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The map label for this gene is rutG [H]

Identifier: 116691031

GI number: 116691031

Start: 3325093

End: 3326400

Strand: Reverse

Name: rutG [H]

Synonym: Bcen2424_3013

Alternate gene names: 116691031

Gene position: 3326400-3325093 (Counterclockwise)

Preceding gene: 116691032

Following gene: 116691029

Centisome position: 95.48

GC content: 68.58

Gene sequence:

>1308_bases
ATGTCCGATTCCTACTTCCCGCGCTGGCGGGTCCAGCCGACCGGCGCGGCCTCGCGCGTCGTCGGCCCCGACGAGCGCCT
CGCGTGGCCGCAGATGATCGCGATGGGTGTGCAGCACGTCGTCGCGATGTTCGGTTCGACCGTGCTCGCGCCGCTGCTGA
TGGGCTTCGACCCGAACCTGTGCATTTTCATGTCGGGCATCGGCACGCTGCTGTTCTTCGTGCTGGTCGGCGGCCGCGTG
CCGAGCTACCTCGGCTCGAGCTTCGCGTTCATCGGCCTGGTGATCGCGGTGACGGGCTATGGCGGCAGCGGCCCGAACCC
GAACATTCCGGTCGCGCTCGGCGGGATCGTCGCGTGCGGCGTCGTGTACGTCGCGCTCGGCGCGCTGGTGCAGGCGATCG
GCACGCGCTGGATCGAGACGCTGATGCCGCCCGTCGTGACCGGCGCGGTGGTCGCGGTGATCGGGCTGAACCTCGCGCCG
ATCGCGGTCAAGGGCGTGTCGGGCTCGACCTTCGAATCGGTGATGGCGCTCGTCACGGTGCTGTGCGTCGGCGGCGTCGC
GGTGTTCGCGCGCGGGATGATGCAGCGCCTCTTGATCCTCGTCGGGCTCGTGATCGCGTACGTGATCTACGCGATCACGA
CCAACGGGATGGGCCTCGGCAAGCCGATCGATTTCGCGATCGTCGCGCAGGCCGCGTGGTTCGGCGTGCCGAGCTTCCGC
GCGCCGGTGTTCGATCCGCACGCGATGCTGATGCTCGCGCCGATCGCGGTGATCCTGGTCGCGGAGAACCTGGGCCACAT
CAAGGCCGTCAGCGCCATGACGGGCACCAACCTCGACCGCTACGTCGGTCGCGCGTTCATCGGCGACGGGCTCGCGACGA
TCGTCTCGGGCAGCGTCGGCGGCACGGGCGTGACCACCTACGCGGAGAACATCGGCGTGATGGCCGTCACGCGGATCTAT
TCGACGCTGGTGTTCGCGGTTGCCGCGCTGATCGCGATCGGGCTCGGCTTCTCGCCGAAGTTCGGTGCGGTGATCCAGAC
GATTCCGGGCCCCGTGCTCGGCGGCGTATCGATCGTGGTGTTCGGGCTGATCGCGGTGACGGGCGCGCGGATCTGGGTCG
TCAACAAGGTCGACTTCTCCGACAACCGCAACCTGATCGTCGCGGCCGTCACGCTGGTGCTCGGCGCCGGCGACTTCTCG
CTGAAGATCGGCGGCTTCGGGCTCGGCGGGATCGGCACCGCGACGTTCGGCGCGATCATCCTGTACGCGATCCTGCGCAA
GGAAAAGGAACCGGGCCCGGTGGTCTGA

Upstream 100 bases:

>100_bases
CGCTTGCCAGCCCCCATTCCGCTCCGTAAACTCGCGCCAGATTCCAGACCGGCGCATCCCTGGCAGCCGGCGACCGACGA
CCGACAGGAGCGCTTTCCCC

Downstream 100 bases:

>100_bases
TTCGGGAGCGGGCGGTGCAATGCCGCCCGTCGTTGTGCATACCGCCGTTGTGCTCACCTCACGCGCCGGTATTCGACTGC
CCCTGCAGCCACGCGCAGAA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSDSYFPRWRVQPTGAASRVVGPDERLAWPQMIAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIVACGVVYVALGALVQAIGTRWIETLMPPVVTGAVVAVIGLNLAP
IAVKGVSGSTFESVMALVTVLCVGGVAVFARGMMQRLLILVGLVIAYVIYAITTNGMGLGKPIDFAIVAQAAWFGVPSFR
APVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTNLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIY
STLVFAVAALIAIGLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV

Sequences:

>Translated_435_residues
MSDSYFPRWRVQPTGAASRVVGPDERLAWPQMIAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIVACGVVYVALGALVQAIGTRWIETLMPPVVTGAVVAVIGLNLAP
IAVKGVSGSTFESVMALVTVLCVGGVAVFARGMMQRLLILVGLVIAYVIYAITTNGMGLGKPIDFAIVAQAAWFGVPSFR
APVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTNLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIY
STLVFAVAALIAIGLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFS
LKIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV
>Mature_434_residues
SDSYFPRWRVQPTGAASRVVGPDERLAWPQMIAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRVP
SYLGSSFAFIGLVIAVTGYGGSGPNPNIPVALGGIVACGVVYVALGALVQAIGTRWIETLMPPVVTGAVVAVIGLNLAPI
AVKGVSGSTFESVMALVTVLCVGGVAVFARGMMQRLLILVGLVIAYVIYAITTNGMGLGKPIDFAIVAQAAWFGVPSFRA
PVFDPHAMLMLAPIAVILVAENLGHIKAVSAMTGTNLDRYVGRAFIGDGLATIVSGSVGGTGVTTYAENIGVMAVTRIYS
TLVFAVAALIAIGLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVDFSDNRNLIVAAVTLVLGAGDFSL
KIGGFGLGGIGTATFGAIILYAILRKEKEPGPVV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=423, Percent_Identity=69.5035460992908, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1788843, Length=427, Percent_Identity=37.0023419203747, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI87082181, Length=477, Percent_Identity=26.2054507337526, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1790087, Length=470, Percent_Identity=24.8936170212766, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082178, Length=410, Percent_Identity=25.8536585365854, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558856, Length=201, Percent_Identity=29.3532338308458, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=164, Percent_Identity=32.9268292682927, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=166, Percent_Identity=31.9277108433735, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542262, Length=114, Percent_Identity=35.9649122807018, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356175, Length=177, Percent_Identity=32.7683615819209, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44669; Mature: 44538

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDSYFPRWRVQPTGAASRVVGPDERLAWPQMIAMGVQHVVAMFGSTVLAPLLMGFDPNL
CCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH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HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]