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The map label for this gene is grx [H]

Identifier: 116690875

GI number: 116690875

Start: 3154266

End: 3154526

Strand: Reverse

Name: grx [H]

Synonym: Bcen2424_2855

Alternate gene names: 116690875

Gene position: 3154526-3154266 (Counterclockwise)

Preceding gene: 116690876

Following gene: 116690874

Centisome position: 90.55

GC content: 63.6

Gene sequence:

>261_bases
GTGAACAAGGTTTTGATGTACAGCACGCAGGTGTGTCCGTATTGCATGCAGGCCGAGCGCCTGCTGAAGCTGCGCGGCGT
CGAGCAGATCGAAAAGGTGCTGATCGATCGCGATCCGGCCCGCCGCGAAGAAATGATGACGCGCACGGGGCGCCGCACGG
TGCCGCAGATCTATATCGGCGACACGCACGTCGGCGGCTACGACGATCTGTCGAAGCTCGACCGCGAAGGCGGCCTCGTG
CCGCTTCTGCAAGCGGCCTGA

Upstream 100 bases:

>100_bases
AGGTCGAGGCGGCGGGCTACGCCGAGGTGCACGTGCTCGAAGGCGGCGTGGCCGCCTGGCAGCAGGCCGGGATGCCGGTC
GTCAAACAAGGAGTGGCGAA

Downstream 100 bases:

>100_bases
TTAGGGCAGAATGGCCGCCGGCCGCGCCGCGGGTCGGGCGCGCAGGATTCATCCGTGGCGGCCGGCGAACAGCCGGGCCG
CCCCGTCACCACTTTTAGGG

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MNKVLMYSTQVCPYCMQAERLLKLRGVEQIEKVLIDRDPARREEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLV
PLLQAA

Sequences:

>Translated_86_residues
MNKVLMYSTQVCPYCMQAERLLKLRGVEQIEKVLIDRDPARREEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLV
PLLQAA
>Mature_86_residues
MNKVLMYSTQVCPYCMQAERLLKLRGVEQIEKVLIDRDPARREEMMTRTGRRTVPQIYIGDTHVGGYDDLSKLDREGGLV
PLLQAA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=84, Percent_Identity=50, Blast_Score=88, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9839; Mature: 9839

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVLMYSTQVCPYCMQAERLLKLRGVEQIEKVLIDRDPARREEMMTRTGRRTVPQIYIG
CCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEC
DTHVGGYDDLSKLDREGGLVPLLQAA
CCCCCCCHHHHHHHHCCCCCEECCCC
>Mature Secondary Structure
MNKVLMYSTQVCPYCMQAERLLKLRGVEQIEKVLIDRDPARREEMMTRTGRRTVPQIYIG
CCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEC
DTHVGGYDDLSKLDREGGLVPLLQAA
CCCCCCCHHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]