDDIRPLAE
CCCCCCEEEEEEEEEECCCHHHHHHHHCCCHHCEEEEEEEEEEECCHHHHHHHHHHHHHH
RFVARYGARHGKRIVGITDRALAELRHYDWPGNVRELENVIERGVILASQGGQITADHLF
HHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCEEEECCEE
LPGTVAPVVDTAPRLGAGGTLPDLREAAVHALLDQMSEQQLALGDVETVLMEAAMQRADG
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NMSQAARLLGITRPQLAYRWKMRGTRAGNGHGNGN
CHHHHHHHHCCCCCHHEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]