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The map label for this gene is mtaD [H]

Identifier: 116694384

GI number: 116694384

Start: 490910

End: 492331

Strand: Direct

Name: mtaD [H]

Synonym: H16_B0432

Alternate gene names: 116694384

Gene position: 490910-492331 (Clockwise)

Preceding gene: 116694383

Following gene: 116694385

Centisome position: 16.86

GC content: 60.83

Gene sequence:

>1422_bases
ATGATGGTCGCGGCAACCGGGATCCCCTCGCTTGTCGCTTCGGCATCGGCTTCGGCGGGAGGCGGCATGCCATCCGCGGC
GTCCGGAGCCCGTCGAGGCACCTACCTGATCAAGAACGGCATGGTCATCACGGTCGACCGGAAGAATGGCGTCATGCCAC
GCGCCGACATCTTGATTCGAAACGGCGTGATCGAGAAGATCGGTCGGGGTCTGAGCACGGCCGGCGCGCAGACGATCGAT
GCCGCGGACATGATCGTCATGCCCGGCTTCGTCAACTCTCACTACCATATGTGGAGCGCGATCGGACGCAGCTTCACCGC
GCGGAACGGCGGCTTCTCCTACTACCCGGCCAAGAGCGCCACATCCGCCTTGTACACGCCGGAGGACTTCTACAACAGCG
TGCTCCTTGCGTGCGCCGAACTAGCGAACGGCGGGACCACTACCGTGCACAACTGGTCGCATAACACCCGCTCCGCGGCC
CATGCGGATGCCGAACTTCGCGCGCACCAGCACTCTCTGCTGAGGGCCCGTTACTCGTACGGCCACATTGACAAGCTCCC
GGTAGACGAGGTGAACAGGTTCGGCGACCTTGCGCGCGTCCAGCGCAAATGGTTCGGTGCAAACTCCCCATTCGAAGGTT
TGGTGCACCTGGGACTGAATCTGCGTGGTCCGCAACAGAGCACCGATGCTGTCTTTCACGAGGAAATGAAGTTCGTCAAG
AAGAGTGGGCTTCCCGTAGCGATCCACGCGCCGCAGGAGTCGCCCAACAATGTCGATGCTGTCGACTACGAGAGGCGCGG
TTACCTCGGCCCCGATTTTATGATCGCGCATTACGTCCCGGCGACGACCGAGGACTTGATGGCGATGGCGCGCACGAAGA
CACCGCTCTCCTTTGCGACACATTCCGAACTCCGGCTCAGCAGCACGGGCGATGCCCGGGCTGCGCTGTTCGCGATGCGT
GCCGCGGGGCTGACTATCTCATTGTCGAGCGACGCGACGTCCATTGCCCCACCGGACATGTTCGAAATGATGCGTTTCAC
CTGGAACCTCGGGGTGCCCTGGGTTGGCACCCCCAGCGAGCGGGCAAGGGCGGTCAGCGTGCAAGAGGTGATCGAGATGG
CGACGATCAATGGAGCCATCGCGATGGGGATCGGCGACATCACTGGATCGATCACTGAAGGCAAGCGCGCAGACATCATT
CTGGTGCGGGCCAAGGATCTGAACATCTGGCCAATAGGCAATATCGAAACGGCGATTGTGCAGAGCGGCAGCGCCAGCAA
CGTCGACACGGTGTTAGTCGATGGCCGAATAATAAAGAGAAGCGGTCGCTTGCTAGCCTACAACGTGGACAGCATTGTTC
GCGGTGCTCAGCAGTCCTCCAATCGGATTCTCAATGCGGCTGATGAGATGATGAAGTTATGA

Upstream 100 bases:

>100_bases
CTCGAGACGAGTTGACCACAACCGTCTTCCTGCAATCCAAATCGCATCGGAAAGGAACATGAGAACAACCAGAAGAGAAT
TCGCCAAGGTCGCCGGCGCA

Downstream 100 bases:

>100_bases
GTAGTCTAAAGAGTGAGTGGGACGAACGCCGCCTTCTGTTCGAGATGAAATGCACACCGAACTCCCTCCGTGGACCAGGC
AGCGGGAGTTATTTGTCCGC

Product: cytosine deaminase or related metal-dependent hydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MMVAATGIPSLVASASASAGGGMPSAASGARRGTYLIKNGMVITVDRKNGVMPRADILIRNGVIEKIGRGLSTAGAQTID
AADMIVMPGFVNSHYHMWSAIGRSFTARNGGFSYYPAKSATSALYTPEDFYNSVLLACAELANGGTTTVHNWSHNTRSAA
HADAELRAHQHSLLRARYSYGHIDKLPVDEVNRFGDLARVQRKWFGANSPFEGLVHLGLNLRGPQQSTDAVFHEEMKFVK
KSGLPVAIHAPQESPNNVDAVDYERRGYLGPDFMIAHYVPATTEDLMAMARTKTPLSFATHSELRLSSTGDARAALFAMR
AAGLTISLSSDATSIAPPDMFEMMRFTWNLGVPWVGTPSERARAVSVQEVIEMATINGAIAMGIGDITGSITEGKRADII
LVRAKDLNIWPIGNIETAIVQSGSASNVDTVLVDGRIIKRSGRLLAYNVDSIVRGAQQSSNRILNAADEMMKL

