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The map label for this gene is ycgM [C]

Identifier: 116694380

GI number: 116694380

Start: 487143

End: 487856

Strand: Direct

Name: ycgM [C]

Synonym: H16_B0428

Alternate gene names: 116694380

Gene position: 487143-487856 (Clockwise)

Preceding gene: 116694378

Following gene: 116694381

Centisome position: 16.73

GC content: 60.78

Gene sequence:

>714_bases
ATGCCTAGAGCCAGTGCGGACAGCGTCGTGCAATCGACCAAGGTCCTGAGCGTTACCCCCGCCTTCATTGATATCGTTGG
CAGCGATCAACGCTTCCCGGTGCGGCGCGTCTATTGCGTGGGGCGCAACTACCTTGCCCATATCCGGGAAATGGGGGAGG
GTGACGAACGCGACCCCCCATTCTTCTTCCAGAAGCCGGCCGATGCCATTGTGACCGATGGCCGCGTCCCCTATCCGACG
TTTACTGATGACTTTCAGTTCGAGTTTGAACTCGTCGTTGCCATCGGCCGTGAAGCGACGGAAGTGCCGCCGGACACTGC
ACTGGATCATGTCTTTGGCTATGCCGCAGGGCTTGACATGACGCGGCGGGACCGCCAACGCGAATGCAACAAGCGCGGCC
TGCCGTGGGAGCTGGGCAAGTCATTCGACCATTCGGCGCCATGCGGTCCCATCCATCCCGTGGCGAAGGTCGGCCATCTC
CGTTCGGGCGCACTGAGCCTGGCGGTAAACGGTGACGTACGACAGCACTCGGTCCTGGAGAAGATGATCTGGAACGTCCA
TGAAATCGTCAGCGAGCTGTCCAGGCAGTATCGCCTGCTTCCTGGCGACCTGATCTTTACCGGCACGCCAGAAGGCGTTG
GTCCGGTGCAGCGCGGTGACAGGTTGATCGGCCGTATTGAAGGACTCGACCCCTTGCAGGTCGAGATCGTCTGA

Upstream 100 bases:

>100_bases
GGATTGCGCATCTTTTCGCAAGCCTGTGCGTTGAGGCCGAACGACCGCGTCTCTAAACTCTAGCCACTCCGTTCAATAAT
CTTACACAGAGACAATCCTT

Downstream 100 bases:

>100_bases
GTCCCGGGTCAAAGGAAACACGCCATGAAACCACTCGAACGCATCTCATTTTCGGCCATTTCCGAGCGTCCCGCCCTGAC
GCTGCCGGCTGGCAAGCGCC

Product: putative fumarylpyruvate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MPRASADSVVQSTKVLSVTPAFIDIVGSDQRFPVRRVYCVGRNYLAHIREMGEGDERDPPFFFQKPADAIVTDGRVPYPT
FTDDFQFEFELVVAIGREATEVPPDTALDHVFGYAAGLDMTRRDRQRECNKRGLPWELGKSFDHSAPCGPIHPVAKVGHL
RSGALSLAVNGDVRQHSVLEKMIWNVHEIVSELSRQYRLLPGDLIFTGTPEGVGPVQRGDRLIGRIEGLDPLQVEIV

Sequences:

>Translated_237_residues
MPRASADSVVQSTKVLSVTPAFIDIVGSDQRFPVRRVYCVGRNYLAHIREMGEGDERDPPFFFQKPADAIVTDGRVPYPT
FTDDFQFEFELVVAIGREATEVPPDTALDHVFGYAAGLDMTRRDRQRECNKRGLPWELGKSFDHSAPCGPIHPVAKVGHL
RSGALSLAVNGDVRQHSVLEKMIWNVHEIVSELSRQYRLLPGDLIFTGTPEGVGPVQRGDRLIGRIEGLDPLQVEIV
>Mature_236_residues
PRASADSVVQSTKVLSVTPAFIDIVGSDQRFPVRRVYCVGRNYLAHIREMGEGDERDPPFFFQKPADAIVTDGRVPYPTF
TDDFQFEFELVVAIGREATEVPPDTALDHVFGYAAGLDMTRRDRQRECNKRGLPWELGKSFDHSAPCGPIHPVAKVGHLR
SGALSLAVNGDVRQHSVLEKMIWNVHEIVSELSRQYRLLPGDLIFTGTPEGVGPVQRGDRLIGRIEGLDPLQVEIV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=203, Percent_Identity=40.3940886699507, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=41.8367346938776, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=41.8367346938776, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI156231349, Length=203, Percent_Identity=33.0049261083744, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI40786394, Length=203, Percent_Identity=33.0049261083744, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787428, Length=200, Percent_Identity=38, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=185, Percent_Identity=34.0540540540541, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324161, Length=221, Percent_Identity=33.4841628959276, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28572127, Length=213, Percent_Identity=34.7417840375587, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571789, Length=178, Percent_Identity=32.5842696629214, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24663695, Length=213, Percent_Identity=26.2910798122066, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 26375; Mature: 26244

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRASADSVVQSTKVLSVTPAFIDIVGSDQRFPVRRVYCVGRNYLAHIREMGEGDERDPP
CCCCCHHHHHHHHHHEEECHHHEEEECCCCCCCHHEEEECCHHHHHHHHHHCCCCCCCCC
FFFQKPADAIVTDGRVPYPTFTDDFQFEFELVVAIGREATEVPPDTALDHVFGYAAGLDM
EEEECCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCH
TRRDRQRECNKRGLPWELGKSFDHSAPCGPIHPVAKVGHLRSGALSLAVNGDVRQHSVLE
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHH
KMIWNVHEIVSELSRQYRLLPGDLIFTGTPEGVGPVQRGDRLIGRIEGLDPLQVEIV
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure 
PRASADSVVQSTKVLSVTPAFIDIVGSDQRFPVRRVYCVGRNYLAHIREMGEGDERDPP
CCCCHHHHHHHHHHEEECHHHEEEECCCCCCCHHEEEECCHHHHHHHHHHCCCCCCCCC
FFFQKPADAIVTDGRVPYPTFTDDFQFEFELVVAIGREATEVPPDTALDHVFGYAAGLDM
EEEECCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCH
TRRDRQRECNKRGLPWELGKSFDHSAPCGPIHPVAKVGHLRSGALSLAVNGDVRQHSVLE
HHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCHHHHHHHH
KMIWNVHEIVSELSRQYRLLPGDLIFTGTPEGVGPVQRGDRLIGRIEGLDPLQVEIV
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]