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The map label for this gene is pdxA [H]

Identifier: 116694171

GI number: 116694171

Start: 243569

End: 244585

Strand: Direct

Name: pdxA [H]

Synonym: H16_B0216

Alternate gene names: 116694171

Gene position: 243569-244585 (Clockwise)

Preceding gene: 116694170

Following gene: 116694172

Centisome position: 8.36

GC content: 70.99

Gene sequence:

>1017_bases
ATGAATTCCCGTCCAAGAATCGCCATGGTGCTGGGCGACCCCGCCGGCATCGGCCCCGAACTGATCGCCAGGCTGCTGGC
CGACCCCGCGACCGCCGTGCAGGCCGAGATCCTGTTGATCGCCGACCGCGACGAATGGCGCCACGGCATGCGGATCGCAG
GCGTCGAGCTGGCGCTGGCCGAGACCGATGCGCCCGCCTTTGCCGACGATGGCAAGCCGCGCCTGTACCACTGGCAGCTG
CCGGAGCGCCCGGCGTATGCGCGCGGCCAAGCCAGTGCCGAGGGCGGGCGCTACAGCCTGGGCACGCTGGCGCTGGCACT
GCAGCTGGCGCAAGCGGGCCAGGCCGACGCGATCCTGTTCGGGCCGCTCAACAAGAGCTCGCTGCACGCCGCCGGCATGG
CGCACAGCGATGAGCTGCACTGGTTTGCCGAGCAGCTTGGCTGCCACGGCAACTTCTGCGAGTTCAATGTCCTGGACGGG
CTGTGGACCTCGCGCGTGACCTCGCACGTGGCGCTCAAGGACGTGCCGGCGATGATCACGCAGGAACGCGTGGGCGGCGC
CATCGACCTGATTGACCAGGCCCTGCGCCGCGCCGGCATGGCGCGCCCGCGCATCGCGGTGTGCGGCCTGAACCCGCACA
ACGGCGACAACGGCGCCTTCGGCCGCGAGGAGATCGACGTGATCGCCCCGGCCGTGGCCGCGGCGCGTGAGCGCGGCGTG
GCGGCAGACGGTCCGTTCCCGGCCGACACCATCTTCCTGAAGGTGCAGGGCGGGCCGTCGCAGCGGCAGTTCGATGCTAT
CGTCACCATGTACCACGACCAGGGCCAGATCGGCATCAAGCTGATGGGCTTCTCGCGCGGCGTGACGGTGCAGGGCGGGC
TGCCGGTGCCGATCACCACGCCCGCGCATGGCACCGCGTTCGACATCACGCAGCAGGGCCGCGCCGATCCGGGCGCCACG
CTGCAGGCATTCCAGATCGCCTGCCGCATGGGCGCGCAACGGCGCGCCACAGCCTAG

Upstream 100 bases:

>100_bases
GCGCAGTTCGATGCCTTCTCGCGTGCCGAGTATGTGCGCTATGGCAAGCTGATCGCTGAACTGGGCGTCAAGCTCGACCA
ATAACAACCCCGGAAGTCCA

Downstream 100 bases:

>100_bases
CCACCACCTTCACCACACCAAATCCAGCAAGACCGCCCCCGGCGCGGCCGGGGAGCGTTCGCGCCAACGCATCGCCATCA
GGAGCTGAACATGAAGATCA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 2 [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNSRPRIAMVLGDPAGIGPELIARLLADPATAVQAEILLIADRDEWRHGMRIAGVELALAETDAPAFADDGKPRLYHWQL
PERPAYARGQASAEGGRYSLGTLALALQLAQAGQADAILFGPLNKSSLHAAGMAHSDELHWFAEQLGCHGNFCEFNVLDG
LWTSRVTSHVALKDVPAMITQERVGGAIDLIDQALRRAGMARPRIAVCGLNPHNGDNGAFGREEIDVIAPAVAAARERGV
AADGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITTPAHGTAFDITQQGRADPGAT
LQAFQIACRMGAQRRATA

Sequences:

>Translated_338_residues
MNSRPRIAMVLGDPAGIGPELIARLLADPATAVQAEILLIADRDEWRHGMRIAGVELALAETDAPAFADDGKPRLYHWQL
PERPAYARGQASAEGGRYSLGTLALALQLAQAGQADAILFGPLNKSSLHAAGMAHSDELHWFAEQLGCHGNFCEFNVLDG
LWTSRVTSHVALKDVPAMITQERVGGAIDLIDQALRRAGMARPRIAVCGLNPHNGDNGAFGREEIDVIAPAVAAARERGV
AADGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITTPAHGTAFDITQQGRADPGAT
LQAFQIACRMGAQRRATA
>Mature_338_residues
MNSRPRIAMVLGDPAGIGPELIARLLADPATAVQAEILLIADRDEWRHGMRIAGVELALAETDAPAFADDGKPRLYHWQL
PERPAYARGQASAEGGRYSLGTLALALQLAQAGQADAILFGPLNKSSLHAAGMAHSDELHWFAEQLGCHGNFCEFNVLDG
LWTSRVTSHVALKDVPAMITQERVGGAIDLIDQALRRAGMARPRIAVCGLNPHNGDNGAFGREEIDVIAPAVAAARERGV
AADGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITTPAHGTAFDITQQGRADPGAT
LQAFQIACRMGAQRRATA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=337, Percent_Identity=32.3442136498516, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35900; Mature: 35900

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRPRIAMVLGDPAGIGPELIARLLADPATAVQAEILLIADRDEWRHGMRIAGVELALA
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHEEEEEEEEECCHHHHCCCEEEEEEEEEE
ETDAPAFADDGKPRLYHWQLPERPAYARGQASAEGGRYSLGTLALALQLAQAGQADAILF
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
GPLNKSSLHAAGMAHSDELHWFAEQLGCHGNFCEFNVLDGLWTSRVTSHVALKDVPAMIT
CCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
QERVGGAIDLIDQALRRAGMARPRIAVCGLNPHNGDNGAFGREEIDVIAPAVAAARERGV
HHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
AADGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITT
CCCCCCCCCEEEEEECCCCCCHHEEEEEEEEECCCCEEEEEEEECCCEEEECCCCCEEEC
PAHGTAFDITQQGRADPGATLQAFQIACRMGAQRRATA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNSRPRIAMVLGDPAGIGPELIARLLADPATAVQAEILLIADRDEWRHGMRIAGVELALA
CCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHEEEEEEEEECCHHHHCCCEEEEEEEEEE
ETDAPAFADDGKPRLYHWQLPERPAYARGQASAEGGRYSLGTLALALQLAQAGQADAILF
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
GPLNKSSLHAAGMAHSDELHWFAEQLGCHGNFCEFNVLDGLWTSRVTSHVALKDVPAMIT
CCCCCCCCHHCCCCCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
QERVGGAIDLIDQALRRAGMARPRIAVCGLNPHNGDNGAFGREEIDVIAPAVAAARERGV
HHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
AADGPFPADTIFLKVQGGPSQRQFDAIVTMYHDQGQIGIKLMGFSRGVTVQGGLPVPITT
CCCCCCCCCEEEEEECCCCCCHHEEEEEEEEECCCCEEEEEEEECCCEEEECCCCCEEEC
PAHGTAFDITQQGRADPGATLQAFQIACRMGAQRRATA
CCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]