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The map label for this gene is fhaC [H]

Identifier: 116694203

GI number: 116694203

Start: 284116

End: 285843

Strand: Direct

Name: fhaC [H]

Synonym: H16_B0248

Alternate gene names: 116694203

Gene position: 284116-285843 (Clockwise)

Preceding gene: 116694202

Following gene: 116694204

Centisome position: 9.76

GC content: 66.61

Gene sequence:

>1728_bases
ATGCGACTAGATTCTCAGGCGCGTCGCAAGGCGCGCGGCGTCTTCCCGTTTGTCCCGTTCCTGCTGACGTTGCCCTCCCT
GGCCGCCGCCCAGGCCCAACCCTTCTTCCCGCAGGTTACCCCCAACGACGCCATCGAGCGCCGCCAGGAACAACAGCAGG
AGGCCGCGCGCGAACGTGCCATGGCCCGCCCCGATGTGCTGACGCCGGGTCCGGCCGAGCCGGCCCTGGCAGGCCCGCTG
ATCCTCCGCAACGAATCCCCCTGCTTCCCGATCAAGACCGTGCACTGGGAAGACGCCGATGAGTTCGAGTGGTTGCAAGC
CGAGGCCAGCATCCTGCCCGGTCAGTGCGTGGGCGGCCAGGGGCTGGAAGCCATCCAGGACTACTTCTCCGCACGCTTGG
TAGTCCGAGGCTACATGACCACGCGCGTGCTGATTCCTGAGCAAAGCCTCGCCAGCGGTGAACTACGGCTGCGCGTGGTG
GCCGGACACATCACCGGCGTCAAGGCCGAGGGCACGCCCGGTTGGTGGCGAACCGCGCTGCCGACCCGCCCGGGAGGGCT
GGTGAACCAGCGCGACCTGGACCAGGGCATGGAGAACATGCGTCGTCTGCAGGGCCAGGCCGACGCCAGTATCGACCTGG
TACCGGGAGAGAAGCCAGGCGATACCGAGTTGGTCGTCAAGCCCGGCACCGGCAAGCGCTGGCATGCCCTGATCACGGGT
GACAACGCCGGCCTGGACAACACCGGCAAGTACCAGATGGGCGGCACGCTGACGGTGGATTCGCCGTTGTTCCTGTACGA
CAGCCTGACCATTTCCGGCAACACCAATGCCAACCTCGGCAACGGCGCGGCCGGTGCGCGCTCGTCGGCCATCAACTACA
GCATTCCGTTTGGCTACTGGAACGCCTTTTTCAACGCCAACCAGTCGAAATACCACCAGACCGTGGCGGGCTTCGAGGGC
GATATCGCCTACGGCGGGCGCAGCACACAGATCGAGGCGGGCCTGGGCTATGTGCCGTTTCGCAACGCCTCGGGCAAGAC
CAGCCTGTACGGCAAGGTGTTCCGCAAGACCGCCAGCACCACGCTGGACGGCATCGACATCGCCGTGCAGCGTCGGGATT
TCGTCGGTTACGAGGTCGGTGCCTCGCATCGCCAGTACCTTGGCAACACGGTGCTGGATATCGGCGCGGCCTGGCGTGCA
TCCCTGCCCGCGCATTCCAAGACGCCCGGCTTCGTGCTGGGCGATCCGGACTGGGGCGGCAAGTCTGAACTGCTGCTCGC
CAACGCGGGCCTGATGGTGCCGTTCCAGGTCGCCGGGCAGCGCCTGCGCTACCAGGGCAACCTGCGCATGCAGTACGCGC
ACACCCGCATCCTGCCCTCCGACTATTTCGTTATCGGCAACCGCTACTCGGTGCGCGGCTTCGATGAGCAGCTGACGCTG
GCCGCGGAGAACGGCGTGACCTGGCGCAACGACGTGGCCTGGCAACTTGGCAATACTGGACAAGAAGCCTTTGTCGGCTT
CGACGCCGGCCACGTCAGCGGCCCGTCTGCGGCATTCCTGGTCGGCCAGACCCTGATGGGCGCGGTGATCGGCGCGCGCG
GGCGCTGGGCCATGGGCGGCTTTGCCGCGCTGACCTATGAGGTAACGCTCGGCTGGCCGGTCAGGAAGCCCGAGTTCTTC
CGCACGCGCCAGCCCAATCTCGCTGCGCAGATCGGGGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
CGATCTTTGGCCTTGGTTCCCTTCTCGTTGGAAGAGAGAGTTCACCGGTGCACGGCGAAGTCTCCGCGAGCGATACGCAA
GAAGAATAGGTACATCTCCA

Downstream 100 bases:

>100_bases
TCCGCCCGAACGGTGCGGAGTATCGACTTGCTGCTGTGACAGAGCATGAATGTAGTGTTGACCCAACTGAAGGAGAAGAT
CGCATGAACAAAGTGACGGC

Product: filamentous hemagglutinin activation/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MRLDSQARRKARGVFPFVPFLLTLPSLAAAQAQPFFPQVTPNDAIERRQEQQQEAARERAMARPDVLTPGPAEPALAGPL
ILRNESPCFPIKTVHWEDADEFEWLQAEASILPGQCVGGQGLEAIQDYFSARLVVRGYMTTRVLIPEQSLASGELRLRVV
AGHITGVKAEGTPGWWRTALPTRPGGLVNQRDLDQGMENMRRLQGQADASIDLVPGEKPGDTELVVKPGTGKRWHALITG
DNAGLDNTGKYQMGGTLTVDSPLFLYDSLTISGNTNANLGNGAAGARSSAINYSIPFGYWNAFFNANQSKYHQTVAGFEG
DIAYGGRSTQIEAGLGYVPFRNASGKTSLYGKVFRKTASTTLDGIDIAVQRRDFVGYEVGASHRQYLGNTVLDIGAAWRA
SLPAHSKTPGFVLGDPDWGGKSELLLANAGLMVPFQVAGQRLRYQGNLRMQYAHTRILPSDYFVIGNRYSVRGFDEQLTL
AAENGVTWRNDVAWQLGNTGQEAFVGFDAGHVSGPSAAFLVGQTLMGAVIGARGRWAMGGFAALTYEVTLGWPVRKPEFF
RTRQPNLAAQIGVEF

Sequences:

>Translated_575_residues
MRLDSQARRKARGVFPFVPFLLTLPSLAAAQAQPFFPQVTPNDAIERRQEQQQEAARERAMARPDVLTPGPAEPALAGPL
ILRNESPCFPIKTVHWEDADEFEWLQAEASILPGQCVGGQGLEAIQDYFSARLVVRGYMTTRVLIPEQSLASGELRLRVV
AGHITGVKAEGTPGWWRTALPTRPGGLVNQRDLDQGMENMRRLQGQADASIDLVPGEKPGDTELVVKPGTGKRWHALITG
DNAGLDNTGKYQMGGTLTVDSPLFLYDSLTISGNTNANLGNGAAGARSSAINYSIPFGYWNAFFNANQSKYHQTVAGFEG
DIAYGGRSTQIEAGLGYVPFRNASGKTSLYGKVFRKTASTTLDGIDIAVQRRDFVGYEVGASHRQYLGNTVLDIGAAWRA
SLPAHSKTPGFVLGDPDWGGKSELLLANAGLMVPFQVAGQRLRYQGNLRMQYAHTRILPSDYFVIGNRYSVRGFDEQLTL
AAENGVTWRNDVAWQLGNTGQEAFVGFDAGHVSGPSAAFLVGQTLMGAVIGARGRWAMGGFAALTYEVTLGWPVRKPEFF
RTRQPNLAAQIGVEF
>Mature_575_residues
MRLDSQARRKARGVFPFVPFLLTLPSLAAAQAQPFFPQVTPNDAIERRQEQQQEAARERAMARPDVLTPGPAEPALAGPL
ILRNESPCFPIKTVHWEDADEFEWLQAEASILPGQCVGGQGLEAIQDYFSARLVVRGYMTTRVLIPEQSLASGELRLRVV
AGHITGVKAEGTPGWWRTALPTRPGGLVNQRDLDQGMENMRRLQGQADASIDLVPGEKPGDTELVVKPGTGKRWHALITG
DNAGLDNTGKYQMGGTLTVDSPLFLYDSLTISGNTNANLGNGAAGARSSAINYSIPFGYWNAFFNANQSKYHQTVAGFEG
DIAYGGRSTQIEAGLGYVPFRNASGKTSLYGKVFRKTASTTLDGIDIAVQRRDFVGYEVGASHRQYLGNTVLDIGAAWRA
SLPAHSKTPGFVLGDPDWGGKSELLLANAGLMVPFQVAGQRLRYQGNLRMQYAHTRILPSDYFVIGNRYSVRGFDEQLTL
AAENGVTWRNDVAWQLGNTGQEAFVGFDAGHVSGPSAAFLVGQTLMGAVIGARGRWAMGGFAALTYEVTLGWPVRKPEFF
RTRQPNLAAQIGVEF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62467; Mature: 62467

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDSQARRKARGVFPFVPFLLTLPSLAAAQAQPFFPQVTPNDAIERRQEQQQEAARERA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MARPDVLTPGPAEPALAGPLILRNESPCFPIKTVHWEDADEFEWLQAEASILPGQCVGGQ
HCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
GLEAIQDYFSARLVVRGYMTTRVLIPEQSLASGELRLRVVAGHITGVKAEGTPGWWRTAL
CHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCEEEEEEEEEEEEEECCCCCCCEECCC
PTRPGGLVNQRDLDQGMENMRRLQGQADASIDLVPGEKPGDTELVVKPGTGKRWHALITG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEEEC
DNAGLDNTGKYQMGGTLTVDSPLFLYDSLTISGNTNANLGNGAAGARSSAINYSIPFGYW
CCCCCCCCCCEECCCEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHH
NAFFNANQSKYHQTVAGFEGDIAYGGRSTQIEAGLGYVPFRNASGKTSLYGKVFRKTAST
HHHHCCCHHHHHHHHCCCCCCEEECCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHC
TLDGIDIAVQRRDFVGYEVGASHRQYLGNTVLDIGAAWRASLPAHSKTPGFVLGDPDWGG
CCCCEEEEEEECCCCCEECCCCHHHHHCCHHEECCCHHHCCCCCCCCCCCEEECCCCCCC
KSELLLANAGLMVPFQVAGQRLRYQGNLRMQYAHTRILPSDYFVIGNRYSVRGFDEQLTL
CCCEEEECCCCEEEHHHCCCEEEEECCEEEEEEEEEECCCCEEEECCEEEECCCCCEEEE
AAENGVTWRNDVAWQLGNTGQEAFVGFDAGHVSGPSAAFLVGQTLMGAVIGARGRWAMGG
EECCCCEECCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
FAALTYEVTLGWPVRKPEFFRTRQPNLAAQIGVEF
EEEEEEEEEECCCCCCCHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MRLDSQARRKARGVFPFVPFLLTLPSLAAAQAQPFFPQVTPNDAIERRQEQQQEAARERA
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MARPDVLTPGPAEPALAGPLILRNESPCFPIKTVHWEDADEFEWLQAEASILPGQCVGGQ
HCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
GLEAIQDYFSARLVVRGYMTTRVLIPEQSLASGELRLRVVAGHITGVKAEGTPGWWRTAL
CHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCEEEEEEEEEEEEEECCCCCCCEECCC
PTRPGGLVNQRDLDQGMENMRRLQGQADASIDLVPGEKPGDTELVVKPGTGKRWHALITG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCEEEEEEEC
DNAGLDNTGKYQMGGTLTVDSPLFLYDSLTISGNTNANLGNGAAGARSSAINYSIPFGYW
CCCCCCCCCCEECCCEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHH
NAFFNANQSKYHQTVAGFEGDIAYGGRSTQIEAGLGYVPFRNASGKTSLYGKVFRKTAST
HHHHCCCHHHHHHHHCCCCCCEEECCCCCEEECCCCEEEECCCCCCCHHHHHHHHHHHHC
TLDGIDIAVQRRDFVGYEVGASHRQYLGNTVLDIGAAWRASLPAHSKTPGFVLGDPDWGG
CCCCEEEEEEECCCCCEECCCCHHHHHCCHHEECCCHHHCCCCCCCCCCCEEECCCCCCC
KSELLLANAGLMVPFQVAGQRLRYQGNLRMQYAHTRILPSDYFVIGNRYSVRGFDEQLTL
CCCEEEECCCCEEEHHHCCCEEEEECCEEEEEEEEEECCCCEEEECCEEEECCCCCEEEE
AAENGVTWRNDVAWQLGNTGQEAFVGFDAGHVSGPSAAFLVGQTLMGAVIGARGRWAMGG
EECCCCEECCCEEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
FAALTYEVTLGWPVRKPEFFRTRQPNLAAQIGVEF
EEEEEEEEEECCCCCCCHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]