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The map label for this gene is cmpR [H]

Identifier: 116694064

GI number: 116694064

Start: 118902

End: 119792

Strand: Direct

Name: cmpR [H]

Synonym: H16_B0104

Alternate gene names: 116694064

Gene position: 118902-119792 (Clockwise)

Preceding gene: 116694062

Following gene: 116694066

Centisome position: 4.08

GC content: 69.92

Gene sequence:

>891_bases
ATGCTCATCGCCCAGCTCAAGTCCTTCTTCATGGTGGCCCGCATCGGCAGCGTCACGCAGGCCGCCAAGCGCCTGGGCCT
GTCGCAGCCCACCATCACCGCGCAGATCCGCGCGCTGGAAGAAGCCTACGGGGTCGAGCTGTTCCACCGCGGCGGGCGCC
GCCTGGCGCTGTCAGACGCGGGGCTGGCATTGCTGCCGCGCGTCGAGGCGCTGGTGCAGCAGGAAACCGAGATCGACTTC
TTCCTGCGCCATTCGGGCGACCTGCGCACCGGCAGCCTGCGCGTGGGCGCGACCGCGCCCTACTATGTGCTGGAGCTGAT
CCGCGGCTTCAGCGAGCGCTTTCCCGCCATCGATGTCAGCGTGGTGACGGGCAATTCGCAGGAGGTGCTGGAAGCGCTGC
AGGAATACCGCGTCGATATCGCCACCTCGTCGCAGCGGGTGGACGATGCGCGCCTGTCGCGCGTGCTGCTGGGCGTGGAC
CCGCTGATGCTGGTGGTGCATCGCACCCATGCGCTGGCCGGGCACACCGAAGTGGCCGTCAGTGCGCTGGCGGGCTGCCG
CCTGCTGATGCGCGAGCTCGGGTCGACCACGCGCATCGCAACCGAAGACATGCTGGCGCAGGCGCGCGTGAGCCCCGCCG
CGCAGATGGAGATCGGCAGCCGGGAGTCGATCCGCGAGGCGGTGATCCGCAACCTGGGCGTATCGGTGATCGCCCGGCAC
GAGGTGCCGAGCCATCCGGACCTGCGCGTGCTGGGCTTCACCGATGCCTCGCCCTGCCTGCACGAGTATCTCTACTGCCT
GCGCGAGCGGCGCGGCGCCAGGCTGATCGATGCCTTCGTCGCACTGGCCGAGCCGCCGCAGGGGCGGCAGGAATCGGGCG
CGGACCGCTAA

Upstream 100 bases:

>100_bases
ACCGGGTGGCTTGGTGCAGTCCATTAGAATACCGCTTCACCGCGGCCGGCGCCCAGGCGCCCGCCGCCTTGCCTTGCCCT
TAGCGACATCCCTCGGCCGC

Downstream 100 bases:

>100_bases
GCCGTCATCTTCAGGCACTGCTCCATGCAGGCTGCGCAGGCGCGGGCGCATTCCTGGCAGTGCTCGTTGTCATGGTGCTC
GCATTCCTCCTTGCACCACT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLALLPRVEALVQQETEIDF
FLRHSGDLRTGSLRVGATAPYYVLELIRGFSERFPAIDVSVVTGNSQEVLEALQEYRVDIATSSQRVDDARLSRVLLGVD
PLMLVVHRTHALAGHTEVAVSALAGCRLLMRELGSTTRIATEDMLAQARVSPAAQMEIGSRESIREAVIRNLGVSVIARH
EVPSHPDLRVLGFTDASPCLHEYLYCLRERRGARLIDAFVALAEPPQGRQESGADR

Sequences:

>Translated_296_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLALLPRVEALVQQETEIDF
FLRHSGDLRTGSLRVGATAPYYVLELIRGFSERFPAIDVSVVTGNSQEVLEALQEYRVDIATSSQRVDDARLSRVLLGVD
PLMLVVHRTHALAGHTEVAVSALAGCRLLMRELGSTTRIATEDMLAQARVSPAAQMEIGSRESIREAVIRNLGVSVIARH
EVPSHPDLRVLGFTDASPCLHEYLYCLRERRGARLIDAFVALAEPPQGRQESGADR
>Mature_296_residues
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDAGLALLPRVEALVQQETEIDF
FLRHSGDLRTGSLRVGATAPYYVLELIRGFSERFPAIDVSVVTGNSQEVLEALQEYRVDIATSSQRVDDARLSRVLLGVD
PLMLVVHRTHALAGHTEVAVSALAGCRLLMRELGSTTRIATEDMLAQARVSPAAQMEIGSRESIREAVIRNLGVSVIARH
EVPSHPDLRVLGFTDASPCLHEYLYCLRERRGARLIDAFVALAEPPQGRQESGADR

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=31.9672131147541, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693105, Length=271, Percent_Identity=26.1992619926199, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI157672245, Length=275, Percent_Identity=28.3636363636364, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082132, Length=279, Percent_Identity=27.9569892473118, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790399, Length=309, Percent_Identity=23.3009708737864, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788748, Length=277, Percent_Identity=27.0758122743682, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787806, Length=302, Percent_Identity=26.8211920529801, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=27.0161290322581, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787530, Length=299, Percent_Identity=25.752508361204, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786401, Length=151, Percent_Identity=29.1390728476821, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=132, Percent_Identity=32.5757575757576, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=237, Percent_Identity=27.4261603375527, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=244, Percent_Identity=27.0491803278689, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32461; Mature: 32461

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GLALLPRVEALVQQETEIDFFLRHSGDLRTGSLRVGATAPYYVLELIRGFSERFPAIDVS
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEE
VVTGNSQEVLEALQEYRVDIATSSQRVDDARLSRVLLGVDPLMLVVHRTHALAGHTEVAV
EEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
SALAGCRLLMRELGSTTRIATEDMLAQARVSPAAQMEIGSRESIREAVIRNLGVSVIARH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCHHEEEEC
EVPSHPDLRVLGFTDASPCLHEYLYCLRERRGARLIDAFVALAEPPQGRQESGADR
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLIAQLKSFFMVARIGSVTQAAKRLGLSQPTITAQIRALEEAYGVELFHRGGRRLALSDA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
GLALLPRVEALVQQETEIDFFLRHSGDLRTGSLRVGATAPYYVLELIRGFSERFPAIDVS
CHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCEEEE
VVTGNSQEVLEALQEYRVDIATSSQRVDDARLSRVLLGVDPLMLVVHRTHALAGHTEVAV
EEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHH
SALAGCRLLMRELGSTTRIATEDMLAQARVSPAAQMEIGSRESIREAVIRNLGVSVIARH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCHHEEEEC
EVPSHPDLRVLGFTDASPCLHEYLYCLRERRGARLIDAFVALAEPPQGRQESGADR
CCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]