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The map label for this gene is bah [H]

Identifier: 116690767

GI number: 116690767

Start: 3044421

End: 3045383

Strand: Reverse

Name: bah [H]

Synonym: Bcen2424_2747

Alternate gene names: 116690767

Gene position: 3045383-3044421 (Counterclockwise)

Preceding gene: 116690768

Following gene: 116690765

Centisome position: 87.41

GC content: 71.65

Gene sequence:

>963_bases
ATGAGTTGGCAAAGCAAGTTCGCCTGCTGGCTGCTGCGCTGGCAGTTTCGTCCGGAGACCACGCGCGAGGTGCTCGACCC
CGCGCGTGCCCGGCGCTTTACCGACCTGCGGATGTTCGTGCCGCGCCGCCCGCCGTCGGGCTACCGGCTGCGGCAGTGCT
ATGGCGCTGGCGATGCGCCGCTGCGCGGCGAATGGCTCGAACGCACCGATGCGGCCGCGGGGCGCGGGCCGGGCCGCACG
CTGCTGTATTTCCACGGCGGCGGTTACTACTTCTGTTCGACGAAAACCCATCGGCCGCTGGTGTTCGGGCTGACGAAGCG
CGCGGGCGTGCGTTCGTTCTCGCTCGACTACCGGCTCGCGCCCGAAAACCGCTTCCCGGCCGCGCTCGACGATGCGCTCG
CCGCGTACCGGCAACTGCTGGCGCTCGGCACGCCGCCCGAGTCGATCGTGTTCGGCGGCGATTCGGCGGGCGGCGGCCTC
GCGCTCGCGACGCTCGTCGCGCTGCGTGATCGCGGCGAGCCGCTGCCGGCCGGCGCGATCCTGTTCTCGCCGTGGACGGA
CCTGGCCGGCACCGGCGGCACGATGCGCAGCAACGACGGCGTCGACCCGATGTTCGCGGCCGCGGCGCTGCCGAAGGCGG
CGAAGCTGTATCTCGGCGACGCGCCGGCGACGCATCCGTACGCGTCGCCGTTCTACGCCGATTTCACGGGCCTGCCGCCG
CTGTATATCCAGGTCGGCAGCACCGAGGTGCTGCTCGACGATTCGCGCCGCGTCGCCGAGAAGGCAAAGGCGGCCGGCGT
TCAGGTTGAAATTGAGGTGTGGCCCGACATGCCGCACGTGTGGCAACTGTACGCGCCGATGGTGCCGGAAGCGCGCGACG
CGCTCGACCGCGCGGCCGCGTTCCTGCGCCGCGTCGCGGTCGAACGTGCGGTTCAGCGCGCGGGCGAGGCGTCGATGGCC
TGA

Upstream 100 bases:

>100_bases
CGGCGAACTGAGCGCCGGCGTTTGATGTAGAGGCACCTGTCGAGCGACGCGGGAACGTTTGAACGTACCATCGTCACACT
GTGATGACGGAGTGCGTCCG

Downstream 100 bases:

>100_bases
TAGGCGGCCTGGACGGCCACCGAGCCGTACTTGCGTTCGAGCCGGCGCACGGTGAAGTGGCCGTGCGCCATCTGCTGGAA
GTGGTCGATGAACAGCGTGT

Product: alpha/beta hydrolase domain-containing protein

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSWQSKFACWLLRWQFRPETTREVLDPARARRFTDLRMFVPRRPPSGYRLRQCYGAGDAPLRGEWLERTDAAAGRGPGRT
LLYFHGGGYYFCSTKTHRPLVFGLTKRAGVRSFSLDYRLAPENRFPAALDDALAAYRQLLALGTPPESIVFGGDSAGGGL
ALATLVALRDRGEPLPAGAILFSPWTDLAGTGGTMRSNDGVDPMFAAAALPKAAKLYLGDAPATHPYASPFYADFTGLPP
LYIQVGSTEVLLDDSRRVAEKAKAAGVQVEIEVWPDMPHVWQLYAPMVPEARDALDRAAAFLRRVAVERAVQRAGEASMA

