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The map label for this gene is yjiA [H]

Identifier: 116691107

GI number: 116691107

Start: 3402469

End: 3403650

Strand: Direct

Name: yjiA [H]

Synonym: Bcen2424_3089

Alternate gene names: 116691107

Gene position: 3402469-3403650 (Clockwise)

Preceding gene: 116691106

Following gene: 116691108

Centisome position: 97.66

GC content: 61.76

Gene sequence:

>1182_bases
ATGTTTCAATGGATGGTTGTGCGCCCCGGCTCGCAGCGCGAGGGCGCGACGCACATCCTGGTTTTGACCCCGATTCACGA
ACCACAGGCGACCGACATGGCCACTCCCGTCACCATCCTTACCGGCTTCCTCGGCAGCGGCAAGACGACGCTGCTCAAGC
GCATCCTGAACGAACAGCACGGCATGAAGATCGCCGTGATCGAGAACGAGTTCGGCGAAGAGAACATCGACAACGAAATC
CTCGTGCAGGATTCGAACGAGCAGATCATCCAGATGAGCAACGGCTGCATCTGCTGCACGATCCGCGGCGACCTCGCCCG
CGCGCTCGGCGATCTGGCCGCGAAGAAGCGCGAGGGCAAGCTCGACTTCGACCGCATCGTGATCGAGACGACCGGCCTCG
CGAACCCGGGCCCCGTCGCACAAACGTTCTTCATCGACAGCGAAATCGCCGACGACTTCCTGCTGGACGCGGTCATCACG
CTGGTCGACGCGAAGCACGCGAACGCGCAGCTCGACGAACACGAGGTGGTGCAGCGCCAGGTCGGTTTCGCCGATCGCCT
GTTCATCACGAAGTCGGATCTCGTCGACGACCAGACCGTCGCGGGCCTCAAGCACCGCCTGATGCACATGAACCCGAAGG
CCGCGATCAAGGTCGTGAATTTCGGCGAAGCGGACATCAAGGAAATCTTCGACCTGCGCGGCTTCAACCTGAACGCGAAG
CTCGAGATCGATCCCGATTTCCTCGCCGAGGACGATCACGCGCACGATCATCACGATCACGACCATGATCACGATCACGC
GAATTGCGACCACGATCACGGCCAATGCGCGCACGATCACGACCACGGCCACCACCACCACAATCATCACCACGCGCACC
ACGACGACAAGATCAAGTCGTTCGTGTATCGCAACGACCGCCCGTTCGACCCGAACAAGCTGGAAGACTTCCTCGGCGGC
ATCCTGCAGATCTACGGCGAGCGGATGCTGCGCTACAAGGGCGTGCTGTACATGAAGGGCGTCGACCGCAAGGTCGTGTT
CCAGGGCGTGCACCAGATGATGGGCAGCGACCTCGCGGCGAAGTGGCTGCCGGTCGAGAAGAAGACCAACAAGATGGTGT
TCATCGGCGTCGACCTGCCGCAGGACCTGATCACCGACGGCCTCGACGCCTGCCTCGCCTGA

Upstream 100 bases:

>100_bases
TCTGATCGCCCCGATCTAGCGCGGACAACCGCGCCCGCCCTCCGTTGGCGGCGCAGCGCCCCCGCCTGTCGTTCGGACGA
CGGGCGGGGGCTTGACAGGT

Downstream 100 bases:

>100_bases
CCCGTGCGGGCGCCCGCCGTGCGCCCGCTGCCCGGCCGCCCGCACCGGCGGCCGCGGCGGTCGGGCGGCGCCTTTTCCGG
GCAGGGTTTCGCCGTCATCG

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MFQWMVVRPGSQREGATHILVLTPIHEPQATDMATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEI
LVQDSNEQIIQMSNGCICCTIRGDLARALGDLAAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVIT
LVDAKHANAQLDEHEVVQRQVGFADRLFITKSDLVDDQTVAGLKHRLMHMNPKAAIKVVNFGEADIKEIFDLRGFNLNAK
LEIDPDFLAEDDHAHDHHDHDHDHDHANCDHDHGQCAHDHDHGHHHHNHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGG
ILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMGSDLAAKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA

Sequences:

>Translated_393_residues
MFQWMVVRPGSQREGATHILVLTPIHEPQATDMATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEI
LVQDSNEQIIQMSNGCICCTIRGDLARALGDLAAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVIT
LVDAKHANAQLDEHEVVQRQVGFADRLFITKSDLVDDQTVAGLKHRLMHMNPKAAIKVVNFGEADIKEIFDLRGFNLNAK
LEIDPDFLAEDDHAHDHHDHDHDHDHANCDHDHGQCAHDHDHGHHHHNHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGG
ILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMGSDLAAKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
>Mature_393_residues
MFQWMVVRPGSQREGATHILVLTPIHEPQATDMATPVTILTGFLGSGKTTLLKRILNEQHGMKIAVIENEFGEENIDNEI
LVQDSNEQIIQMSNGCICCTIRGDLARALGDLAAKKREGKLDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVIT
LVDAKHANAQLDEHEVVQRQVGFADRLFITKSDLVDDQTVAGLKHRLMHMNPKAAIKVVNFGEADIKEIFDLRGFNLNAK
LEIDPDFLAEDDHAHDHHDHDHDHDHANCDHDHGQCAHDHDHGHHHHNHHHAHHDDKIKSFVYRNDRPFDPNKLEDFLGG
ILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMGSDLAAKWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=382, Percent_Identity=30.1047120418848, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI146231952, Length=382, Percent_Identity=30.6282722513089, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI33469141, Length=361, Percent_Identity=30.7479224376731, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI148727351, Length=382, Percent_Identity=30.1047120418848, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI223941779, Length=382, Percent_Identity=29.8429319371728, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI223941776, Length=352, Percent_Identity=29.5454545454545, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI119120938, Length=165, Percent_Identity=41.8181818181818, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI87082430, Length=349, Percent_Identity=38.10888252149, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1788499, Length=177, Percent_Identity=31.638418079096, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=237, Percent_Identity=29.1139240506329, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 44243; Mature: 44243

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQWMVVRPGSQREGATHILVLTPIHEPQATDMATPVTILTGFLGSGKTTLLKRILNEQH
CCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
GMKIAVIENEFGEENIDNEILVQDSNEQIIQMSNGCICCTIRGDLARALGDLAAKKREGK
CCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHCCCC
LDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVITLVDAKHANAQLDEHEVVQRQ
CCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VGFADRLFITKSDLVDDQTVAGLKHRLMHMNPKAAIKVVNFGEADIKEIFDLRGFNLNAK
HCCHHEEEEEHHHCCCHHHHHHHHHHHHCCCCHHEEEEEECCCHHHHHHHHHCCCCCCEE
LEIDPDFLAEDDHAHDHHDHDHDHDHANCDHDHGQCAHDHDHGHHHHNHHHAHHDDKIKS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMGSDLAA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCHHH
KWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
HCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MFQWMVVRPGSQREGATHILVLTPIHEPQATDMATPVTILTGFLGSGKTTLLKRILNEQH
CCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHC
GMKIAVIENEFGEENIDNEILVQDSNEQIIQMSNGCICCTIRGDLARALGDLAAKKREGK
CCEEEEEECCCCCCCCCCEEEEECCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHCCCC
LDFDRIVIETTGLANPGPVAQTFFIDSEIADDFLLDAVITLVDAKHANAQLDEHEVVQRQ
CCCEEEEEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
VGFADRLFITKSDLVDDQTVAGLKHRLMHMNPKAAIKVVNFGEADIKEIFDLRGFNLNAK
HCCHHEEEEEHHHCCCHHHHHHHHHHHHCCCCHHEEEEEECCCHHHHHHHHHCCCCCCEE
LEIDPDFLAEDDHAHDHHDHDHDHDHANCDHDHGQCAHDHDHGHHHHNHHHAHHDDKIKS
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
FVYRNDRPFDPNKLEDFLGGILQIYGERMLRYKGVLYMKGVDRKVVFQGVHQMMGSDLAA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCHHH
KWLPVEKKTNKMVFIGVDLPQDLITDGLDACLA
HCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]