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The map label for this gene is ycgM [C]

Identifier: 116694398

GI number: 116694398

Start: 506403

End: 507308

Strand: Direct

Name: ycgM [C]

Synonym: H16_B0447

Alternate gene names: 116694398

Gene position: 506403-507308 (Clockwise)

Preceding gene: 116694391

Following gene: 116694399

Centisome position: 17.39

GC content: 61.92

Gene sequence:

>906_bases
ATGAAATATCAACTGTTCAACTACGAAGGCCGCGATGGCACGATCAACGTCGGCGTGCACGCGGACAGCCGGCATGTGCA
ATTCGCCGCAGGCACCGTTGACGGCCTGTTGCAGGACTGGCCCGCCGCGCAGCTACGCATTGCGCGCTTCATTGCGCAAC
TGCCGCTGGCCGCCGAGACGATGGAGCCCGCACAGATCCGCTTCCTGCCGCCGCTGAGCCAGCCCGGTGTCATCTATGGG
GCAGGGGCGAACTACCGCGACCATGTCGTGGCCATGGCAAAGGCCGTCAATATGGACCTGACGACAGATCCGAAGGCCGA
TGGCGTACCGCCGTGGCACTTCATCAAGGCCGGCCGGGGAACACTGTCCGCCCACCGCCAGGCGCTGCCTTATCCCTCGC
ACACGCGAATGCTCGACTGGGAGGCTGAACTTGCGGTGGTGATCGGCAAGGCATGCCGCAACATCTCGCCGGGCGACGCG
CTCGACTGTGTAGCGGGATATACCATTGCCAACGACCTGTCGGCACGCGACAACCTGCGTCGCGAGCAGGTCGATGCAAG
TTCGCCGTTCCGCTTTGACTGGATCGGCCACAAGTGCTTTGAAGGCTCCTGTCCCCTCGGTCCTTACCTGACTCCCGCGG
CTTTCGTGGCGTCCCCTGAAGCGCTGGATATCAAGCTTTGGGTCAATGACGAACTCAAGCAGAACTCGAATACGTCCAAT
CACCTTTACACGGTTGCCGAGCAGATCGCCTACTTGAGCGAGCGGCTCACGTTGTATCCGGGCGATGTGCTGCTCACCGG
GACGCCTGCCGGCGTTGGCATGGAATCGGGAGTCTTCCTGAAGCGCGGCGACAGTATCCGCGTCTGGATTGATGGACTGG
GCGAACTGGAGACATCGTTGCAGTAG

Upstream 100 bases:

>100_bases
GTTCTGGCCGGGCATTACGCCAGTTTATACATTGACATCATCCAGGACGGCTGGTTTGGCGGACACGTAAGCGCCAGAAT
CCCCCAACCAGTGAGGTGAA

Downstream 100 bases:

>100_bases
GGCAATACCACGGGCGGCGTTCGCCGCCTGACATGGGGAGCCGTTCAGGCTCGCGTCCGCACGGGCACCACATAGAGTGC
CTGACGGGCAATGACAATTC

Product: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKYQLFNYEGRDGTINVGVHADSRHVQFAAGTVDGLLQDWPAAQLRIARFIAQLPLAAETMEPAQIRFLPPLSQPGVIYG
AGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGRGTLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDA
LDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSN
HLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGMESGVFLKRGDSIRVWIDGLGELETSLQ

Sequences:

>Translated_301_residues
MKYQLFNYEGRDGTINVGVHADSRHVQFAAGTVDGLLQDWPAAQLRIARFIAQLPLAAETMEPAQIRFLPPLSQPGVIYG
AGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGRGTLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDA
LDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSN
HLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGMESGVFLKRGDSIRVWIDGLGELETSLQ
>Mature_301_residues
MKYQLFNYEGRDGTINVGVHADSRHVQFAAGTVDGLLQDWPAAQLRIARFIAQLPLAAETMEPAQIRFLPPLSQPGVIYG
AGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGRGTLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDA
LDCVAGYTIANDLSARDNLRREQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSN
HLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGMESGVFLKRGDSIRVWIDGLGELETSLQ

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=256, Percent_Identity=37.5, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI156231349, Length=257, Percent_Identity=36.9649805447471, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI215422413, Length=222, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI13654274, Length=216, Percent_Identity=34.2592592592593, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI66348062, Length=216, Percent_Identity=34.7222222222222, Blast_Score=108, Evalue=4e-24,
Organism=Escherichia coli, GI1787428, Length=211, Percent_Identity=35.0710900473934, Blast_Score=108, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=195, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324161, Length=153, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28572127, Length=233, Percent_Identity=35.1931330472103, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24663695, Length=248, Percent_Identity=32.6612903225806, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571789, Length=230, Percent_Identity=33.0434782608696, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 32920; Mature: 32920

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQLFNYEGRDGTINVGVHADSRHVQFAAGTVDGLLQDWPAAQLRIARFIAQLPLAAET
CCEEEEEECCCCCEEEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCC
MEPAQIRFLPPLSQPGVIYGAGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGRG
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCC
TLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLR
CHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCHHHHHH
REQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSN
HHHCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHCCCCEEEEEEEECCHHHCCCCCCH
HLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGMESGVFLKRGDSIRVWIDGLGELETSL
HHHHHHHHHHHHHHCEEECCCCEEEECCCCCCCCCCCEEEEECCEEEEEECCCCCHHHCC
Q
C
>Mature Secondary Structure
MKYQLFNYEGRDGTINVGVHADSRHVQFAAGTVDGLLQDWPAAQLRIARFIAQLPLAAET
CCEEEEEECCCCCEEEEEEECCCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHCCCCCCC
MEPAQIRFLPPLSQPGVIYGAGANYRDHVVAMAKAVNMDLTTDPKADGVPPWHFIKAGRG
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEECCCC
TLSAHRQALPYPSHTRMLDWEAELAVVIGKACRNISPGDALDCVAGYTIANDLSARDNLR
CHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCHHHHHHCCHHHCCCCHHHHHH
REQVDASSPFRFDWIGHKCFEGSCPLGPYLTPAAFVASPEALDIKLWVNDELKQNSNTSN
HHHCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHCCCCEEEEEEEECCHHHCCCCCCH
HLYTVAEQIAYLSERLTLYPGDVLLTGTPAGVGMESGVFLKRGDSIRVWIDGLGELETSL
HHHHHHHHHHHHHHCEEECCCCEEEECCCCCCCCCCCEEEEECCEEEEEECCCCCHHHCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]