Sequences:

>Translated_320_residues
MSWQSKFACWLLRWQFRPETTREVLDPARARRFTDLRMFVPRRPPSGYRLRQCYGAGDAPLRGEWLERTDAAAGRGPGRT
LLYFHGGGYYFCSTKTHRPLVFGLTKRAGVRSFSLDYRLAPENRFPAALDDALAAYRQLLALGTPPESIVFGGDSAGGGL
ALATLVALRDRGEPLPAGAILFSPWTDLAGTGGTMRSNDGVDPMFAAAALPKAAKLYLGDAPATHPYASPFYADFTGLPP
LYIQVGSTEVLLDDSRRVAEKAKAAGVQVEIEVWPDMPHVWQLYAPMVPEARDALDRAAAFLRRVAVERAVQRAGEASMA
>Mature_319_residues
SWQSKFACWLLRWQFRPETTREVLDPARARRFTDLRMFVPRRPPSGYRLRQCYGAGDAPLRGEWLERTDAAAGRGPGRTL
LYFHGGGYYFCSTKTHRPLVFGLTKRAGVRSFSLDYRLAPENRFPAALDDALAAYRQLLALGTPPESIVFGGDSAGGGLA
LATLVALRDRGEPLPAGAILFSPWTDLAGTGGTMRSNDGVDPMFAAAALPKAAKLYLGDAPATHPYASPFYADFTGLPPL
YIQVGSTEVLLDDSRRVAEKAKAAGVQVEIEVWPDMPHVWQLYAPMVPEARDALDRAAAFLRRVAVERAVQRAGEASMA

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=149, Percent_Identity=30.8724832214765, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786682, Length=233, Percent_Identity=32.618025751073, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567059, Length=259, Percent_Identity=28.1853281853282, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 35032; Mature: 34901

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQSKFACWLLRWQFRPETTREVLDPARARRFTDLRMFVPRRPPSGYRLRQCYGAGDAP
CCCCHHEEEEEEEEECCCCHHHHHHCHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCC
LRGEWLERTDAAAGRGPGRTLLYFHGGGYYFCSTKTHRPLVFGLTKRAGVRSFSLDYRLA
CCCHHHHHHCCCCCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEEC
PENRFPAALDDALAAYRQLLALGTPPESIVFGGDSAGGGLALATLVALRDRGEPLPAGAI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LFSPWTDLAGTGGTMRSNDGVDPMFAAAALPKAAKLYLGDAPATHPYASPFYADFTGLPP
EECCCHHHCCCCCCCCCCCCCCHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCCCCCE
LYIQVGSTEVLLDDSRRVAEKAKAAGVQVEIEVWPDMPHVWQLYAPMVPEARDALDRAAA
EEEEECCEEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHH
FLRRVAVERAVQRAGEASMA
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWQSKFACWLLRWQFRPETTREVLDPARARRFTDLRMFVPRRPPSGYRLRQCYGAGDAP
CCCHHEEEEEEEEECCCCHHHHHHCHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCC
LRGEWLERTDAAAGRGPGRTLLYFHGGGYYFCSTKTHRPLVFGLTKRAGVRSFSLDYRLA
CCCHHHHHHCCCCCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEEC
PENRFPAALDDALAAYRQLLALGTPPESIVFGGDSAGGGLALATLVALRDRGEPLPAGAI
CCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LFSPWTDLAGTGGTMRSNDGVDPMFAAAALPKAAKLYLGDAPATHPYASPFYADFTGLPP
EECCCHHHCCCCCCCCCCCCCCHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCCCCCE
LYIQVGSTEVLLDDSRRVAEKAKAAGVQVEIEVWPDMPHVWQLYAPMVPEARDALDRAAA
EEEEECCEEEEECCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHH
FLRRVAVERAVQRAGEASMA
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]