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The map label for this gene is lptA [H]

Identifier: 116690809

GI number: 116690809

Start: 3085985

End: 3086650

Strand: Direct

Name: lptA [H]

Synonym: Bcen2424_2789

Alternate gene names: 116690809

Gene position: 3085985-3086650 (Clockwise)

Preceding gene: 116690808

Following gene: 116690810

Centisome position: 88.58

GC content: 69.07

Gene sequence:

>666_bases
ATGAACGAACCGTTCCCTCGACAGATTTCCGGCGGCGCTGCGCGCGCCGTCCGCGCCGCGCTCGCCGCGACGCTCGTGGC
GCTCCCGCTCATCGGGCTGGCGCCGCTCGCCCATGCCGAGAAGGCCGACCAGAACAAGCCGATCAACGTCGAGGCCGACA
ACCTGACCTATGACGATCTGAAGCAGGTGACGGTCGCGACCGGCAACGTCGTGATCACGAAGGGCACGATCATCATCAAG
GGCGACCGCGTCGAAGTGCGCCAGGACCCGGAAGGCTATCAGTACGCGACGTCGTTCGGCAGCGGCAAGAAGCACGCGAC
GTTCCGCCAGAAGCGCGAAGGCCTCGACGAATACATCGACGGCGACGCCGAGCGCATCGACTACGACGGCAAGCAGGATC
TCACCACGCTGACCACCGCCGCGACCGTGCGCCGCCTGCAGGGCACGTCGACGATCGCCGACACCGTGCACGGCAGCGTG
ATCACGTACGACGGCCAGCGCGACTTCTACACTGCGAAGGGCGGCAAGGACGTCGCGGCGCCGGGCAACCCGAACGGCCG
CGTGCGCGCGATGCTGTCGCCGAAGAGCGGCGGCCCCGCGCCGCTGAACGGGGCGCCGGCCAAGCTGTCGCCGTCGACCA
CGATCCAGGGGGCGCCCGGCCAATGA

Upstream 100 bases:

>100_bases
TCATCGAGCTTTACGGCAACGTGCGCGGCACGATCGCCGCGGCGGACACGTCCGGCGGCTCGAAAGGTCAACCCAAGTGA
CGCATCCCTCACGTGACTGC

Downstream 100 bases:

>100_bases
ACGCGCTCCCGAACCGCCAGCCGGCCGGCACCACGAGCTCGCTCGTCGTCCGCAACCTGAAGAAGCGCTACGGCTCGCGC
ACGGTCGTCAAGGACGTGTC

Product: OstA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLIGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKSGGPAPLNGAPAKLSPSTTIQGAPGQ

Sequences:

>Translated_221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLIGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKSGGPAPLNGAPAKLSPSTTIQGAPGQ
>Mature_221_residues
MNEPFPRQISGGAARAVRAALAATLVALPLIGLAPLAHAEKADQNKPINVEADNLTYDDLKQVTVATGNVVITKGTIIIK
GDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYIDGDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSV
ITYDGQRDFYTAKGGKDVAAPGNPNGRVRAMLSPKSGGPAPLNGAPAKLSPSTTIQGAPGQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 23284; Mature: 23284

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPFPRQISGGAARAVRAALAATLVALPLIGLAPLAHAEKADQNKPINVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIIIKGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSVITYDGQRDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKSGGPAPLNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC
>Mature Secondary Structure
MNEPFPRQISGGAARAVRAALAATLVALPLIGLAPLAHAEKADQNKPINVEADNLTYDDL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHH
KQVTVATGNVVITKGTIIIKGDRVEVRQDPEGYQYATSFGSGKKHATFRQKREGLDEYID
HEEEEECCCEEEEECEEEEECCEEEECCCCCCCEEEHHCCCCCCCHHHHHHHHHHHHHHC
GDAERIDYDGKQDLTTLTTAATVRRLQGTSTIADTVHGSVITYDGQRDFYTAKGGKDVAA
CCHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCCEEECCCCCCCCC
PGNPNGRVRAMLSPKSGGPAPLNGAPAKLSPSTTIQGAPGQ
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]