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The map label for this gene is ucpA [C]

Identifier: 116694347

GI number: 116694347

Start: 450738

End: 451697

Strand: Direct

Name: ucpA [C]

Synonym: H16_B0394

Alternate gene names: 116694347

Gene position: 450738-451697 (Clockwise)

Preceding gene: 116694346

Following gene: 116694348

Centisome position: 15.48

GC content: 65.52

Gene sequence:

>960_bases
ATGGACACACACCTTTCGTTCAACCCGATTTACTGGAGTGTCCAAGACATGAGCCTGCTTGAAGGGAAAGTCATCATCGT
GACCGGCGCCGGCGCCGGCGTGGGCAAGGGGATCGCGCTGGAGGCGGCCCGCCAGGGTGCGCGCGTGATCGTCAACGACA
TCGGCGTCAACATCGACGGCTCGGGCGGCAGCGCCAGCCCCGGCGAACAGGTCGTCGCGGAAATCCGCGCGGCTGGCGGC
GAGGCGGCGGTCAACACCGACAGCGTGGCCGACTGGGGCGCGGCGCAGAAGATCGCCCAGCAGGCCATGGACCTGTATGG
CCGCATCGATGGCGTGGTCAACAACGCCGGCAACCTGCGCGACGTCCTCTTCCACAAGATGAGCGAAGAAGAGTTCGACG
CCGTGATCGCGGTCCACCTCAAGGGCAGCTGGAACGTCTCGCGCTCGGTGGCGCCGCATTTCAAGGCGCAGGAGAGCGGC
GCCTTTGTCCACATGACCTCGACCACCGGCCTGATCGGCAACTTCGGCCAGGCCAACTATGCGGCGGCCAAGCTCGGCAT
CGTCGCGCTGTCGAAGTCCATCGCCATCGACATGCAGAAGTTCAACGTGCGCTCCAACTGCATCGCGCCGTTCGCCTTCA
CGCGCATGGTCGACAGCGTGCCCGCCAATACGCCGGAAGCGCTGGAACGCCGCAAGGTCAACATGCGCCTGGAGGCCGGC
AAGATCGCGCCGTTCACGCTGGCCCTGCTGGCCGACGAAGCGAAGCACGTCAACGCCCAGGTCTTCGGCGTGCGCAACAA
CGAAGTCTTCCTGTTCTCCCAGCCGCGGCCGATCCGCTCGGCCCACAGGAGCGAAGGCTGGACCGTGCAGTCCTGCGTGG
AGCATGCCATCCCGATGCTCAAGAGTTCGTTCGTCCCGTTCGAGCTGTCGCGCGACATCTTCACCTGGGACCCGGTCTGA

Upstream 100 bases:

>100_bases
GCGCGCGGACCTTACGCATGCTTATCCGCGCGCCATAAGCTCCGCTCCTCCCCATGCCACCCGAGTCGGGGAGTACCTGC
CCCGGGCCCGCCGGCCAATC

Downstream 100 bases:

>100_bases
CCGCGGATCACGGCTTCAAAGGAGCAATGCAATGGATTTCGAGCCCGATCTCGGACTGGAGGCGTTCCGCCAGGAAGTAC
GGACTTTCCTGCGCGAGAGC

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDTHLSFNPIYWSVQDMSLLEGKVIIVTGAGAGVGKGIALEAARQGARVIVNDIGVNIDGSGGSASPGEQVVAEIRAAGG
EAAVNTDSVADWGAAQKIAQQAMDLYGRIDGVVNNAGNLRDVLFHKMSEEEFDAVIAVHLKGSWNVSRSVAPHFKAQESG
AFVHMTSTTGLIGNFGQANYAAAKLGIVALSKSIAIDMQKFNVRSNCIAPFAFTRMVDSVPANTPEALERRKVNMRLEAG
KIAPFTLALLADEAKHVNAQVFGVRNNEVFLFSQPRPIRSAHRSEGWTVQSCVEHAIPMLKSSFVPFELSRDIFTWDPV

Sequences:

