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The map label for this gene is ybhD [H]

Identifier: 116694290

GI number: 116694290

Start: 377547

End: 378443

Strand: Direct

Name: ybhD [H]

Synonym: H16_B0336

Alternate gene names: 116694290

Gene position: 377547-378443 (Clockwise)

Preceding gene: 116694286

Following gene: 116694292

Centisome position: 12.96

GC content: 59.87

Gene sequence:

>897_bases
ATGAATTTCGATTTGGCGGACTTGCGAGCGTTCCTGGCCGTAGCCGATCTGGGCAGCTTCAAGGCGGCATCCGATGCGAT
GTTCCTGTCGCAGTCGGCACTGTCGCGTCGCGTCGATAAACTGGAAGAAGCGCTTGGCGTCGCGCTGTTCACGCGGACCA
CCCGGAAAGTCGAATTGACTACCCTGGGCCGCATGTTTGTGCACAAGGCGCGAAACGTCATCAACGAGCTGGAAGAGGCC
ATGCTCGGCATCCAGACCGTTGCCGATCGGCTGTCGGGCGAGGTGACGCTTGCATGCGTACCGTCTGCGGTCGGGCATTT
CCTGCCCTCTGTCGTGGGGCCGTATCACGAGCGCTATCCGGGGATACGGATCCGCATCATTGACGAGTCTTCCGGGGATG
TCCTTCTCGCGGTCACGCGCGGCGATGCGGATTTCGGCCTGACCTATATCGGGACGCAGGAGCCTGACATCGATTTCTGC
CCCTTGATTGAAGAGGCGTTCGTTGTCGCCTGTCGCAAGGGGCATCCGCTGGCGACGCGAAGAAGCGTCAAATGGAAAGA
CCTTGAAGGCTTTGACTACATTACGCTCGCGCAAGGCAGCGGCAACCGCTTCCTGATCGACCAGGCCCTTGCGCGGCTGC
CGGTAAGACCGCGATGGTACTGCGAGGTAAATCATGTTCCCGCCTTGGTAAGCCTGGTCCAGGCCGACCTGGGAATCGGT
GTTGTGCCTCGAATGGCTTTGCCGCCGAAGTCCAGCAGTGGTCTGCTTGCGATCCCGCTGACTGACCCAGTGATAACTCG
AACGTTGGGATTGATCTCGCGACGAGGACGCCCGTTGGCGCCGGCCGCTCAGTTTCTCTTTGACATGCTTATCCGAAGAG
GAACAGCGAAACCCTAG

Upstream 100 bases:

>100_bases
TGGTCAGGACAGTGTTTCGTTCCATCCATAGGGCGAATGATCACGCTGACCGGATTCCAGTGTAAAGTGCAAAGATCACA
AGTATTCTTGCGTAAGACAC

Downstream 100 bases:

>100_bases
GCGCGTGGCACGAAGTTACTGCCGTGTCAGTGACCACCGGTGTCAGAGCACCCATGGTCACTCGGGAAGGAAGCGATGAT
CGACCGAGAATGGCCGACCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNFDLADLRAFLAVADLGSFKAASDAMFLSQSALSRRVDKLEEALGVALFTRTTRKVELTTLGRMFVHKARNVINELEEA
MLGIQTVADRLSGEVTLACVPSAVGHFLPSVVGPYHERYPGIRIRIIDESSGDVLLAVTRGDADFGLTYIGTQEPDIDFC
PLIEEAFVVACRKGHPLATRRSVKWKDLEGFDYITLAQGSGNRFLIDQALARLPVRPRWYCEVNHVPALVSLVQADLGIG
VVPRMALPPKSSSGLLAIPLTDPVITRTLGLISRRGRPLAPAAQFLFDMLIRRGTAKP

Sequences:

>Translated_298_residues
MNFDLADLRAFLAVADLGSFKAASDAMFLSQSALSRRVDKLEEALGVALFTRTTRKVELTTLGRMFVHKARNVINELEEA
MLGIQTVADRLSGEVTLACVPSAVGHFLPSVVGPYHERYPGIRIRIIDESSGDVLLAVTRGDADFGLTYIGTQEPDIDFC
PLIEEAFVVACRKGHPLATRRSVKWKDLEGFDYITLAQGSGNRFLIDQALARLPVRPRWYCEVNHVPALVSLVQADLGIG
VVPRMALPPKSSSGLLAIPLTDPVITRTLGLISRRGRPLAPAAQFLFDMLIRRGTAKP
>Mature_298_residues
MNFDLADLRAFLAVADLGSFKAASDAMFLSQSALSRRVDKLEEALGVALFTRTTRKVELTTLGRMFVHKARNVINELEEA
MLGIQTVADRLSGEVTLACVPSAVGHFLPSVVGPYHERYPGIRIRIIDESSGDVLLAVTRGDADFGLTYIGTQEPDIDFC
PLIEEAFVVACRKGHPLATRRSVKWKDLEGFDYITLAQGSGNRFLIDQALARLPVRPRWYCEVNHVPALVSLVQADLGIG
VVPRMALPPKSSSGLLAIPLTDPVITRTLGLISRRGRPLAPAAQFLFDMLIRRGTAKP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=41.0169491525424, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=33.445945945946, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI157672245, Length=279, Percent_Identity=29.0322580645161, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=28.3737024221453, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787601, Length=287, Percent_Identity=28.2229965156794, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788887, Length=254, Percent_Identity=28.740157480315, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789204, Length=268, Percent_Identity=25.7462686567164, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787530, Length=293, Percent_Identity=23.5494880546075, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=28.7671232876712, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790208, Length=294, Percent_Identity=26.1904761904762, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=25.4032258064516, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788706, Length=169, Percent_Identity=28.9940828402367, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787806, Length=288, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=24.5967741935484, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786713, Length=186, Percent_Identity=32.7956989247312, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=27.4285714285714, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1786401, Length=125, Percent_Identity=31.2, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=24.896265560166, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=23.7704918032787, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789173, Length=147, Percent_Identity=31.2925170068027, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786508, Length=189, Percent_Identity=29.1005291005291, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=157, Percent_Identity=28.6624203821656, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790262, Length=268, Percent_Identity=21.2686567164179, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789639, Length=123, Percent_Identity=26.8292682926829, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=250, Percent_Identity=28, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693193, Length=119, Percent_Identity=31.0924369747899, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786448, Length=187, Percent_Identity=28.8770053475936, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32607; Mature: 32607

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDLADLRAFLAVADLGSFKAASDAMFLSQSALSRRVDKLEEALGVALFTRTTRKVELT
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEHH
TLGRMFVHKARNVINELEEAMLGIQTVADRLSGEVTLACVPSAVGHFLPSVVGPYHERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHCC
GIRIRIIDESSGDVLLAVTRGDADFGLTYIGTQEPDIDFCPLIEEAFVVACRKGHPLATR
CEEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
RSVKWKDLEGFDYITLAQGSGNRFLIDQALARLPVRPRWYCEVNHVPALVSLVQADLGIG
CCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCC
VVPRMALPPKSSSGLLAIPLTDPVITRTLGLISRRGRPLAPAAQFLFDMLIRRGTAKP
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFDLADLRAFLAVADLGSFKAASDAMFLSQSALSRRVDKLEEALGVALFTRTTRKVELT
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEHH
TLGRMFVHKARNVINELEEAMLGIQTVADRLSGEVTLACVPSAVGHFLPSVVGPYHERYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHCC
GIRIRIIDESSGDVLLAVTRGDADFGLTYIGTQEPDIDFCPLIEEAFVVACRKGHPLATR
CEEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
RSVKWKDLEGFDYITLAQGSGNRFLIDQALARLPVRPRWYCEVNHVPALVSLVQADLGIG
CCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCC
VVPRMALPPKSSSGLLAIPLTDPVITRTLGLISRRGRPLAPAAQFLFDMLIRRGTAKP
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]