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The map label for this gene is kdsC [H]

Identifier: 116690807

GI number: 116690807

Start: 3084810

End: 3085346

Strand: Direct

Name: kdsC [H]

Synonym: Bcen2424_2787

Alternate gene names: 116690807

Gene position: 3084810-3085346 (Clockwise)

Preceding gene: 116690806

Following gene: 116690808

Centisome position: 88.54

GC content: 71.51

Gene sequence:

>537_bases
ATGAGCGCAGCGCTGACTGCGGCCGAACGCGCGAGCCGCGTGAAGCTGATGATTTTCGACGTCGACGGCGTGCTGACCGA
CGGCGGCCTGCTGTTTACCGCGGCCGGCGACGCGATGAAGTCGTTCAATTCGCTCGACGGCCACGGCGTGAAGCTGCTCG
GCGAAGCCGGCATCGCGACCGCGATCATCACGGGCCGCCGCTCGGACATCGTCGCGGCGCGCGCGAAGGAAATGAAGATC
GCGCACCTGTTCCAGGGCGTCGAGAACAAGCTCACCGTGTTCGGCGAGCTGATCGCGTCGCTCGGCCTGACGGCCGACGC
CTGCGGCTACATGGGCGACGACTGGCCCGACCTGCCGGTGATGCTGCGCTGCGGCTTCGCGACGGCCCCCGCGAACGCGC
ACCCCGAGGTGATCGCCCGCGCGCACTGGGTCGCCGAGGCCCGCGGCGGCCACGGCGCCGTGCGCGAGGTCTGCGATGCG
ATCCTGCGCGCGCAGCGCCGCTACGACGCGCTGCTCGCCGCCGCCTGCGGAGCCTGA

Upstream 100 bases:

>100_bases
TGGAGCGCCACCGGATCAACCAGATGCTGGTCGTCGATGCCGACGGCGCGCTGATCGGCGCGCTGAACATGCACGACCTG
TTTTCGAAGAAGGTGATCTG

Downstream 100 bases:

>100_bases
CCGATGAGCACGCATTTCCGCTGGACCCAGATGCTGCCGCTCGCCGCGGTCGCCGCGCTCGCAGGCGTCACGTGGTGGCT
GCTGCAGGCCACGCTGCCCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSAALTAAERASRVKLMIFDVDGVLTDGGLLFTAAGDAMKSFNSLDGHGVKLLGEAGIATAIITGRRSDIVAARAKEMKI
AHLFQGVENKLTVFGELIASLGLTADACGYMGDDWPDLPVMLRCGFATAPANAHPEVIARAHWVAEARGGHGAVREVCDA
ILRAQRRYDALLAAACGA

Sequences:

>Translated_178_residues
MSAALTAAERASRVKLMIFDVDGVLTDGGLLFTAAGDAMKSFNSLDGHGVKLLGEAGIATAIITGRRSDIVAARAKEMKI
AHLFQGVENKLTVFGELIASLGLTADACGYMGDDWPDLPVMLRCGFATAPANAHPEVIARAHWVAEARGGHGAVREVCDA
ILRAQRRYDALLAAACGA
>Mature_177_residues
SAALTAAERASRVKLMIFDVDGVLTDGGLLFTAAGDAMKSFNSLDGHGVKLLGEAGIATAIITGRRSDIVAARAKEMKIA
HLFQGVENKLTVFGELIASLGLTADACGYMGDDWPDLPVMLRCGFATAPANAHPEVIARAHWVAEARGGHGAVREVCDAI
LRAQRRYDALLAAACGA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=26.1437908496732, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI2367202, Length=160, Percent_Identity=43.75, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18607; Mature: 18475

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAALTAAERASRVKLMIFDVDGVLTDGGLLFTAAGDAMKSFNSLDGHGVKLLGEAGIAT
CCCHHHHHHHHCEEEEEEEECCCEEECCCEEEEECCHHHHHHCCCCCCCEEEEECCCCEE
AIITGRRSDIVAARAKEMKIAHLFQGVENKLTVFGELIASLGLTADACGYMGDDWPDLPV
EEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCC
MLRCGFATAPANAHPEVIARAHWVAEARGGHGAVREVCDAILRAQRRYDALLAAACGA
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAALTAAERASRVKLMIFDVDGVLTDGGLLFTAAGDAMKSFNSLDGHGVKLLGEAGIAT
CCHHHHHHHHCEEEEEEEECCCEEECCCEEEEECCHHHHHHCCCCCCCEEEEECCCCEE
AIITGRRSDIVAARAKEMKIAHLFQGVENKLTVFGELIASLGLTADACGYMGDDWPDLPV
EEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCC
MLRCGFATAPANAHPEVIARAHWVAEARGGHGAVREVCDAILRAQRRYDALLAAACGA
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]