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The map label for this gene is tpm [H]

Identifier: 116690748

GI number: 116690748

Start: 3022856

End: 3023482

Strand: Reverse

Name: tpm [H]

Synonym: Bcen2424_2728

Alternate gene names: 116690748

Gene position: 3023482-3022856 (Counterclockwise)

Preceding gene: 116690749

Following gene: 116690747

Centisome position: 86.78

GC content: 71.29

Gene sequence:

>627_bases
ATGTCCGATCCGAAGCAACCGGCCGCACCGTCGGCCGCCGATTTCGCGACGCGCGACCCCGGTAGCGCATCGTTCTGGGA
CGAGCGTTTCGCACGCGGCGTGACGCCGTGGGAATTCGGCGGCGTGCCGGACGGCTTTCGCGTGTTCGCGCAGCGGCGCG
AGCCGTGCGCGGTGCTGATTCCCGGCTGCGGCAGTGCGCAGGAGGCCGGCTGGCTCGCGCAGGCCGGCTGGCCGGTGCGG
GCGATCGATTTCGCCGCGCAGGCGGTCGCTGCGGCGAAGGCGCAGCTCGGCGCGCATGCGGACGTCGTCGAACAGGCCGA
TTTTTTCCAGTACCGGCCGCCGTTCGACGTGCAGTGGGTGTACGAGCGCGCGTTCCTGTGCGCGTTGCCGCCGGGCCTGC
GCGCCGGCTATGCGGCGCGGATGGCCGAGCTGCTGCCCACGGGCGGATTGCTGGCCGGCTATTTCTTCGTGGTGGCCAAA
CCGAAGGGGCCGCCGTTCGGGATCGAGCGGGCGGAACTCGATGCGCTGCTCGCGCCGCACTTCGAGCTGCTCGAGGATTT
GCCCGTGACCGATTCGCTGGCCGTGTTCGACGGGCACGAGCGCTGGCTCACGTGGCGCCGTCGCTGA

Upstream 100 bases:

>100_bases
AGGCGTTGCTGATCTTCGGTCTGGCCGTCGGCGTCGGGGCGCTCGTCGCGCGCGTGCTGCTCGCGCTCGCGTACGGTGCT
TGATCGAAAGGAGCGCGGCG

Downstream 100 bases:

>100_bases
TGCGCGGGCGTCGCGGCCATTGCCGGAACGCGCCGGGGTTTCGGCTATAATTCAAGGTTTTGCAAGCCGTTTCCAGTTTC
TGCGGGAAAAATATCATGCC

Product: thiopurine S-methyltransferase

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSDPKQPAAPSAADFATRDPGSASFWDERFARGVTPWEFGGVPDGFRVFAQRREPCAVLIPGCGSAQEAGWLAQAGWPVR
AIDFAAQAVAAAKAQLGAHADVVEQADFFQYRPPFDVQWVYERAFLCALPPGLRAGYAARMAELLPTGGLLAGYFFVVAK
PKGPPFGIERAELDALLAPHFELLEDLPVTDSLAVFDGHERWLTWRRR

Sequences:

>Translated_208_residues
MSDPKQPAAPSAADFATRDPGSASFWDERFARGVTPWEFGGVPDGFRVFAQRREPCAVLIPGCGSAQEAGWLAQAGWPVR
AIDFAAQAVAAAKAQLGAHADVVEQADFFQYRPPFDVQWVYERAFLCALPPGLRAGYAARMAELLPTGGLLAGYFFVVAK
PKGPPFGIERAELDALLAPHFELLEDLPVTDSLAVFDGHERWLTWRRR
>Mature_207_residues
SDPKQPAAPSAADFATRDPGSASFWDERFARGVTPWEFGGVPDGFRVFAQRREPCAVLIPGCGSAQEAGWLAQAGWPVRA
IDFAAQAVAAAKAQLGAHADVVEQADFFQYRPPFDVQWVYERAFLCALPPGLRAGYAARMAELLPTGGLLAGYFFVVAKP
KGPPFGIERAELDALLAPHFELLEDLPVTDSLAVFDGHERWLTWRRR

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 22746; Mature: 22615

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPKQPAAPSAADFATRDPGSASFWDERFARGVTPWEFGGVPDGFRVFAQRREPCAVLI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
PGCGSAQEAGWLAQAGWPVRAIDFAAQAVAAAKAQLGAHADVVEQADFFQYRPPFDVQWV
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHH
YERAFLCALPPGLRAGYAARMAELLPTGGLLAGYFFVVAKPKGPPFGIERAELDALLAPH
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCCCHHHHHHHHCCH
FELLEDLPVTDSLAVFDGHERWLTWRRR
HHHHHCCCCCCCEEEECCHHHHEEECCC
>Mature Secondary Structure 
SDPKQPAAPSAADFATRDPGSASFWDERFARGVTPWEFGGVPDGFRVFAQRREPCAVLI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEE
PGCGSAQEAGWLAQAGWPVRAIDFAAQAVAAAKAQLGAHADVVEQADFFQYRPPFDVQWV
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHH
YERAFLCALPPGLRAGYAARMAELLPTGGLLAGYFFVVAKPKGPPFGIERAELDALLAPH
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHEEEEEEEECCCCCCCCCCHHHHHHHHCCH
FELLEDLPVTDSLAVFDGHERWLTWRRR
HHHHHCCCCCCCEEEECCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA