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The map label for this gene is pbuE [H]

Identifier: 116694382

GI number: 116694382

Start: 488822

End: 490072

Strand: Direct

Name: pbuE [H]

Synonym: H16_B0430

Alternate gene names: 116694382

Gene position: 488822-490072 (Clockwise)

Preceding gene: 116694381

Following gene: 116694383

Centisome position: 16.78

GC content: 62.67

Gene sequence:

>1251_bases
GTGAATTCCTCGACTTCGGCCGGCCCGCTGACCGGAGACGTGCGCAGCGATGCGCCCGTCACGGCATTGGAGATCGGCAT
GTTTCTTGTGCTGCTTGCCTCCTATGCGCTCAACGCGATGGACCGGCAGATCTTTCCGCTGATCGCCGCAGATGTGCGAA
GGGAGTTTGGGTTCGGCCTCGCCGACACCGGCCTGCTTTCGACCATCTTTACGCTCGGCATGGCACTAGCGGGGGTGCCG
ACAGGCTACCTGCTGGCGCGGTGGTCGCGCAAGGCCGTGCTCCAGATTGGCATCGCGATCTTCTCGCTTGGCACGCTGTT
GACTGCCTACTCGAGCGGCTTTGCCGACATGATCCTCTACCGCGCCGCTACTGGCATCGGCGAAGCGATGCAGCTGACTG
TGGTGATCGCCATCGCGGCGAGCTATTTCGCTCGCTTCCGCGCGACGGCCGTTGGGGCCATCAACTTCTCCTTCGGTGTC
GGAGCCATCGTGGGACCGCTGCTCGGTGGGCACCTGATCGGCATTGAGCGAAACTGGCGCTTGCCGCTGGTGGTGTTCGG
CCTGACCGGATTTGTCGCAATGGCGCTGATCGCGGCTACCGTGAGCAAGCGCATGACCGAAAAGGCCAGCGCGATCGCCA
CGCACATCGACACGCGCGGTGCAACCACGATGTGGAACCGCAACACGGCTCTCTTGACTGTGATGAGCATCATTGGCGGG
TTGTGCATCTATGGCTACCTCGGCATGTACCCCACGTTCCTGCGCGAGCATCTGCACTACACGCCGTCGGACACTGGTCG
CGTCATGAGTATCTTCGGGTGCGGCGTGTTCGCCTCCATCTTTGGCGGCTGGCTTGGCGACCGCTTCCACCCCAAGCTTG
TGTTGTCGCTGAGCTTTGCGGGGACCGGGCTGCTCGGCTTCCTTCTGTTCTCGGGGCCGACGGGCATGTTGGTCCAATCG
GTGCTGTCATTCGTGTGGGGGCTGGTGGTAAGTGGCGTGCTGTACGTGAACCTGGCCGGCTACCATATCAAGTCCGTGCG
CTCTTCGCTCACGAATCGGGCCACCGGTGTCTTTGTCACGACGCTCTACGGCGCGGGCGCTTTCGCGGGCTACATCATCG
GCGGCATCGCGGCGCGCTTTGGCTGGAGCACCGCCGGCTTTGCGCAGATCACCTTGCTATCGGTCTTCGGAATAGTACTC
ACCGTGCTACTGCGGACCGACCGGATGTCCTTGCCTGTGCGTAAGCCATGA

Upstream 100 bases:

>100_bases
TCCTCGATTGGTATAAGGCAGCGCGCGCGGCCTCATAGCCGGATCCGTACATCGCCAGAAACTCGAACAAATCTCTCGCT
TGACGAGAAGGAGACAACAC

Downstream 100 bases:

>100_bases
CGCCGGCCGAATGGGTGCTGCTCGGTGGCGCTGCGACTTTCGCCGGGACGCTGAATGCGGTGGCAGGCGGCGGTAGTTTC
CTGACACTGCCGGCCTTGGC

Product: MFS family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MNSSTSAGPLTGDVRSDAPVTALEIGMFLVLLASYALNAMDRQIFPLIAADVRREFGFGLADTGLLSTIFTLGMALAGVP
TGYLLARWSRKAVLQIGIAIFSLGTLLTAYSSGFADMILYRAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGV
GAIVGPLLGGHLIGIERNWRLPLVVFGLTGFVAMALIAATVSKRMTEKASAIATHIDTRGATTMWNRNTALLTVMSIIGG
LCIYGYLGMYPTFLREHLHYTPSDTGRVMSIFGCGVFASIFGGWLGDRFHPKLVLSLSFAGTGLLGFLLFSGPTGMLVQS
VLSFVWGLVVSGVLYVNLAGYHIKSVRSSLTNRATGVFVTTLYGAGAFAGYIIGGIAARFGWSTAGFAQITLLSVFGIVL
TVLLRTDRMSLPVRKP

Sequences:

>Translated_416_residues
MNSSTSAGPLTGDVRSDAPVTALEIGMFLVLLASYALNAMDRQIFPLIAADVRREFGFGLADTGLLSTIFTLGMALAGVP
TGYLLARWSRKAVLQIGIAIFSLGTLLTAYSSGFADMILYRAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGV
GAIVGPLLGGHLIGIERNWRLPLVVFGLTGFVAMALIAATVSKRMTEKASAIATHIDTRGATTMWNRNTALLTVMSIIGG
LCIYGYLGMYPTFLREHLHYTPSDTGRVMSIFGCGVFASIFGGWLGDRFHPKLVLSLSFAGTGLLGFLLFSGPTGMLVQS
VLSFVWGLVVSGVLYVNLAGYHIKSVRSSLTNRATGVFVTTLYGAGAFAGYIIGGIAARFGWSTAGFAQITLLSVFGIVL
TVLLRTDRMSLPVRKP
>Mature_416_residues
MNSSTSAGPLTGDVRSDAPVTALEIGMFLVLLASYALNAMDRQIFPLIAADVRREFGFGLADTGLLSTIFTLGMALAGVP
TGYLLARWSRKAVLQIGIAIFSLGTLLTAYSSGFADMILYRAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGV
GAIVGPLLGGHLIGIERNWRLPLVVFGLTGFVAMALIAATVSKRMTEKASAIATHIDTRGATTMWNRNTALLTVMSIIGG
LCIYGYLGMYPTFLREHLHYTPSDTGRVMSIFGCGVFASIFGGWLGDRFHPKLVLSLSFAGTGLLGFLLFSGPTGMLVQS
VLSFVWGLVVSGVLYVNLAGYHIKSVRSSLTNRATGVFVTTLYGAGAFAGYIIGGIAARFGWSTAGFAQITLLSVFGIVL
TVLLRTDRMSLPVRKP

Specific function: Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine base analogs 2,6- diaminopurine and 6-mercaptopurine. Therefore plays a role in maintaining t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. PbuE (TC 2.A.1.2.25) subfamily [H]

Homologues:

Organism=Drosophila melanogaster, GI24654044, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24654041, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654039, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864456, Length=162, Percent_Identity=32.0987654320988, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654037, Length=162, Percent_Identity=32.0987654320988, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44067; Mature: 44067

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSTSAGPLTGDVRSDAPVTALEIGMFLVLLASYALNAMDRQIFPLIAADVRREFGFGL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADTGLLSTIFTLGMALAGVPTGYLLARWSRKAVLQIGIAIFSLGTLLTAYSSGFADMILY
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGVGAIVGPLLGGHLIGIERNWR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCEEEEEECCCC
LPLVVFGLTGFVAMALIAATVSKRMTEKASAIATHIDTRGATTMWNRNTALLTVMSIIGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
LCIYGYLGMYPTFLREHLHYTPSDTGRVMSIFGCGVFASIFGGWLGDRFHPKLVLSLSFA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
GTGLLGFLLFSGPTGMLVQSVLSFVWGLVVSGVLYVNLAGYHIKSVRSSLTNRATGVFVT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TLYGAGAFAGYIIGGIAARFGWSTAGFAQITLLSVFGIVLTVLLRTDRMSLPVRKP
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSSTSAGPLTGDVRSDAPVTALEIGMFLVLLASYALNAMDRQIFPLIAADVRREFGFGL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADTGLLSTIFTLGMALAGVPTGYLLARWSRKAVLQIGIAIFSLGTLLTAYSSGFADMILY
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RAATGIGEAMQLTVVIAIAASYFARFRATAVGAINFSFGVGAIVGPLLGGHLIGIERNWR
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCEEEEEECCCC
LPLVVFGLTGFVAMALIAATVSKRMTEKASAIATHIDTRGATTMWNRNTALLTVMSIIGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHH
LCIYGYLGMYPTFLREHLHYTPSDTGRVMSIFGCGVFASIFGGWLGDRFHPKLVLSLSFA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
GTGLLGFLLFSGPTGMLVQSVLSFVWGLVVSGVLYVNLAGYHIKSVRSSLTNRATGVFVT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TLYGAGAFAGYIIGGIAARFGWSTAGFAQITLLSVFGIVLTVLLRTDRMSLPVRKP
HHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA