Click here to switch to the map view.

The map label for this gene is cheA1 [H]

Identifier: 116694194

GI number: 116694194

Start: 267159

End: 269159

Strand: Direct

Name: cheA1 [H]

Synonym: H16_B0239

Alternate gene names: 116694194

Gene position: 267159-269159 (Clockwise)

Preceding gene: 116694193

Following gene: 116694195

Centisome position: 9.17

GC content: 66.17

Gene sequence:

>2001_bases
ATGTCTGTCGATATCGATATCACACAGTTTTACCAGACCTTCTTCGAGGAAGCGGAAGAACTGCTCGTCGAAATGGAGCA
GCTGCTGCTCGGCCTGGACATTGAGTCGCCCGATCCCGAGCATCTGAACGCGATCTTCCGGGCGGCGCATTCCATCAAGG
GCGGGGCTGCCACCTTCGGCTTCGCGGCGCTGACCGAGACCACCCATATTTTCGAGAACCTGCTGGACCGCACGCGCCGG
CAGGAACTGGCGTTGACCAGGACCATCATCGACACCTTTCTGGAAACCAAGGACGTGTTGCAAGACCAGCTCAACGCCTA
CCGCAACGGCACCGAACCCGATCCGGAAACGCTGGCGCGCATCTGCGCCGTGCTGCAACAGCTGGCGCAGGAAGCCGCCG
GCCATGCCGGCGCAGCTGCCCCGGCGCCCGTACCTGTTGCCGCAACGCCCCCCGCTGCTGCTCCTGCGGGCGGCGGGCTC
AAGATCCGCCTGATCCGGGTTTCCGCCTCCGACCAGGCGCTGCTGCGCGAGGAACTGGCCAACCTGGGCGAGATCACCGG
CCAGCAAGAGGTGAATGGCGAACTGGTGGTGTGGCTCAACACCCAGTGCAGCGCCGACGACATCATCGCGGTGTGCTGCT
TCGTGATCGACCTGGACCAGATCGTGATCGAAGCCGAAGCCCCTGCTGCTGCTCCCGCGGTGGTCGAGGCCCCTGTCCCG
GCGCCCGTCCCGGTCGCCACGGCCCCCGCCCCCGCAGCGGCGGCGCCCGCCGCCGCGCGCGAGAAGGCCAAGCCGCAGGC
GAGCGCCGCGCACGGCGAAGGCTCGATCCGCGTGCCGACCGAAAAGGTCGACCAGATCATCAACCTGGTGGGCGAGCTGG
TGATCACGCAGTCGATGCTGGCGCAGACCGCCTCGGCGCTGGACCCGGTGCTGTTCGACCGCCTGTTCTCCGGCATGGGC
CAGCTCGAGCGCAATGCGCGCGACCTGCAGGAAGCGGTGATGTCGATCCGCATGATGCCGATGGACTATGTGTTCTCGCG
CTTCCCGCGGCTGGTGCGCGACCTGGCCAGCAAGCTCGGCAAGCAGATCGACCTGGTCACCTTCGGCAAGGCCACCGAAC
TGGACAAGAGCCTGATCGAACGCATCATCGATCCGCTCACGCACCTGGTGCGCAACAGCCTGGACCACGGCATCGAAACC
CCTGACAAGCGCGTGGCCGCCGGCAAGGACGCGACCGGCCAGCTGATCCTGTCCGCGCAGCACCATGGCGGCAATATCGT
CATTGAAGTCAGCGACGACGGCGGCGGCCTGAACCGCGAACGCATCCTGGCCAAGGCCATCCAGAACGGCCTGCCGGTGT
CGGAGAACATCACCGACGAGGAAGTCTGGCAGCTGATCTTCGCGCCGGGTTTCTCCACTGCCGAGGTCGTCACCGACGTG
TCGGGCCGCGGCGTTGGCATGGACGTGGTCAAGCGCAATATCCAGGAGATGGGCGGCCACGTCCAGATCAGCTCGCGCCC
GGGCCTGGGCACCACCATCCGCATCGTGCTGCCGCTGACGCTGGCGATCCTGGACGGCATGTCGGTCAAGGTGGGCGAAG
AGACCTTCATCCTGCCGCTGAACTGCGTGATGGAGTCGCTGCAGCCCAAGGCCGAGGATGTCCACACCGCCGCCAACTCC
GATCGCGTCATGCACGTGCGCGGCGAATACCTGCCGCTGCTGGAAATGCACCGCGTCTTCAACGTCGCCGACGCGCTGCA
AGAGCCGACGCATGGCATTGCCGTGATCCTGCAGGCCGAAGGCAAGCGCTTTGCGCTGCTGGTGGACCAGCTGATCGGCC
AGCACCAGGTGGTGCTGAAGAACCTGGAAACCAACTATCGCAAGGTGCCGTGCATCTCGGCGGCGACCATCCTTGGCGAC
GGCAGCGTGGCGCTGATCGTCGATGTCGGCGCGCTGCAGCGCACCGGCGTGCGCCGGCAGGAACCGGCGCTGGCGCAGTA
A

Upstream 100 bases:

>100_bases
GCAGCGGCCTCAGCGCCCGCGGCTGCGCCCACGGGCAGCAAACCATGACGCGCGGCCGTTGCGGCAGCGCCAGTGCAGTA
ACCAAGTGACTCAGGACGCC

Downstream 100 bases:

