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The map label for this gene is aer [H]

Identifier: 116694187

GI number: 116694187

Start: 259335

End: 260984

Strand: Direct

Name: aer [H]

Synonym: H16_B0232

Alternate gene names: 116694187

Gene position: 259335-260984 (Clockwise)

Preceding gene: 116694186

Following gene: 116694188

Centisome position: 8.9

GC content: 69.94

Gene sequence:

>1650_bases
ATGCGAAACAACCAACCCGTTACGCAGCGCGAATACAAGCTCTCCCCATCGGACTACCTGATCTCGCGCACGGACCTCAA
AGGCCGGATCACCTTTGCCAACCGCACCTTTATCGAGGCAAGCGGCTTTGCGGCCGAGGAGCTGCTCGGTGCGGCGCACA
ACCTGGTGCGCCATCCCGACATGCCGCCGGAAGCGTTTGCCGACCTGTGGCAGGACCTGCAGGCCGGCCGCACCTGGATG
GGCGTGGTCAAGAACCGCCGCAAGAACGGCGACTTTTACTGGGTCAACGCGACCGTGACGCCCACGCGCGTCGATGGCCG
CGTGGTCGGCTACACCTCGGTGCGCTCGATGGCGACGCGCGAGCAGGTGGAAGCCGCCGGCGCTGCCTATGCACGATTCC
GGACCGGCCGCGCGGACGGGCTGGCGATCCGCCACGGCGCCGTGGTCCGCACCGGGCTGCGCGGCCTGGTGCAGGGTCTG
CTGCACCTGAACCTGAAGCGCCGCATCCTGTGGGCGCAGGCCGGCGGGATGGTGTGGTTCCTGGCCGCACTGGTTGCGGT
GGAAGCCCTGGGCGGCGCAGGCGTGGCCGCGGTGCGCCCGTGGCTGTGGGGCGGCTTTGCGCTGGCGCTGGCATCGTCGT
TCGCGGCAGGCACCATGCTGCTGGCGCGCGTGCACCGTCCGGTGCGCCACATGCTGGACTTTGCGCTGCGCATGGGCGCG
GGTGACCTGACCACGCGCTTCGAGCACCGCAGCGCCGACGAGATCGGCGCGCTGGCGCAGGCCATGCAGACCATGCAGCG
CAGCCTGCAGTCGGTGGTGCACGAGATCCAGGAAGGCATGGCCAGCATCTCCACGGCAACGCGCCAGGTGGCCGCGGGCA
ACAATGACCTGTCGCAACGCACCGAGCAGCAGGCGGCAGCCCTGGAGCAGACGGCGTCGAGCATGGAAGAGCTGACCAGC
ACGGTGCGCCAGAACGCGGACAACGCGCGCCAGGCCAGCGGGCTGGCGGCGAACGCGTCGGAGACAGCGCTGCGCGGCGG
CGAAGTGGTGGGCCGGGTGGTGCAGACCATGGACGAGATCAACGATGCCTCGAAGAAGATCGTCGACATCATCGGCGTGA
TCGAAGGCATCGCCTTCCAGACCAACATCCTGGCGCTGAACGCGGCGGTGGAAGCGGCGCGCGCCGGCGAGCAGGGCCGC
GGCTTCGCGGTGGTGGCGGGCGAGGTGCGCAGCCTGGCGCAGCGTAGCGCCAACGCGGCCAAGGAGATCAAGGGGCTGAT
CGGCGATACGGTGGAGCGCGTGGACAACGGCTCGGCGCTGGTGGGCCAGGCGGGCAAGACCATGGAAGAGATCGTGCAGG
CGGTCAAGCGCGTGACCGACATCATGGGCGAGATCAGCGCGGCGTCGGCCGAGCAGAGCGCGGGCATCGAGCAGGTCAAC
CAGGCCGTGGCGCAGATGGACGAGGGCACGCAGCAGAACGCGGCGCTGGTGGAAGAAGCCGCCGCCGCCGCCGGCTCGCT
CGAAGAGCAGGCCATGCGCCTGCGCGACGCCATCGCCACGTTCCGCGTCAGCATGCAGGCCGAGGTGCGTCCGCAGCGCC
TGCCGGCCCATGCGCGTGCCGATGCGGCCCAGTCACTGGCACAGGCCTAG

Upstream 100 bases:

>100_bases
GCGGCAGCGCCAACGTTGTCCGGCCGGCGCCCCGCCTGCCGGACCGAACCCGCCCGGGGTGCAGCAACTTGCCGCGCCCG
GGCCTGCAGTACTGTCATAG

Downstream 100 bases:

>100_bases
TCCGAATCAAAGACGAGGCAGGCGCGGAGCACCGGCCTGCATGCGTACAAAACGGGTGCGGCACGCCGCGCCCGAGGCTT
CAGTTACAAGGGGGAGTTGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRNNQPVTQREYKLSPSDYLISRTDLKGRITFANRTFIEASGFAAEELLGAAHNLVRHPDMPPEAFADLWQDLQAGRTWM
GVVKNRRKNGDFYWVNATVTPTRVDGRVVGYTSVRSMATREQVEAAGAAYARFRTGRADGLAIRHGAVVRTGLRGLVQGL
LHLNLKRRILWAQAGGMVWFLAALVAVEALGGAGVAAVRPWLWGGFALALASSFAAGTMLLARVHRPVRHMLDFALRMGA
GDLTTRFEHRSADEIGALAQAMQTMQRSLQSVVHEIQEGMASISTATRQVAAGNNDLSQRTEQQAAALEQTASSMEELTS
TVRQNADNARQASGLAANASETALRGGEVVGRVVQTMDEINDASKKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGDTVERVDNGSALVGQAGKTMEEIVQAVKRVTDIMGEISAASAEQSAGIEQVN
QAVAQMDEGTQQNAALVEEAAAAAGSLEEQAMRLRDAIATFRVSMQAEVRPQRLPAHARADAAQSLAQA

