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The map label for this gene is yjcC [H]

Identifier: 116690956

GI number: 116690956

Start: 3246422

End: 3247708

Strand: Reverse

Name: yjcC [H]

Synonym: Bcen2424_2938

Alternate gene names: 116690956

Gene position: 3247708-3246422 (Counterclockwise)

Preceding gene: 116690958

Following gene: 116690955

Centisome position: 93.22

GC content: 71.41

Gene sequence:

>1287_bases
ATGACGATCGTGCAACAGGAGCGTCCGGCCGCCGCGTCGCCGTACCGGTTCGAGCGGGAGATGAGCTCCGGCCTCGAACG
GCTGGCGACGCAGCACCGCGACCTGACGCTCACGACCGTGTTCCAGCCGATATTCAGCCTGTCGCATCAGCGCGCGGTGG
GCTACGAGGCGCTGCTGCGCGCGCACGATGCGCTCGACCGCGCCGTGTCGCCGCTCGACGTGTTCGGCGAAGCCGCGCGC
CGGGACGAACTGCTGCAGCTCGACCGGCTCGCGCAGGCGCTGCATCTGGAGAATTTCGCGCTGCTCGGCGCGGAGCGCGA
GTGGCTGTTTCTCAACGTCCATCCGGGCGTGCTCACCGACCCGTTCCAGGCGGCCGCGCTGCTCGCGAACCTGAAGCGGC
TCGGCATGCCGCCCCGCCGCATCGTGCTCGAGGTGCTCGAACAGCGCGCGGACGACGTCGAGCGGCTCGCGGAGGCCGTG
CGCGAATTCCGCACGCACGGCTTCCTGATCGCGCTCGACGATTTCGGCGCGGGCCACTCGAACATCGAACGGATCTGGCA
ACTGAACCCGGACATCGTGAAGCTCGACCGCATCATGCTGTCGCACGCGGCGCACCGCACCGGGCTCACCGCGATCCTGC
ACGGGCTCGTGACGCTGTTGCACGAGGCCGGCAAGCTGGTGCTCGTCGAAGGGATCGAGACCGAGCACGAAGCGCAGATC
GCGCTGTCGTGCGAGGCCGATTTCGTGCAGGGCTACTACTTCGGCCGCCCGGCGCCGGGGCTGCCCGACAGCGCGGCCGC
GACCGGCTGCATCGGCGAGCTGACCGAGCGCTTTCGTCAGCAGACCGAAGCGCGCGAGCGGCGCGACACGCAGCGGCTCG
CCCCGTACCTGCGCGCGTTCGAACGCGCGGCCGAGCGCCTCGAGGCCGGCGAGCCGCTCGACGAGGTGTGCTGGAATTTC
CTCGCGCTCGACGCCGCCGCGCGCTGCTTCCTGCTCGACGCGCAGGGCCGGCAGTCGGGCCGCAACGTCGTGCTGCGCGC
CGATCGCGCGCTGGCCGAGGCGCGCTTTTCGCCGCTGGCGGACGCGCAGGGCGCGAACTGGCTGCGCCGGCCGTATTTCC
GCTCGGCGATCGCCGAACCGGGGCGCGTGCAGGTCACGCGGCCGTACCTGTCGATCAACGAGGCGCAGCCGTGCGTGACG
CTGTCGGTGGCGGTGCGCGTCGGCGACGCGCAGCGCGTGCTGTGCGGCGATATCGACTGGCTCGACGACGACGCGCAGGC
CGCATAG

Upstream 100 bases:

>100_bases
CGCGCCGGGCAACCGAGGGTCCAACCATGACATTGCGCGCCGTCCCGTTCGTCGTCCGTTTCGGCGGACGTCGCGTTCGA
TTGCATCACCAGGAGGAAGC

Downstream 100 bases:

>100_bases
CGACGCACGGCTCGCATGCGGCGAGGGTGCGCGGGGCCGCGGGGGCGGCCGTTGCGTTCACCGCGTGCTTCCCCGACAAT
GGCGCGAGCGCGGCCGTCGT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAAR
RDELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRADDVERLAEAV
REFRTHGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTEARERRDTQRLAPYLRAFERAAERLEAGEPLDEVCWNF
LALDAAARCFLLDAQGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVT
LSVAVRVGDAQRVLCGDIDWLDDDAQAA

Sequences:

>Translated_428_residues
MTIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAAR
RDELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRADDVERLAEAV
REFRTHGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTEARERRDTQRLAPYLRAFERAAERLEAGEPLDEVCWNF
LALDAAARCFLLDAQGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVT
LSVAVRVGDAQRVLCGDIDWLDDDAQAA
>Mature_427_residues
TIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLRAHDALDRAVSPLDVFGEAARR
DELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTDPFQAAALLANLKRLGMPPRRIVLEVLEQRADDVERLAEAVR
EFRTHGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQIA
LSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTEARERRDTQRLAPYLRAFERAAERLEAGEPLDEVCWNFL
ALDAAARCFLLDAQGRQSGRNVVLRADRALAEARFSPLADAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTL
SVAVRVGDAQRVLCGDIDWLDDDAQAA

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=243, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082096, Length=151, Percent_Identity=31.1258278145695, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788502, Length=259, Percent_Identity=27.4131274131274, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787055, Length=235, Percent_Identity=28.0851063829787, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081743, Length=256, Percent_Identity=28.125, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786507, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081921, Length=234, Percent_Identity=24.3589743589744, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081845, Length=120, Percent_Identity=31.6666666666667, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI226510982, Length=155, Percent_Identity=27.0967741935484, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788849, Length=217, Percent_Identity=27.1889400921659, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 47757; Mature: 47626

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHDALDRAVSPLDVFGEAARRDELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGMPPRRIVLEVLEQRADDVERLAEAVREFRTHGFLIALDDFGAGHS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
NIERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTEARERRDTQRLAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLEAGEPLDEVCWNFLALDAAARCFLLDAQGRQSGRNVVLRADRALAEARFSPLA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEECHHHHHHHHCCCCC
DAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDW
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCCEEEECCCCC
LDDDAQAA
CCCCCCCC
>Mature Secondary Structure 
TIVQQERPAAASPYRFEREMSSGLERLATQHRDLTLTTVFQPIFSLSHQRAVGYEALLR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AHDALDRAVSPLDVFGEAARRDELLQLDRLAQALHLENFALLGAEREWLFLNVHPGVLTD
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGMPPRRIVLEVLEQRADDVERLAEAVREFRTHGFLIALDDFGAGHS
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
NIERIWQLNPDIVKLDRIMLSHAAHRTGLTAILHGLVTLLHEAGKLVLVEGIETEHEAQI
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALSCEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFRQQTEARERRDTQRLAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLEAGEPLDEVCWNFLALDAAARCFLLDAQGRQSGRNVVLRADRALAEARFSPLA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEECHHHHHHHHCCCCC
DAQGANWLRRPYFRSAIAEPGRVQVTRPYLSINEAQPCVTLSVAVRVGDAQRVLCGDIDW
CCCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCCEEEECCCCC
LDDDAQAA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]