>100_bases
CCGACCAAACACAGGAGAACTAGACATCATGGCCGGCATCGGACACATCGATACCCCCGGAAGCGACGCTTCGGGCCAGG
AGTTCCTGGTCTTCACGCTG

Product: chemotaxis protein histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEHLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRR
QELALTRTIIDTFLETKDVLQDQLNAYRNGTEPDPETLARICAVLQQLAQEAAGHAGAAAPAPVPVAATPPAAAPAGGGL
KIRLIRVSASDQALLREELANLGEITGQQEVNGELVVWLNTQCSADDIIAVCCFVIDLDQIVIEAEAPAAAPAVVEAPVP
APVPVATAPAPAAAAPAAAREKAKPQASAAHGEGSIRVPTEKVDQIINLVGELVITQSMLAQTASALDPVLFDRLFSGMG
QLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIET
PDKRVAAGKDATGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENITDEEVWQLIFAPGFSTAEVVTDV
SGRGVGMDVVKRNIQEMGGHVQISSRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKAEDVHTAANS
DRVMHVRGEYLPLLEMHRVFNVADALQEPTHGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGD
GSVALIVDVGALQRTGVRRQEPALAQ

Sequences:

>Translated_666_residues
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEHLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRR
QELALTRTIIDTFLETKDVLQDQLNAYRNGTEPDPETLARICAVLQQLAQEAAGHAGAAAPAPVPVAATPPAAAPAGGGL
KIRLIRVSASDQALLREELANLGEITGQQEVNGELVVWLNTQCSADDIIAVCCFVIDLDQIVIEAEAPAAAPAVVEAPVP
APVPVATAPAPAAAAPAAAREKAKPQASAAHGEGSIRVPTEKVDQIINLVGELVITQSMLAQTASALDPVLFDRLFSGMG
QLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIET
PDKRVAAGKDATGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENITDEEVWQLIFAPGFSTAEVVTDV
SGRGVGMDVVKRNIQEMGGHVQISSRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKAEDVHTAANS
DRVMHVRGEYLPLLEMHRVFNVADALQEPTHGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGD
GSVALIVDVGALQRTGVRRQEPALAQ
>Mature_665_residues
SVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEHLNAIFRAAHSIKGGAATFGFAALTETTHIFENLLDRTRRQ
ELALTRTIIDTFLETKDVLQDQLNAYRNGTEPDPETLARICAVLQQLAQEAAGHAGAAAPAPVPVAATPPAAAPAGGGLK
IRLIRVSASDQALLREELANLGEITGQQEVNGELVVWLNTQCSADDIIAVCCFVIDLDQIVIEAEAPAAAPAVVEAPVPA
PVPVATAPAPAAAAPAAAREKAKPQASAAHGEGSIRVPTEKVDQIINLVGELVITQSMLAQTASALDPVLFDRLFSGMGQ
LERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLGKQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIETP
DKRVAAGKDATGQLILSAQHHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENITDEEVWQLIFAPGFSTAEVVTDVS
GRGVGMDVVKRNIQEMGGHVQISSRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPLNCVMESLQPKAEDVHTAANSD
RVMHVRGEYLPLLEMHRVFNVADALQEPTHGIAVILQAEGKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDG
SVALIVDVGALQRTGVRRQEPALAQ

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=653, Percent_Identity=62.7871362940276, Blast_Score=783, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71528; Mature: 71397

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEHLNAIFRAAHSIKGGAATFG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FAALTETTHIFENLLDRTRRQELALTRTIIDTFLETKDVLQDQLNAYRNGTEPDPETLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEAAGHAGAAAPAPVPVAATPPAAAPAGGGLKIRLIRVSASDQALLREELA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
NLGEITGQQEVNGELVVWLNTQCSADDIIAVCCFVIDLDQIVIEAEAPAAAPAVVEAPVP
HHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCCC
APVPVATAPAPAAAAPAAAREKAKPQASAAHGEGSIRVPTEKVDQIINLVGELVITQSML
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
AQTASALDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIETPDKRVAAGKDATGQLILSAQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEEEE
HHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENITDEEVWQLIFAPGFSTAEVVTDV
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCC
SGRGVGMDVVKRNIQEMGGHVQISSRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPL
CCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEH
NCVMESLQPKAEDVHTAANSDRVMHVRGEYLPLLEMHRVFNVADALQEPTHGIAVILQAE
HHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECC
GKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQRTGVRRQ
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHHHCCCCCC
EPALAQ
CCCCCC
>Mature Secondary Structure 
SVDIDITQFYQTFFEEAEELLVEMEQLLLGLDIESPDPEHLNAIFRAAHSIKGGAATFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHH
FAALTETTHIFENLLDRTRRQELALTRTIIDTFLETKDVLQDQLNAYRNGTEPDPETLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
ICAVLQQLAQEAAGHAGAAAPAPVPVAATPPAAAPAGGGLKIRLIRVSASDQALLREELA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
NLGEITGQQEVNGELVVWLNTQCSADDIIAVCCFVIDLDQIVIEAEAPAAAPAVVEAPVP
HHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEECCCC
APVPVATAPAPAAAAPAAAREKAKPQASAAHGEGSIRVPTEKVDQIINLVGELVITQSML
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
AQTASALDPVLFDRLFSGMGQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLASKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
KQIDLVTFGKATELDKSLIERIIDPLTHLVRNSLDHGIETPDKRVAAGKDATGQLILSAQ
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCEEEEEEE
HHGGNIVIEVSDDGGGLNRERILAKAIQNGLPVSENITDEEVWQLIFAPGFSTAEVVTDV
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCC
SGRGVGMDVVKRNIQEMGGHVQISSRPGLGTTIRIVLPLTLAILDGMSVKVGEETFILPL
CCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEH
NCVMESLQPKAEDVHTAANSDRVMHVRGEYLPLLEMHRVFNVADALQEPTHGIAVILQAE
HHHHHHCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECC
GKRFALLVDQLIGQHQVVLKNLETNYRKVPCISAATILGDGSVALIVDVGALQRTGVRRQ
CCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCEEEEEECCHHHHCCCCCC
EPALAQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]