Sequences:

>Translated_549_residues
MRNNQPVTQREYKLSPSDYLISRTDLKGRITFANRTFIEASGFAAEELLGAAHNLVRHPDMPPEAFADLWQDLQAGRTWM
GVVKNRRKNGDFYWVNATVTPTRVDGRVVGYTSVRSMATREQVEAAGAAYARFRTGRADGLAIRHGAVVRTGLRGLVQGL
LHLNLKRRILWAQAGGMVWFLAALVAVEALGGAGVAAVRPWLWGGFALALASSFAAGTMLLARVHRPVRHMLDFALRMGA
GDLTTRFEHRSADEIGALAQAMQTMQRSLQSVVHEIQEGMASISTATRQVAAGNNDLSQRTEQQAAALEQTASSMEELTS
TVRQNADNARQASGLAANASETALRGGEVVGRVVQTMDEINDASKKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGDTVERVDNGSALVGQAGKTMEEIVQAVKRVTDIMGEISAASAEQSAGIEQVN
QAVAQMDEGTQQNAALVEEAAAAAGSLEEQAMRLRDAIATFRVSMQAEVRPQRLPAHARADAAQSLAQA
>Mature_549_residues
MRNNQPVTQREYKLSPSDYLISRTDLKGRITFANRTFIEASGFAAEELLGAAHNLVRHPDMPPEAFADLWQDLQAGRTWM
GVVKNRRKNGDFYWVNATVTPTRVDGRVVGYTSVRSMATREQVEAAGAAYARFRTGRADGLAIRHGAVVRTGLRGLVQGL
LHLNLKRRILWAQAGGMVWFLAALVAVEALGGAGVAAVRPWLWGGFALALASSFAAGTMLLARVHRPVRHMLDFALRMGA
GDLTTRFEHRSADEIGALAQAMQTMQRSLQSVVHEIQEGMASISTATRQVAAGNNDLSQRTEQQAAALEQTASSMEELTS
TVRQNADNARQASGLAANASETALRGGEVVGRVVQTMDEINDASKKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRSLAQRSANAAKEIKGLIGDTVERVDNGSALVGQAGKTMEEIVQAVKRVTDIMGEISAASAEQSAGIEQVN
QAVAQMDEGTQQNAALVEEAAAAAGSLEEQAMRLRDAIATFRVSMQAEVRPQRLPAHARADAAQSLAQA

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=528, Percent_Identity=38.6363636363636, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1788195, Length=330, Percent_Identity=60.3030303030303, Blast_Score=328, Evalue=6e-91,
Organism=Escherichia coli, GI2367378, Length=327, Percent_Identity=60.5504587155963, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=56.4564564564565, Blast_Score=321, Evalue=9e-89,
Organism=Escherichia coli, GI1788194, Length=303, Percent_Identity=57.4257425742574, Blast_Score=301, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 58683; Mature: 58683

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNQPVTQREYKLSPSDYLISRTDLKGRITFANRTFIEASGFAAEELLGAAHNLVRHPD
CCCCCCCCCHHCCCCCCHHEEEECCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCC
MPPEAFADLWQDLQAGRTWMGVVKNRRKNGDFYWVNATVTPTRVDGRVVGYTSVRSMATR
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCEECCCEEEEHHHHHHHHHH
EQVEAAGAAYARFRTGRADGLAIRHGAVVRTGLRGLVQGLLHLNLKRRILWAQAGGMVWF
HHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LAALVAVEALGGAGVAAVRPWLWGGFALALASSFAAGTMLLARVHRPVRHMLDFALRMGA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDLTTRFEHRSADEIGALAQAMQTMQRSLQSVVHEIQEGMASISTATRQVAAGNNDLSQR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TEQQAAALEQTASSMEELTSTVRQNADNARQASGLAANASETALRGGEVVGRVVQTMDEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NDASKKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHH
KEIKGLIGDTVERVDNGSALVGQAGKTMEEIVQAVKRVTDIMGEISAASAEQSAGIEQVN
HHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHH
QAVAQMDEGTQQNAALVEEAAAAAGSLEEQAMRLRDAIATFRVSMQAEVRPQRLPAHARA
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DAAQSLAQA
HHHHHHHCC
>Mature Secondary Structure
MRNNQPVTQREYKLSPSDYLISRTDLKGRITFANRTFIEASGFAAEELLGAAHNLVRHPD
CCCCCCCCCHHCCCCCCHHEEEECCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCC
MPPEAFADLWQDLQAGRTWMGVVKNRRKNGDFYWVNATVTPTRVDGRVVGYTSVRSMATR
CCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCEECCCEEEEHHHHHHHHHH
EQVEAAGAAYARFRTGRADGLAIRHGAVVRTGLRGLVQGLLHLNLKRRILWAQAGGMVWF
HHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LAALVAVEALGGAGVAAVRPWLWGGFALALASSFAAGTMLLARVHRPVRHMLDFALRMGA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GDLTTRFEHRSADEIGALAQAMQTMQRSLQSVVHEIQEGMASISTATRQVAAGNNDLSQR
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TEQQAAALEQTASSMEELTSTVRQNADNARQASGLAANASETALRGGEVVGRVVQTMDEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NDASKKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHH
KEIKGLIGDTVERVDNGSALVGQAGKTMEEIVQAVKRVTDIMGEISAASAEQSAGIEQVN
HHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHH
QAVAQMDEGTQQNAALVEEAAAAAGSLEEQAMRLRDAIATFRVSMQAEVRPQRLPAHARA
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHH
DAAQSLAQA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]