>Translated_319_residues
MDTHLSFNPIYWSVQDMSLLEGKVIIVTGAGAGVGKGIALEAARQGARVIVNDIGVNIDGSGGSASPGEQVVAEIRAAGG
EAAVNTDSVADWGAAQKIAQQAMDLYGRIDGVVNNAGNLRDVLFHKMSEEEFDAVIAVHLKGSWNVSRSVAPHFKAQESG
AFVHMTSTTGLIGNFGQANYAAAKLGIVALSKSIAIDMQKFNVRSNCIAPFAFTRMVDSVPANTPEALERRKVNMRLEAG
KIAPFTLALLADEAKHVNAQVFGVRNNEVFLFSQPRPIRSAHRSEGWTVQSCVEHAIPMLKSSFVPFELSRDIFTWDPV
>Mature_319_residues
MDTHLSFNPIYWSVQDMSLLEGKVIIVTGAGAGVGKGIALEAARQGARVIVNDIGVNIDGSGGSASPGEQVVAEIRAAGG
EAAVNTDSVADWGAAQKIAQQAMDLYGRIDGVVNNAGNLRDVLFHKMSEEEFDAVIAVHLKGSWNVSRSVAPHFKAQESG
AFVHMTSTTGLIGNFGQANYAAAKLGIVALSKSIAIDMQKFNVRSNCIAPFAFTRMVDSVPANTPEALERRKVNMRLEAG
KIAPFTLALLADEAKHVNAQVFGVRNNEVFLFSQPRPIRSAHRSEGWTVQSCVEHAIPMLKSSFVPFELSRDIFTWDPV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=43.4959349593496, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI15277342, Length=212, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI40254992, Length=200, Percent_Identity=29.5, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=27.1739130434783, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=26.3565891472868, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4758504, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40807363, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=28, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI59889578, Length=166, Percent_Identity=28.3132530120482, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=32.8125, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=30.5220883534137, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=208, Percent_Identity=27.8846153846154, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=30.241935483871, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787526, Length=261, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=215, Percent_Identity=25.1162790697674, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=25.8964143426295, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=215, Percent_Identity=46.9767441860465, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=31.0756972111554, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=268, Percent_Identity=30.5970149253731, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17564282, Length=224, Percent_Identity=27.2321428571429, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567345, Length=239, Percent_Identity=26.3598326359833, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=209, Percent_Identity=27.7511961722488, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=210, Percent_Identity=25.2380952380952, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=223, Percent_Identity=24.6636771300448, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=23.7354085603113, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=42.5, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18859837, Length=200, Percent_Identity=43.5, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=32.6612903225806, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737361, Length=218, Percent_Identity=31.1926605504587, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=27.7551020408163, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=206, Percent_Identity=23.7864077669903, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34249; Mature: 34249

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTHLSFNPIYWSVQDMSLLEGKVIIVTGAGAGVGKGIALEAARQGARVIVNDIGVNIDG
CCCCCCCCCEEEEEECHHHHCCEEEEEECCCCCCCCCEEHHHHHCCCEEEEEECCEEEEC
SGGSASPGEQVVAEIRAAGGEAAVNTDSVADWGAAQKIAQQAMDLYGRIDGVVNNAGNLR
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DVLFHKMSEEEFDAVIAVHLKGSWNVSRSVAPHFKAQESGAFVHMTSTTGLIGNFGQANY
HHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCH
AAAKLGIVALSKSIAIDMQKFNVRSNCIAPFAFTRMVDSVPANTPEALERRKVNMRLEAG
HHHHHHHHEECHHHEEEHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECC
KIAPFTLALLADEAKHVNAQVFGVRNNEVFLFSQPRPIRSAHRSEGWTVQSCVEHAIPML
CCCCEEEEEEHHCCCCCCEEEEEEECCEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHH
KSSFVPFELSRDIFTWDPV
HHCCCCEEECCCEEECCCC
>Mature Secondary Structure
MDTHLSFNPIYWSVQDMSLLEGKVIIVTGAGAGVGKGIALEAARQGARVIVNDIGVNIDG
CCCCCCCCCEEEEEECHHHHCCEEEEEECCCCCCCCCEEHHHHHCCCEEEEEECCEEEEC
SGGSASPGEQVVAEIRAAGGEAAVNTDSVADWGAAQKIAQQAMDLYGRIDGVVNNAGNLR
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
DVLFHKMSEEEFDAVIAVHLKGSWNVSRSVAPHFKAQESGAFVHMTSTTGLIGNFGQANY
HHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCH
AAAKLGIVALSKSIAIDMQKFNVRSNCIAPFAFTRMVDSVPANTPEALERRKVNMRLEAG
HHHHHHHHEECHHHEEEHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCEEEECC
KIAPFTLALLADEAKHVNAQVFGVRNNEVFLFSQPRPIRSAHRSEGWTVQSCVEHAIPML
CCCCEEEEEEHHCCCCCCEEEEEEECCEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHH
KSSFVPFELSRDIFTWDPV
HHCCCCEEECCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]