Sequences:

>Translated_473_residues
MMVAATGIPSLVASASASAGGGMPSAASGARRGTYLIKNGMVITVDRKNGVMPRADILIRNGVIEKIGRGLSTAGAQTID
AADMIVMPGFVNSHYHMWSAIGRSFTARNGGFSYYPAKSATSALYTPEDFYNSVLLACAELANGGTTTVHNWSHNTRSAA
HADAELRAHQHSLLRARYSYGHIDKLPVDEVNRFGDLARVQRKWFGANSPFEGLVHLGLNLRGPQQSTDAVFHEEMKFVK
KSGLPVAIHAPQESPNNVDAVDYERRGYLGPDFMIAHYVPATTEDLMAMARTKTPLSFATHSELRLSSTGDARAALFAMR
AAGLTISLSSDATSIAPPDMFEMMRFTWNLGVPWVGTPSERARAVSVQEVIEMATINGAIAMGIGDITGSITEGKRADII
LVRAKDLNIWPIGNIETAIVQSGSASNVDTVLVDGRIIKRSGRLLAYNVDSIVRGAQQSSNRILNAADEMMKL
>Mature_473_residues
MMVAATGIPSLVASASASAGGGMPSAASGARRGTYLIKNGMVITVDRKNGVMPRADILIRNGVIEKIGRGLSTAGAQTID
AADMIVMPGFVNSHYHMWSAIGRSFTARNGGFSYYPAKSATSALYTPEDFYNSVLLACAELANGGTTTVHNWSHNTRSAA
HADAELRAHQHSLLRARYSYGHIDKLPVDEVNRFGDLARVQRKWFGANSPFEGLVHLGLNLRGPQQSTDAVFHEEMKFVK
KSGLPVAIHAPQESPNNVDAVDYERRGYLGPDFMIAHYVPATTEDLMAMARTKTPLSFATHSELRLSSTGDARAALFAMR
AAGLTISLSSDATSIAPPDMFEMMRFTWNLGVPWVGTPSERARAVSVQEVIEMATINGAIAMGIGDITGSITEGKRADII
LVRAKDLNIWPIGNIETAIVQSGSASNVDTVLVDGRIIKRSGRLLAYNVDSIVRGAQQSSNRILNAADEMMKL

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50852; Mature: 50852

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVAATGIPSLVASASASAGGGMPSAASGARRGTYLIKNGMVITVDRKNGVMPRADILIR
CEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCHHHEEEC
NGVIEKIGRGLSTAGAQTIDAADMIVMPGFVNSHYHMWSAIGRSFTARNGGFSYYPAKSA
CCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCEECCCCCEEECCCCCC
TSALYTPEDFYNSVLLACAELANGGTTTVHNWSHNTRSAAHADAELRAHQHSLLRARYSY
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCHHHHHHHHHHHHHHHHCC
GHIDKLPVDEVNRFGDLARVQRKWFGANSPFEGLVHLGLNLRGPQQSTDAVFHEEMKFVK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHH
KSGLPVAIHAPQESPNNVDAVDYERRGYLGPDFMIAHYVPATTEDLMAMARTKTPLSFAT
HCCCCEEEECCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECC
HSELRLSSTGDARAALFAMRAAGLTISLSSDATSIAPPDMFEMMRFTWNLGVPWVGTPSE
CCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
RARAVSVQEVIEMATINGAIAMGIGDITGSITEGKRADIILVRAKDLNIWPIGNIETAIV
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEE
QSGSASNVDTVLVDGRIIKRSGRLLAYNVDSIVRGAQQSSNRILNAADEMMKL
ECCCCCCCCEEEECCEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MMVAATGIPSLVASASASAGGGMPSAASGARRGTYLIKNGMVITVDRKNGVMPRADILIR
CEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCEEEEEECCCCCCCHHHEEEC
NGVIEKIGRGLSTAGAQTIDAADMIVMPGFVNSHYHMWSAIGRSFTARNGGFSYYPAKSA
CCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCEECCCCCEEECCCCCC
TSALYTPEDFYNSVLLACAELANGGTTTVHNWSHNTRSAAHADAELRAHQHSLLRARYSY
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCHHHHHHHHHHHHHHHHCC
GHIDKLPVDEVNRFGDLARVQRKWFGANSPFEGLVHLGLNLRGPQQSTDAVFHEEMKFVK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCHHHHHHHHHHHHHH
KSGLPVAIHAPQESPNNVDAVDYERRGYLGPDFMIAHYVPATTEDLMAMARTKTPLSFAT
HCCCCEEEECCCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECC
HSELRLSSTGDARAALFAMRAAGLTISLSSDATSIAPPDMFEMMRFTWNLGVPWVGTPSE
CCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
RARAVSVQEVIEMATINGAIAMGIGDITGSITEGKRADIILVRAKDLNIWPIGNIETAIV
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEE
QSGSASNVDTVLVDGRIIKRSGRLLAYNVDSIVRGAQQSSNRILNAADEMMKL
ECCCCCCCCEEEECCEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]